Pesquisa | SciELO

Abstract Objectives: To review and provide evidence-based recommendations for the diagnosis and treatment of otosclerosis. Methods: Task force members were educated on knowledge synthesis methods, including electronic database search, review and selection of relevant citations, and critical appraisal of selected studies. Articles written in English or Portuguese on otosclerosis were eligible for inclusion. The American College of Physicians’ guideline grading system and the American Thyroid Association’s guideline criteria were used for critical appraisal of evidence and recommendations for therapeutic interventions. Results: The topics were divided into 2 parts: 1) Diagnosis – audiologic and radiologic; 2) Treatment – hearing AIDS, pharmacological therapy, stapes surgery, and implantable devices - bone-anchored devices, active middle ear implants, and Cochlear Implants (CI). Conclusions: The pathophysiology of otosclerosis has not yet been fully elucidated, but environmental factors and unidentified genes are likely to play a significant role in it. Women with otosclerosis are not at increased risk of worsening clinical condition due to the use of contraceptives or during pregnancy. Drug treatment has shown little benefit. If the patient does not want to undergo stapedotomy, the use of hearing aids is well indicated. Implantable systems should be indicated only in rare cases, and the CI should be indicated in cases of profound deafness.

https://doi.org/10.1016/j.bjorl.2023.101303

Influence of concrete strength on the distribution of bending moment in widened curved bridges
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Nascimento, Yngrid Rayane Freitas

; Silva Filho, José Neres da

; Rebouças, Arthur da Silva

; Barros, Rodrigo

; Nascimento Neto, Joel Araújo do

Revista IBRACON de Estruturas e Materiais

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2023, Volume 16 Nº 1 elocation e16105

Resumo: Pt En | Texto: Pt En | PDF: Pt | PDF: En

resumo: Esta pesquisa propõe analisar a distribuição de momentos fletores devido à carga móvel entre longarinas de pontes curvas de concreto armado que passaram por um processo de alargamento da superestrutura. Como principais conclusões foi constatado que a redistribuição de momentos é tanto mais significativa quanto mais elevada for a rigidez dos alargamentos. Ademais também foi observado que a redistribuição induzida pela variação da rigidez está condicionada à posição do carregamento móvel, porém, em geral, resultam na migração de esforços para os trechos mais rígidos, aliviando as longarinas originais. Constatou-se ainda que a variação da curvatura pouco altera a redistribuição de esforços induzida pelo aumento da rigidez no alargamento. Ademais, as divergências entre os resultados do MEF e do Método V-Load para os modelos com rigidez variável não divergiram significativamente daqueles obtidos nos modelos de rigidez constante. Por fim, os Fatores de Modificação (FM) mostraram-se mais sensíveis à variação do raio de curvatura do que à resistência do concreto nos alargamentos.

abstract: The study proposes to analyze the distribution of bending moment due to live load in curved bridges that have undergone a process of widening, considering the influence of concrete’s strength variation. The results show that the bending moment redistribution is more significant the higher the stiffness in the widenings. In addition, the redistribution induced by the variation of stiffness depends on the live load positioning but, generally, it results in the migration of bending moments to the stiffer regions, relieving the original girders. The curvature did not significantly alter the response induced by the stiffening of the widened segments. Also, the divergences found between the MEF and the V-load Method results for models with uniform and variable stiffness were similar. Finally, the Modification Factors (MF) proved to be more sensitive to the influence of curvature than to the concrete strength in the widenings.

https://doi.org/10.1590/s1983-41952023000100005

Vaccination coverage of triple viral and poliomyelitis in Brazil, 2011-2021: temporal trend and spatial dependency
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Palmieri, Isadora Gabriella Silva

; Lima, Lucas Vinícius de

; Pavinati, Gabriel

; Silva, José Arthur Paschoalotto

; Marcon, Sonia Silva

; Sato, Ana Paula Sayuri

; Magnabosco, Gabriela Tavares

Revista Brasileira de Epidemiologia

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2023, Volume 26 elocation e230047

Resumo: Pt En | Texto: Pt En | PDF: Pt | PDF: En

RESUMO Objetivo: Analisar a cobertura das vacinas tríplice viral e contra poliomielite, a tendência temporal e a dependência espacial em crianças de até um ano no Brasil, entre 2011 e 2021. Métodos: Estudo ecológico com dados secundários das taxas de cobertura vacinal (CV), disponibilizadas pelo Sistema de Informação do Programa Nacional de Imunização. A análise de tendência ocorreu pelo método joinpoint, segundo regiões geográficas, estimando a variação percentual anual (APC) e seu respectivo intervalo de confiança (IC95%). Foram construídos mapas coropléticos de distribuição por região de saúde e, posteriormente, verificou-se a dependência espacial pela estatística de Moran. Resultados: Entre 2011 e 2021, as coberturas vacinais apresentaram queda no Brasil, tanto para tríplice viral (APC: −6,4%; IC95%: −9,0; −3,8) quanto para poliomielite (APC: −4,5%; IC95% −5,5; −3,6). Houve declínio da cobertura de ambas as vacinas em todas as regiões geográficas ao longo dos anos de estudo, exceto no Sul e no Centro-Oeste para a vacina tríplice viral. Desde 2015, poucas regionais de saúde do país atingiram a CV adequada (≥95 a <120%). As regiões sanitárias do Norte e do Nordeste apresentaram clusters do tipo baixo-baixo na análise univariada para ambos os imunobiológicos. Conclusão: É premente considerar estudos como este para o planejamento de estratégias mais eficazes à imunização de crianças, sobretudo em áreas de maior queda. Desse modo, pode-se romper as barreiras do acesso à imunização, dada a heterogeneidade brasileira, e ampliar o acesso a informações fidedignas que aumentem a confiança na eficácia vacinal.

ABSTRACT Objective: To analyze the coverage of MMR and polio vaccines, the temporal trend and spatial dependence, in children up to one year of age in Brazil, between 2011 and 2021. Methods: Ecological study with secondary data on vaccination coverage rates, made available by the National Immunization Program Information System. Trend analysis was carried out using the joinpoint method, according to geographic regions, estimating the annual percentage change (APC) and its respective confidence interval (95%CI). Choropleth maps of distribution by health region were constructed and, subsequently, the spatial dependence was verified using Moran's statistics. Results: Between 2011 and 2021, vaccination coverage declined in Brazil, both for MMR (APC: −6.4%; 95%CI −9.0; −3.8) and for poliomyelitis (APC: −4. 5%; 95%CI −5.5; −3.6). There was a decline in coverage of both vaccines in all geographic regions over the years of the study, except in the South and Midwest for the MMR vaccine. Since 2015, few health regions in the country have achieved adequate vaccination coverage (≥95.0% to <120.0%). The North and Northeast health regions showed low-low clusters in the univariate analysis for both immunobiological. Conclusions: It is urgent to consider studies like this one for the planning of more effective strategies for immunizing children, especially in areas with higher falls. In this way, barriers to access to immunization can be broken, given Brazil's heterogeneity, and access to reliable information that increases confidence in vaccine efficacy can be expanded.

https://doi.org/10.1590/1980-549720230047

Progression of valve heart disease in a cohort of patients undergoing renal replacement therapy
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Tompson, Maria Eduarda Cavalcanti

; Pimentel, José Arthur Viana de Oliveira

; Silva, Manuella de Amorim

; Santos-Veloso, Marcelo Antônio Oliveira

; Lordsleem, Andrea Bezerra de Melo da Silveira

; Lima, Sandro Gonçalves de

Brazilian Journal of Nephrology

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2023, Nº ahead

Resumo: En Pt | Texto: En Pt | PDF: En | PDF: Pt

Abstract Introduction: Cardiovascular disease is an important cause of death among patients with chronic kidney disease (CKD). Valve calcification is a predictor of cardiovascular mortality and coronary artery disease. Objective: To assess heart valve disease frequency, associated factors, and progression in CKD patients. Methods: We conducted a retrospective study on 291 CKD patients at Hospital das Clínicas de Pernambuco. Inclusion criteria were age ≥ 18 with CKD and valve disease, while those on conservative management or with missing data were excluded. Clinical and laboratory variables were compared, and patients were categorized by dialysis duration (<5 years; 5–10 years; >10 years). Statistical tests, including chi-square, Fisher’s exact, ANOVA, and Kruskal-Wallis, were employed as needed. Simple and multivariate binary regression models were used to analyze valve disease associations with dialysis duration. Significance was defined as p < 0.05. Results: Mitral valve disease was present in 82.5% (240) of patients, followed by aortic valve disease (65.6%; 86). Over time, 106 (36.4%) patients developed valve disease. No significant association was found between aortic, pulmonary, mitral, or tricuspid valve disease and dialysis duration. Secondary hyperparathyroidism was the sole statistically significant factor for mitral valve disease in the regression model (OR 2.59 [95% CI: 1.09–6.18]; p = 0.031). Conclusion: CKD patients on renal replacement therapy exhibit a high frequency of valve disease, particularly mitral and aortic valve disease. However, no link was established between dialysis duration and valve disease occurrence or progression.

Resumo Introdução: Doenças cardiovasculares são uma causa significativa de morte em pacientes com Doença Renal Crônica (DRC). A calcificação valvar é preditor de mortalidade cardiovascular e doença arterial coronariana. Objetivo: Avaliar a frequência, fatores associados e progressão de valvopatias em pacientes com DRC. Métodos: Coorte retrospectiva com 291 pacientes ambulatoriais no Hospital das Clínicas de Pernambuco. Inclusão: ≥18 anos com DRC e valvopatia; exclusão: tratamento conservador ou dados incompletos. Variáveis clínicas e laboratoriais foram comparadas e categorizadas por tempo de terapia dialítica (TTD): <5 anos, 5–10 anos, >10 anos. Foram aplicados os testes Qui-quadrado, exato de Fisher, ANOVA, Kruskal-Wallis. Associação entre valvopatia e TTD foi avaliada por regressão binária. Significância foi definida como p < 0,05. Resultados: A valvopatia mitral foi encontrada em 82,5% (240) dos casos, seguida da aórtica (65,6%; 86). Houve progressão da doença valvar em 106 (36,4%) pacientes. Não houve associação entre valvopatias aórtica, pulmonar, mitral ou tricúspide e TTD. Hiperparatireoidismo secundário foi a única variável explicativa significativa na regressão para valvopatia mitral (OR 2,59 [IC95%: 1,09–6,18]; p = 0,031). Conclusão: Encontramos alta frequência de valvopatias, especialmente mitral e aórtica, aem pacientes com DRC. Não houve associação entre TTD e valvopatia.

https://doi.org/10.1590/2175-8239-jbn-2023-0036en

A fatal case of COVID-19-associated meningoencephalitis in a patient coinfected with influenza A
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Farias, Luís Arthur Brasil Gadelha

; Silva, Francisco José Cândido da

; Maia, Kelma Maria

; Cavalcante, Karene Ferreira

; Damasceno, Lisandra Serra

Revista do Instituto de Medicina Tropical de São Paulo

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2023, Volume 65 elocation e22

Resumo: En | Texto: En | PDF: En

ABSTRACT We report a case of COVID-19-associated meningoencephalitis with a fatal outcome in a male patient with concomitant influenza A, who had been hospitalized at the beginning of 2022, in the Northeastern region of Brazil. He died due to cardiopulmonary arrest after developing status epilepticus on the third day of hospitalization. The SARS-CoV-2 RNA was detected in cerebrospinal fluid and Influenza A was detected in the nasopharyngeal swab. Meningoencephalitis due to COVID-19 is a rare manifestation and physicians must be aware of this complication, mainly during the pandemic. In viral co-circulation situations, the possibility of respiratory coinfections should be remembered.

https://doi.org/10.1590/s1678-9946202365022

Occurrence and spatial distribution of native acai groves in high-production areas of the Amazon region
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Soares, Daniele Cristina de Bito Lima

; Lima, Herdjania Veras de

; Araújo, Suzana Romeiro

; Ramos, Robson José Carrera

; Rocha, Arthur José da Silva

Revista Ciência Agronômica

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2023, Volume 54 elocation e20218080

Resumo: En | Texto: En | PDF: En

ABSTRACT The floodplain forests of the Amazon estuary have undergone constant change over recent years, where management techniques, especially intensive management, have had an impact on the dynamics of the vegetation and land use. These changes can be monitored using satellite data. With this in mind, the aim of this study was to evaluate the dynamics of ground vegetation on the islands of Jarimbu, Mamangal, Itaboca, Mutirão and Buçu in the district of Igarapé-Miri, Pará, using images from the RapidEye and Planet satellites. The unsupervised ISODATA classification method was used, generating distinct classes of vegetation between each island. To evaluate the efficiency of the classification, an average of 200 random points were used, with another 30 points relating to the type of usage for each class. The Kappa index and overall precision were also analysed, in addition to calculating errors of omission and commission. Monitoring on a seven-year time scale using high-resolution satellites, a more than 50% increase in the Exposed Soil class was seen for the islands of Jarimbu, Mutirão and Itaboca, the latter responsible for an increase of more than 50% in the Urban Area class. On each of the five islands, the Alluvial class, representing the areas of açaí groves, has emerged over the last seven years, increasing in area at the expense of a reduction in the Arboreal class. In this respect, the confusion matrix showed a mean accuracy for the islands of ‘very good’, with a mean overall precision of 77.74%, and a mean Kappa index of 0.73, indicating strong agreement with the reference data and the classification.

https://doi.org/10.5935/1806-6690.20230039

Edible coating with microalgae and modified atmosphere packaging for post-harvest conservation of tomatoes
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Santos, Leônidas C dos

; Silva, Idelvan José da

; Santos, Arthur Vinicius D dos

; Sousa, Eder P da R

; Oliveira, Agda MF de

; Sousa, Valéria F de O

; Teodosio, Albert EM de M

; Onias, Elny A

; Araújo, Railene HCR

Horticultura Brasileira

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2023, Volume 41 elocation e2503

Resumo: En Pt | Texto: En Pt | PDF: En | PDF: Pt

ABSTRACT Tomato fruits are highly perishable. In this sense, adopting techniques to maintain and extend its shelf life is essential. Recent studies have used microalgae as an edible coating for fruit, as it is a nutrient-rich alternative and reduces fruit mass loss and respiration, delaying senescence. The aim of this study was to evaluate the application of microalgae-based coatings with or without the use of modified atmosphere packaging, polyvinyl chloride (PVC), in post-harvest tomato conservation. The design used was completely randomized, in a 4x2 factorial arrangement, with four coatings (no coating, coating composed of Spirulina platensis sp., Chlorella sp. and Scenedesmus sp.) and two conditions (with and without PVC), totalizing 8 treatments, with four replicates, consisting of one fruit each. Stored for 7 days at 10±2ºC and 55±5% UR and evaluated at harvest and on the last day of storage. The fruits coated with Chlorella sp. without PVC and Scenedesmus sp. associated with PVC, showed the lowest mass losses, representing a reduction of 73.79% and 78.47%, respectively, in relation to the control. In addition to mass loss, the levels of ascorbic acid (18.91 and 16.97 mg/100 g), citric acid (4.02 and 4.01), respectively, and the SS/AT ratio also stood out. The microalgae Chlorella sp. and Scenedesmus sp. can be used in coating ‘Santa Clara’ tomato fruits to maintain their physicochemical characteristics over 7 days of storage. The use of PVC film coating helped maintain these characteristics, reducing the perishability of the fruits.

RESUMO Os frutos do tomateiro têm alta perecibilidade havendo a necessidade da adoção de técnicas que mantenham e prolonguem sua vida útil pós-colheita. Estudos recentes têm utilizado microalgas como recobrimento comestível em frutos, por ser uma alternativa rica em nutrientes e reduzir perda de massa e respiração do fruto e assim retardar a senescência. Objetivou-se avaliar a aplicação de revestimentos a base de microalgas com ou sem o uso de embalagem com atmosfera modificada (policloreto de vinila) na conservação pós-colheita de tomate. O delineamento utilizado foi inteiramente casualizado, em arranjo fatorial 4x2, com quatro revestimentos (sem revestimento, revestimento com Spirulina platensis sp., Chlorella sp. e Scenedesmus sp.) e duas condições [com e sem PVC (policloreto de vinila)], totalizando 8 tratamentos, com quatro repetições, constituída por um fruto cada. Armazenados por 7 dias a 10±2ºC e 55±5% UR e avaliados na colheita e no último dia de armazenamento. Os frutos recobertos com Chlorella sp. sem o PVC e Scenedesmus sp. associado ao PVC, tiveram as menores perdas de massa, representando redução de 73,79% e 78,47%, respectivamente, em relação ao controle. Além da perda de massa, também tiveram destaque nos teores de ácido ascórbico (18,91 e 16,97 mg/100 g). As microalgas Chlorella sp. e Scenedesmus sp. podem ser utilizadas no revestimento de frutos do tomateiro ‘Santa Clara’ para manter suas características físico-químicas ao longo de 7 dias de armazenamento. A utilização do recobrimento com filme PVC auxilia na manutenção dessas características, diminuindo a taxa de perecibilidade dos frutos.

https://doi.org/10.1590/s0102-0536-2023-e2503

Atualização da Recomendação para Avaliação da Doença das Artérias Carótidas e Vertebrais pela Ultrassonografia Vascular: DIC, CBR, SBACV – 2023
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Albricker, Ana Cristina Lopes

; Freire, Claudia Maria Vilas

; Santos, Simone Nascimento dos

; Alcantara, Monica Luiza de

; Cantisano, Armando Luis

; Porto, Carmen Lucia Lascasas

; Amaral, Salomon Israel do

; Veloso, Orlando Carlos Glória

; Morais Filho, Domingos de

; Teodoro, José Aldo Ribeiro

; Petisco, Ana Cláudia Gomes Pereira

; Saleh, Mohamed Hassan

; Barros, Marcio Vinícius Lins de

; Barros, Fanilda Souto

; Engelhorn, Ana Luiza Dias Valiente

; Engelhorn, Carlos Alberto

; Nardino, Érica Patrício

; Silva, Melissa Andreia de Moares

; Biagioni, Luisa Ciucci

; Souza, Adriano José de

; Sarpe, Anna Karina Paiva

; Oliveira, Arthur Curtarelli de

; Moraes, Marcelo Rodrigo de Souza

; Francisco Neto, Miguel José

; Françolin, Peter Célio

; Rochitte, Carlos Eduardo

; Iquizli, Rogerio

; Santos, Alair Augusto Sarmet Moreira Damas dos

; Muglia, Valdair Francisco

; Naves, Bruno de Lima

Arquivos Brasileiros de Cardiologia

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2023, Volume 120 Nº 10 elocation e20230695

Resumo: En Pt | Texto: En Pt | PDF: En | PDF: Pt

https://doi.org/10.36660/abc.20230695

MIXED MODELS FOR NUTRIENTS PREDICTION IN SPECIES OF THE BRAZILIAN CAATINGA BIOME
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Abreu, Jadson Coelho de

; Silva, José Antônio Aleixo da

; Ferreira, Rinaldo Luiz Caraciolo

; Rocha, Samuel José Silva Soares da

; Tavares Júnior, Ivaldo da Silva

; Farias, Aline Araújo

; Villanova, Paulo Henrique

; Viana, Aguida Beatriz Travaglia

; Schettini, Bruno Leão Said

; Telles, Lucas Arthur de Almeida

; Silva, Arthur Araújo

Revista Árvore

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2023, Volume 47 elocation e4712

Resumo: En Pt | Texto: En Pt | PDF: En | PDF: Pt

ABSTRACT Nutrient prediction models applied to tree species from Brazilian Caatinga can be a crucial tool in understanding this biome. The study aimed to fit a mixed model to predict nitrogen (N), phosphorus (P), and potassium (K) content in tree species native to the Caatinga biome located in Floresta municipality, Pernambuco State – PE, Brazil. The following species were considered the area’s most important and evaluated in the present study: Poincianella bracteosa (Tul.) L.P.Queiroz, Mimosa ophtalmocentra Mart. ex Benth, Aspidosperma pyrifolium Mart, Cnidoscolus quercifolius (Mull. Arg.) Pax. & Hoffm, and Anadenanthera colubrina var. cebil (Griseb.) Altschul. Four trees, representing the average circumference in each diameter class, were harvested for NPK quantification. The Spurr model was evaluated for NPK prediction, and species inclusion as a random effect was significant (p > 0.05) in all models. The Spurr model with fixed and random effects presented better statistics than fixed-effect models in all parameters for all nutrients. Generated NPK predicting equations can be a handy tool to understand the impact of wood extraction over Caatinga’s biogeochemical cycles and guide forest management strategies in semi-arid regions of the world.

RESUMO Modelos de predição de nutrientes aplicados a espécies arbóreas da Caatinga brasileira podem ser uma ferramenta crucial para a compreensão do bioma. O estudo teve como objetivo ajustar um modelo misto para prever os teores de nitrogênio (N), fósforo (P) e potássio (K) em espécies arbóreas nativas do bioma Caatinga localizadas no município de Floresta, Pernambuco – PE, Brasil. As seguintes espécies foram as mais importantes da área e avaliadas no presente estudo: Poincianella bracteosa (Tul.) L.P.Queiroz, Mimosa ophtalmocentra Mart. ex Benth, Aspidosperma pyrifolium Mart, Cnidoscolus quercifolius (Mull. Arg.) Pax. & Hoffm e Anadenanthera colubrina var. cebil (Griseb.) Altschul. Quatro árvores, representando a circunferência média em cada classe de diâmetro, foram colhidas para quantificação de NPK. O modelo Spurr foi avaliado para predição de NPK e a inclusão de espécies como efeito aleatório foi significativa (p > 0,05) em todos os modelos. O modelo de Spurr com efeitos fixos e aleatórios apresentou estatísticas melhores que os modelos de efeito fixo em todos os parâmetros para todos os nutrientes. As equações de previsão de NPK geradas podem ser uma ferramenta útil para entender o impacto da extração de madeira sobre os ciclos biogeoquímicos da Caatinga e orientar estratégias de manejo florestal em regiões semiáridas do mundo.

https://doi.org/10.1590/1806-908820230000012

10.

Brazilian Society of Otology task force - Vestibular Schwannoma - evaluation and treatment
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Silva, Vagner Antonio Rodrigues

; Lavinsky, Joel

; Pauna, Henrique Furlan

; Vianna, Melissa Ferreira

; Santos, Vanessa Mazanek

; Ikino, Cláudio Márcio Yudi

; Sampaio, André Luiz Lopes

; Lopes, Paula Tardim

; Lamounier, Pauliana

; Maranhão, André Souza de Albuquerque

; Soares, Vitor Yamashiro Rocha

; Polanski, José Fernando

; Denaro, Mariana Moreira de Castro

; Chone, Carlos Takahiro

; Bento, Ricardo Ferreira

; Castilho, Arthur Menino

Brazilian Journal of Otorhinolaryngology

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2023, Volume 89 Nº 6 elocation 101313

Resumo: En | Texto: En | PDF: En

Abstract Objective: To review the literature on the diagnosis and treatment of vestibular schwannoma. Methods: Task force members were educated on knowledge synthesis methods, including electronic database search, review and selection of relevant citations, and critical appraisal of selected studies. Articles written in English or Portuguese on vestibular schwannoma were eligible for inclusion. The American College of Physicians’ guideline grading system and the American Thyroid Association’s guideline criteria were used for critical appraisal of evidence and recommendations for therapeutic interventions. Results: The topics were divided into 2 parts: (1) Diagnosis – audiologic, electrophysiologic tests, and imaging; (2) Treatment – wait and scan protocols, surgery, radiosurgery/radiotherapy, and systemic therapy. Conclusions: Decision making in VS treatment has become more challenging. MRI can diagnose increasingly smaller tumors, which has disastrous consequences for the patients and their families. It is important to develop an individualized approach for each case, which highly depends on the experience of each surgical team.

https://doi.org/10.1016/j.bjorl.2023.101313

11.

Vaccination coverage of triple viral and poliomyelitis in Brazil, 2011-2021: temporal trend and spatial dependency
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Palmieri, Isadora Gabriella Silva

; Lima, Lucas Vinícius de

; Pavinati, Gabriel

; Silva, José Arthur Paschoalotto

; Marcon, Sonia Silva

; Sato, Ana Paula Sayuri

; Magnabosco, Gabriela Tavares

Revista Brasileira de Epidemiologia

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2023, Volume 26 elocation e230047

Resumo: En Pt | Texto: En Pt | PDF: En | PDF: Pt

https://doi.org/10.1590/1980-549720230047

12.

Use and Applicability of Ozone Therapy in Clinical Practice in Dentistry: An Integrative Review
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Meira, Ana Beatriz Albuquerque

; Santos, Arthur Luna

; Lima, Cleiton Rone dos Santos

; Milhomens, Francisco Henrique Lima

; Araujo-Silva, Gabriel

; Cardoso, Maria do Socorro Orestes

; Travassos, Rosana Maria Coelho

; Filho, José Afonso Milhomens

International journal of odontostomatology

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Dez 2022, Volume 16 Nº 4 Páginas 468 - 474

Resumo: En Es | Texto: En Es | PDF: En | PDF: Es

ABSTRACT: Ozone is a colorless gas with a characteristic odor present in nature in the form of trivalent oxygen. In 2015, the Federal Council of Dentistry (CFO/Brazil) approved the use of ozone therapy and in 2018 the Ministry of Health (MS/Brazil) approved the application of Ozone Therapy as a Complementary Integrative Practice in the Unified Health System. Therefore, the objective of this study was to verify the applicability of ozone therapy in dental practice. This is an integrative literature review whose search was performed in the Medline/Pubmed, LILACS, SciElo, and Google Scholar databases. Studies published in the last 5 years in English, Portuguese or Spanish were eligible. After the search, 312 titles were found and after exclusion of duplicates and analysis of abstracts and full text, 13 articles were included in this review. The literature reports the application of ozone therapy in several areas in the treatment of acute and chronic diseases. As a mechanism of action, ozone has a direct antimicrobial effect, immunoregulation, antioxidant defenses, analgesic, and vasodilator effects. In dentistry, its applicability is mainly in preventive dentistry and as a complement in surgical procedur es, endodontic, and periodontal treatments.

RESUMEN: El ozono es un gas incoloro de olor característico presente en la naturaleza en forma de oxígeno trivalente. En 2015, el Consejo Federal de Odontología (CFO) aprobó el uso de la ozonoterapia y en 2018 el Ministerio de Salud aprobó la aplicación de la Ozonoterapia como Práctica Integrativa Complementaria en el Sistema Único de Salud. Por lo tanto, el objetivo de este estudio fue verificar la aplicabilidad de la ozonoterapia en la práctica odontológica. Esta es una revisión integrativa de la literatura cuya búsqueda se realizó en las bases de datos Medline/Pubmed, LILACS, SciElo y Google Scholar. Fueron elegibles los estudios publicados en los últimos 5 años en inglés, portugués o español. Después de la búsqueda, se encontraron 312 títulos y después de la exclusión de duplicados y análisis de resúmenes y texto completo, se incluyeron 13 artículos en esta revisión. La literatura reporta la aplicación de la ozonoterapia en varias áreas en el tratamiento de enfermedades agudas y crónicas. Como mecanismo de acción, el ozono tiene un efecto antimicrobiano directo, de inmunorregulación, defensas antioxidantes, efectos analgésicos y vasodilatadores. En odontología su aplicabilidad es principalmente en odontología preventiva y como complemento en procedimientos quirúrgicos, tratamientos endodónticos y periodontales.

13.

Extra-pituitary midline structural abnormalities associated with ectopic posterior pituitary detected on a new rapid MRI protocol (FAST1.2)
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Lyra, Arthur

; Guimarães, Daniel de Faria

; Meira, Altino Sá

; Peixoto, Guilherme Vieira

; Silva, Tatiane Sousa e

; Longui, Carlos Alberto

; Kochi, Cristiane

; Rocha, Antônio José da

Archives of Endocrinology and Metabolism

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Dez 2022, Volume 66 Nº 6 Páginas 831 - 836

Resumo: En | Texto: En | PDF: En

ABSTRACT Objective: Test if the MRI FAST1.2 protocol can detect extra-pituitary midline structural brain abnormalities in patients with ectopic posterior pituitary (EPP), and highlighting their radiological-laboratory correlations. Subjects and methods: Cross-sectional study of patients with EPP and control group. All individuals were submitted to FAST1.2, which combines the FAST1 protocol developed by our group with 3D T2DRIVE imaging. Results: We evaluated 36 individuals with EPP and 78 as control group. Pituitary stalk (PS) was identified in 7/36 patients in EPP group by FAST1, and in 24/36 patients in FAST1.2 (p < 0.001). FAST1 failed to detect PS in one individual in the control group, while the FAST1.2 defined the PS in all individuals. In EPP group, eleven had interhypothalamic adhesion (IHA), three septo-optic dysplasia, and one cerebellar malformation. We didn’t observe higher frequency of panhypopituitarism or developmental delay in patients with IHA. In control group, three had pars intermedia cysts, one hydrocephalus, and one hypothalamic hamartoma. Conclusions: FAST1.2 allows confident recognition of midline structural abnormalities, including the pituitary stalk and IHA, thereby making MRI acquisition faster and with no need for contrast administration. IHA could be associated with defects in neuronal migration, as occur in patients with EPP, with no clinical significance.

https://doi.org/10.20945/2359-3997000000505

14.

Prevalence of COVID-19 in medical school and residency in Porto Alegre, RS
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Silva, Gabriela Salzano

; Avila, Georgia Oliveira

; Lubianca, Fernanda Nascimento

; Lubianca, João Pedro Neves

; Michelon, Victória Marques de Medeiros

; Kalil, Diogo Pereira

; Maestri, Lorenzo Feldman

; Lengler, Arthur Dementshuk

; Lima, Guilherme Pereira

; Lubianca Neto, José Faibes

Revista da Associação Médica Brasileira

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Fev 2022, Volume 68 Nº 2 Páginas 206 - 211

Resumo: En | Texto: En | PDF: En

SUMMARY OBJECTIVE: A multicentric, cross-sectional study was carried out to determine the prevalence and risk factors for Coronavirus disease 2019 in medical students and residents from four universities and affiliated hospitals in Brazil. METHODS: A survey about contamination risk and symptoms was sent to all participants through email and WhatsApp. Prevalence was measured by the self-report of positive polymerase chain reaction or serological test. Univariate and multivariate analyses were performed, and odds ratio and 95% confidence interval were calculated. RESULTS: Prevalence of infection by Sars-CoV-2 was 14.9% (151/1011). The disease was more prevalent in residents and interns than in undergraduate students. Contact with an infected relative outside the hospital or with colleagues without using personal protective equipment was associated with higher contamination. Contact with patients without wearing goggles and higher weekly frequency of contact were the two factors independently associated with the infection by Coronavirus disease 2019 in the multivariate analysis. CONCLUSIONS: Medical students, interns, and residents have a higher prevalence of Coronavirus disease 2019 than the general population, in which the last two groups are significantly at higher risk. Contacting patients at a higher weekly frequency increases the risk for infection. The use of goggles should be reinforced when contacting patients.

https://doi.org/10.1590/1806-9282.20211114

15.

Curved bridges live load bending moment distribution using straight and curved girders
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Rebouças, Arthur da Silva

; Silva Filho, José Neres da

; Barros, Rodrigo

; Nascimento, Yngrid Rayane Freitas

; Coutinho, Pedro Mitzcun

Revista IBRACON de Estruturas e Materiais

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2022, Volume 15 Nº 2 elocation e15208

Resumo: Pt En | Texto: Pt En | PDF: Pt | PDF: En

resumo: o presente estudo foca na análise paramétrica comparativa de pontes curvas utilizando utilizando longarinas retas e curvas pré-moldadas. As análises foram baseadas na distribuição transversal de momento fletor para a longarinas, na variação da curvatura da ponte e na relação desses parâmetros com os resultados obtidos em uma ponte reta. Foram desenvolvidos FEM 3D models com restrições nas posições transversais da carga-móvel e com dois tipos diferentes de modelos de carga: HL-93 e NBR 7187. Os resultados da análise paramétrica foram determinados utilizando o Fator de Modificação (FM) e o Fator de Distribuição de Momento Fletor (FDMF), calculadas a partir da análise estrutural de cada modelo na posição longitudinal do meio do vão. No âmbito global, contatou-se um aumento do momento fletor total nos modelos de ponte curva em relação à reta. Nos exemplos estudados, quanto maior o raio de curvatura, maior foi o momento fletor máximo no meio do vão da ponte. O valor de FM varia linearmente. Para as longarinas externas o FM aumenta com o aumento do L/R, já para as internas, o FM diminui com o aumento do L/R. Além disso, foi comprovada a ocorrência de “Load Shift” diferente do comportamento de corpo rígido, tendo em vista a variação diferenciada de momento fletor para a longarina externa G1 em relação a sua adjacente G2. Constatou-se uma diferença considerável de comportamento estrutural entre as longarinas retas e curvas, tendo em vista que nas SG ocorreu uma diferença significativa de FDMF entre a longarina G1 e a G2 para todas as curvaturas, o que não ocorreu para as CG. Para L/R=0.6, observou-se uma diferença de 17.8% no FDMF entre as longarinas G1 e G2 retas, já nas longarinas curvas, a diferença foi de apenas 6.6%.

abstract: The present study focuses on comparative parametric analysis of curved precast concrete bridges using straight and curved I-girders. The live load bending moment distribution for girders was studied using the bridge curvature and its relationship with the results obtained for a straight bridge. FEM 3D models were developed with restrictions on the transverse live load positions and with two different load models types: HL-93 (AASHTO) and TB-450 (NBR 7188, 2013). The parametric analysis results were calculated using the Modification Factor (MF) and the Bending Moment Distribution Factor (BMDF), calculated from the structural analysis of each model at the midspan. Globally, an increase was found in the total bending moment for the curved bridge models in relation to the straight bridge. In the examples herein studied, the larger the bending radius, the larger the maximal bending moment in the bridge center. For the external girders, the MF increases with the increase of the L/R. For the internal ones, the MF decreases with the increase of the L/R. In addition, the occurrence of “Load Shift” was different from the rigid body behavior, for there was demonstrated a different bending moment variation between external girder (G1) in relation to its adjacent (G2). Therefore, the structural behavior of straight (SG) and curved girders (CG) was analyzed, revealing that, in the SG, a significant gap occurred in the BMDF between G1 and G2 girders for all curvatures. For L/R = 0.6, it caused a difference of 17.8% in the BMDF between the G1 and G2 girders, while on the curved girders, a difference of only 6.6% was found.

https://doi.org/10.1590/s1983-41952022000200008 67 downloads

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