Pesquisa | SciELO

ABSTRACT Sweet potato is among the most important food crops in the world. Due to its high genetic diversity, this species has cultivars that can respond in different ways depending on mineral fertilization. Among the nutrients, phosphorus is related to physiological and biochemical processes that can influence the final quality of the product. This study aimed to assess the influence of P doses on the quality and bioactive compounds of sweet potato cultivars - Paraná, BRS Amélia, and BRS Cuia. The pH, soluble solids (SS), titratable acidity (TA), SS/TA ratio, soluble sugars, and the bioactive compounds - flavonoids, anthocyanins, and carotenoids - were evaluated. The P doses influenced sweet potato cultivars. The dose of 120 kg ha-1 promoted increments in the parameters pH, SS, TA, and SS/TA ratio for the cultivar BRS Cuia. The same dose promoted an increase in total soluble sugars for the cultivar BRS Amélia. P dose of 240 kg ha-1 promoted higher levels of flavonoids and anthocyanins in the cultivar Paraná, and there was an increase in carotenoid content at the dose of 60 kg ha-1.

RESUMO A batata-doce está entre as culturas alimentícias mais importantes do mundo. Por apresentar alta diversidade genética, essa espécie possui cultivares que podem responder de maneiras diferentes em função da adubação mineral. Dentre os nutrientes, o fósforo está relacionado com processos fisiológicos e bioquímicos que podem influenciar na qualidade final do produto. Este estudo teve como objetivo avaliar a influência de doses de P na qualidade e compostos bioativos de cultivares de batata-doce - Paraná, BRS Amélia e BRS Cuia. Foram avaliados o pH, sólidos solúveis (SS), acidez titulável (AT), relação SS/AT, açúcares solúveis e os compostos bioativos - flavonoides, antocianinas e carotenoides. As doses de P influenciaram as cultivares de batata-doce. A dose de 120 kg ha-1 promoveu incrementos nos parâmetros pH, SS, AT e relação SS/AT para a cultivar BRS Cuia. A mesma dose promoveu incrementos nos açúcares solúveis totais para a cultivar BRS Amélia. A dose de 240 kg ha-1 promoveu maiores teores de flavonoides e antocianinas na cultivar Paraná, e houve aumento no teor de carotenoides na dose de 60 kg ha-1.

https://doi.org/10.1590/1807-1929/agriambi.v28n1e274451

Mucuna cinerea Seeds: Levodopa Extraction Using Deep Eutectic Solvent and Its Mammalian Cell Activity
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Silva, Bruna T.

; Demuner, Antonio J.

; Blank, Daiane E.

; Campos, Mateus G.

; Mendes, Tiago A. O.

Journal of the Brazilian Chemical Society

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2024, Volume 35 Nº 1 elocation e-20230101

Resumo: En | Texto: En | PDF: En

A new class of deep eutectic solvents (DES) was used in the extraction of levodopa (L-dopa) present in Mucuna cinerea, which has been termed “green” or “designer” solvents, with notable productive and economic/environmental benefits. The seeds of Mucuna cinerea were prepared and submitted to extraction with heating and agitation in a solvent mixture of DES with citric acid, urea, or glycerol. The extracts were analyzed by high performance liquid chromatography (HPLC) which confirmed the efficiency of DES in extracting L-dopa. These extractions were carried out to determine the L-dopa extracts in DES with regard to the induction of cellular response activity, demonstrating the synergy between L-dopa and DES. The DES-glycerol extract exhibited a higher proliferative activity than commercial L-dopa after 24 h of treatment. The human glandular kallikrein-1 gene (hGK3) demonstrated higher expression in the treatment with the DES-urea, while the G protein-coupled receptor kinase-6 gene (GRK6) showed higher expression for all extracts compared to commercial L-dopa, with a higher value obtained for DES glycerol, followed by DES urea extract. The DES extraction method is therefore promising and unprecedented, confirming its possible use in the replacement of expensive solvents, supporting the use of ecologically viable DES in the extractions of other plant species.

https://doi.org/10.21577/0103-5053.20230101

[SciELO Preprints] - Cardiovascular Statistics – Brazil 2023
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Oliveira, Gláucia Maria Moraes de Brant, Luisa Campos Caldeira Polanczyk, Carisi Anne Malta, Deborah Carvalho Biolo, Andreia Nascimento, Bruno Ramos Souza, Maria de Fatima Marinho de Lorenzo, Andrea Rocha De Fagundes Júnior, Antonio Aurélio de Paiva Schaan, Beatriz D. Silva, Christina Grüne de Souza e Castilho, Fábio Morato de Cesena, Fernando Henpin Yue Soares, Gabriel Porto Xavier Junior, Gesner Francisco Barreto-Filho, Jose Augusto Soares Passaglia, Luiz Guilherme Pinto-Filho, Marcelo Martins Machline-Carrion, M. Julia Bittencourt, Marcio Sommer Pontes Neto, Octavio M. Villela, Paolo Blanco Teixeira, Renato Azeredo Stein, Ricardo Sampaio, Roney Orismar Gaziano, Thomaz A. Perel, Pablo Roth, Gregory A. Ribeiro, Antonio Luiz Pinho

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Data de publicação: 2023-12-14

Resumo: En Pt

The publication Cardiovascular Statistics – Brazil aims to provide an annual compilation of data and research on the epidemiology of CVDs in Brazil.  The report integrates official statistics from the Brazilian Ministry of Health and other governmental entities alongside data from the GBD project, coordinated by the IHME at the University of Washington. Additionally, it incorporates data derived from various sources and scientific studies, including cohorts and registries, that relate to CVDs and their associated risk factors. This publication is intended for a wide range of individuals, including researchers, clinicians, patients, healthcare policymakers, media professionals, the general public, and other interested parties seeking extensive national data about heart disease and stroke.  Volunteer researchers from various Brazilian universities and research institutions carry out the project. The group is led by a five-member steering committee (ALPR, CAP, DCM, GMMO, and LCCB). The Brazilian Society of Cardiology fully supports this initiative, and the project receives collaborative support from the GBD Brazil Network and an International Committee (GAR, PP, and TAG) from both the IHME/University of Washington (GAR) and the World Heart Federation (PP and TAG). 

A publicação Estatística Cardiovascular – Brasil tem por objetivo fornecer uma compilação anual dos dados e das pesquisas sobre a epidemiologia das DCV no Brasil.  Este documento integra as estatísticas oficiais do Ministério da Saúde do Brasil e outras entidades governamentais ao lado de dados do projeto GBD, coordenado pelo IHME da Universidade de Washington. Além disso, incorpora dados derivados de várias fontes e estudos científicos, inclusive coortes e registros, relacionados às DCV e fatores de risco associados. Esta publicação destina-se a um público variado, incluindo pesquisadores, clínicos, pacientes, formuladores de políticas de saúde, profissionais da mídia, o público em geral e todos aqueles que buscam dados nacionais abrangentes sobre DCV e acidente vascular cerebral. Pesquisadores voluntários de várias universidades e instituições de pesquisa brasileiros realizaram este projeto. O grupo é liderado por um comitê diretivo com cinco membros (ALPR, CAP, DCM, GMMO e LCCB). A Sociedade Brasileira de Cardiologia apoia integralmente esta iniciativa e o projeto recebe colaboração da Rede GBD Brasil1 e do GBD International Committee (GAR, PP e TAG) do IHME/Universidade de Washington (GAR) e da World Heart Federation (PP e TAG). 

https://doi.org/10.1590/SciELOPreprints.7707

Long-term oncological and surgical outcomes after Video Endoscopic Inguinal Lymphadenectomy (VEIL) in patients with penile cancer
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Tobias-Machado, Marcos

; Ornellas, Antonio A.

; Hidaka, Alexandre K.

; Medina, Luis G.

; Mattos, Pablo A. L.

; Besio, Ruben S.

; Abreu, Diego

; Castro, Pedro R.

; Nishimoto, Ricardo H.

; Astigueta, Juan

; Dourado, Aurus

; Machado, Roberto D.

; Magnabosco, Wesley J.

; Corona-Montes, Victor

; Villoldo, Gustavo M.

; Zampolli, Hamilton C.

; Taha, Anis

; Auad, Pericles R.

; Faria, Eliney F.

; Arantes, Paulo B. O.

; Tavares, Alessandro

; Nascimento, Francisco S. M. S.

; Brazão Jr., Eder S.

; Rocha, Maurício M.

; Costa, Walter H.

; Panico, Vinicius

; Reis, Leonardo O.

; Almeida-Carrera, Roberto J.

; Silva, Rafael C.

; Zequi, Stênio C.

; Calixto, José R. R.

; Sotelo, Rene

International braz j urol

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Out 2023, Volume 49 Nº 5 Páginas 580 - 589

Resumo: En | Texto: En | PDF: En

ABSTRACT Objective: To report outcomes from the largest multicenter series of penile cancer patients undergoing video endoscopic inguinal lymphadenectomy (VEIL). Materials and Methods: Retrospective multicenter analysis. Authors of 21 centers from the Penile Cancer Collaborative Coalition-Latin America (PeC-LA) were included. All centers performed the procedure following the same previously described standardized technique. Inclusion criteria included penile cancer patients with no palpable lymph nodes and intermediate/high-risk disease and those with non-fixed palpable lymph nodes less than 4 cm in diameter. Categorical variables are shown as percentages and frequencies whereas continuous variables as mean and range. Results: From 2006 to 2020, 210 VEIL procedures were performed in 105 patients. Mean age was 58 (45-68) years old. Mean operative time was 90 minutes (60-120). Mean lymph node yield was 10 nodes (6-16). Complication rate was 15.7%, including severe complications in 1.9% of procedures. Lymphatic and skin complications were noted in 8.6 and 4.8% of patients, respectively. Histopathological analysis revealed lymph node involvement in 26.7% of patients with non-palpable nodes. Inguinal recurrence was observed in 2.8% of patients. 10y- overall survival was 74.2% and 10-y cancer specific survival was 84.8%. CSS for pN0, pN1, pN2 and pN3 were 100%, 82.4%, 72.7% and 9.1%, respectively. Conclusion: VEIL seems to offer appropriate long term oncological control with minimal morbidity. In the absence of non-invasive stratification measures such as dynamic sentinel node biopsy, VEIL emerged as the alternative for the management of non-bulky lymph nodes in penile cancer.

https://doi.org/10.1590/s1677-5538.ibju.2023.0065

Foliar nitrogen fertilization attenuating harmful effects of salt stress on purple basil
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Nóbrega, Jackson S.

; Silva, Toshik I. da

; Lopes, Adriano S.

; Costa, Raimundo N. M.

; Ribeiro, João E. da S.

; Silva, Edcarlos C. da

; Bezerra, Ana C.

; Silva, Antônio V. da

; Dias, Thiago J.

Revista Brasileira de Engenharia Agrícola e Ambiental

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Jun 2023, Volume 27 Nº 6 Páginas 472 - 479

Resumo: En Pt | Texto: En Pt | PDF: En | PDF: Pt

ABSTRACT Salinity can have detrimental effects on plant development. To minimize this damage, strategies such as balanced maintenance of plants’ nutritional status have been proposed previously. The objective of this study is to investigate whether the optimization of foliar nitrogen fertilization can promote the growth and photochemical efficiency of purple basil subjected to salt stress. The experiment was performed using a randomized block design with an incomplete 5 × 5 factorial arrangement generated through experimental matrix Central Composite Design with two parameters: salinity of irrigation water at 0.5, 0.81, 2.75, 4.69, and 5.50 dS m-1; and nitrogen doses at 0, 58.58, 200, 341.42, and 400 mg L-1. It was found that an increase in the salinity of irrigation water reduced the growth and photochemical efficiency of purple basil. However, the foliar application of nitrogen at the concentration of 400 mg L-1 attenuated the harmful effects of salinity on both the absolute and relative growth rates of stem diameter, the relative growth of plant height, and chlorophyll A fluorescence. These results showed that foliar nitrogen fertilization is a suitable strategy to help mitigate salt stress in basil plants.

RESUMO A salinidade pode promover efeitos danosos ao desenvolvimento vegetal, sendo o necessário o uso de estratégias para minimizar os danos promovidos, como a manutenção equilibrada do estado nutricional da planta. Assim, o objetivo deste estudo foi avaliar o efeito da adubação nitrogenada foliar e da salinidade no crescimento e eficiência fotoquímica de manjericão roxo. O experimento foi conduzido com o delineamento de blocos casualizados, em arranjo fatorial incompleto 5 × 5 (salinidades da água de irrigação: 0,5; 0,81; 2,75; 4,69 e 5,50 dS m-1 × doses de nitrogênio: 0; 58,58; 200; 341,42 e 400 mg L-1), gerados através da matriz experimental Composto Central de Box. O aumento da salinidade da água de irrigação reduz o crescimento e a eficiência fotoquímica das plantas de manjericão roxo. Todavia, a aplicação foliar de 400 mg L-1 de N atenuou os efeitos deletérios da salinidade sobre as taxas de crescimento absoluto e relativo para o diâmetro do caule e relativo para a altura de plantas, assim como na fluorescência da clorofila a. Esses resultados mostram que a adubação foliar nitrogenada é uma estratégia para mitigar o estresse salino em plantas de manjericão.

https://doi.org/10.1590/1807-1929/agriambi.v27n6p472-479

Gas exchange and photochemical efficiency of guava under saline water irrigation and nitrogen-potassium fertilization
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Nobre, Reginaldo G.

; Rodrigues Filho, Ricardo A.

; Lima, Geovani S. de

; Linhares, Edna L. da R.

; Soares, Lauriane A. dos A.

; Silva, Luderlândio de A.

; Teixeira, Antônio D. da S.

; Macumbi, Nelson J. V.

Revista Brasileira de Engenharia Agrícola e Ambiental

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Mai 2023, Volume 27 Nº 5 Páginas 429 - 437

Resumo: En Pt | Texto: En Pt | PDF: En | PDF: Pt

ABSTRACT The objective of this study was to evaluate the effects of different combinations of nitrogen and potassium fertilization on gas exchange and chlorophyll a fluorescence in seedlings of guava cv. Paluma irrigated with water of different salinity levels. The experiment was set up in a randomized block design and analyzed in 5 × 4 factorial scheme, with four replicates. The treatments were composed of the combination of the factor electrical conductivity of irrigation water - ECw (0.3, 1.1, 1.9, 2.7, and 3.5 dS m-1), with the factor combinations (C) formed from recommended doses of nitrogen (N) and potassium (K2O), 70% N + 50% K2O, 100% N + 75% K2O, 130% N + 100% K2O, and 160% N + 125% K2O. The fertilization combination 130% N + 100% K2O mitigated the effects of salt stress up to mean ECw of 1.3 dS m-1, resulting in increments in CO2 assimilation rate, transpiration, instantaneous carboxylation efficiency, and electron transport rate. For maximum quantum efficiency of photosystem II, only treatment irrigated with ECw 3.5 dS m-1 under the combination 160% N + 125% K2O showed damage to the photosynthetic apparatus.

RESUMO Objetivou-se com o presente estudo avaliar os efeitos de diferentes combinações de adubação nitrogenada e potássica sobre as trocas gasosas e fluorescência da clorofila a em mudas de goiabeira cv. Paluma irrigadas com águas de distintas salinidades. O experimento foi instalado em delineamento em blocos casualizados e analisados no esquema fatorial 5 × 4, com quatro repetições. Os tratamentos foram compostos a partir da combinação do fator condutividade elétrica da água de irrigação - CEa (0,3; 1,1; 1,9; 2,7 e 3,5 dS m-1) com o fator combinações (C) formada a partir de doses recomendadas de nitrogênio (N) e potássio (K2O): 70% N + 50% K2O; 100% N + 75% K2O; 130% N + 100% K2O e 160% N + 125% K2O. A combinação de adubação 130% N + 100% K2O mitigou o estresse salino até a CEa média de 1,3 dS m-1, resultando em aumento na taxa de assimilação de CO2, transpiração, eficiência instantânea de carboxilação e taxa de transporte de elétrons. Para a máxima eficiência quântica do fotossistema II, apenas os tratamentos irrigados com CEa 3,5 dS m-1 e combinação 160% N + 125% K2O apresentaram danos no aparelho fotossintético.

https://doi.org/10.1590/1807-1929/agriambi.v27n5p429-437

Absorb/Transmit Broadband Type Frequency Selective Surface
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G. P. Neto, José Jaime

; Campos, Antonio Luiz P. S.

; Lira, Ruann Victor de A.

; Gomes Neto, Alfredo

; Silva, Maurício W. B.

Journal of Microwaves, Optoelectronics and Electromagnetic Applications

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Mar 2023, Volume 22 Nº 1 Páginas 1 - 12

Resumo: En | Texto: En | PDF: En

Abstract Frequency Selective Surfaces (FSS) are increasingly being used in telecommunications systems due to the numerous advantages presented by this sort of structure, among them low cost, ease of fabrication, and low profile stand out. This work reports the design, fabrication, and characterization of a multilayer frequency-selective absorber (FSA) for broadband operation. The proposed structure shows an absorption performance (operating in the frequency range between 2 GHz and 6 GHz) within the transmission band. The absorber consists of cascaded frequency selective surfaces, which are composed of both conductive square loops, which reflect incident signals, and resistive ones, which act as an absorbing layer. To verify the absorbing structure performance, full-wave numerical simulations and measurements are presented. The measured results are in good agreement with the numerical ones and show that the design performs absorption above 80% within the range of 2.48 GHz to 6.13 GHz, which verifies the project properties. Besides that, numerical results show that the proposed absorber has a proper response under oblique incidence up to 30°.

https://doi.org/10.1590/2179-10742023v22i1268430

Enhanced Larvicidal Activity of New 1,2,4-Oxadiazoles against Aedes aegypti Mosquitos: QSAR and Docking Studies
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Silva, Aluízio G. da

; Navarro, Daniela Maria A. F.

; Santos, Geanne K. N.

; Aguiar, Júlio César R. O. F. de

; França, Karla A. de

; Tébéka, Iris Raquel M.

; Anjos, Janaína V. dos

; Silva, João Bosco P. da

; Kanis, Luiz A.

; Srivastava, Rajendra M.

; Neves Filho, Ricardo Antônio W.

; Ramos, Mozart N.

Journal of the Brazilian Chemical Society

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Mar 2023, Volume 34 Nº 3 Páginas 333 - 345

Resumo: En | Texto: En | PDF: En

The worldwide emergence of viral diseases such as Zika, Dengue, Chikungunya, West Nile and Yellow Fever urge the search for solutions to eliminate their common vector, the Aedes aegypti mosquito. This paper describes the quantitative structure-activity relationship (QSAR) and docking studies of a series of nine 3-(3-aryl-1,2,4-oxadiazol-5-yl)propionic acids (AOPA), 1-9, previously published by our group. Additionally, three new 1,2,4-oxadiazoles, 10-12, have also been synthesized, characterized and studied. The QSAR and docking studies of all compounds, 1-12, clearly indicate that larger hydrophobic substituents such as biphenyl groups attached on position 3 in 1,2,4-oxadiazoles improve the larvicidal activity. It is worthwhile to mention that nanocapsulation of compounds 10-12 were necessary to help their dissolution in water and these three new 1,2,4-oxadiazoles also exhibited approximately equal or higher larvicidal activities compared to the former prototypes at stage L4.

https://doi.org/10.21577/0103-5053.20220112

Low-Temperature Partitioning: A Simple Screening Method for Determining Diethylene Glycol in Beer by Gas Chromatography
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Azevedo, Mariane M.

; Miranda, Liany D. L.

; Queiroz, Maria Eliana L. R. de

; Oliveira, André F. de

; Pereira, Alexandre F.

; Neves, Antônio A.

; Silva, Thaís L. R.

Journal of the Brazilian Chemical Society

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Mar 2023, Volume 34 Nº 3 Páginas 452 - 460

Resumo: En | Texto: En | PDF: En

Diethylene glycol is an extremely toxic substance to humans. Recently, cases of beer contamination in Brazil have raised awareness of the need for developing simple screening methods to evaluate this type of compound. This research developed a liquid-liquid extraction with low-temperature partitioning technique to determine diethylene glycol in beer via gas chromatography. Employing a flame-ionization detector simplifies the method, lowers its cost and therefore, it can be used as screening step to assess the possibility of contamination. A gas chromatograph coupled to a mass spectrometer would be used only for a confirmatory analysis. The optimized method was validated for the main figures of merit, and it proved to be adequate, with good values of recovery rate (94-106%), limit of detection (3.0 mg L-1), and quantification (10.0 mg L-1). Accuracy, in terms of repeatability and intermediate accuracy, showed variation coefficients lower than or equal to 20%. This method was applied to 28 samples of beers marketed in Brazil, and diethylene glycol was found above the limit of detection in three of them (10.7%). These results were confirmed by a gas chromatograph coupled to a mass spectrometer, which showed the reliability of the screening method for determining diethylene glycol in beer samples.

https://doi.org/10.21577/0103-5053.20220123

10.

Mechanized harvesting of conilon coffee plants using a self-propelled machine
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Souza, Gustavo S. de

; Bouzan, Antônio M. B.

; Infantini, Maurício B.

; Silva, Samuel de A.

; Almeida, Robson F. de

Revista Brasileira de Engenharia Agrícola e Ambiental

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Fev 2023, Volume 27 Nº 2 Páginas 140 - 148

Resumo: Pt En | Texto: Pt En | PDF: Pt | PDF: En

RESUMO O café é uma das principais commodities do agronegócio mundial e de grande relevância econômica e social para o Brasil. A falta de mão de obra e seu alto custo são fatores que preocupam os cafeicultores, principalmente na colheita do café conilon, feita manualmente. O objetivo deste trabalho foi avaliar a eficiência de uma colhedora automotriz em diferentes condições de ajuste da máquina e condução da lavoura de café conilon e medir sua influência no custo de colheita comparada a colheita manual. Foram avaliados os fatores velocidade de colheita (800 a 1600 m h-1), rotação do cilindro vibrador de varetas (1,0 e 1,5 RPM), número de ramos ortotrópicos (um, dois e três) e plantas com e sem os ramos plagiotrópicos no terço inferior. O aumento da velocidade de colheita reduziu as eficiências de derriça e de colheita e a desfolha. O aumento de um para três ramos ortotrópicos por planta aumentou as eficiências de colheita e de derriça, a perda de chão e a desfolha e reduziu a carga pendente. O manejo sem os ramos plagiotrópicos apresentou maior eficiência de colheita, menor perda de chão e menor desfolha. As velocidades de colheita de 800 a 1600 m h-1 reduziram os custos totais e unitários em até 62% em relação à colheita manual. O aumento da eficiência de colheita acima de 70% reduziu os custos de colheita em até 79% em relação à colheita manual.

ABSTRACT Coffee is one of the main commodities of global agribusiness and of outstanding economic and social relevance for Brazil. The lack of labor and its high cost are factors that worry coffee producers, mainly during the conilon coffee harvesting, which is performed manually. This study aimed to evaluate the efficiency of a self-propelled harvester under different conditions of machine adjustment and conduction of the Coffea canephora crop and measure its influence on the cost of harvesting compared to manual harvesting. Harvesting speed (800 to 1600 m h-1), rotation of the vibrating rod cylinder (1.0 and 1.5 RPM), number of orthotropic branches (one, two, and three), and plants with and without plagiotropic branches in the lower third were assessed. The increase in harvesting speed reduced the efficiencies of stripping and harvesting and defoliation. Increasing from one to three orthotropic branches per plant increased harvesting and stripping efficiencies, fruit loss on the ground, defoliation, and reduced pending load. The management without plagiotropic branches showed higher harvesting efficiency, lower loss on the ground, and lower defoliation. Harvesting speeds from 800 to 1600 m h-1 reduced the total and unit costs up to 62% compared to manual harvesting. Increasing harvesting efficiency above 70% has reduced harvesting costs by up to 79% compared to manual harvesting.

https://doi.org/10.1590/1807-1929/agriambi.v27n2p140-148

11.

The amygdala lesioning due to status epilepticus – Changes in mechanisms controlling chloride homeostasis
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Santos, Luiz E.C.

; Almeida, Antônio-Carlos G.

; Silva, Sílvia C.B.

; Rodrigues, Antônio M.

; Cecílio, Samyra G.

; Scorza, Carla A.

; Finsterer, Josef

; Moret, Marcelo

; Scorza, Fulvio A.

Clinics

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2023, Volume 78 elocation 100159

Resumo: En | Texto: En | PDF: En

Objective: Amygdala has been demonstrated as one of the brain sites involved in the control of cardiorespiratory functioning. The structural and physiological alterations induced by epileptic activity are also present in the amygdala and reflect functional changes that may be directly associated with a sudden unexpected death. Seizures are always associated with neuronal damage and changes in the expression of cation-chloride cotransporters and Na/K pumps. In this study, the authors aimed to investigate if these changes are present in the amygdala after induction of status epilepticus with pilocarpine, which may be directly correlated with Sudden Unexpected Death in Epilepsy (SUDEP). Methods: Pilocarpine-treated wistar rats 60 days after Status Epilepticus (SE) were compared with control rats. Amygdala nuclei of brain slices immunostained for NKCC1, KCC2 and α1-Na+/K+-ATPase, were quantified by optical densitometry. Results: The amygdaloid complex of the animals submitted to SE had no significant difference in the NKCC1 immunoreactivity, but KCC2 immunoreactivity reduced drastically in the peri-somatic sites and in the dendritic-like processes. The α1-Na+/K+-ATPase peri-somatic immunoreactivity was intense in the rats submitted to pilocarpine SE when compared with control rats. The pilocarpine SE also promoted intense GFAP staining, specifically in the basolateral and baso-medial nuclei with astrogliosis and cellular debris deposition. Interpretation: The findings revealed that SE induces lesion changes in the expression of KCC2 and α1-Na + /K + -ATPase meaning intense change in the chloride regulation in the amygdaloid complex. These changes may contribute to cardiorespiratory dysfunction leading to SUDEP.

https://doi.org/10.1016/j.clinsp.2022.100159

12.

Selectivity and efficacy of herbicides applied on barley for weed control
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Galon, Leandro

; Silva, Antonio Marcos Loureiro da

; Franceschetti, Milena Barretta

; Müller, Caroline

; Weirich, Sabrina Natalia

; Toso, Janaíne Oliveira

; Tonin, Rodrigo José

; Perin, Gismael Francisco

Bragantia

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2023, Volume 82 elocation e20220111

Resumo: En | Texto: En | PDF: En

ABSTRACT Ryegrass and turnip are weeds that cause high yield losses when infesting barley, thus requiring adequate management. In this context, the aim of this study was to evaluate the selectivity of different herbicide treatments and weed control in the barley crop, cultivar BRS Cauê. Two field experiments were conducted in randomized blocks, with four replications. The treatments used were: pendimethalin (800 g·ha-1), sulfentrazone + diuron (175 + 350 g·ha-1), and imazaquim (150 g·ha-1 of a. e.) applied pre-emergence; and iodosulfuron (3.5 g·ha-1), pyroxsulam (18 g·ha-1), metsulfuron-methyl (3.96 g·ha-1), 2,4-D (670 g·ha-1 of a. e.), clodinafop-propargyl (48 g·ha-1), bentazon + imazamox (600 + 28 g·ha-1), saflufenacil (49 g·ha-1), bentazon (720 g·ha-1), carfentrazone-ethyl (120 g·ha-1), and imazamox (42 g·ha-1) applied post-emergence, with two controls (one weeded and the other infested). The use of the herbicide imazaquim caused high levels of phytotoxicity in barley. Gas exchange was less responsive to herbicide applications in relation to barley phytotoxicity and productivity. Clodinafop-propargil showed the best control of ryegrass, while the herbicides iodosulfuron, pyroxsulam, metsulfurom-methyl, 2,4-D, bentazon + imazamox, saflufenacil, bentazon, carfentrazone-ethyl, and imazaquim showed high efficiency in the control of turnip species. Imazaquim caused reduction of up to 74.7% in barley grain yield. On the other hand, iodosulufuron and piroxsulam allowed the highest grain yields of the barley cultivar, BRS Cauê, by promoting partial control of ryegrass and total control of turnip species, followed by clodinafop-propargyl and metsulfuron-methyl, which controlled ryegrass and turnip, respectively, allowing an increase in yield grain in relation to the infested control.

https://doi.org/10.1590/1678-4499.20220111

13.

A new synonymy in Anisopodus White (Coleoptera, Cerambycidae, Lamiinae, Acanthocinini)
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Santos-Silva, Antonio

; Nascimento, Francisco Eriberto de Lima

; Mejlon, Hans

Papéis Avulsos de Zoologia

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2023, Volume 63 elocation e202363008

Resumo: En | Texto: En | PDF: En

Abstract Anisopodus subarmatusMelzer, 1931 is synonymized with A. jaculus (Gyllenhal, 1817) and a discussion about the type-locality of the latter is provided. Photographs of the lectotype of the former and of the holotype of the latter are provided.

https://doi.org/10.11606/1807-0205/2023.63.008

14.

Aging-related predictive factors for oxygenation improvement and mortality in COVID-19 and acute respiratory distress syndrome (ARDS) patients exposed to prone position: A multicenter cohort study
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Cunha, Marieta C.A.

; Schardong, Jociane

; Righi, Natiele C.

; Lunardi, Adriana C.

; Sant’Anna, Guadalupe N.

; Isensee, Larissa P.

; Xavier, Rafaela F.

; Pompeu, Jose E.

; Weigert, Renata M.

; Matte, Darlan L.

; Cardoso, Rozana A.

; Abras, Ana C.V.

; Silva, Antonio M.V.

; Dorneles, Camila C.

; Werle, Roberta W.

; Starke, Ana C.

; Ferreira, Juliana C.

; Plentz, Rodrigo D.M.

; Carvalho, Celso R.F.

Clinics

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2023, Volume 78 elocation 100180

Resumo: En | Texto: En | PDF: En

Abstract Background: Elderly patients are more susceptible to Coronavirus Disease-2019 (COVID-19) and are more likely to develop it in severe forms, (e.g., Acute Respiratory Distress Syndrome [ARDS]). Prone positioning is a treatment strategy for severe ARDS; however, its response in the elderly population remains poorly understood. The main objective was to evaluate the predictive response and mortality of elderly patients exposed to prone positioning due to ARDS-COVID-19. Methods: This retrospective multicenter cohort study involved 223 patients aged ≥ 65 years, who received prone position sessions for severe ARDS due to COVID-19, using invasive mechanical ventilation. The PaO2/FiO2 ratio was used to assess the oxygenation response. The 20-point improvement in PaO2/FiO2 after the first prone session was considered for good response. Data were collected from electronic medical records, including demographic data, laboratory/image exams, complications, comorbidities, SAPS III and SOFA scores, use of anticoagulants and vasopressors, ventilator settings, and respiratory system mechanics. Mortality was defined as deaths that occurred until hospital discharge. Results: Most patients were male, with arterial hypertension and diabetes mellitus as the most prevalent comorbidities. The non-responders group had higher SAPS III and SOFA scores, and a higher incidence of complications. There was no difference in mortality rate. A lower SAPS III score was a predictor of oxygenation response, and the male sex was a risk predictor of mortality. Conclusion: The present study suggests the oxygenation response to prone positioning in elderly patients with severe COVID-19-ARDS correlates with the SAPS III score. Furthermore, the male sex is a risk predictor of mortality.

https://doi.org/10.1016/j.clinsp.2023.100180

15.

NEURO-FUZZY MODELING AS SUPPORT FOR DECISION-MAKING IN THE PRODUCTION OF IRRIGATED CORIANDER UNDER MULCH IN THE SEMI-ARID REGION
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Gabriel Filho, Luís R. A.

; Rodrigueiro, Golbery R. O.

; Silva, Alexsandro O. da

; Almeida, Antonio V. R. de

; Cremasco, Camila P.

Engenharia Agrícola

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2023, Volume 43 Nº 2 elocation e20220208

Resumo: En | Texto: En | PDF: En

ABSTRACT Reducing water consumption by crops in semi-arid regions is an important factor for the sustainability of agriculture in these locations. In this sense, this study aims to evaluate the neuro-fuzzy inference method as a support for decision-making in irrigated coriander cultivation. The experiment was performed in two cultivation cycles in Pentecoste-CE, Brazil. The experiment was conducted in randomized blocks arranged in a split-plot design with five primary treatments, consisting of irrigation depths (50, 75, 100, 125, and 150% of the localized evapotranspiration, ETcloc), and five secondary treatments, consisting of different levels of bagana mulch (0, 25, 50, 75, and 100%, equivalent to 16 t ha−1). Neuro-fuzzy models with two input variables and eight output biometric variables were developed to evaluate growth (plant height, number of roots, and root length) and yield variables (productivity and shoot and root fresh and dry mass). In the first cycle, the best results occurred close to 55% ETcloc and between 40 and 50% of mulch; in the second cycle, water consumption returned results between 50 and 80% ETcloc. The fuzzy and multiple regression models showed MAE, MSE, and RMSE errors of 9, 22, and 10% lower, respectively. The neuro-fuzzy model might be a viable option for decision-making in irrigated crops, being able to optimize the use of natural resources and available water in semi-arid regions. The use of 55% of irrigation depth and a range of 40 to 50% of mulch can be a strategy for a higher water use efficiency.

https://doi.org/10.1590/1809-4430-eng.agric.v43n2e20220208/2023

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