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1.
Laying parameters of meat quails breeders submitted to lighting programs at growing phase
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Watanabe, Germana Costa Aguiar
; Watanabe, Pedro Henrique
; Mello, Marcelle Craveiro Abreu de
; Santos, Edibergue Oliveira dos
; Cordeiro, Carla Nágila
; Nepomuceno, Rafael Carlos
; Gomes, Thalles Ribeiro
; Freitas, Ednardo Rodrigues
.
ABSTRACT: When applied at growing phase, lighting program aims to obtain quails with body weight and physiological maturity suitable for the beginning of laying. This study evaluated lighting programs at growing phase on performance, sexual maturity and egg quality of meat quail breeders (Coturnixcoturnix) at laying phase. From 7 to 49 days of age, 300 female meat quails were subjected to three lighting programs (natural, intermittent and continuous), with 5 replicates of 20 birds each. At 49 days of age, 240 quails were transferred to a shed, maintaining the same experimental conditions. Meat quails submitted to continuous and intermittent lighting programs had higher weight of reproductive system and lower ages for first egg production and to reach 50% of egg production (P < 0.05). Quails submitted to natural lighting had lower feed intake from 49 to 70 and 71 to 92 days of age and worse feed conversion up to 114 days of age. Continuous and intermittent lighting programs resulted in more precocious quails compared to natural lighting program. Quails submitted to natural lighting at growing phase presented lower egg production during all periods, not differing for birds submitted to continuous and intermittent programs from the second period (71 to 92 days of age). Intermittent and continuous lighting result in better feed conversion of breeding quails up to 114 days and a higher percentage of laying (49 to 136 days), reducing the number of days to produce the first egg and to reach 50% of laying, in relation to natural lighting.
RESUMO: Quando aplicado na fase de crescimento, o programa de luz visa obter codornas com peso corporal e maturidade fisiológica adequados para o início da postura. Este estudo avaliou programas de iluminação na fase de crescimento sobre o desempenho, maturidade sexual e qualidade dos ovos de codornas de corte reprodutoras (Coturnix coturnix) na fase de postura. Durante o período de sete a 49 dias de idade, 300 codornas de corte fêmeas foram submetidas a três programas de iluminação (natural, intermitente e contínuo), com cinco repetições de 20 aves cada. Aos 49 dias de idade, 240 codornas foram transferidas para um galpão, mantendo a mesma distribuição experimental e submetidas às mesmas condições. As aves submetidas aos programas de iluminação contínuo e intermitente na fase de crescimento apresentaram maiores peso relativo do sistema reprodutivo e consequentemente menores idades para produção do primeiro ovo e para atingir 50% da produção de ovos (P < 0.05). As aves que receberam apenas iluminação natural apresentaram menor consumo de ração nos períodos de 49 a 70 e 71 a 92 dias de idade e pior conversão alimentar até 114 dias de idade. Os programas de iluminação contínua e intermitente na fase de crescimento resultaram em codornas mais precoces quando comparados as aves submetidas ao programa de iluminação natural. Codornas submetidas a programa de luz natural na fase de crescimento apresentaram menor produção de ovos durante todos os períodos, não diferindo das aves submetidas a programas contínuos e intermitentes a partir do segundo período (71 a 92 dias de idade). A iluminação intermitente e contínua na fase de crescimento resulta em melhor conversão alimentar de codornas reprodutoras até 114 dias e maior percentual de postura (49 a 136 dias), reduzindo o número de dias para produzir o primeiro ovo e atingir 50% de postura, em relação a iluminação natural..
2.
Dietary inclusion of parboiled whole rice bran on production of meat quails
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Freitas, Ednardo Rodrigues
; Gomes, Thalles Ribeiro
; Nepomuceno, Rafael Carlos
; Santos, Edibergue Oliveira dos
; Watanabe, Pedro Henrique
; Nascimento, Germano Augusto Jerônimo do
.
ABSTRACT The use of non-conventional feeds in poultry farming can reduce production costs, mainly because of its low cost, availability and chemical composition. Thus, parboiled whole rice bran (PWRB) appears as a potential use in feeding quails. Two experiments were carried out to evaluate the effects of the inclusion of PWRB in the diet of quails. In each experiment, a total of 288 seven-day-old European quails of both sexes, were distributed in a completely randomized design with six treatments and six replicates of eight quails each. The treatments consisted in the inclusion of PWRB in the proportions of 0; 5; 10; 15; 20 and 25% (first) and 0; 8; 16; 24; 32 and 40% (second). In the first experiment, a linear reduction in feed intake and weight gain was observed with the inclusion of PWRB above 5%, with no significant effect on feed conversion and carcass characteristics. However, there was no loss in the performance and carcass characteristics of quails fed with different levels of PWRB in comparison to the control group. In the second, it was observed that the inclusion of PWRB above 8% promoted a linear reduction in feed intake, weight gain and improvement in feed conversion, with no significant effect on carcass characteristics. However, quails fed 40% PWRB showed reduced intake and weight gain when compared to the control group. The use of PWRB provided an improvement in economic viability. Considering the effect on growth, PWRB can be used in the feeding of meat quails up to 32%.
3.
Neck circumference as a predictor of cardiometabolic risk and truncal obesity in people living with HIV
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Oliveira, Iara Katrynne Fonsêca
; Teixeira, Nayra do Socorro Caldas Carvalho de Almeida
; Rêgo, Beatriz de Mello Pereira
; Aires, Isabel Oliveira
; Rodrigues, Renata Rios Torres
; Araújo, Robson Eduardo da Silva
; Lima, Carlos Henrique Ribeiro
; Sousa, Rosana Rodrigues de
; Carvalho, Cecília Maria Resende Gonçalves de
; Costa, Dorcas Lamounier
; Santos, Marize Melo dos
; Paz, Suzana Maria Rebelo Sampaio da
; Paiva, Adriana de Azevedo
.
Abstract Introduction: recent studies have suggested the use of neck circumference as a parameter capable of identifying risks of cardiometabolic complications and the accumulation of truncal fat caused by both antiretroviral therapy and the lifestyle of people with the human immunodeficiency virus (HIV). Objective: to investigate the relationship between neck circumference and anthropometric indicators and to assess cardiometabolic risk and truncal obesity through proposed cut-off points. Methods: cross-sectional study including 233 people with HIV. Demographic, socioeconomic, lifestyle and clinical data were collected using a structured questionnaire. The anthropometric evaluation included: weight, height, body mass index (BMI) measurements; waist (WC), neck (NC), arm and arm muscle circumferences; triceps and subscapular skinfolds and their sum. ROC curves were constructed to determine the accuracy of NC in predicting cardiometabolic risk in people living with HIV. Results: the sample was 57.5 % male, with a mean age of 38.4 years (95 % CI: 37.2-39.7 years). NC showed a positive and significant correlation with all anthropometric variables analyzed (p < 0.05), and a higher correlation strength with WC and BMI. The NC cut-off point selected as a predictor of risk of cardiac metabolic complications and truncal obesity in women was ≥ 32.4 cm, considering both WC and BMI. For men, the NC cut-off points were different when considering WC (≥ 39.6 cm) and BMI (≥ 38.1 cm) as a reference. It is worth noting that NC performed well in ROC curve analysis for men, while in women it was a poor performance. Conclusion: NC proved to be a promising indicator in the assessment of nutrition and health of people living with HIV, especially in men.
Resumen Introducción: estudios recientes han sugerido el uso de la circunferencia del cuello como parámetro capaz de identificar los riesgos de complicaciones cardiometabólicas y la acumulación de grasa troncal causados tanto por la terapia antirretroviral como por el estilo de vida de las personas con el virus de la inmunodeficiencia humana (VIH). Objetivo: investigar la relación entre la circunferencia del cuello y los indicadores antropométricos y evaluar el riesgo cardiometabólico y la obesidad troncal a través de los puntos de corte propuestos. Métodos: estudio transversal que incluyó a 233 personas con VIH. Se recogieron datos demográficos, socioeconómicos, de estilo de vida y clínicos mediante un cuestionario estructurado. La evaluación antropométrica incluyó: medidas de peso, altura, índice de masa corporal (IMC); circunferencias de cintura (CC), cuello (CN), brazo (CA) y músculo del brazo (MCB); pliegues cutáneos del tríceps y subescapular y su suma. Se construyeron curvas ROC para determinar la precisión de la CN en la predicción del riesgo cardiometabólico en personas que viven con el VIH. Resultados: el 57,5 % de la muestra eran varones, con una edad media de 38,4 años (IC 95 %: 37,2-39,7 años). La CN mostró una correlación positiva y significativa (p < 0,05) con todas las variables antropométricas analizadas, y una mayor fuerza de correlación con la CC y el IMC. El punto de corte de la CN seleccionado como predictor de riesgo de complicaciones metabólicas cardiacas y obesidad troncular en mujeres fue ≥ 32,4 cm, considerando tanto la CC como el IMC. En el caso de los hombres, los puntos de corte de la CN fueron diferentes al considerar como referencia la CC (≥ 39,6 cm) y el IMC (≥ 38,1 cm). Cabe destacar que la CN obtuvo buenos resultados en el análisis de la curva ROC en el caso de los hombres, mientras que en el de las mujeres fue deficiente. Conclusión: la CN demostró ser un indicador prometedor en la evaluación de la nutrición y la salud de las personas que viven con el VIH, especialmente en los hombres.
4.
Brazilian Society of Otology task force - Otosclerosis: evaluation and treatment
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Silva, Vagner Antonio Rodrigues
; Pauna, Henrique Furlan
; Lavinsky, Joel
; Guimarães, Guilherme Corrêa
; Abrahão, Nicolau Moreira
; Massuda, Eduardo Tanaka
; Vianna, Melissa Ferreira
; Yudi Ikino, Cláudio Márcio
; Santos, Vanessa Mazanek
; Polanski, José Fernando
; Silva, Maurício Noschang Lopes da
; Sampaio, André Luiz Lopes
; Zanini, Raul Vitor Rossi
; Lourençone, Luiz Fernando Manzoni
; Denaro, Mariana Moreira de Castro
; Calil, Daniela Bortoloti
; Chone, Carlos Takahiro
; Castilho, Arthur Menino
.
Brazilian Journal of Otorhinolaryngology
- Métricas do periódico
Abstract Objectives: To review and provide evidence-based recommendations for the diagnosis and treatment of otosclerosis. Methods: Task force members were educated on knowledge synthesis methods, including electronic database search, review and selection of relevant citations, and critical appraisal of selected studies. Articles written in English or Portuguese on otosclerosis were eligible for inclusion. The American College of Physicians’ guideline grading system and the American Thyroid Association’s guideline criteria were used for critical appraisal of evidence and recommendations for therapeutic interventions. Results: The topics were divided into 2 parts: 1) Diagnosis – audiologic and radiologic; 2) Treatment – hearing AIDS, pharmacological therapy, stapes surgery, and implantable devices - bone-anchored devices, active middle ear implants, and Cochlear Implants (CI). Conclusions: The pathophysiology of otosclerosis has not yet been fully elucidated, but environmental factors and unidentified genes are likely to play a significant role in it. Women with otosclerosis are not at increased risk of worsening clinical condition due to the use of contraceptives or during pregnancy. Drug treatment has shown little benefit. If the patient does not want to undergo stapedotomy, the use of hearing aids is well indicated. Implantable systems should be indicated only in rare cases, and the CI should be indicated in cases of profound deafness.
5.
Diretriz Brasileira de Dispositivos Cardíacos Eletrônicos Implantáveis – 2023
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Teixeira, Ricardo Alkmim
; Fagundes, Alexsandro Alves
; Baggio Junior, José Mário
; Oliveira, Júlio César de
; Medeiros, Paulo de Tarso Jorge
; Valdigem, Bruno Pereira
; Teno, Luiz Antônio Castilho
; Silva, Rodrigo Tavares
; Melo, Celso Salgado de
; Elias Neto, Jorge
; Moraes Júnior, Antonio Vitor
; Pedrosa, Anisio Alexandre Andrade
; Porto, Fernando Mello
; Brito Júnior, Hélio Lima de
; Souza, Thiago Gonçalves Schroder e
; Mateos, José Carlos Pachón
; Moraes, Luis Gustavo Belo de
; Forno, Alexander Romeno Janner Dal
; D’Avila, Andre Luiz Buchele
; Cavaco, Diogo Alberto de Magalhães
; Kuniyoshi, Ricardo Ryoshim
; Pimentel, Mauricio
; Camanho, Luiz Eduardo Montenegro
; Saad, Eduardo Benchimol
; Zimerman, Leandro Ioschpe
; Oliveira, Eduardo Bartholomay
; Scanavacca, Mauricio Ibrahim
; Martinelli Filho, Martino
; Lima, Carlos Eduardo Batista de
; Peixoto, Giselle de Lima
; Darrieux, Francisco Carlos da Costa
; Duarte, Jussara de Oliveira Pinheiro
; Galvão Filho, Silas dos Santos
; Costa, Eduardo Rodrigues Bento
; Mateo, Enrique Indalécio Pachón
; Melo, Sissy Lara De
; Rodrigues, Thiago da Rocha
; Rocha, Eduardo Arrais
; Hachul, Denise Tessariol
; Lorga Filho, Adalberto Menezes
; Nishioka, Silvana Angelina D’Orio
; Gadelha, Eduardo Barreto
; Costa, Roberto
; Andrade, Veridiana Silva de
; Torres, Gustavo Gomes
; Oliveira Neto, Nestor Rodrigues de
; Lucchese, Fernando Antonio
; Murad, Henrique
; Wanderley Neto, José
; Brofman, Paulo Roberto Slud
; Almeida, Rui M. S.
; Leal, João Carlos Ferreira
.
6.
Diretriz da SBC sobre Diagnóstico e Tratamento de Pacientes com Cardiomiopatia da Doença de Chagas – 2023
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Marin-Neto, José Antonio
; Rassi Jr, Anis
; Oliveira, Gláucia Maria Moraes
; Correia, Luís Claudio Lemos
; Ramos Júnior, Alberto Novaes
; Luquetti, Alejandro Ostermayer
; Hasslocher-Moreno, Alejandro Marcel
; Sousa, Andréa Silvestre de
; Paola, Angelo Amato Vincenzo de
; Sousa, Antônio Carlos Sobral
; Ribeiro, Antonio Luiz Pinho
; Correia Filho, Dalmo
; Souza, Dilma do Socorro Moraes de
; Cunha-Neto, Edecio
; Ramires, Felix Jose Alvarez
; Bacal, Fernando
; Nunes, Maria do Carmo Pereira
; Martinelli Filho, Martino
; Scanavacca, Maurício Ibrahim
; Saraiva, Roberto Magalhães
; Oliveira Júnior, Wilson Alves de
; Lorga-Filho, Adalberto Menezes
; Guimarães, Adriana de Jesus Benevides de Almeida
; Braga, Adriana Lopes Latado
; Oliveira, Adriana Sarmento de
; Sarabanda, Alvaro Valentim Lima
; Pinto, Ana Yecê das Neves
; Carmo, Andre Assis Lopes do
; Schmidt, Andre
; Costa, Andréa Rodrigues da
; Ianni, Barbara Maria
; Markman Filho, Brivaldo
; Rochitte, Carlos Eduardo
; Macêdo, Carolina Thé
; Mady, Charles
; Chevillard, Christophe
; Virgens, Cláudio Marcelo Bittencourt das
; Castro, Cleudson Nery de
; Britto, Constança Felicia De Paoli de Carvalho
; Pisani, Cristiano
; Rassi, Daniela do Carmo
; Sobral Filho, Dário Celestino
; Almeida, Dirceu Rodrigues de
; Bocchi, Edimar Alcides
; Mesquita, Evandro Tinoco
; Mendes, Fernanda de Souza Nogueira Sardinha
; Gondim, Francisca Tatiana Pereira
; Silva, Gilberto Marcelo Sperandio da
; Peixoto, Giselle de Lima
; Lima, Gustavo Glotz de
; Veloso, Henrique Horta
; Moreira, Henrique Turin
; Lopes, Hugo Bellotti
; Pinto, Ibraim Masciarelli Francisco
; Ferreira, João Marcos Bemfica Barbosa
; Nunes, João Paulo Silva
; Barreto-Filho, José Augusto Soares
; Saraiva, José Francisco Kerr
; Lannes-Vieira, Joseli
; Oliveira, Joselina Luzia Menezes
; Armaganijan, Luciana Vidal
; Martins, Luiz Cláudio
; Sangenis, Luiz Henrique Conde
; Barbosa, Marco Paulo Tomaz
; Almeida-Santos, Marcos Antonio
; Simões, Marcos Vinicius
; Yasuda, Maria Aparecida Shikanai
; Moreira, Maria da Consolação Vieira
; Higuchi, Maria de Lourdes
; Monteiro, Maria Rita de Cassia Costa
; Mediano, Mauro Felippe Felix
; Lima, Mayara Maia
; Oliveira, Maykon Tavares de
; Romano, Minna Moreira Dias
; Araujo, Nadjar Nitz Silva Lociks de
; Medeiros, Paulo de Tarso Jorge
; Alves, Renato Vieira
; Teixeira, Ricardo Alkmim
; Pedrosa, Roberto Coury
; Aras Junior, Roque
; Torres, Rosalia Morais
; Povoa, Rui Manoel dos Santos
; Rassi, Sergio Gabriel
; Alves, Silvia Marinho Martins
; Tavares, Suelene Brito do Nascimento
; Palmeira, Swamy Lima
; Silva Júnior, Telêmaco Luiz da
; Rodrigues, Thiago da Rocha
; Madrini Junior, Vagner
; Brant, Veruska Maia da Costa
; Dutra, Walderez Ornelas
; Dias, João Carlos Pinto
.
7.
Rhizobacteria in growth and quality of açaí seedlings
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Campos, Thiago Souza
; Patrício, Murilo Paes
; Vieira, Guilherme Rodrigues
; Souza, Antonio Maricélio Borges de
; Santos, Carlos Henrique Barbosa
; Rigobelo, Everlon Cid
; Pivetta, Kathia Fernandes Lopes
.
Abstract The success of any plant development relies on healthy and vigorous seedlings, and the use of rhizobacteria is a sustainable alternative for the production of high-quality seedlings as they positively interfere in plant development. Thus, the objective of this study was to evaluate the effect of rhizobacteria on growth and quality of seedlings of açaí (Euterpe oleracea Mart.), a native palm of Brazil, which has significant ornamental value in addition to the ecological and economic role, mainly by providing sweet heart of palm and fruit pulp. The experimental design was entirely randomized. There were five treatments (Bacillus subtilis, Bacillus megaterium, Bacillus amyloliquefaciens and Azospirillum brasilense plus the absence of microorganisms - control); four replicates and ten plants per plot. The following characteristics were evaluated: shoot height (cm), root length (cm); stem diameter (mm); number of leaves; leaf area (cm2); shoot, and root as well as total dry matter (g). Shoot/root ratio was determined and Dickson Quality Index. The data were submitted to variance analysis and the means were compared using Tukey’s test at 5% probability. Pearson’s correlation matrix was also determined. The rhizobacterium Bacillus subtilis provided higher growth while Bacillus amyloliquefaciens provided lower growth and quality of açaí seedlings.
Resumo O sucesso do desenvolvimento de qualquer planta é dependente de mudas sadias e vigorosas e o uso de rizobactérias é uma alternativa sustentável para a produção de mudas de alta qualidade pois interferem positivamente no desenvolvimento das plantas. Desta forma, o objetivo deste trabalho foi avaliar o efeito de rizobactérias no crescimento e na qualidade de mudas de açaí (Euterpe oleracea Mart.) palmeira nativa do Brasil, que apresenta expressivo valor ornamental além da importância ecológica e também econômica, principalmente pelo fornecimento de palmito doce e polpa dos frutos. O delineamento experimental foi o inteiramente casualizado. Foram cinco tratamentos (Bacillus subtilis, Bacillus megaterium, Bacillus amyloliquefaciens e Azospirillum brasilense mais a ausência de microrganismos - controle); quatro repetições e dez plantas por parcela. Foram avaliadas as características: comprimento da parte aérea (cm) e do sistema radicular (cm); diâmetro do coleto (mm); número de folhas; área foliar (cm2); massa seca da parte aérea, das raízes e total (g) e determinadas: razão parte aérea/raízes e o Índice de Qualidade de Dickson. Os dados foram submetidos à análise de variância e as médias comparadas pelo teste de Tukey, a 5% de probabilidade. Foi determinada, ainda, a matriz de correlação de Pearson. A rizobactéria Bacillus subtilis proporcionou maior e Bacillus amyloliquefaciens menor crescimento e qualidade das mudas de açaí.
8.
Productive and economic performance of feedlot young Nellore bulls fed whole oilseeds
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Valeriano, Heitor Henrique Costa
; Ítavo, Luís Carlos Vinhas
; Ítavo, Camila Celeste Brandão Ferreira
; Gomes, Marina de Nadai Bonin
; Dias, Alexandre Menezes
; Difante, Gelson dos Santos
; Longhini, Vanessa Zirondi
; Gurgel, Antonio Leandro Chaves
; Arcanjo, Angelo Herbet Moreira
; Silva, Manoel Gustavo Paranhos da
; Santana, Juliana Caroline Santos
; Moura, Jessika Rodrigues de Figueiredo
.
ABSTRACT The effects of diets containing oilseeds were measured to evaluate the productive and economic parameters in the finishing of young, feedlot Nellore bulls. Twenty-four young Nellore bulls were used, with an initial body weight (BW) of 311.46±0.37 kg and 24 months of age, distributed into individual stalls ( 4 × 20 m) in a completely randomized design, totaling four treatments with six repetitions per treatment. Four diets (control, based on corn and soybean meal, and three diets containing cottonseed, soybean, and sunflower) were evaluated. Feed and orts were measured daily to calculate intake and costs. The dry matter intake of the control group was higher than soybean (10.64 kg/day), cotton (9.88 kg/day), and sunflower (9.30 kg/day) treatments, respectively. The cottonseed treatment showed the highest average neutral detergent fiber intake. There was a dietary effect of diets on average daily gain, total weight gain, and final weight. The soybean treatment showed the highest performance, total gain (232.55 kg), and final weight (544.38 kg). Oilseed intake can modify the fatty acids profile in the meat, decreasing its saturated fatty acid content. Whole soybean seed favors performance, improves feed efficiency, fatty acid profile, and fat distribution in the carcass, and can reduce production costs.
9.
Contribution of public oral pathology services to the diagnosis of oral and oropharyngeal cancer in Brazil
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LOUREDO, Brendo Vinicius Rodrigues
; CURADO, Maria Paula
; PENAFORT, Paulo Victor Mendes
; DE ARRUDA, José Alcides Almeida
; ABREU, Lucas Guimarães
; MESQUITA, Ricardo Alves
; PINTO-JÚNIOR, Décio dos Santos
; ABRAHÃO, Aline Corrêa
; ANDRADE, Bruno Augusto Benevenuto de
; AGOSTINI, Michelle
; MORAES, Renata Mendonça
; ANBINDER, Ana Lia
; DOURADO, Pedro Henrique Silva
; SANTOS, Teresa Cristina Ribeiro Bartholomeu dos
; PIRES, Fábio Ramoa
; BORDIGNON, Natalia Cristina Trentin
; GONDAK, Rogério Oliveira
; DE OLIVEIRA, Marcia Gaiger
; CARRARD, Vinicius Coelho
; MARTINS, Manoela Domingues
; SOUSA-NETO, Sebastião Silvério
; ARANTES, Diego Antônio Costa
; MENDONÇA, Elismauro Francisco
; CIESLAK-SANCHES, Silvia Roberta
; ANTUNES, Daniella Moraes
; AMARAL-SILVA, Gleyson Kleber do
; MANIERI, Patricia Rubia
; RAMALHO, Luciana Maria Pedreira
; DOS SANTOS, Jean Nunes
; LEONEL, Augusto César Leal da Silva
; PEREZ, Danyel Elias da Cruz
; VERHEUL, Hannah Carmem Carlos Ribeiro Silva
; BARROSO, Keila Martha Amorim
; RODRIGUES, Flávia Luiza Santos
; GONZAGA, Amanda Katarinny Goes
; FERNANDES, Romana Renery
; DE SOUZA, Lélia Batista
; SOUZA, Lucas Lacerda de
; PONTES, Flávia Sirotheau Corrêa
; PONTES, Hélder Antônio Rebelo
; SILVA, Caroline Alfaia
; CÂMARA, Jeconias
; LIBÓRIO-KIMURA, Tatiana Nayara
; SANTOS-SILVA, Alan Roger
; LOPES, Márcio Ajudarte
; ALMEIDA, Oslei Paes de
; ROMAÑACH, Mário José
; VARGAS, Pablo Agustin
.
Abstract This study aimed to evaluate the contribution of oral and maxillofacial pathology laboratories (OMPLs) in Brazilian public universities to the diagnosis of lip, oral cavity, and oropharyngeal squamous cell carcinoma (SCC). A cross-sectional study was performed using biopsy records from a consortium of sixteen public OMPLs from all regions of Brazil (North, Northeast, Central-West, Southeast, and South). Clinical and demographic data of patients diagnosed with lip, oral cavity, and oropharyngeal SCC between 2010 and 2019 were collected from the patients’ histopathological records. Of the 120,010 oral and maxillofacial biopsies (2010-2019), 6.9% (8,321 cases) were diagnosed as lip (0.8%, 951 cases), oral cavity (4.9%, 5,971 cases), and oropharyngeal (1.2%, 1,399 cases) SCCs. Most cases were from Brazil’s Southeast (64.5%), where six of the OMPLs analyzed are located. The predominant profile of patients with lip and oral cavity SCC was Caucasian men, with a mean age over 60 years, low schooling level, and a previous history of heavy tobacco consumption. In the oropharyngeal group, the majority were non-Caucasian men, with a mean age under 60 years, had a low education level, and were former/current tobacco and alcohol users. According to data from the Brazilian National Cancer Institute, approximately 9.9% of the total lip, oral cavity, and oropharyngeal SCCs reported over the last decade in Brazil may have been diagnosed at the OMPLs included in the current study. Therefore, this data confirms the contribution of public OMPLs with respect to the important diagnostic support they provide to the oral healthcare services extended by the Brazilian Public Health System.
10.
Non-Invasive Methods and the Use of Infiltrating Resins for the Control of Caries Progression in Deciduous Teeth: A Systematic Review and Meta-Analysis
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Almeida, Híttalo Carlos Rodrigues de
; Oliveira, Gustavo Henrique Porto
; Calado, Rafael Vrijdags
; Heimer, Monica Vilela
; Romão, Dayse Andrade
; Pugliesi, Daniela Maria Carvalho
; Santos Junior, Valdeci Elias dos
.
Pesquisa Brasileira em Odontopediatria e Clínica Integrada
- Métricas do periódico
ABSTRACT Objective: To evaluate the influence of non-invasive treatment associated with the use of infiltrating resin for managing caries lesions in primary teeth. Material and Methods: A systematic review was performed by selecting articles from 6 online databases, using a search algorithm and eligibility criteria for data extraction and data synthesis for the papers included. Clinical trials involving primary teeth with incipient caries lesions (1/2 of the enamel or 1/3 of the outer dentin) were included, presenting full text and answering the study's guiding question. This study used the RoB 2 tool for the risk of bias assessment and GRADE for certainty of evidence. Random effects meta-analyses were implemented, and lesion progression treatment effects were estimated through relative risk (RR) and associated 95% confidence intervals. Results: A total of 440 studies were found. After analyzing the inclusion criteria and removal of duplicates, eight studies were analyzed for quality evidence. Five of the eight studies included in this review contributed to the meta-analysis, all with some reflections regarding the risk of bias. Overall, the results of the meta-analysis showed that non-invasive treatment, when associated with the use of infiltrating resins, significantly reduced the risk of caries progression in relation to the treatment without this addition for follow-up periods ranging from 12 months to 2 years (RR 0.51 [0.40-0.65]). Conclusion: There is moderate certainty of evidence that the use of infiltrating resins associated with non-invasive treatments decreases the risk of caries progression in primary teeth with incipient caries lesions (1/2 of the enamel or 1/3 of the dentin outer) when combined with non-invasive control methods alone.
11.
The SISBIOTA-Diptera Brazilian Network: A long-term survey of Diptera from unexplored Brazilian Western Arc of Amazon, Cerrado, and Pantanal
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Lamas, Carlos José Einicker
; Fachin, Diego Aguilar
; Falaschi, Rafaela Lopes
; Alcantara, Daniel Máximo Correa de
; Ale-Rocha, Rosaly
; Amorim, Dalton de Souza
; Araújo, Maíra Xavier
; Ascendino, Sharlene
; Baldassio, Letícia
; Bellodi, Carolina Ferraz
; Bravo, Freddy
; Calhau, Julia
; Capellari, Renato Soares
; Carmo-Neto, Antonio Marcelino do
; Cegolin, Bianca Melo
; Couri, Márcia Souto
; Carvalho, Claudio José Barros de
; Dios, Rodrigo de Vilhena Perez
; Falcon, Aida Vanessa Gomez
; Fusari, Livia Maria
; Garcia, Carolina de Almeida
; Gil-Azevedo, Leonardo Henrique
; Gomes, Marina Morim
; Graciolli, Gustavo
; Gudin, Filipe Macedo
; Henriques, Augusto Loureiro
; Krolow, Tiago Kütter
; Mendes, Luanna Layla
; Limeira-de-Oliveira, Francisco
; Maia, Valéria Cid
; Marinoni, Luciane
; Mello, Ramon Luciano
; Mello-Patiu, Cátia Antunes de
; Morales, Mírian Nunes
; Oliveira, Sarah Siqueira
; Patiu, Claudemir
; Proença, Barbara
; Pujol-Luz, Cristiane Vieira de Assis
; Pujol-Luz, José Roberto
; Rafael, José Albertino
; Riccardi, Paula Raile
; Rodrigues, João Paulo Vinicios
; Roque, Fabio de Oliveira
; Sallum, Maria Anice Mureb
; Santis, Marcelo Domingos de
; Santos, Charles Morphy Dias dos
; Santos, Josenilson Rodrigues dos
; Savaris, Marcoandre
; Shimabukuro, Paloma Helena Fernandes
; Silva, Vera Cristina
; Schelesky-Prado, Daniel de Castro
; Silva-Neto, Alberto Moreira da
; Camargo, Alexssandro
; Sousa, Viviane Rodrigues de
; Urso-Guimarães, Maria Virginia
; Wiedenbrug, Sofia
; Yamaguchi, Carolina
; Nihei, Silvio Shigueo
.
ABSTRACT The SISBIOTA-BRASIL was a three-year multimillion-dollar research program of the Brazilian government to document plants and animals in endangered/understudied areas and biomes in Brazil. Distributional patterns and the historical events that generated them are extensively unknown regarding Brazilian fauna and flora. This deficiency hinders the development of conservation policies and the understanding of evolutionary processes. Conservation decisions depend on precise knowledge of the taxonomy and geographic distribution of species. Given such a premise, we proposed to research the diversity of Diptera of the Brazilian western arc of Amazon, Cerrado, and Pantanal in the states of Mato Grosso, Mato Grosso do Sul, and Rondônia. Three important biomes of the South American continent characterize these Brazilian states: Amazon forest, Cerrado (Brazilian Savannah), and Pantanal. Besides their ecological relevance, these biomes historically lack intensive entomological surveys. Therefore, they are much underrepresented in the Brazilian natural history collections and in the scientific literature, which is further aggravated by the fact that these areas are being exponentially and rapidly converted to commercial lands. Our project involved over 90 collaborators from 24 different Brazilian institutions and one from Colombia among researchers, postdocs, graduate and undergraduate students, and technicians. We processed and analyzed nearly 300,000 specimens from ~60 families of Diptera collected with a large variety of methods in the sampled areas. Here, we provide a detailed overview of the genera and species diversity of 41 families treated. Our results point to a total of 2,130 species and 514 genera compiled and identified for the three states altogether, with an increase of 41% and 29% in the numbers of species and genera known for the three states combined, respectively. Overall, the 10 most species-rich families were Tachinidae, Cecidomyiidae, Tabanidae, Psychodidae, Sarcophagidae, Stratiomyidae, Bombyliidae, Syrphidae, Tephritidae, and Asilidae. The 10 most diverse in the number of genera were Tachinidae, Stratiomyidae, Asilidae, Mycetophilidae, Syrphidae, Tabanidae, Muscidae, Dolichopodidae, Sarcophagidae, and Chloropidae. So far, 111 scientific papers were published regarding taxonomic, phylogenetic, and biogeographical aspects of the studied families, with the description of 101 new species and three new genera. We expect that additional publications will result from this investigation because several specimens are now curated and being researched by specialists.
12.
Brazilian Society of Otology task force - Vestibular Schwannoma - evaluation and treatment
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Silva, Vagner Antonio Rodrigues
; Lavinsky, Joel
; Pauna, Henrique Furlan
; Vianna, Melissa Ferreira
; Santos, Vanessa Mazanek
; Ikino, Cláudio Márcio Yudi
; Sampaio, André Luiz Lopes
; Lopes, Paula Tardim
; Lamounier, Pauliana
; Maranhão, André Souza de Albuquerque
; Soares, Vitor Yamashiro Rocha
; Polanski, José Fernando
; Denaro, Mariana Moreira de Castro
; Chone, Carlos Takahiro
; Bento, Ricardo Ferreira
; Castilho, Arthur Menino
.
Brazilian Journal of Otorhinolaryngology
- Métricas do periódico
Abstract Objective: To review the literature on the diagnosis and treatment of vestibular schwannoma. Methods: Task force members were educated on knowledge synthesis methods, including electronic database search, review and selection of relevant citations, and critical appraisal of selected studies. Articles written in English or Portuguese on vestibular schwannoma were eligible for inclusion. The American College of Physicians’ guideline grading system and the American Thyroid Association’s guideline criteria were used for critical appraisal of evidence and recommendations for therapeutic interventions. Results: The topics were divided into 2 parts: (1) Diagnosis – audiologic, electrophysiologic tests, and imaging; (2) Treatment – wait and scan protocols, surgery, radiosurgery/radiotherapy, and systemic therapy. Conclusions: Decision making in VS treatment has become more challenging. MRI can diagnose increasingly smaller tumors, which has disastrous consequences for the patients and their families. It is important to develop an individualized approach for each case, which highly depends on the experience of each surgical team.
13.
Potential distribution of Amaranthus palmeri under current and future climatic conditions in Brasil and the world
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Ferreira, Sabrina Rodrigues
; Silva, Alexandre Ferreira da
; Silveira, Omar Roberto da
; Santos, José Carlos Barbosa dos
; Batista, Adriene Caldeira
; Araújo, Fausto Henrique Vieira
; Santos, José Barbosa dos
; Silva, Ricardo Siqueira da
.
Abstract Background Amaranthus palmeri is an economically important plant species worldwide. The rapid growth and competitive potential of crops make A. palmeri a major problem. Studies on the dissemination potential of this weed in Brazil and worldwide are necessary to identify the regions with high climatic potential. Similarly, we analyzed the behavior of the species in the face of predicted climate change. Studies of this type can be performed using ecological niche modeling. Objective This work aimed to determine areas with climatic suitability for A. palmeri in the present and future climates in Brazil and globally. Methods We projected the potential distribution of A. palmeri based on the environmental requirements and stress parameters that limit this species in Brazil. Results For the current climate, our model identified regions with favorable climatic suitability for A. palmeri on most continents. The results showed that the suitability of A. palmeri in the Brazilian territory will decrease owing to predicted climate change. The future model highlighted decreases in the suitable northern, northeastern, and midwestern areas. An annual study of the occurrence of A. palmeri using the weekly growth index predicted by the model showed great potential for the species throughout the year, with a decrease in the driest months (July to August), indicating the preference of the species for moist soils. Tropical and subtropical zones are currently experiencing a reduction in suitable areas because of climate change in northeastern Brazil and western Australia. Temperate zone sites have potential areas of expansion for A. palmeri (northern USA, Russia, and China) under climate change. Conclusions Based on the results of this study, management strategies should be planned to contain the global spread of A. palmeri.
14.
[SciELO Preprints] - Guideline of the Brazilian Society of Cardiology on Diagnosis and Treatment of Patients with Chagas Disease Cardiomyopathy
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Marin-Neto, José Antonio
Rassi Jr., Anis
Moraes Oliveira, Gláucia M.
Lemos Correia, Luís Claudio
Novaes Ramos Jr., Alberto
Hasslocher-Moreno, Alejandro Marcel
Luquetti Ostermayer, Alejandro
Sousa, Andréa Silvestre de
Amato Vincenzo de Paola, Angelo
Sobral de Sousa, Antonio Carlos
Pinho Ribeiro, Antonio Luiz
Correia Filho, Dalmo
Moraes de Souza, Dilma do Socorro
Cunha-Neto, Edecio
J. A. Ramires, Felix
Bacal, Fernando
Pereira Nunes, Maria do Carmo
Martinelli Filho, Martino
Ibrahim Scanavacca, Maurício
Magalhães Saraiva, Roberto
Alves de Oliveira Júnior, Wilson
M. Lorga-Filho, Adalberto
de Jesus Benevides de Almeida Guimarães, Adriana
Lopes Latado Braga, Adriana
Sarmento de Oliveira, Adriana
V. L. Sarabanda, Alvaro
Yecê das Neves Pinto, Ana
Assis Lopes do Carmo, André
Schmidt, André
Costa, Andréa Rodrigues da
Ianni, Barbara Maria
Markman Filho, Brivaldo
Eduardo Rochitte, Carlos
Thé Macedo, Carolina
Mady, Charles
Chevillard, Christophe
Bittencourt das Virgens, Cláudio Marcelo
Nery de Castro, Cleudson
De Paoli de Carvalho Britto, Constança Felícia
Pisani, Cristiano
do Carmo Rassi, Daniela
C. Sobral Filho, Dario
Rodrigues Almeida, Dirceu
A. Bocchi, Edimar
T. Mesquita, Evandro
de Souza Nogueira Sardinha Mendes, Fernanda
Pereira, Francisca Tatiana
Sperandio da Silva, Gilberto Marcelo
de Lima Peixoto, Giselle
Glotz de Lima, Gustavo
H. Veloso, Henrique
Turin Moreira, Henrique
Bellotti Lopes, Hugo
Masciarelli Francisco Pinto, Ibraim
Pinto Dias, João Carlos
Bemfica, João Marcos
Silva-Nunes, João Paulo
Soares Barreto-Filho, José Augusto
Kerr Saraiva, José Francisco
Lannes-Vieira, Joseli
Menezes Oliveira, Joselina Luzia
V. Armaganijan, Luciana
Martins, Luiz Cláudio
C. Sangenis, Luiz Henrique
Barbosa, Marco Paulo
Almeida-Santos, Marcos Antônio
Simões, Marcos Vinicius
Shikanai-Yasuda, Maria Aparecida
Vieira Moreira, Maria da Consolação
Higuchi, Maria de Lourdes
Costa Monteiro, Maria Rita de Cássia
Felix Mediano, Mauro Felippe
Maia Lima, Mayara
T. Oliveira, Maykon
Moreira Dias Romano , Minna
Nitz, Nadjar
de Tarso Jorge Medeiros, Paulo
Vieira Alves, Renato
Alkmim Teixeira, Ricardo
Coury Pedrosa, Roberto
Aras, Roque
Morais Torres, Rosália
dos Santos Povoa, Rui Manoel
Rassi, Sérgio Gabriel
Salles Xavier, Sérgio
Marinho Martins Alves , Silvia
B. N. Tavares, Suelene
Lima Palmeira, Swamy
da Silva Junior, Telêmaco Luiz
da Rocha Rodrigues, Thiago
Madrini Junior, Vagner
Maia da Costa , Veruska
Dutra, Walderez
This guideline aimed to update the concepts and formulate the standards of conduct and scientific evidence that support them, regarding the diagnosis and treatment of the Cardiomyopathy of Chagas disease, with special emphasis on the rationality base that supported it.nbsp;
Chagas disease in the 21st century maintains an epidemiological pattern of endemicity in 21 Latin American countries. Researchers and managers from endemic and non-endemic countries point to the need to adopt comprehensive public health policies to effectively control the interhuman transmission of T. cruzi infection, and to obtain an optimized level of care for already infected individuals, focusing on diagnostic and therapeutic opportunistic opportunities.
nbsp;
Pathogenic and pathophysiological mechanisms of the Cardiomyopathy of Chagas disease were revisited after in-depth updating and the notion that necrosis and fibrosis are stimulated by tissue parasitic persistence and adverse immune reaction, as fundamental mechanisms, assisted by autonomic and microvascular disorders, was well established. Some of them have recently formed potential targets of therapies.nbsp;
The natural history of the acute and chronic phases was reviewed, with enhancement for oral transmission, indeterminate form and chronic syndromes. Recent meta-analyses of observational studies have estimated the risk of evolution from acute and indeterminate forms and mortality after chronic cardiomyopathy. Therapeutic approaches applicable to individuals with Indeterminate form of Chagas disease were specifically addressed. All methods to detect structural and/or functional alterations with various cardiac imaging techniques were also reviewed, with recommendations for use in various clinical scenarios. Mortality risk stratification based on the Rassi score, with recent studies of its application, was complemented by methods that detect myocardial fibrosis.nbsp;
The current methodology for etiological diagnosis and the consequent implications of trypanonomic treatment deserved a comprehensive and in-depth approach. Also the treatment of patients at risk or with heart failure, arrhythmias and thromboembolic events, based on pharmacological and complementary resources, received special attention. Additional chapters supported the conducts applicable to several special contexts, including t. cruzi/HIV co-infection, risk during surgeries, in pregnant women, in the reactivation of infection after heart transplantation, and others.nbsp; nbsp;nbsp;
Finally, two chapters of great social significance, addressing the structuring of specialized services to care for individuals with the Cardiomyopathy of Chagas disease, and reviewing the concepts of severe heart disease and its medical-labor implications completed this guideline.
Esta diretriz teve como objetivo principal atualizar os conceitos e formular as normas de conduta e evidências científicas que as suportam, quanto ao diagnóstico e tratamento da CDC, com especial ênfase na base de racionalidade que a embasou.
A DC no século XXI mantém padrão epidemiológico de endemicidade em 21 países da América Latina. Investigadores e gestores de países endêmicos e não endêmicos indigitam a necessidade de se adotarem políticas abrangentes, de saúde pública, para controle eficaz da transmissão inter-humanos da infecção pelo T. cruzi, e obter-se nível otimizado de atendimento aos indivíduos já infectados, com foco em oportunização diagnóstica e terapêutica.
Mecanismos patogênicos e fisiopatológicos da CDC foram revisitados após atualização aprofundada e ficou bem consolidada a noção de que necrose e fibrose sejam estimuladas pela persistência parasitária tissular e reação imune adversa, como mecanismos fundamentais, coadjuvados por distúrbios autonômicos e microvasculares. Alguns deles recentemente constituíram alvos potenciais de terapêuticas.
A história natural das fases aguda e crônica foi revista, com realce para a transmissão oral, a forma indeterminada e as síndromes crônicas. Metanálises recentes de estudos observacionais estimaram o risco de evolução a partir das formas aguda e indeterminada e de mortalidade após instalação da cardiomiopatia crônica. Condutas terapêuticas aplicáveis aos indivíduos com a FIDC foram abordadas especificamente. Todos os métodos para detectar alterações estruturais e/ou funcionais com variadas técnicas de imageamento cardíaco também foram revisados, com recomendações de uso nos vários cenários clínicos. Estratificação de risco de mortalidade fundamentada no escore de Rassi, com estudos recentes de sua aplicação, foi complementada por métodos que detectam fibrose miocárdica.
A metodologia atual para diagnóstico etiológico e as consequentes implicações do tratamento tripanossomicida mereceram enfoque abrangente e aprofundado. Também o tratamento de pacientes em risco ou com insuficiência cardíaca, arritmias e eventos tromboembólicos, baseado em recursos farmacológicos e complementares, recebeu especial atenção. Capítulos suplementares subsidiaram as condutas aplicáveis a diversos contextos especiais, entre eles o da co-infecção por T. cruzi/HIV, risco durante cirurgias, em grávidas, na reativação da infecção após transplante cardíacos, e outros.nbsp;nbsp;nbsp;
Por fim, dois capítulos de grande significado social, abordando a estruturação de serviços especializados para atendimento aos indivíduos com a CDC, e revisando os conceitos de cardiopatia grave e suas implicações médico-trabalhistas completaram esta diretriz.nbsp;
15.
AMPLIFICATION AND SELECTION PROFILE OF ISSR MARKERS FOR GENETIC STUDIES IN Calotropis procera
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DIAS, CIBELLE SANTOS
; SANTOS, LUIZ HENRIQUE TOLENTINO
; MEIRA, MESSULAN RODRIGUES
; SANTOS, ELISA SUSILENE LISBOA DOS
; CERQUEIRA-SILVA, CARLOS BERNARD MORENO
.
RESUMO Algodão de seda é uma espécie vegetal adaptada a vários ecossistemas e tem se destacado pela importância econômica e ecológica. Nós avaliamos o perfil de amplificação de 23 iniciadores ISSR e selecionamos loci polimórficos para estudos genéticos de uma população natural de Calotropis procera por meio da coleta e extração de DNA genômico de 33 indivíduos. O DNA genômico foi extraído usando o protocolo sorbitol e CTAB 2% e os produtos de amplificação ISSR foram resolvidos por eletroforese. Com base no perfil de amplificação, os 23 iniciadores foram classificados como adequados, razoáveis e inadequados. Descrevemos a qualidade dos iniciadores considerando o número total de bandas, média das bandas por iniciador, porcentagem de polimorfismo, diversidade genética de Nei (heterozigosidade esperada - He), assumindo o equilíbrio de Hardy-Weinberg e conteúdo das informações polimórficas (PIC). Todos os iniciadores ISSR apresentaram perfil de amplificação, os quais geraram 173 marcas com média de 7,5 loci por iniciador. Porém, dos 23 iniciadores testados, apenas 18 permitiram amplificação visível e de alta qualidade, que foram classificados como adequado e polimórfico. Também observamos média de 0,30 e 0,24 para as estimativas de PIC e He, respectivamente. Os iniciadores DiCA3`RG, TriAGA3`RC e TriCGC3`RC foram altamente transferíveis para C. procera (apresentaram qualidade para amplificação com boa reprodutibilidade), com valores de PIC superiores a 0,40, He superior a 0,30 e polimorfismo superior a 86%.
ABSTRACT Sodom apple is a plant species adapted to various ecosystems and has stood out for its economic and ecological importance. We evaluated the amplification profile of 23 ISSR primers and selected polymorphic loci for genetic studies of a natural population of Calotropis procera by collecting and extracting genomic DNA from 33 individuals. Genomic DNA was extracted using the sorbitol protocol and 2% CTAB and the ISSR amplification products were resolved by electrophoresis. Based on the amplification profile, the 23 primers were classified as suitable, moderate, and unsuitable. We described the quality of primers considering the total number of bands, mean bands per primer, percentage of polymorphism, Nei’s genetic diversity (expected heterozygosity – He), assuming Hardy-Weinberg equilibrium and the polymorphic information content (PIC). All ISSR primers showed an amplification profile, which generated 173 bands with an average of 7.5 loci per primer. However, only 18 out of the 23 tested primers allowed visible and high-quality amplification, which were classified as suitable and polymorphic. We also observed a mean of 0.30 and 0.24 for PIC and He estimates, respectively. The DiCA3`RG, TriAGA3`RC, and TriCGC3`RC primers were highly transferable to C. procera (they presented quality for amplification with good reproducibility), with PIC values higher than 0.40, He higher than 0.30, and polymorphism higher than 86%.
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