Mathematical modeling of supercritical fluid extraction of oil from canola and sesame seeds with a two-phase model was performed in this work. A model based on differential mass balance was used to correlate the experimental data. Different adsorption isotherm models (Henry, Freundlich and Brunauer, Emmet and Teller (BET)) were used to describe the equilibrium state. Three model parameters such as effective diffusivity (Deff), mass transfer coefficient (Kf) and axial dispersion coefficient (Dax) of the bed were used as fitting parameters. The experimental data for yields were obtained at pressures of 10-20 MPa, temperatures of 313-333 K and solvent flow rates of 2-4 g/min. From the results, a nonlinear adsorption isotherm exhibited better agreement with experimental data of yield than a linear model in the range of studied conditions.

Objective. The aim of this study was to determine the influence of gender on in hospital outcome in patients with ST-segment elevation myocardial infarction (STEMI) who underwent primary angioplasty (PA). Design and scope. Prospective study of a cohort of patients consecutively admitted to the Coronary Unit of a tertiary hospital in the period of January to October 2004 with the diagnoses of IAMEST and treated with PA. Patients. Consecutive sample of 86 patients with this diagnosis divided into two groups based on sex: 52 men and 34 women. Main variables of interest. In both groups, we analyzed the baseline clinical-demographic characteristics, extension of the coronary disease (ECD), success of the PA, appearance of heart failure (HF) and in-hospital mortality in the first 28 days after admission. We analyzed predictors of mortality in a multivariate model. Results. The women were older (70 ± 8 versus 65 ± 11; p = 0.02) and had greater prevalence of diabetes (37% versus 18%; p = 0.002) and hypertension (58% versus 37%; p < 0.001) than the men while the men had greater frequency of smoking (34% versus 22%; p = 0.001). There were no differences in the presence of hyperlipidemia, ECD or the success of PA. Women had a higher incidence of HF on admission (22% versus 12%; p = 0.01) and in-hospital mortality (17% versus 8%; p = 0.002). In the multivariate analyses, female sex and HF on admission continued to be predictors of in-hospital mortality. Conclusions. In our study, female gender was an independent predictor of in-hospital mortality in patients with IAMEST treated with PA.

Objetivo. Analizar la influencia del sexo en el pronóstico intrahospitalario del infarto agudo de miocardio con elevación del segmento ST (IAMEST) revascularizado mediante una angioplastia primaria (AP). Diseño y ámbito. Estudio prospectivo de una cohorte de pacientes consecutivamente ingresados en la Unidad Coronaria de un hospital terciario durante el periodo de enero a octubre de 2004, con diagnóstico de IAMEST y tratados con AP. Pacientes. Muestra consecutiva de 86 pacientes con dicho diagnóstico dividida en dos grupos en función del sexo: 52 hombres y 34 mujeres. Variables de interés principales. En ambos grupos analizamos las características clínico-demográficas basales, la extensión de la enfermedad coronaria (EEC), el éxito de la AP, la aparición de insuficiencia cardiaca (IC) y la mortalidad intrahospitalaria en los primeros 28 días tras el ingreso. Se analizaron predictores de mortalidad en un modelo multivariado. Resultados. Las mujeres presentaron mayor edad (70 ± 8 frente a 65 ± 11; p = 0,02) y prevalencia de diabetes (37% frente a 18%; p = 0,002) y de hipertensión arterial (58% frente a 37%; p < 0,001) que los hombres, mientras que estos presentaron mayor frecuencia de tabaquismo (34% frente a 22%; p = 0,001). No hubo diferencias en la presencia de hiperlipidemia, la EEC o el éxito de la AP. Las mujeres presentaron mayor incidencia de IC al ingreso (22% frente a 12%; p = 0,01) y de mortalidad intrahospitalaria (17% frente a 8%; p = 0,002). En el análisis multivariado, el sexo femenino y la IC al ingreso permanecieron como predictores de mortalidad intrahospitalaria. Conclusiones. En nuestro estudio, el sexo femenino fue un predictor independiente de mortalidad intrahospitalaria en pacientes con IAMEST tratados con AP.