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ABSTRACT Handball is characterised by rapid transitions between offensive and defensive actions during the game in order to score goals. The level of declarative tactical knowledge (DTC) and physical fitness (FPA) of the athlete can influence performance. This study aimed to analyse the correlation between the level of CTD and APF of handball athletes. The sample population involved 16 athletes aged 16.69 (± 0.60) years, male, chosen by convenience. We used the Sport Brazil Project and CTD protocols. The body mass index of the analysed group had an average of 24.05 (± 5.71), indicating eutrophy and the waist-to-height ratio had an average of 0.82 (± 0.13), a healthy zone. Regarding the fitness level of the athletes, we identified weak levels for agility (100%), very good for flexibility (62.5%), good for lower limbs strength (62.5%), very good for upper limbs strength (50%), good for cardiorespiratory resistance (68.8%), reasonable for localised muscle resistance (37.5%) and weak for speed (100%). The CTD level was poor and evolving with a mean of 2.50 (± 1.03). The components of APF and CTD did not show significant correlations. Furthermore, the results were promising; however, they are below the standards of excellence, requiring improvement.

RESUMO O handebol caracteriza-se por transições rápidas entre ações ofensivas e defensivas durante o jogo com objetivo de marcar gols. O nível de conhecimento tático declarativo (CTD) e de aptidão física (APF) do atleta pode influenciar o desempenho. Este estudo objetivou-se em analisar a correlação entre o nível de CTD e de APF de atletas de handebol. A população amostra envolveu 16 atletas, com idade de 16,69 (± 0,60) anos, sexo masculino, escolhidos por conveniência. Utilizamos os protocolos do Projeto Esporte Brasil e CTD. O índice de massa corporal do grupo analisado apresentou média de 24,05 (± 5,71), apontando eutrofia e a relação cintura e média de estatura foi de 0,82 (± 0,13), zona saudável. Em relação à APF dos atletas, identificamos níveis fraco para agilidade (100%), muito bom para flexibilidade (62,5%), bom para força de membros inferiores, (62,5%) muito bom para força de membros superiores (50%), bom para resistência cardiorrespiratória (68,8%), razoável para resistência muscular localizada (37,5%) e fraco para velocidade (100%). O nível de CTD apresentou nível fraco e em evolução com média de 2,50 (± 1,03). Os componentes da APF e CTD não apresentaram correlações significativas. Ademais, os resultados foram promissores, porém, estão aquém dos padrões de excelência, necessitando melhorias.

https://doi.org/10.6063/motricidade.30736

Fortalecimento da governança regional e da rede de atenção à saúde em municípios pequenos no Brasil
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Silva, João Felipe Marques da

; Pantaleão, Cristiane Martins

; Santos, Clodoaldo Fernandes dos

; Leles, Fernando Antônio Gomes

; Rocha, Karen Patrícia Wilke Pereira

; Giacometti, Luana Carla Tironi de Freitas

; Terabe, Sandro Haruyuki

; Galiano, Socorro Gross

; Neto, Valdeni Alexandre Ciconello

Revista Panamericana de Salud Pública

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2023, Volume 47 elocation e120

Resumo: Pt Es En | Texto: Pt Es En | PDF: Pt | PDF: Es | PDF: En

RESUMO No Brasil, 67,7% dos municípios têm menos de 20 mil habitantes, sendo caracterizados como de pequeno porte. O objetivo do presente artigo é sistematizar a experiência e identificar os desafios e as lições aprendidas na implantação do modelo de fortalecimento da governança regional e da organização da rede de atenção à saúde (RAS) em uma região do Brasil composta por esses municípios, que apresentam baixa capacidade técnica e orçamentária, além de fragilidades diversas relacionadas à organização da RAS. Na perspectiva do fortalecimento da governança regional e da organização do processo de trabalho da atenção primária em saúde (APS) e, por consequência, dos fluxos com os outros níveis de atenção, foi proposta a estratégia intitulada Mais Cuidado Mais Saúde, desenvolvida em parceria com a Organização Pan-Americana da Saúde/Organização Mundial da Saúde (OPAS/OMS) e o Ministério da Saúde. O projeto foi executado por meio de processos de educação permanente em saúde e fortalecimento de capacidades institucionais na região de Ivaiporã/Paraná, com oficinas descentralizadas, contemplando três eixos prioritários: integração da RAS, formação de capacidades e gestão da informação. O público-alvo foram as equipes de APS ampliada. O projeto permitiu desenvolver capacidades locais e de governança regional por meio de reflexões conjuntas a respeito do modelo de atenção à saúde, de seus componentes e das mudanças necessárias nos processos de trabalho para a promoção de saúde com foco na qualidade de vida dos usuários. Por se tratar de uma experiência que considera as fragilidades, necessidades e autonomia dos atores locais, o projeto tem alto poder de replicação e customização para outras regiões com características similares dentro e fora do Brasil.

RESUMEN En Brasil, 67,7% de los municipios se clasifican como pequeños, puesto que tienen menos de 20 000 habitantes. El objetivo de este artículo es sistematizar la experiencia adquirida y determinar cuáles son los desafíos y las enseñanzas extraídas en la implementación del modelo de fortalecimiento de la gobernanza regional y de la organización de la red de atención de salud en una región de Brasil compuesta por municipios de este tipo, que tienen poca capacidad técnica y presupuestaria y diversas debilidades relacionadas con la organización de dicha red. Desde la perspectiva del fortalecimiento de la gobernanza regional y de la organización del proceso de trabajo en el campo de la atención primaria de salud y, por consiguiente, de los flujos asistenciales con los demás niveles de atención, se propuso la estrategia Más cuidado, más salud, formulada junto con la Organización Panamericana de la Salud/Organización Mundial de la Salud (OPS/OMS) y el Ministerio de Salud. El proyecto se ejecutó por medio de procesos de educación permanente en salud y fortalecimiento de las capacidades institucionales en la región de Ivaiporã, Estado de Paraná, con talleres descentralizados, dentro de tres ejes prioritarios, a saber, integración de red de atención de salud, capacitación y gestión de la información. El público destinatario fueron los equipos de atención primaria de salud ampliada. El proyecto permitió el desarrollo de las capacidades locales y la gobernanza regional por medio de reflexiones conjuntas sobre el modelo de atención de salud, sus elementos constitutivos y los cambios necesarios en los procesos de trabajo para impulsar la promoción de la salud centrada en la calidad de vida de los usuarios. Por tratarse de una experiencia en la cual se tienen en cuenta las debilidades, las necesidades y la autonomía de los actores locales, el proyecto tiene un alto poder de repetición y adaptación en otras regiones con características similares dentro y fuera de Brasil.

ABSTRACT In Brazil, 67.7% of the municipalities are characterized as small, with a population of less than 20 thousand. The objective of this article is to systematize the experience and identify the challenges and lessons learned in the implementation of the model for strengthening regional governance and organizing the health care network (HCN) in a region of Brazil composed of these municipalities, which present low technical and budgetary capacity, in addition to various fragilities related to the organization of the HCN. With a view to strengthening regional governance and the organization of the primary health care (PHC) work process and, consequently, the workflow with other levels of care, a strategy entitled More Care More Health (Mais Cuidado Mais Saúde) was proposed, developed in partnership with the Pan American Health Organization/World Health Organization (PAHO/WHO) and the Ministry of Health. The project was developed through permanent health education and institutional capacity building in the region of Ivaiporã, state of Paraná, based on workshops and addressing three priority axes: HCN integration, capacity building and information management. The target audience were the extended PHC teams. The project made it possible to develop local and governance capacities through joint reflections on the health care model, its components and the necessary changes in work processes for health promotion with a focus on the quality of life of users. Because it is an experience that considers the weaknesses, needs and autonomy of local actors, the project has a high potential for replication and customization for other regions with similar characteristics inside and outside Brazil.

https://doi.org/10.26633/rpsp.2023.120

Differentially methylated regions identified in bovine embryos are not observed in adulthood
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Vargas, Luna Nascimento

; Nochi, Allice Rodrigues Ferreira

; Castro, Paloma Soares de

; Cunha, Andrielle Thainar Mendes

; Silva, Thainara Christie Ferreira

; Togawa, Roberto Coiti

; Silveira, Márcia Marques

; Caetano, Alexandre Rodrigues

; Franco, Maurício Machaim

Animal Reproduction

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2023, Volume 20 Nº 1 elocation e20220076

Resumo: En | Texto: En | PDF: En

Abstract The establishment of epigenetic marks during the reprogramming window is susceptible to environmental influences, and stimuli during this critical stage can cause altered DNA methylation in offspring. In a previous study, we found that low levels of sulphur and cobalt (low S/Co) in the diet offered to oocyte donors altered the DNA methylome of bovine embryos. However, due to the extensive epigenetic reprogramming that occurs during embryogenesis, we hypothesized that the different methylation regions (DMRs) identified in the blastocysts may not maintain in adulthood. Here, we aimed to characterize DMRs previously identified in embryos, in the blood and sperm of adult progenies of two groups of heifers (low S/Co and control). We used six bulls and characterized the DNA methylation levels of KDM2A, KDM5A, KMT2D, and DOT1L genes. Our results showed that all DMRs analysed in both groups and tissues were hypermethylated unlike that noticed in the embryonic methylome profiles. These results suggest that embryo DMRs were reprogrammed during the final stages of de novo methylation during embryogenesis or later in development. Therefore, due to the highly dynamic epigenetic state during early embryonic development, we suggest that is essential to validate the DMRs found in embryos in adult individuals.

https://doi.org/10.1590/1984-3143-ar2022-0076

COVID-19 outcomes in people living with HIV: Peering through the waves
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Sales, Thaís Lorenna Souza

; Souza-Silva, Maíra Viana Rego

; Delfino-Pereira, Polianna

; Neves, João Victor Baroni

; Sacioto, Manuela Furtado

; Assis, Vivian Costa Morais de

; Duani, Helena

; Oliveira, Neimy Ramos de

; Sampaio, Natália da Cunha Severino

; Ramos, Lucas Emanuel Ferreira

; Schwarzbold, Alexandre Vargas

; Jorge, Alzira de Oliveira

; Scotton, Ana Luiza Bahia Alves

; Castro, Bruno Mateus de

; Silva, Carla Thais Cândida Alves da

; Ramos, Carolina Marques

; Anschau, Fernando

; Botoni, Fernando Antonio

; Grizende, Genna Maira Santos

; Nascimento, Guilherme Fagundes

; Ruschel, Karen Brasil

; Menezes, Luanna Silva Monteiro

; Castro, Luís César de

; Nasi, Luiz Antônio

; Carneiro, Marcelo

; Godoy, Mariana Frizzo de

; Nogueira, Matheus Carvalho Alves

; Guimarães Júnior, Milton Henriques

; Ziegelmann, Patricia Klarmann

; Almeida, Rafaela Charão de

; Francisco, Saionara Cristina

; Silveira Neto, Sidney Teodoro

; Araújo, Silvia Ferreira

; Avelino-Silva, Thiago Junqueira

; Aliberti, Márlon Juliano Romero

; Pires, Magda Carvalho

; Silva, Eduardo Sérgio da

; Marcolino, Milena Soriano

Clinics

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2023, Volume 78 elocation 100223

Resumo: En | Texto: En | PDF: En

Abstract Objective To evaluate clinical characteristics and outcomes of COVID-19 patients infected with HIV, and to compare with a paired sample without HIV infection. Methods This is a substudy of a Brazilian multicentric cohort that comprised two periods (2020 and 2021). Data was obtained through the retrospective review of medical records. Primary outcomes were admission to the intensive care unit, invasive mechanical ventilation, and death. Patients with HIV and controls were matched for age, sex, number of comorbidities, and hospital of origin using the technique of propensity score matching (up to 4:1). They were compared using the Chi-Square or Fisher's Exact tests for categorical variables and the Wilcoxon for numerical variables. Results Throughout the study, 17,101 COVID-19 patients were hospitalized, and 130 (0.76%) of those were infected with HIV. The median age was 54 (IQR: 43.0;64.0) years in 2020 and 53 (IQR: 46.0;63.5) years in 2021, with a predominance of females in both periods. People Living with HIV (PLHIV) and their controls showed similar prevalence for admission to the ICU and invasive mechanical ventilation requirement in the two periods, with no significant differences. In 2020, in-hospital mortality was higher in the PLHIV compared to the controls (27.9% vs. 17.7%; p = 0.049), but there was no difference in mortality between groups in 2021 (25.0% vs. 25.1%; p > 0.999). Conclusions Our results reiterate that PLHIV were at higher risk of COVID-19 mortality in the early stages of the pandemic, however, this finding did not sustain in 2021, when the mortality rate is similar to the control group.

https://doi.org/10.1016/j.clinsp.2023.100223

Physiological maturation of sweet sorghum seeds produced under water restriction
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Silva, Weslley Costa

; Moura, Joana Gomes de

; Oliveira, Alexandre Bosco de

; Batista, Maria Susana Silva

; Brito, Leonardo Lenin Marques de

; Sousa, Kleyton Chagas de

Revista Ciência Agronômica

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2023, Volume 54 elocation e20217942

Resumo: En | Texto: En | PDF: En

ABSTRACT Sweet sorghum has been shown to be an alternative for ethanol production in several regions. Because it is sexually propagated, the use of quality seeds becomes an important factor for obtaining an adequate plant stand and, consequently, good productivity. Thus, the objective was to evaluate the production and physiological maturation of seeds of sweet sorghum cv. BRS 511, in response to the interval between irrigations during the reproductive period and harvesting period. Two experiments were carried out in a greenhouse, the experimental design adopted was in randomized blocks, with four replications in a 3 x 2 split-plot scheme, corresponding to three intervals between irrigations during the reproductive stage (0; 4 and 8 days) and two harvest times (102 and 110 days after sowing). The following parameters were evaluated from the harvested panicles: number of seeds, weight of one thousand seeds, water content, germination, first germination count, emergence in sand and emergence speed, electrical conductivity and seedling vigor. The production of seeds per panicle and the weight of a thousand seeds were significantly influenced by the increase in the interval between irrigations in the 2nd experiment, with a reduction of 50.4 and 46.3%, respectively. Water replacement every eight days caused a reduction of up to 43.4% in the first germination count and 16.3% in germination. The production and quality of sweet sorghum seeds reduces as a function of the increase in the interval between irrigations and the harvesting time, presenting germination rates below the required for commercialization.

https://doi.org/10.5935/1806-6690.20230053

Posicionamento sobre a Saúde Cardiovascular nas Mulheres – 2022
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Oliveira, Glaucia Maria Moraes de

; Almeida, Maria Cristina Costa de

; Marques-Santos, Celi

; Costa, Maria Elizabeth Navegantes Caetano

; Carvalho, Regina Coeli Marques de

; Freire, Cláudia Maria Vilas

; Magalhães, Lucelia Batista Neves Cunha

; Hajjar, Ludhmila Abrahão

; Rivera, Maria Alayde Mendonça

; Castro, Marildes Luiza de

; Avila, Walkiria Samuel

; Lucena, Alexandre Jorge Gomes de

; Brandão, Andréa Araujo

; Macedo, Ariane Vieira Scarlatelli

; Lantieri, Carla Janice Baister

; Polanczyk, Carisi Anne

; Albuquerque, Carlos Japhet da Matta

; Born, Daniel

; Falcheto, Eduardo Belisário

; Bragança, Érika Olivier Vilela

; Braga, Fabiana Goulart Marcondes

; Colombo, Fernanda M. Consolim

; Jatene, Ieda Biscegli

; Costa, Isabela Bispo Santos da Silva

; Rivera, Ivan Romero

; Scholz, Jaqueline Ribeiro

; Melo Filho, José Xavier de

; Santos, Magaly Arrais dos

; Izar, Maria Cristina de Oliveira

; Azevedo, Maria Fátima

; Moura, Maria Sanali

; Campos, Milena dos Santos Barros

; Souza, Olga Ferreira de

; Medeiros, Orlando Otávio de

; Silva, Sheyla Cristina Tonheiro Ferro da

; Rizk, Stéphanie Itala

; Rodrigues, Thais de Carvalho Vieira

; Salim, Thaís Rocha

; Lemke, Viviana de Mello Guzzo

Arquivos Brasileiros de Cardiologia

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Nov 2022, Volume 119 Nº 5 Páginas 815 - 882

Resumo: Pt En | Texto: Pt En | PDF: Pt | PDF: En

https://doi.org/10.36660/abc.20220734

Establishment of tropical forage grasses in the Cerrado biome
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Gurgel, Antonio Leandro Chaves

; Difante, Gelson dos Santos

; Costa, Carolina Marques

; Emerenciano Neto, João Virgínio

; Tonhão, Gustavo Henrique

; Ítavo, Luís Carlos Vinhas

; Dias, Alexandre Menezes

; Vilela, Iuri Mesquita Moraes

; Oliveira, Vivian Garcia de

; Lima, Pâmella Cristina da Silva

; Miyake, Andrey William Alce

Revista mexicana de ciencias pecuarias

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Set 2022, Volume 13 Nº 3 Páginas 674 - 689

Resumo: En Es | Texto: En Es | PDF: En | PDF: Es

Abstract This study was carried out to evaluate the time for the establishment of tropical forage grasses in the “Cerrado” biome, based on morphogenetic and structural traits. Three Brachiaria brizantha (Syn. Urochloa brizantha) cultivars (Paiaguás, Ipyporã and Marandu) and two Panicum maximum (Syn. Megathyrsus maximus) cultivars (Quênia and Tamani) were distributed in a randomized-block design with four replicates. Morphogenetic and structural traits of the pasture were assessed from d 35 to d 65 after sowing, at seven-day interval. Canopy height rose linearly with the establishment period, in all cultivars. In the Megathyrsus cultivars, tiller density decreased as the experimental period progressed, whereas the number of tillers in the Urochloa cultivars increased. The cultivars Ipyporã and Marandu had the highest leaf appearance rates. The lowest leaf elongation rates occurred in the cultivars Paiaguás, Ipyporã and Tamani, and the highest elongation rates in cv. Quênia. As a result, cv. Quênia showed the highest values of final leaf length (64.9 cm) and leaf blade mass (3,352.9 kg DM ha-1). The higher senescence rate of cv. Tamani (2.1 cm tiller-1 d-1) resulted in the highest percentage of dead material (1,815.5 kg ha-1) being found in the herbage mass of this cultivar. Cultivars Paiaguás, Marandu and Tamani were established at 44 d, whereas cv. Quênia and Ipyporã were established at 51 and 58 d after sowing, respectively, in the Brazilian Cerrado.

Resumen Este estudio se llevó a cabo para evaluar el tiempo para el establecimiento de gramíneas forrajeras tropicales en el bioma del “Cerrado”, con base en rasgos morfogenéticos y estructurales. Se distribuyeron tres cultivares (Paiaguás, Ipyporã y Marandu) de Brachiaria brizantha (Sin. Urochloa brizantha) y dos cultivares (Quênia y Tamani) de Panicum maximum (Sin. Megathyrsus maximus) en un diseño de bloques al azar con cuatro repeticiones. Los rasgos morfogenéticos y estructurales del pasto se evaluaron desde el día 35 hasta el día 65 después de la siembra, a intervalos de siete días. La altura del dosel aumentó linealmente con el período de establecimiento, en todos los cultivares. En los cultivares de Megathyrsus, la densidad de macollos disminuyó a medida que avanzaba el período experimental, mientras que el número de macollos en los cultivares de Urochloa aumentó. Los cultivares Ipyporã y Marandu tuvieron las tasas más altas de aparición foliar. Las tasas de elongación foliar más bajas se presentaron en los cultivares Paiaguás, Ipyporã y Tamani, y las tasas de elongación más altas en el cv. Quênia. Como resultado, el cv. Quênia mostró los valores más altos de longitud foliar final (64.9 cm) y masa de lámina foliar (3,352.9 kg MS ha-1). La mayor tasa de senescencia del cv. Tamani (2.1 cm macollo-1 d-1) dio como resultado que el mayor porcentaje de material muerto (1,815.5 kg ha-1) se encontrara en la masa de forraje de este cultivar. Los cultivares Paiaguás, Marandu y Tamani se establecieron a los 44 d, mientras que los cv. Quênia e Ipyporã se establecieron a los 51 y 58 días después de la siembra, respectivamente, en el Cerrado brasileño.

https://doi.org/10.22319/rmcp.v13i3.6039 17 downloads

The mental health of Brazilian healthcare professionals during the COVID-19 pandemic: a longitudinal study
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Serpa, Alexandre Luiz de Oliveira

; Pinto, André Luiz Braule

; Diaz, Alexandre Paim

; Romano-Silva, Marco Aurélio

; Costa, Danielle de Souza

; Joaquim, Rui M.

; de Paula, Jonas Jardim

; Guatimosim, Rafaela

; da Silva, Antônio Geraldo

; de Miranda, Débora Marques

; Malloy-Diniz, Leandro F.

Brazilian Journal of Psychiatry

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Ago 2022, Volume 44 Nº 4 Páginas 401 - 408

Resumo: En | Texto: En | PDF: En

Objective: To compare the distress level among Brazilian healthcare professionals during the coronavirus disease 2019 (COVID-19) pandemic and estimate risks by sex, age, and occupation. Methods: In a longitudinal cohort design, a nationally distributed online survey was used to collect data from 10,490 active healthcare professionals who worked during the pandemic. Participants were mostly female, aged 18 to 82 years; 13 different health professions and all states of Brazil were represented. Results: The most frequent professions were psychology, dentistry, and nursing. The Brief Symptom Inventory (BSI) score suggested an increased distress perception among health professionals. Females showed poorer mental health than males, but the absolute rise in Global Severity Index (GSI) score was larger in males than in females. Younger adults reported more symptoms of psychological distress than older adults. The most impacted age group was between 30-39 years. Nurse technicians presented the highest risk of distress. Conclusion: Health professionals are essential to overcoming the pandemic; thus, their mental health status should be monitored, and features associated with increased distress should be identified. Our findings suggest distress risk should be stratified by occupation, age, and sex. Health professionals showed an increased distress perception. Women, individuals between the ages of 30 and 39, nursing personnel, and physicians were more likely to report distress compared with other health professionals.

https://doi.org/10.47626/1516-4446-2021-2347

Reducing care time after implementing protocols for acute ischemic stroke: a systematic review
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Leite, Karina Fonseca de Souza

; Santos, Samuel Ribeiro dos

; Andrade, Rubia Laine de Paula

; Faria, Mariana Gaspar Botelho Funari de

; Saita, Nanci Michele

; Arcêncio, Ricardo Alexandre

; Isaac, Igor Simões da Silva

; Rezende, Carlos Eduardo Menezes de

; Villa, Tereza Cristina Scatena

; Pontes Neto, Octavio Marques

; Monroe, Aline Aparecida

Arquivos de Neuro-Psiquiatria

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Jul 2022, Volume 80 Nº 7 Páginas 725 - 740

Resumo: En Pt | Texto: En Pt | PDF: En | PDF: Pt

Abstract Background The treatment of acute ischemic stroke with cerebral reperfusion therapy requires rapid care and recognition of symptoms. Objective To analyze the effectiveness of implementing protocols for acute ischemic stroke in reducing care time. Methods Systematic review, which was performed with primary studies in Portuguese, English, and Spanish published between 2011 and 2020. Inclusion criteria: study population should comprise people with acute ischemic stroke and studies should present results on the effectiveness of using urgent care protocols in reducing care time. The bibliographic search was conducted in June 2020 in the LILACS, MEDLINE, Embase, Scopus, CINAHL, Academic Search Premier, and SocINDEX databases. The articles were selected, and data were extracted by two independent reviewers; the synthesis of the results was performed narratively. The methodological quality of articles was evaluated through specific instruments proposed by the Joanna Briggs Institute. Results A total of 11,226 publications were found, of which 35 were included in the study. Only one study reported improvement in the symptoms-onset-to-door time after protocol implementation. The effectiveness of the therapeutic approach protocols for ischemic stroke was identified in improving door-to-image, image-to-needle, door-to-needle and symptoms-onset-to-needle times. The main limitation found in the articles concerned the lack of clarity in relation to the study population. Conclusions Several advances have been identified in in-hospital care with protocol implementation; however, it is necessary to improve the recognition time of stroke symptoms among those who have the first contact with the person affected by the stroke and among the professionals involved with the prehospital care.

Resumo Antecedentes O tratamento do acidente vascular cerebral (AVC) isquêmico com terapia de reperfusão requer rápido atendimento e reconhecimento dos sintomas. Objetivo Analisar a efetividade da implementação de protocolos para AVC isquêmico agudo na redução do tempo de atendimento. Métodos Revisão sistemática realizada com estudos primários em português, inglês e espanhol publicados entre 2011 e 2020. Critérios de inclusão: a população do estudo foi constituída por pessoas com AVC isquêmico agudo e estudos que apresentassem resultados sobre a efetividade da implantação de protocolos no tempo de atendimento. A pesquisa bibliográfica foi realizada em junho de 2020 nas bases de dados LILACS, MEDLINE, Embase, Scopus, CINAHL, Academic Search Premier e SocINDEX. A seleção dos artigos e a extração dos dados foram feitas por dois revisores independentes; a síntese dos resultados foi feita de forma narrativa. A qualidade metodológica dos artigos foi avaliada por meio de instrumentos do Joanna Briggs Institute. Resultados Foram encontradas 11.226 publicações, das quais 35 foram incluídas no estudo. Apenas um estudo relatou melhora no tempo início dos sintomas-porta após a implementação do protocolo, no entanto, foi efetiva na melhora dos tempos porta-imagem, imagem-agulha, porta-agulha e início dos sintomas-agulha. A principal limitação encontrada nos artigos diz respeito à falta de clareza quanto à população de estudo. Conclusões Vários avanços foram identificados no atendimento intra-hospitalar com implantação de protocolo; porém, é necessário melhorar o tempo de reconhecimento dos sintomas do AVC entre aqueles que têm o primeiro contato com a pessoa acometida e entre os profissionais envolvidos com o atendimento pré-hospitalar.

https://doi.org/10.1055/s-0042-1755194

10.

Doença de Madelung: abordagem cirúrgica combinada de lipectomia e lipoaspiração
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PERSEGUIM, AMANDA BISHOP

; AQUINO, JOSÉ LUIZ BRAGA DE

; PEREIRA, DOUGLAS ALEXANDRE RIZASTE

; RODRIGUES-SILVA, ANA MARIA GODOY MOREIRA

; DE-FARIA, JOSE CARLOS MARQUES

Revista Brasileira de Cirurgia Plástica

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Mar 2022, Volume 37 Nº 1 Páginas 105 - 110

Resumo: Pt En | Texto: Pt En | PDF: Pt | PDF: En

RESUMO A doença de Madelung (DM) ou lipomatose simétrica múltipla é uma patologia caracterizada pelo acúmulo de tecido adiposo não encapsulado e depositado simetricamente ao redor do pescoço e tronco superior (tipo I - forma mais comum). Sua etiologia ainda é pouco esclarecida, porém apresenta evidente associação com o consumo crônico excessivo de bebidas alcoólicas. As deformidades físicas são o que levam o paciente a buscar serviço médico, juntamente com eventuais sintomas de acometimento cervical como redução de mobilidade e afecções respiratórias. O diagnóstico da lipomatose simétrica múltipla é clínico, podendo ser complementado com exame de imagem para afastar demais hipóteses diagnósticas e avaliar a extensão do acometimento. O tratamento pode ser realizado por duas modalidades: clínico ou cirúrgico (lipectomia ou lipoaspiração). Relata-se o caso de paciente com lipomatose simétrica múltipla tipo I abordado cirurgicamente com ambas as técnicas: lipectomia cervical e lipoaspiração abdominal. Paciente evoluiu de maneira satisfatória, com redução de queixas e sem recidivas até o presente momento.

ABSTRACT Madelung’s disease (MD) or Multiple Symmetric Lipomatosis is a condition characterized by the accumulation of unencapsulated adipose tissue deposited symmetrically around the neck and upper trunk (type I - most common form). Its etiology is still unclear, but it is clearly associated with chronic excessive consumption of alcoholic beverages. Physical deformities lead the patient to seek medical care, along with possible symptoms of cervical involvement such as reduced mobility and respiratory disorders. Multiple Symmetric Lipomatosis diagnosis is clinical and can be complemented with imaging to rule out other diagnostic hypotheses and assess the extent of involvement. Treatment can be performed in two ways: clinical or surgical (lipectomy or liposuction). We report the case of a patient with Multiple Symmetric Lipomatosis type I surgically treated with both techniques: cervical lipectomy and abdominal liposuction. The patient evolved satisfactorily, with a reduction in complaints and no recurrences so far.

https://doi.org/10.5935/2177-1235.2022rbcp0018

11.

NATURAL DISTRIBUTION OF Myracrodruon urundeuva FR. ALL. IN BRAZIL AT CURRENT AND FUTURE CLIMATE SCENARIOS DUE TO GLOBAL CLIMATE CHANGE
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Capo, Lorena Frigini Moro

; Moraes, Mario Luiz Teixeira de

; Zulian, Daniele Fernanda

; Wrege, Marcos Silveira

; Portela, Renan Marcelo

; Cambuim, José

; Silva, Alexandre Marques Da

; Soares, Márcia Toffani Simão

; Sousa, Valderês Aparecida de

; Aguiar, Ananda Virginia de

Revista Árvore

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2022, Volume 46 elocation e4609

Resumo: Pt En | Texto: Pt En | PDF: Pt | PDF: En

RESUMO Neste trabalho, foi realizada a previsão da distribuição de M. urundeuva Fr. All., com base na região de ocorrência natural da espécie. Suas coordenadas geográficas foram obtidas nas bases de dados online CRIA e SpecialLinks, a partir de artigos científicos e trabalhos de campo realizados pela Universidade Estadual Paulista (UNESP) em Ilha Solteira, São Paulo, Brasil. M. urundeuva é uma espécie arbórea nativa com grande potencial para uso comercial no Brasil. Para tanto, foi utilizada a modelagem de nicho ecológico, com camadas atuais de variáveis climáticas e camadas preparadas para cenários climáticos futuros, de acordo com o 4º Relatório do Painel Intergovernamental sobre Mudanças Climáticas (AR4/IPCC), utilizando dados do Worldclim no Brasil. Com os programas Open Modeller e ArcGIS, foram gerados mapas para prever sua ocorrência para o período atual e para cenários climáticos futuros, feitos de acordo com as projeções de mudanças climáticas globais. Com a projeção de aumentos de temperatura e precipitação na região onde ocorre a espécie, ela tende a migrar para áreas do Brasil onde o clima é atualmente mais ameno, nas regiões Sul e Sudeste. Devido às mudanças climáticas, a espécie tende a sofrer mudanças na distribuição e tamanho de área até 2080. Foi projetado para a Caatinga e Pantanal, nos dois períodos, um aumento de área, enquanto para o Cerrado, no primeiro período, a área aumentou e para o segundo, diminuiu. Portanto, de acordo com os resultados dos mapas de projeções futuras para as próximas décadas, conclui-se que haverá mudanças na distribuição de M. urundeuva, com redução significativa da área potencial de ocorrência na região.

ABSTRACT In this work, the prediction of the distribution of M. urundeuva Fr. All. was performed based on the region of natural occurrence of the species. Its geographic coordinates were obtained from online databases CRIA and SpecialLinks, from scientific articles and fieldwork carried out by Universidade Estadual Paulista (UNESP) in Ilha Solteira, São Paulo, Brazil. M. urundeuva is a native tree species with great potential for commercial use in Brazil. For this purpose, ecological niche modeling was used, with current layers of climate variables and layers prepared for future climate scenarios, according to the 4th Report of the Intergovernmental Panel on Climate Change (AR4/IPCC), using Worldclim data on Brazil. With the Open Modeller and ArcGIS programs, maps were generated to predict its occurrence for the current period and future climate scenarios, made according to the projections of global climate changes. With the projection of increases in temperature and precipitation in the area where the species occurs, it tends to migrate to areas of Brazil where the climate is currently milder, in the south and southeast regions. Due to climatic changes, the species tends to undergo changes in distribution and area size until 2080. It was projected for Caatinga and Pantanal, in both periods, an increase in area, while for the Cerrado, in the first period, the area increased, and, for the second, it decreased. Therefore, according to the results of the maps of future projections for the next decades, it is concluded that there will be changes in the distribution of M. urundeuva, with a significant reduction of the potential area of occurrence in the region.

https://doi.org/10.1590/1806-908820220000009

12.

Bixinoids Derived from Bixa orellana as a Potential Zika Virus Inhibitor Using Molecular Simulations. Antiviral Effect on the Zika Virus of Bixinoids
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Nogueira Sobrinho, Antonio Carlos

; Roberto, Caio Henrique Alexandre

; Lima, Danielle Malta

; Fonseca, Aluisio Marques da

; Marinho, Emmanuel Silva

Brazilian Archives of Biology and Technology

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2022, Volume 65 elocation e22210032

Resumo: En | Texto: En | PDF: En

Abstract Zika fever is a viral infection of great relevance in public health, especially in tropic regions, in which there is a predominance of mosquitoes of the genus Aedes, vectors of the disease. Microcephaly in neonatal children and Guillain-Barré syndrome in adults can be caused by the action of the Zika virus (ZIKV). Non-structural proteins, such as NS2B, NS3 and NS5, are important pharmacological targets, due to their action in the life cycle. The absence of anti-Zika drugs raises new research, including prospecting for natural products. This work investigated the in silico antiviral activity of bixin and six other derived molecules against the Zika viral proteins NS2B-NS3 and NS5. The optimized structure was subjected to molecular docking to characterize the interaction between bixinoids and ZIKV non-structural proteins, where significant interactions were observed with amino acid residues in the catalytic site in each enzyme. These results suggest that bixin and ethyl bixin has the potential to interfere with the enzymatic activity of NS2B, NS3 and NS5, thus being an indication of being a promising anti-Zika agent.

https://doi.org/10.1590/1678-4324-2022210032

13.

Cured dry smoked shoulder meat quality from culled adult goats fed a high lipid diet
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OLIVEIRA, Felipe Brener Bezerra de

; FERNANDES, César Carneiro Linhares

; MONTENEGRO, Assis Rubens

; OLIVEIRA, Iolly Tabata Marques

; SILVA, Caroline Pessoa

; LIMA, Francisco Wellington Rodrigues

; CARNEIRO, Hilton Alexandre Vidal

; BESERRA, Frederico José

; RÊGO, Aníbal Coutinho do

; RONDINA, Davide

Food Science and Technology

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2022, Volume 42 elocation e19521

Resumo: En | Texto: En | PDF: En

Abstract The effect of high dietary lipid on the meat quality parameters of shoulder meat adult goats in raw meat and during curing and smoking was evaluated by classical and multivariate approaches. The animals were divided into two groups of different finishing strategies: without whole full-fat linseed (WFFLG, n = 9) and whole full-fat linseed (FFLG, n = 9), with diets containing an ether extract content of 2.7% and 6.9%, respectively. The physicochemical attributes did not vary according to the experimental diets in raw meat. The colorimetric parameters and pH varied during curing and smoking. Through multivariate analysis the first two principal components (PC), it was possible to identified variables were highly importance the total variation (L*, a*, b*, C*, h*, and fat content) in raw meat and smoking. The fat content and color b* presented the highest scores for importance of the variable in the projection. Lipid supplementation of adult goats did not influence the quality parameters physicochemical of the raw shoulder meat. However, after curing and smoking there was a significant effect of diet on Hue angle (h*).

https://doi.org/10.1590/fst.19521

14.

Psychometric properties of the Brief Symptom Inventory support the hypothesis of a general psychopathological factor
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Serpa, Alexandre Luiz de Oliveira

; Costa, Danielle Souza

; Ferreira, Clarice de Medeiros Chaves

; Pinheiro, Mayra Isabel C.

; Diaz, Alexandre Paim

; de Paula, Jonas Jardim

; Miranda, Debora Marques

; da Silva, Antônio Geraldo

; Malloy-Diniz, Leandro Fernandes

Trends in Psychiatry and Psychotherapy

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2022, Volume 44 elocation e20210207

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Abstract Introduction The existence of a general factor related to psychiatric symptoms is supported by studies using a variety of methods in both clinical and non-clinical samples. Objectives This study aims to evaluate the replicability of the internal structure of the Brief Symptom Inventory in a large Brazilian sample. Methods Participants were 6,427 Brazilian subjects (81% female). Mean age was 42.1 years (standard deviation [SD] = 13.6, Min = 13, Max = 80). All participants completed the online version of the Brief Symptom Inventory. This scale presents a general score (GSI) and nine specific clusters of symptoms (depression, anxiety, phobic anxiety, interpersonal sensibility, psychoticism, paranoid ideation, obsessive-compulsive behavior, hostility, and somatization symptoms). Results Confirmatory factor analysis was performed to assess the factor structure of the BSI. The results showed that the best-fitting model was a bifactor solution and the general factor was the main dimension explaining most of the reliable variability in the data. Conclusion The findings suggest that the BSI’s internal structure was replicated in a non-clinical sample and that the general factor is the most reliable score. However, it is necessary to better understand the meaning of the general factor scores in a non-clinical sample to increase interpretability of scores.

https://doi.org/10.47626/2237-6089-2021-0207

15.

Variability and genetic associations of pigeon pea yield traits in Mozambique
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Pedro, César

; Cruz, Cosme Damião

; Donça, Marques Cachisso Bambo

; Somueque, Salva Inácio

; Gimo, Sabir Tualibo

; Silva, Michele Jorge da

; Ferraz, Alexandre Gomes

; Rosado, Renato Domiciano Silva

; Bhering, Leonardo Lopes

Pesquisa Agropecuária Brasileira

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2022, Volume 57 elocation e02703

Resumo: Pt En | Texto: Pt En | PDF: Pt | PDF: En

Resumo O objetivo deste trabalho foi avaliar a variabilidade genética e as associações de características produtivas do feijão-bóer, para indicação dessa cultura ao programa de melhoramento em Moçambique. Foram avaliadas 11 características do feijão-bóer, em delineamento de três blocos ao acaso, nos ambientes de Namapa (I) e Montepuez (II), em 2017/2018. Para avaliação das características, utilizaram-se análises de variância, parâmetros genéticos, correlações, rede de correlação e análise de trilha. Em ambos os ambientes, há alta variabilidade genética e fenotípica para ramos primários, ramos secundários, vagens por planta, número de sementes por vagem, largura e comprimento da vagem e produtividade, bem como alta herdabilidade para todas as características, exceto para altura da planta. Os ramos primários e secundários apresentam alta correlação com a produtividade e efeito direto positivo sobre ela. No entanto, altura de planta e vagens por planta apresentam alta variabilidade fenotípica e correlação positiva com a produtividade no ambiente I. Vagens por planta, peso de 100 sementes e ramos primários apresentam altos efeitos positivos diretos no ambiente I, e ramos secundários e número de sementes por vagem, no ambiente II. Os ramos primários e secundários apresentam alta variabilidade e associações com a produtividade em ambos os ambientes e são indicados para o programa de melhoramento do feijão-bóer em Moçambique.

Abstract The objective of this work was to evaluate the genetic variability and associations of yield traits of pigeon pea, for indication of this crop for the breeding program in Mozambique. Eleven pigeon pea traits were evaluated in a experimental design with three randomized complete blocks, in the environments of Namapa (I) and Montepuez (II), in 2017/2018. To evaluate the traits, analyses of variance, genetic parameters, correlations, correlation network, and path analysis were used. In both environments, there is a high genetic and phenotypic variability for primary branches, secondary branches, pods per plant, number of seed per pod, pod width, pod length, and yield, as well as a high heritability for all traits except for plant height. The primary and secondary branches have a high correlation with yield and a positive direct effect on it. However, plant height and pods per plant show a high phenotypic variability and a positive correlation with yield in environment I. Pods per plant, weight of 100 seed, and primary branches show high direct positive effects in environment I, and secondary branches and number of seed per pod, in environment II. The primary and secondary branches show high variability and associations with yield in both environments and are indicated for the pigeon pea breeding program in Mozambique.

https://doi.org/10.1590/s1678-3921.pab2022.v57.02703

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