Pesquisa | SciELO

Tucumã (Astrocaryum aculeatum) pulp presents a large number of secondary metabolites that can mediate the synthesis of metallic nanoparticles through a greener and more sustainable synthetic route than traditional ones. This study investigated the production of silver nanoparticles (AgNPs) mediated by aqueous extracts of tucumã pulp assessing different parameters, such as temperature, concentration of extract, and pH values of the reaction media. The alkaline reaction media produced the most intense and well-defined bands around 400 nm in the electronic spectra, indicating the formation of AgNPs in the three concentrations of tucumã pulp evaluated. The increase in the temperature of the reaction media also enhanced the surface plasmon resonance band of AgNPs but it increased the polydispersivity of produced nanoparticles according to the dynamic light scattering (DLS) and transmission electron microscopy (TEM) data. Zeta potential results indicated moderate stability of the AgNPs (close to -30 mV). Antimicrobial assessment of the colloidal metal particles indicated microbicide activity against the Gram-negative Escherichia coli bacterium.

https://doi.org/10.21577/0103-5053.20220141

Clinical characteristics and outcomes of patients with COVID-19 admitted to the intensive care unit during the first and second waves of the pandemic in Brazil: a single-center retrospective cohort study
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Corrêa, Thiago Domingos

; Midega, Thais Dias

; Cordioli, Ricardo Luiz

; Barbas, Carmen Silvia Valente

; Rabello Filho, Roberto

; Silva, Bruno Caldin da

; Silva Júnior, Moacyr

; Nawa, Ricardo Kenji

; Carvalho, Fabrício Rodrigues Torres de

; Matos, Gustavo Faissol Janot de

; Lucinio, Neide Marcela

; Rodrigues, Rodrigo Dias

; Eid, Raquel Afonso Caserta

; Bravim, Bruno de Arruda

; Pereira, Adriano José

; Santos, Bento Fortunato Cardoso dos

; Pinho, João Renato Rebello

; Pardini, Andreia

; Teich, Vanessa Damazio

; Laselva, Claudia Regina

; Cendoroglo Neto, Miguel

; Klajner, Sidney

; Ferraz, Leonardo José Rolim

einstein (São Paulo)

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2023, Volume 21 elocation eAO0233

Resumo: En | Texto: En | PDF: En

ABSTRACT Objective To describe and compare the clinical characteristics and outcomes of patients admitted to intensive care units during the first and second waves of the COVID-19 pandemic. Methods In this retrospective single-center cohort study, data were retrieved from the Epimed Monitor System; all adult patients admitted to the intensive care unit between March 4, 2020, and October 1, 2021, were included in the study. We compared the clinical characteristics and outcomes of patients admitted to the intensive care unit of a quaternary private hospital in São Paulo, Brazil, during the first (May 1, 2020, to August 31, 2020) and second (March 1, 2021, to June 30, 2021) waves of the COVID-19 pandemic. Results In total, 1,427 patients with COVID-19 were admitted to the intensive care unit during the first (421 patients) and second (1,006 patients) waves. Compared with the first wave group [median (IQR)], the second wave group was younger [57 (46-70) versus 67 (52-80) years; p<0.001], had a lower SAPS 3 Score [45 (42-52) versus 49 (43-57); p<0.001], lower SOFA Score on intensive care unit admission [3 (1-6) versus 4 (2-6); p=0.018], lower Charlson Comorbidity Index [0 (0-1) versus 1 (0-2); p<0.001], and were less frequently frail (10.4% versus 18.1%; p<0.001). The second wave group used more noninvasive ventilation (81.3% versus 53.4%; p<0.001) and high-flow nasal cannula (63.2% versus 23.0%; p<0.001) during their intensive care unit stay. The intensive care unit (11.3% versus 10.5%; p=0.696) and in-hospital mortality (12.3% versus 12.1%; p=0.998) rates did not differ between both waves. Conclusion In the first and second waves, patients with severe COVID-19 exhibited similar mortality rates and need for invasive organ support, despite the second wave group being younger and less severely ill at the time of intensive care unit admission.

https://doi.org/10.31744/einstein_journal/2023ao0233

COVID-19 outcomes in people living with HIV: Peering through the waves
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Sales, Thaís Lorenna Souza

; Souza-Silva, Maíra Viana Rego

; Delfino-Pereira, Polianna

; Neves, João Victor Baroni

; Sacioto, Manuela Furtado

; Assis, Vivian Costa Morais de

; Duani, Helena

; Oliveira, Neimy Ramos de

; Sampaio, Natália da Cunha Severino

; Ramos, Lucas Emanuel Ferreira

; Schwarzbold, Alexandre Vargas

; Jorge, Alzira de Oliveira

; Scotton, Ana Luiza Bahia Alves

; Castro, Bruno Mateus de

; Silva, Carla Thais Cândida Alves da

; Ramos, Carolina Marques

; Anschau, Fernando

; Botoni, Fernando Antonio

; Grizende, Genna Maira Santos

; Nascimento, Guilherme Fagundes

; Ruschel, Karen Brasil

; Menezes, Luanna Silva Monteiro

; Castro, Luís César de

; Nasi, Luiz Antônio

; Carneiro, Marcelo

; Godoy, Mariana Frizzo de

; Nogueira, Matheus Carvalho Alves

; Guimarães Júnior, Milton Henriques

; Ziegelmann, Patricia Klarmann

; Almeida, Rafaela Charão de

; Francisco, Saionara Cristina

; Silveira Neto, Sidney Teodoro

; Araújo, Silvia Ferreira

; Avelino-Silva, Thiago Junqueira

; Aliberti, Márlon Juliano Romero

; Pires, Magda Carvalho

; Silva, Eduardo Sérgio da

; Marcolino, Milena Soriano

Clinics

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2023, Volume 78 elocation 100223

Resumo: En | Texto: En | PDF: En

Abstract Objective To evaluate clinical characteristics and outcomes of COVID-19 patients infected with HIV, and to compare with a paired sample without HIV infection. Methods This is a substudy of a Brazilian multicentric cohort that comprised two periods (2020 and 2021). Data was obtained through the retrospective review of medical records. Primary outcomes were admission to the intensive care unit, invasive mechanical ventilation, and death. Patients with HIV and controls were matched for age, sex, number of comorbidities, and hospital of origin using the technique of propensity score matching (up to 4:1). They were compared using the Chi-Square or Fisher's Exact tests for categorical variables and the Wilcoxon for numerical variables. Results Throughout the study, 17,101 COVID-19 patients were hospitalized, and 130 (0.76%) of those were infected with HIV. The median age was 54 (IQR: 43.0;64.0) years in 2020 and 53 (IQR: 46.0;63.5) years in 2021, with a predominance of females in both periods. People Living with HIV (PLHIV) and their controls showed similar prevalence for admission to the ICU and invasive mechanical ventilation requirement in the two periods, with no significant differences. In 2020, in-hospital mortality was higher in the PLHIV compared to the controls (27.9% vs. 17.7%; p = 0.049), but there was no difference in mortality between groups in 2021 (25.0% vs. 25.1%; p > 0.999). Conclusions Our results reiterate that PLHIV were at higher risk of COVID-19 mortality in the early stages of the pandemic, however, this finding did not sustain in 2021, when the mortality rate is similar to the control group.

https://doi.org/10.1016/j.clinsp.2023.100223

Buffered 2% articaine in buccal infiltration of mandibular molars: a randomized triple-blind clinical trial
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LOAYZA, Sandro Alexander Lévano

; BARBIN, Thomas

; SANTOS, Victor Augusto Benedicto dos

; GROPPO, Francisco Carlos

; AMORIM, Klinger de Souza

; PAIVA, Daniel Felipe Fernandes

; FIGUEROBA, Sidney Raimundo

Brazilian Oral Research

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2023, Volume 37 elocation e132

Resumo: En | Texto: En | PDF: En

Abstract This crossover study aimed to compare the anesthetic effects of buffered 2% articaine with 1:200,000 epinephrine with that of non-buffered 4% articaine with 1:200,000 epinephrine. Forty-seven volunteers were administered two doses of anesthesia in the buccal region of the second mandibular molars in two sessions using 1.8 mL of different local anesthetic solutions. The onset time and duration of pulp anesthesia, soft tissue pressure pain threshold, and the score of pain on puncture and burning during injection were evaluated. The operator, volunteers, and statistician were blinded. There were no significant differences in the parameters: onset of soft tissue anesthesia (p = 0.80), duration of soft tissue anesthesia (p = 0.10), onset of pulpal anesthesia in the second (p = 0.28) and first molars (p = 0.45), duration of pulp anesthesia of the second (p = 0.60) and first molars (p = 0.30), pain during puncture (p = 0.82) and injection (p = 0.80). No significant adverse events were observed. Buffered 2% articaine with 1:200,000 epinephrine did not differ from non-buffered 4% articaine with 1:200,000 epinephrine considering anesthetic success, safety, onset, duration of anesthesia, and pain on injection.

https://doi.org/10.1590/1807-3107bor-2023.vol37.0132

Brazilian Thoracic Association recommendations for the management of post-tuberculosis lung disease
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Silva, Denise Rossato

; Santos, Ana Paula

; Visca, Dina

; Bombarda, Sidney

; Dalcolmo, Margareth Maria Pretti

; Galvão, Tatiana

; Miranda, Silvana Spíndola de

; Parente, Ana Alice Amaral Ibiapina

; Rabahi, Marcelo Fouad

; Sales, Roberta Karla Barbosa de

; Migliori, Giovanni Battista

; Mello, Fernanda Carvalho de Queiroz

Jornal Brasileiro de Pneumologia

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2023, Volume 49 Nº 6 elocation e20230269

Resumo: En Pt | Texto: En Pt | PDF: En | PDF: Pt

ABSTRACT Historically, all efforts against tuberculosis were focused on rapid diagnosis and effective treatment to break the chain of transmission of Mycobacterium tuberculosis. However, in the last few years, more and more evidence has been found on the dramatic consequences of the condition defined as post-tuberculosis lung disease (PTLD). Approximately one third of patients surviving pulmonary tuberculosis face considerable ongoing morbidities, including respiratory impairment, psychosocial challenges, and reduced health-related quality of life after treatment completion. Given the important global and local burden of tuberculosis, as well as the estimated burden of PTLD, the development of a consensus document by a Brazilian scientific society-Sociedade Brasileira de Pneumologia e Tisiologia (SBPT)-was considered urgent for the prevention and management of this condition in order to allocate resources to and within tuberculosis services appropriately and serve as a guide for health care professionals. A team of eleven pulmonologists and one methodologist was created by the SBPT to review the current evidence on PTLD and develop recommendations adapted to the Brazilian context. The expert panel selected the topics on the basis of current evidence and international guidelines. During the first phase, three panel members drafted the recommendations, which were divided into three sections: definition and prevalence of PTLD, assessment of PTLD, and management of PTLD. In the second phase, all panel members reviewed, discussed, and revised the recommendations until a consensus was reached. The document was formally approved by the SBPT in a special session organized during the 2023 SBPT Annual Conference.

RESUMO Historicamente, todos os esforços contra a tuberculose concentraram-se no diagnóstico rápido e no tratamento efetivo para quebrar a cadeia de transmissão do Mycobacterium tuberculosis. No entanto, nos últimos anos, têm sido encontradas mais e mais evidências sobre as dramáticas consequências da condição definida como doença pulmonar pós-tuberculose (DPPT). Aproximadamente um terço dos pacientes que sobrevivem à tuberculose pulmonar enfrenta morbidades consideráveis e persistentes, incluindo comprometimento respiratório, desafios psicossociais e redução da qualidade de vida relacionada à saúde após o término do tratamento. Diante da importante carga global e local da tuberculose, bem como da carga estimada da DPPT, considerou-se urgente o desenvolvimento de um documento de consenso por uma sociedade científica brasileira - a Sociedade Brasileira de Pneumologia e Tisiologia (SBPT) - para a prevenção e manejo dessa condição, a fim de alocar recursos de forma adequada para e nos serviços de tuberculose e servir de guia para os profissionais de saúde. Uma equipe de onze pneumologistas e um metodologista foi criada pela SBPT para revisar as evidências atuais sobre a DPPT e desenvolver recomendações adaptadas ao contexto brasileiro. O painel de especialistas selecionou os temas com base nas evidências atuais e diretrizes internacionais. Durante a primeira fase, três membros do painel redigiram as recomendações, que foram divididas em três seções: definição e prevalência de DPPT, avaliação da DPPT e manejo da DPPT. Na segunda fase, todos os membros do painel analisaram, discutiram e revisaram as recomendações até chegar a um consenso. O documento foi aprovado formalmente pela SBPT em sessão especial organizada durante o Congresso Anual da SBPT de 2023.

https://doi.org/10.36416/1806-3756/e20230269

Antioxidant Properties of Croton zehntneri Pax et Hoffm. Essential Oil and Its Inclusion Complex with β-Cyclodextrin Prepared by Spray Drying
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Sousa, Antônio J. P.

; Oliveira, George L. S.

; Fonseca, Lorenna

; Rocha, Marcio S.

; Rai, Mahendra

; Santos, Francisco E. P.

; Lima, Sidney G. de

Journal of the Brazilian Chemical Society

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Out 2022, Volume 33 Nº 10 Páginas 1244 - 1253

Resumo: En | Texto: En | PDF: En

Croton zehntneri Pax et Hoffm. is a plant from Northeastern Brazil, whose main component of its essential oil is estragole. Its thermal instability and low aqueous solubility prevent its technological application. This study aimed to prepare and characterize the Croton zehntneri essential oil (CZEO) complexed with β-cyclodextrin (β-CD), and to evaluate antioxidant activity of free and complexed-CZEO in vitro systems by the elimination of 2,2-diphenyl-1-picrylhydrazyl radicals (DPPH•), 2,2’-azinobis-3-ethylbenzothiazoline-6-sulfonic acid (ABTS•+), hydroxyl and nitric oxide, as well as their ability to transfer electrons by the reducing potential. The infrared spectroscopy and thermal techniques demonstrated the formation of the inclusion complex (Est/β-CD) obtained by spray drying method. The free CZEO and its Est/β-CD at 0.9, 1.8, 3.6, 7.2, 14.4 and 28.8 µg mL-1 showed the ability to remove DPPH• (EC50 (half maximal effective concentration) 26.06 and 9.46 µg mL-1, respectively) and ABTS•+ (EC50 22.73 and 4.47 µg mL-1, respectively), nitric oxide inhibition (EC50 17.65 and 2.68 µg mL-1, respectively), hydroxyl radical sequestration (EC50 23.42 and 2.34 µg mL-1, respectively) and reducing potential (EC50 46.48 and 12.47 µg mL-1, respectively). The formation of the inclusion complex significantly increases its antioxidant potential.

https://doi.org/10.21577/0103-5053.20220051

Occurrence and richness of arbuscular mycorrizal fungi in vineyards with grapevine decline and dieback symptoms
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Bezerra, Aelton dos Santos

; Betancur-Agudelo, Marcelo

; Meyer, Edenilson

; Kemmelmeier, Karl

; Stürmer, Sidney Luiz

; Soares, Cláudio Roberto Fonsêca Sousa

; Lovato, Paulo Emilio

Ciência Rural

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2022, Volume 52 Nº 3 elocation e20210011

Resumo: Pt En | Texto: Pt En | PDF: Pt | PDF: En

RESUMO: Este trabalho teve como objetivo identificar fungos micorrízicos arbusculares (FMA) em solo rizosférico de videiras com sintomas de declínio e morte da videira (D) e em plantas saudáveis (S), e caracterizar a relação das comunidades de FMA com atributos químicos do solo. O número de esporos de FMA variou de 287 a 432 esporos 50 cm-3 em solo em plantas D, e de 357 a 464 esporos 50 cm-3 em plantas S, sem diferenças entre vinhedos ou entre plantas D e S dentro de cada vinhedo. Detectamos 42 espécies e 17 gêneros, sendo que a maioria dos táxons pertencia a Acaulosporaceae ou Glomeraceae. Claroideoglomus etunicatum, Funneliformis mosseae e Archaeospora trappei foram as espécies mais frequentes em todos os vinhedos. Os atributos químicos do solo não foram determinantes para a ocorrência da maioria das espécies de fungos, embora Entrophospora infrequens, Diversispora sp1 e Diversispora sp2 estivessem associados a um vinhedo com alto teor de cobre do solo. Os vinhedos abrigam comunidades FMA altamente diversificadas, que são determinadas pela localização.

ABSTRACT: This research identified arbuscular mycorrhizal fungi (AMF) in rhizosphere soil of grapevines with Grapevine Death and Decline symptoms (GDD) or asymptomatic healthy (H) plants, and characterized the relationship of AMF communities with soil chemical attributes. The AMF spore number ranged from 287 to 432 spores 50 cm-3 in soil with GDD plants, and from 357 to 464 spores 50 cm-3 in H plants, with no differences among vineyards or between GDD and H plants within each vineyard. We detected 42 species and 17 genera, and most taxa belonged to Acaulosporaceae or Glomeraceae. Claroideoglomus etunicatum, Funneliformis mosseae, and Archaeospora trappei were the most frequent species in all vineyards. Soil chemical attributes were not determinant for the occurrence of most fungal species; although, Entrophospora infrequens, Diversispora sp1 and Diversispora sp2 were associated with a vineyard having high soil copper. Vineyards harbor highly diverse AMF communities, which are determined by location.

https://doi.org/10.1590/0103-8478cr20210011 71 downloads

Processing tomato waste as a potential bioactive compounds source: phenolic compounds, antioxidant capacity and bioacessibility studies
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Gomes, Flavia dos Santos

; Silva, Luis Otávio Moreira

; Beres, Carolina

; Pagani, Monica Marques

; Brígida, Ana Iraidy Santa

; Santiago, Manuela Cristina Pessanha de Araújo

; Pacheco, Sidney

; Godoy, Ronoel Luiz de Oliveira

; Cabral, Lourdes Maria Corrêa

Ciência Rural

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2022, Volume 52 Nº 2 elocation e20201070

Resumo: Pt En | Texto: Pt En | PDF: Pt | PDF: En

RESUMO: Foi realizado um estudo comparativo com a extração convencional e assistida por ultrassom em resíduos do processamento de tomate. A extração ultrassônica exibiu teor de fenólicos e flavonóides ligeiramente maiores, bem como maior capacidade antioxidante ABTS + (4,63 mg AG.g-1, 0,96 mg RUE.g-1 e 27,90 μmol TE.g -1, respectivamente). Em ambos os extratos, uma alta porcentagem de flavonóides foi perdida durante a digestão simulada, resultando em uma bioacessibilidade de aproximadamente 13%. Os extratos apresentaram boa estabilidade durante as condições de armazenamento, o que indica uma possível aplicação tecnológica.

ABSTRACT: A comparative study was perfomed with conventional and ultrasound assisted extraction on tomato processing waste. Ultrasound extraction exhibited slightly higher phenolic and flavonoids content, as well as higher ABTS + radical scavenging capacity (4.63 mg GAE.g-1, 0.96 mg RUE.g-1 and 27.90 μmol TE.g -1 respectively). On both extracts, a high percentage of flavonoids was lost during simulated digestion, resulting on a bioacessibility of approximately 13 %. Extracts presented good stability during storage conditions, which indicates a possible technological application.

https://doi.org/10.1590/0103-8478cr20201070 166 downloads

GERMINATION AND POST-SEMINAL DEVELOPMENT OF Astrocaryum murumuru MART. PROGENIES
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Santos, Jucimara Gonçalves dos

; Ferreira, Sidney Alberto do Nascimento

; Gentil, Daniel Felipe de Oliveira

Revista Árvore

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2022, Volume 46 elocation e4629

Resumo: Pt En | Texto: Pt En | PDF: Pt | PDF: En

RESUMO Astrocaryum murumuru é uma palmeira cujas sementes têm sido exploradas extrativamente por populações tradicionais da Amazônia, fornecendo matéria prima à indústria de cosméticos, com carência de informações sobre a sua propagação. Assim, objetivou-se caracterizar a semente, a germinação e o desenvolvimento da plântula de diferentes progênies de A. murumuru. Foram utilizadas sementes de seis racemos de plantas distintas. Essas foram caracterizadas fisicamente e semeadas em delineamento inteiramente ao acaso, com seis tratamentos (progênies) e quatro repetições. Foram feitas a descrição, a ilustração e a quantificação do tempo médio dos diferentes estádios da plântula Em média, o diâmetro, o comprimento e a massa de sementes embebidas foram 17,1 ± 1,2 mm, 28,4 ± 5,8 mm e 3,3 ± 0,6 g, respectivamente. A germinação de A. murumuru é do tipo adjacente, com a bainha cotiledonar se desenvolvendo junto à semente. O desenvolvimento da plântula levou em média 46 ± 28 dias para atingir o estádio de botão germinativo e 225 ± 38 dias para alcançar a fase de terceiro eofilo expandido. A emergência do primeiro catafilo (plântula normal) variou de 12 a 73% entre as progênies, com tempo de médio de 73 ± 29 dias. Observou-se a necessidade de aperfeiçoamento do beneficiamento das sementes de A. murumuru, visando diminuir as perdas de sementes durante o processo, bem como de estudos sobre a dormência das sementes. As progênies apresentaram variação quanto às características físicas e fisiológicas das sementes e plântulas. A germinação e o desenvolvimento da plântula podem ser considerados lentos, com tempo variável entre as progênies.

ABSTRACT Astrocaryum murumuru is a palm tree whose seeds have been exploited in an extractive way by traditional populations in the Amazon, providing raw material to the cosmetic industry, with lack of information about its propagation. Thus, the aim of this study was to characterize seeds, germination, and seedling development of different A murumuru progenies. Seeds from six racemes from different plants were used, which were physically characterized and sown in a completely randomized design, with six treatments (progenies) and four replicates. Description, illustration, and quantification of the mean time of the different seedling stages were performed. On average, the diameter, length, and mass of soaked seeds were 17.1 ± 1.2 mm, 28.4 ± 5.8 mm, and 3.3 ± 0.6 g, respectively. A. murumuru germination is of adjacent type, with the cotyledon sheath developing next to the seed. Seedling development took an average of 46 ± 28 days to reach the germinative bud stage and 225 ± 38 days to reach the third expanded eophyll stage. The emergence of the first cataphyll (normal seedling) ranged from 12 to 73% among progenies, which occurred in an average time of 73 ± 29 days. There is a need to improve the processing of A. murumuru seeds aiming to reduce seed loss during this process, as well as studies on seed dormancy. Progenies showed variation regarding the physical and physiological characteristics of seeds and seedlings. Germination and seedling development can be considered slow, with variable times among progenies.

https://doi.org/10.1590/1806-908820220000029

10.

Narratives of Photographic Records of the Practices of Social Educators of a Residential Group Home for Children and Adolescents
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Ito, Sidney Issao

; Azevêdo, Adriano Valério dos Santos

Paidéia (Ribeirão Preto)

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2022, Volume 32 elocation e3215

Resumo: Pt En Es | Texto: Pt En Es | PDF: Pt | PDF: En | PDF: Es

Resumo O educador social oferece um conjunto de práticas direcionadas para crianças/adolescentes na situação de acolhimento institucional. O presente estudo teve como objetivo analisar as práticas de educadores sociais provenientes das narrativas dos registros fotográficos numa instituição de acolhimento para crianças e adolescentes no Sul do Brasil. Participaram 10 adultos, e utilizou-se a técnica do registro fotográfico e roteiro de entrevista narrativa, que foram analisadas por meio da teoria fundamentada nos dados. O cuidado proporcionado superou a assistência às necessidades básicas, aspecto relevante para práticas realizadas de maneira humanizada e integral. Foram identificadas condições propícias para a expressão do brincar por meio da criatividade, e reconhecimento da história de vida e aspectos do desenvolvimento. Os resultados indicaram envolvimento no cuidado e isto pode fortalecer as estratégias de formação continuada congruentes com as políticas públicas vigentes.

Abstract The social educator offers a set of practices aimed at children/adolescents in institutional care. This study aimed to analyze the practices of social educators based on narratives of photographic records in a residential group homes for children and adolescents in the Southern Brazil. Ten adults participated. Photographic recording and narrative interview script were used and analyzed based on the acquired data. The care provided surpassed the assistance for basic needs, a relevant aspect for practices carried out in a humanized and comprehensive manner. Favorable conditions were identified for the expression of play through creativity, and recognition of life history and aspects of development. The results indicated involvement in care, and this can strengthen continuing education strategies in line with current public policies.

Resumen El educador social cuenta con un conjunto de prácticas dirigidas a niños/adolescentes en acogimiento institucional. El presente estudio tuvo como objetivo analizar las prácticas de los educadores sociales a partir de las narrativas de registros fotográficos en una institución de acogida para niños y adolescentes en el Sur de Brasil. Participaron diez adultos, y se utilizó la técnica de registro fotográfico y guion narrativo de entrevista, la cual fue analizada a partir de la teoría fundamentada en los datos. La atención brindada superó la asistencia a las necesidades básicas, aspecto relevante para las prácticas realizadas de manera humanizada e integral. Se identificaron condiciones favorables para la expresión del juego a través de la creatividad, y el reconocimiento de la historia de vida y aspectos del desarrollo. Los resultados indicaron involucramiento en el cuidado, lo que puede fortalecer estrategias de educación permanente coherentes con las políticas públicas vigentes.

https://doi.org/10.1590/1982-4327e3215

11.

Daily Rainfall Disaggregation to Estimate the Intensity-Duration-Frequency Relationship in Minas Gerais State, Brazil
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Abreu, Marcel Carvalho

; Cecílio, Roberto Avelino

; Pruski, Fernando Falco

; Almeida, Laura Thebit de

; Santos, Gérson Rodrigues dos

; Zanetti, Sidney Sara

; Pereira, Silvio Bueno

; Silva, Demetrius David da

Brazilian Archives of Biology and Technology

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2022, Volume 65 elocation e20210694

Resumo: En | Texto: En | PDF: En

Abstract Sub-daily resolution rain gauge data (pluviographic records) should be used to define extreme rainfall intensity-frequency-duration curves. However, there is a lack of these records for many countries, which leads to the application of rainfall disaggregation models that transforms maximum daily rainfall data into sub-daily depths. The agreement between the intensity-duration-frequency curves obtained with disaggregation models and using sub-daily rainfall data is necessary to support the disaggregation method's applicability. The daily rainfall disaggregation method using disaggregation coefficients is the most used in Brazil, despite the lack of performance evaluation. The linear regression and model identity test was used to compare the intensity of rainfall obtained with different methodologies to obtain intensity-duration-frequency curves in 116 rain gauges in Minas Gerais, Brazil. There is a significant difference between the maximum rainfall intensity (im) obtained from pluviographic records and those estimated by the daily rainfall disaggregation. Nevertheless, comparing the im estimated by the daily rainfall disaggregation methods and the im obtained by sub-daily rainfall data, good precision and accuracy are observed, especially using specific disaggregation coefficients. The disaggregation IDF relationships had an underestimation tendency of im, especially in larger return periods, which can be considered less harmful since the larger return periods are associated with higher safety projects. The practical result of this paper was the possibility of a simple and effective methodology to disaggregate the daily into a sub-daily resolution rainfall.

https://doi.org/10.1590/1678-4324-2022210694

12.

Length-weight relationship of 22 fish species (Osteichthyes) from the surf zone caught by seine net on the northern coast of Pernambuco - Brazil
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Andrade, Sidney

; Dias, Victor

; Bezerra, Natália

; Santos, Lucas

; Coutinho, Isa

; Hazin, Fábio

; Bayse, Shannon

; Oliveira, Paulo

Ocean and Coastal Research

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2022, Volume 70 elocation e22029

Resumo: En | Texto: En | PDF: En

Abstract This study aims to analyze the length-weight relationship (LWR) of 22 fish species collected in the surf zone of Ponta de Pedras, northern coast of Pernambuco, Northeastern Brazil. The specimens were collected between August 2013 and July 2014 using a beach seine net, and their biometry were recorded in laboratory. The LWR was calculated using linear regression and, confidence intervals were estimated for the regression parameters a and b. A total of 1,433 specimens belonging to 22 species, 12 families, and six orders were collected. All species had b values within the expected range of 2.5-3.5 (except for S. plagusia). Additionally, 11 species have hyperallometry, eight have isometry, and three have hypoallometry. Herein, we present values of LWR for Lycengraulis grossidens, Trachinotus goodei, and Umbrina coroides, which are new to Northeastern Brazil, and Albula vulpes and Sparisoma radius which are new for the Brazilian coast.

https://doi.org/10.1590/2675-2824070.21095sa

13.

Lycopene induces bone marrow lymphopoiesis and differentiation of peritoneal IgA-producing cells
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ELIAS, MONIQUE B.

; TEODORO, ANDERSON J.

; LEMOS, FELIPE S.

; BERNARDES, EMERSON S.

; SANTOS, SOFIA N.

; PACHECO, SIDNEY

; OLIVEIRA, FELIPE LEITE DE

Anais da Academia Brasileira de Ciências

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2022, Volume 94 elocation e20210002

Resumo: En | Texto: En | PDF: En

Abstract Lycopene is a hydrocarbon-carotenoid commonly found in red fruits intake with major function correlated to antioxidative capacity in several pathological conditions, including cancer and cardiovascular diseases. Recently, lycopene has been associated with hematopoiesis, although the effects on B lymphocyte differentiation and antibody production are poorly understood. In this work, the principal aim was to investigate whether lycopene affects B lymphopoiesis and terminal differentiation into plasma cells. Distinct in vivo and in vitro strategies based on lycopene supplementation were used direct in Balb/c mice or in culture systems with cells derived of these mice. In the bone marrow, lycopene expanded B220+IgM- progenitor B cells and B220+IgM+ immature B lymphocytes. In the spleen, lycopene induced terminal CD138+ plasma cell generation. In the blood, we found prominent IgA and low IgM levels after lycopene administration. Interestingly, the pattern of peritoneal IgM+ and IgA+ B cells indicated a significant IgM-to-IgA class switching after lycopene injection. These data indicated that lycopene induces B cell differentiation into IgA-producing plasma cells. Thus, a new cellular function has been attributed to lycopene for B lymphocyte biology and possibly associated with humoral responses and mucosal immunity.

https://doi.org/10.1590/0001-3765202220210002

14.

Mortalidade por Insuficiência Cardíaca durante a Pandemia da COVID-19: Insights de uma Coorte de Hospitais Públicos no Brasil
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Fernandes-Silva, Miguel M.

; Adam, Eduardo Leal

; Bernardez-Pereira, Sabrina

; Silva, Suzana Alves

; Passaglia, Luiz Guilherme

; Pereira, Kleber Renato Ponzi

; Guedes, Marco Antônio Vieira

; Souza Neto, João David de

; Paola, Ângelo Amato Vincenzo de

; Rivera, Maria Alayde Mendonça

; Resende, Elmiro Santos

; Albuquerque, Denilson Campos de

; Bacal, Fernando

; Ribeiro, Antônio Luiz Pinho

; Morgan, Louise

; Smith Jr, Sidney C.

; Taniguchi, Fábio Papa

Arquivos Brasileiros de Cardiologia

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2022, Nº ahead

Resumo: Pt En | Texto: Pt En | PDF: Pt | PDF: En

https://doi.org/10.36660/abc.20220080

15.

Recommendations by the Scientific Department of Neuroimmunology of the Brazilian Academy of Neurology (DCNI/ABN) and the Brazilian Committee for Treatment and Research in Multiple Sclerosis and Neuroimmunological Diseases (BCTRIMS) on vaccination in general and specifically against SARS-CoV-2 for patients with demyelinating diseases of the central nervous system
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Becker, Jefferson

; Ferreira, Lis Campos

; Damasceno, Alfredo

; Bichuetti, Denis Bernardi

; Christo, Paulo Pereira

; Callegaro, Dagoberto

; Peixoto, Marco Aurélio Lana

; Sousa, Nise Alessandra De Carvalho

; Almeida, Sérgio Monteiro De

; Adoni, Tarso

; Santiago-Amaral, Juliana

; Junqueira, Thiago

; Pereira, Samira Luisa Apóstolos

; Gomes, Ana Beatriz Ayroza Galvão Ribeiro

; Pitombeira, Milena

; Paolilo, Renata Barbosa

; Grzesiuk, Anderson Kuntz

; Piccolo, Ana Claudia

; D´Almeida, José Arthur Costa

; Gomes Neto, Antonio Pereira

; Oliveira, Augusto Cesar Penalva De

; Oliveira, Bianca Santos De

; Tauil, Carlos Bernardo

; Vasconcelos, Claudia Ferreira

; Kaimen-Maciel, Damacio

; Varela, Daniel

; Diniz, Denise Sisterolli

; Oliveira, Enedina Maria Lobato De

; Malfetano, Fabiola Rachid

; Borges, Fernando Elias

; Figueira, Fernando Faria Andrade

; Gondim, Francisco De Assis Aquino

; Passos, Giordani Rodrigues Dos

; Silva, Guilherme Diogo

; Olival, Guilherme Sciascia Do

; Santos, Gutemberg Augusto Cruz Dos

; Ruocco, Heloisa Helena

; Sato, Henry Koiti

; Soares Neto, Herval Ribeiro

; Cortoni Calia, Leandro

; Gonçalves, Marcus Vinícius Magno

; Vecino, Maria Cecilia Aragón De

; Pimentel, Maria Lucia Vellutini

; Ribeiro, Marlise De Castro

; Boaventura, Mateus

; Parolin, Mônica Koncke Fiuza

; Melo, Renata Brant De Souza

; Lázaro, Robson

; Thomaz, Rodrigo Barbosa

; Kleinpaul, Rodrigo

; Dias, Ronaldo Maciel

; Gomes, Sidney

; Lucatto, Simone Abrante

; Alves-Leon, Soniza Vieira

; Fukuda, Thiago

; Ribeiro, Taysa Alexandrino Gonsalves Jubé

; Winckler, Thereza Cristina D’ávila

; Fragoso, Yara Dadalti

; Nascimento, Osvaldo José Moreira Do

; Ferreira, Maria Lucia Brito

; Mendes, Maria Fernanda

; Brum, Doralina Guimarães

; Glehn, Felipe Von

Arquivos de Neuro-Psiquiatria

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Nov 2021, Volume 79 Nº 11 Páginas 1049 - 1061

Resumo: Pt En | Texto: Pt En | PDF: Pt | PDF: En

RESUMO O DC de Neuroimunologia da ABN e o BCTRIMS trazem, nesse documento, as recomendações sobre vacinação da população com doenças desmielinizantes do sistema nervoso central (SNC) contra infecções em geral e contra o coronavírus da síndrome respiratória aguda grave 2 (SARS-CoV-2), causador da COVID-19. Destaca-se a gravidade do atual momento frente ao avanço da COVID-19 em nosso País, o que torna mais evidente e importante a criação de guia de referência para orientação aos médicos, pacientes e autoridades de saúde pública quanto à vacinação, meio efetivo e seguro no controle de determinadas doenças infecciosa. O DCNI/ABN e o BCTRIMS recomendam que os pacientes com doenças desmielinizantes do SNC (ex., EM e NMOSD) sejam constantemente monitorados, quanto a atualização do seu calendário vacinal, especialmente, no início ou antes da mudança do tratamento com uma droga modificadora de doença (DMD). É importante também salientar que as vacinas são seguras e os médicos devem estimular o seu uso em todos os pacientes. Evidentemente, deve ser dada especial atenção às vacinas com vírus vivos atenuados. Por fim, é importante que os médicos verifiquem qual DMD o paciente está em uso e quando foi feita a sua última dose, pois cada fármaco pode interagir de forma diferente com a indução da resposta imune.

ABSTRACT The Scientific Department of Neuroimmunology of the Brazilian Academy of Neurology (DCNI/ABN) and Brazilian Committee for Treatment and Research in Multiple Sclerosis and Neuroimmunological Diseases (BCTRIMS) provide recommendations in this document for vaccination of the population with demyelinating diseases of the central nervous system (CNS) against infections in general and against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which causes COVID-19. We emphasize the seriousness of the current situation in view of the spread of COVID-19 in our country. Therefore, reference guides on vaccination for clinicians, patients, and public health authorities are particularly important to prevent some infectious diseases. The DCNI/ABN and BCTRIMS recommend that patients with CNS demyelinating diseases (e.g., MS and NMOSD) be continually monitored for updates to their vaccination schedule, especially at the beginning or before a change in treatment with a disease modifying drug (DMD). It is also important to note that vaccines are safe, and physicians should encourage their use in all patients. Clearly, special care should be taken when live attenuated viruses are involved. Finally, it is important for physicians to verify which DMD the patient is receiving and when the last dose was taken, as each drug may affect the induction of immune response differently.

https://doi.org/10.1590/0004-282x-anp-2021-0162 1 downloads

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