RESUMO Uma das maneiras mais econômicas de construir com solo é a utilização da técnica de adobe. Existem vários tipos de solos e a maioria deles não é adequada para a construção de edifícios. As características físicas e químicas dos solos influenciarão em seu desempenho para uso em construções. Este trabalho tem como objetivo caracterizar fisicamente, quimicamente e mineralogicamente duas amostras de solo e estudar a dosagem de misturas para adobe usando cimento Portland como estabilizador. Foram estudados três diferentes teores de cimento Portland (6%, 9% e 12%) no solo. Os resultados mostraram uma resistência à compressão de até 5 MPa aos 28 dias para os dois tipos de solo estudados com 12% de cimento Portland. Além disso, uma comparação entre dois métodos para a análise do tamanho de partículas dos solos (granulometria) foi realizada. Observou-se que os resultados diferiram em cada método de análise. No geral, este trabalho mostrou que, para usar esses solos em tijolos de adobe, 9% do cimento Portland é suficiente para atingir a resistência à compressão mínima exigida pela norma. Além disso, esta pesquisa traz resultados sobre a determinação do teor de argila do solo por dois métodos. O método tradicional (peneiramento e sedimentação) para determinar a curva de granulométrica pode não ser o mais adequado para verificar o teor de argila contido no solo.

ABSTRACT One of the most economical ways to build with soil is to use adobe technique. There are several types of soils and most of them are not suitable for using to construct buildings. Physical and chemical characteristics of the soils will influence on its performance to use for buildings. This work aims to characterize physically, chemically and mineralogically two soil samples and study the dosage of mixtures for adobe using Portland cement as stabilizer. It was studied three different Portland cement content (6%, 9% and 12%) in the soil. The results showed that compressive strength of up to 5 MPa at 28 days for both type of soils studied with 12% of Portland cement. In addition, a comparison between two methods used for the particle size analysis of the soils. It was observed that the results differed in each method analysis. Overall this work has shown that to use these soils for adobe bricks, 9% of Portland cement is enough to reach the minimum compressive strength required by standard. Furthermore, this research brings results about the determination of the clay content of the soil, indicating that the traditional method to determine the size distribution curve by sieving and sedimentation may not be the most suitable to check this clay content.

BACKGROUND: Bacterial pathogens have many strategies for infecting and persisting in host cells. Adhesion, invasion and intracellular life are important features in the biology of mollicutes. The intracellular location ofUreaplasma diversum may trigger disturbances in the host cell. This includes activation or inhibition of pro and anti-apoptotic factors, which facilitate the development of host damage. The aim of the present study was to associate U. diversum infection in HEp-2 cells and apoptosis induction. Cells were infected for 72hs with four U. diversum clinical isolates and an ATCC strain. The U. diversuminvasion was analyzed by Confocal Laser Scanning Microscopy and gentamicin invasion assay. The apoptosis was evaluated using pro-apoptotic and anti-apoptotic gene expression, and FITC Annexin V/Dead Cell Apoptosis Kit. RESULTS: The number of internalized ureaplasma in HEp-2 cells increased significantly throughout the infection. The flow cytometry analysis with fluorochromes to detect membrane depolarization and gene expression for caspase 2, 3 and 9 increased in infected cells after 24 hours. However, after 72 hours a considerable decrease of apoptotic cells was observed. CONCLUSIONS: The data suggests that apoptosis may be initially induced by some isolates in association with HEp-2 cells, but over time, there was no evidence of apoptosis in the presence of ureaplasma and HEp-2 cells. The initial increase and then decrease in apoptosis could be related to bacterial pathogen-associated molecular pattern (PAMPS). Moreover, the isolates of U. diversum presented differences in the studied parameters for apoptosis. It was also observed that the amount of microorganisms was not proportional to the induction of apoptosis in HEp-2 cells.

O câncer de mama representa o tipo de câncer mais comum em mulheres e constitui a primeira causa de morte por câncer nesta população. As alterações extramamárias relacionadas ao câncer de mama desempenham papel relevante no prognóstico e tratamento desta entidade, sendo fundamental a realização do diagnóstico correto e das diversas alterações. A maioria dessas manifestações é proveniente do tratamento adotado ou de suas complicações e pode estar associada a comprometimento linfonodal, recorrência locorregional ou metástases a distância.

Breast cancer is the most common cancer in women and the leading cause of cancer death among the female population. Extramammary findings related to breast cancer play an important role in the prognosis and treatment of such entity and the correct diagnosis of such alterations is essential for increasing the chance of cure. Most of the times, such manifestations result from complications arising from treatment, and may be associated with lymph node involvement, locoregional recurrence or distant metastasis.