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RESUMEN Objetivo: Validar lista de verificación para el baño seguro en pacientes críticos. Métodos: Estudio metodológico y cuantitativo. Se elaboró una lista de verificación para baño seguro en paciente crítico compuesta por 41 ítems, que fue sometida al proceso de validación aparente y de contenido, evaluada por 11 jueces, y confiabilidad interobservadores. Para el análisis de confiabilidad, el instrumento fue aplicado en 54 procedimientos de baño en el lecho en UTI; utilizados las pruebas de Kappa e ICC. Resultados: En la validación aparente y de contenido, fueron realizados ayustes conforme sugestiones de los jueces. Los valores de Kappa variaron de moderado a casi perfecto (0,462 a 0,962); y, en algunos ítems, hubo 100% de concordancia; la confiabilidad del instrumento fue excelente (ICC = 0,962). Conclusión: El instrumento se demostró confiable y de fácil aplicación. Su utilización contribuirá para el baño en el lecho seguro y subsidiará intervenciones que objetiven aumentar la calidad asistencial.

ABSTRACT Objective: To validate a checklist for safe bathing in critically ill patients. Methods: This is a methodological and quantitative study. Researchers developed a checklist for safe bathing in critically ill patients consisting of 41 items, which were submitted to the apparent and content validation process, evaluated by eleven judges, and interobserver reliability. For reliability analysis, the instrument was applied in 54 bed bath procedures in the ICU; Kappa and CHF tests were used. Results: In the apparent and content validation, adjustments were made according to the judges’ suggestions. Kappa values ranged from moderate to almost perfect (0.462 to 0.962), and, in some items, there was 100% agreement; the reliability of the instrument was excellent (ICC = 0.962). Conclusion: The instrument proved to be dependable and easy to apply. Its use will contribute to safe bed bathing and subsidize interventions aimed at increasing the quality of care.

RESUMO Objetivo: Validar uma lista de verificação para o banho seguro em pacientes críticos. Métodos: Estudo metodológico e quantitativo. Elaborou-se uma lista de verificação para banho seguro no paciente crítico composta por 41 itens, que foi submetida ao processo de validação aparente e de conteúdo, avaliada por 11 juízes, e confiabilidade interobservadores. Para a análise de confiabilidade, o instrumento foi aplicado em 54 procedimentos de banho no leito em UTI; utilizaram-se os testes de Kappa e ICC. Resultados: Na validação aparente e de conteúdo, foram realizados ajustes conforme sugestões dos juízes. Os valores de Kappa variaram de moderado a quase perfeito (0,462 a 0,962); e, em alguns itens, houve 100% de concordância; a confiabilidade do instrumento foi excelente (ICC = 0,962). Conclusão: O instrumento demonstrou-se confiável e de fácil aplicação. Sua utilização contribuirá para o banho no leito seguro e subsidiará intervenções que visem aumentar a qualidade assistencial.

https://doi.org/10.1590/0034-7167-2023-0135

Factors associated with bacterial vaginosis in women with homosexual, bisexual and heterosexual practices
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Ignacio, Mariana Alice de Oliveira

; Buesso, Thayná Santos

; Morales, Julia Andrade Pessoa

; Silva, Mariana de Castro

; Silva, Marcia Guimaraes da

; Duarte, Marli Teresinha Cassamassimo

Brazilian Journal of Infectious Diseases

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2023, Volume 27 Nº 3 elocation 102760

Resumo: En | Texto: En | PDF: En

Abstract Background The factors associated with bacterial vaginosis in women with homosexual, bisexual and heterosexual practices are still poorly explored. Thus, the aim of this study was to analyze the factors associated with bacterial vaginosis in women with different sexual practices. Methods Cross-sectional study that included 453 women, 149 Women with Homosexual practice (WSW); 80 bisexual Women (WSWM) and 224 Women with heterosexual practice (WSM). The diagnosis of bacterial vaginosis was performed by microscopic examination of the vaginal smears stained by Gram method and classified according to the Nugent et al. (1991) score. Data analysis was performed by Cox multiple regression. Results Bacterial vaginosis was associated to years of education among WSW (0.91 [95% CI 0.82‒0.99]; p= 0.048) and non-white skin color (2.34 [95% CI 1.05‒5.19]; p= 0.037) between WSWM. Changing partners in the last 3-months (2.09 [95% CI 1.14‒3.82]; p= 0.017), inconsistent use of condoms (2.61 [95% CI 1.10‒6.20]; p= 0.030) and positive diagnosis of Chlamydia trachomatis (2.40 [95% CI 1.01‒5.73]; p= 0.048) were associated with bacterial vaginoses only in WSH. Conclusions The factors associated to bacterial vaginosis differ between different sexual practices, suggesting that the type of sexual partner may influence the risk of developing this classic dysbiosis.

https://doi.org/10.1016/j.bjid.2023.102760

Factors associated with Trichomonas vaginalis infection in reproductive-aged women attending cervical screening in southeast of Brazil
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Pinto, Gabriel Vitor da Silva

; Bolpet, Aline do Nascimento

; Martin, Laura Fernandes

; Moço, Natália Prearo

; Ramos, Bruna Ribeiro de Andrade

; Silva, Mariana de Castro

; Duarte, Marli Teresinha Casamassimo

; Tristão, Andréa da Rocha

; Silva, Márcia Guimarães da

; Marconi, Camila

Brazilian Journal of Infectious Diseases

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2023, Volume 27 Nº 4 elocation 102794

Resumo: En | Texto: En | PDF: En

ABSTRACT Background: Sexually Transmitted Infections (STIs) can be caused by viruses, bacteria, and parasites. The World Health Organization estimated more than 300 million new global cases of curable STIs among individuals of reproductive age. Infection by Trichomonas vaginalis is one of the most prevalent curable STL Despite the current treatments available, the diagnosis of T. vaginalis can be difficult, and the resistance to the treatment increased concern for the healthcare system. Objectives: The aim of this study was to determine the prevalence and factors associated with Trichomonas vaginalis infection among women of reproductive age attending community-based services for cervical screening. Patients and methods: A total of 1477 reproductive-aged women attending 18 Primary Health Care Units in Botucatu, Brazil, from September to October 2012, were enrolled. A structured questionnaire was used for individual face-to-face interviews for obtaining data on sociodemographic, gynecologic, and obstetrics history, sexual and hygiene practices, among others. Cervicovaginal samples were obtained for detection of T. vaginalis by culture using Diamond's medium and microscopic vaginal microbiota classification according to Nugent. A multivariable logistic regression analysis was carried out to estimate Odds Ratios (OR) and 95% Confidence Intervals (95% CI) for the association between participants’ sociodemographic, behavioral factors, and clinical factors with T. vaginalis infection. Results: Median age of study participants was 33 years (ranging from 18 to 50). The overall prevalence of T. vaginalis infection was 1.3% (n = 20). Several factors were independently associated with T. vaginalis infection, such as self-reporting as black or Pardo for ethnicity (OR = 2.70; 95% CI 1.03–7.08), smoking (OR=3.18; 95% CI 1.23–8.24) and having bacterial vaginosis (OR = 4.01; 95%CI = 1.55–10.38) upon enrollment. A protective effect of higher educational level (having high school degree) was observed (OR = 0.16; 95% CI 0.05–0.53). Conclusions: Our data suggest that screening programs to correctly detect T. vaginalis infection can be helpful to guide prevention strategies to the community. Our study supports an association between abnormal vaginal microbiota and T. vaginalis infection.

https://doi.org/10.1016/j.bjid.2023.102794

Contribution of public oral pathology services to the diagnosis of oral and oropharyngeal cancer in Brazil
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LOUREDO, Brendo Vinicius Rodrigues

; CURADO, Maria Paula

; PENAFORT, Paulo Victor Mendes

; DE ARRUDA, José Alcides Almeida

; ABREU, Lucas Guimarães

; MESQUITA, Ricardo Alves

; PINTO-JÚNIOR, Décio dos Santos

; ABRAHÃO, Aline Corrêa

; ANDRADE, Bruno Augusto Benevenuto de

; AGOSTINI, Michelle

; MORAES, Renata Mendonça

; ANBINDER, Ana Lia

; DOURADO, Pedro Henrique Silva

; SANTOS, Teresa Cristina Ribeiro Bartholomeu dos

; PIRES, Fábio Ramoa

; BORDIGNON, Natalia Cristina Trentin

; GONDAK, Rogério Oliveira

; DE OLIVEIRA, Marcia Gaiger

; CARRARD, Vinicius Coelho

; MARTINS, Manoela Domingues

; SOUSA-NETO, Sebastião Silvério

; ARANTES, Diego Antônio Costa

; MENDONÇA, Elismauro Francisco

; CIESLAK-SANCHES, Silvia Roberta

; ANTUNES, Daniella Moraes

; AMARAL-SILVA, Gleyson Kleber do

; MANIERI, Patricia Rubia

; RAMALHO, Luciana Maria Pedreira

; DOS SANTOS, Jean Nunes

; LEONEL, Augusto César Leal da Silva

; PEREZ, Danyel Elias da Cruz

; VERHEUL, Hannah Carmem Carlos Ribeiro Silva

; BARROSO, Keila Martha Amorim

; RODRIGUES, Flávia Luiza Santos

; GONZAGA, Amanda Katarinny Goes

; FERNANDES, Romana Renery

; DE SOUZA, Lélia Batista

; SOUZA, Lucas Lacerda de

; PONTES, Flávia Sirotheau Corrêa

; PONTES, Hélder Antônio Rebelo

; SILVA, Caroline Alfaia

; CÂMARA, Jeconias

; LIBÓRIO-KIMURA, Tatiana Nayara

; SANTOS-SILVA, Alan Roger

; LOPES, Márcio Ajudarte

; ALMEIDA, Oslei Paes de

; ROMAÑACH, Mário José

; VARGAS, Pablo Agustin

Brazilian Oral Research

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2023, Volume 37 elocation e126

Resumo: En | Texto: En | PDF: En

Abstract This study aimed to evaluate the contribution of oral and maxillofacial pathology laboratories (OMPLs) in Brazilian public universities to the diagnosis of lip, oral cavity, and oropharyngeal squamous cell carcinoma (SCC). A cross-sectional study was performed using biopsy records from a consortium of sixteen public OMPLs from all regions of Brazil (North, Northeast, Central-West, Southeast, and South). Clinical and demographic data of patients diagnosed with lip, oral cavity, and oropharyngeal SCC between 2010 and 2019 were collected from the patients’ histopathological records. Of the 120,010 oral and maxillofacial biopsies (2010-2019), 6.9% (8,321 cases) were diagnosed as lip (0.8%, 951 cases), oral cavity (4.9%, 5,971 cases), and oropharyngeal (1.2%, 1,399 cases) SCCs. Most cases were from Brazil’s Southeast (64.5%), where six of the OMPLs analyzed are located. The predominant profile of patients with lip and oral cavity SCC was Caucasian men, with a mean age over 60 years, low schooling level, and a previous history of heavy tobacco consumption. In the oropharyngeal group, the majority were non-Caucasian men, with a mean age under 60 years, had a low education level, and were former/current tobacco and alcohol users. According to data from the Brazilian National Cancer Institute, approximately 9.9% of the total lip, oral cavity, and oropharyngeal SCCs reported over the last decade in Brazil may have been diagnosed at the OMPLs included in the current study. Therefore, this data confirms the contribution of public OMPLs with respect to the important diagnostic support they provide to the oral healthcare services extended by the Brazilian Public Health System.

https://doi.org/10.1590/1807-3107bor-2023.vol37.0126

Intestinal microbiome characterization of adult Brazilian men with psoriasis compared to omnivore and vegetarian controls
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Polo, Tatiana Cristina Figueira

; Lai, Mariana Righetto de Ré

; Miot, Luciane Donida Bartoli

; Bento, Giovana Fernanda Cosi

; Silva, Márcia Guimarães da

; Marques, Silvio Alencar

; Miot, Hélio Amante

Anais Brasileiros de Dermatologia

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2023, Volume 98 Nº 5 Páginas 635 - 643

Resumo: En | Texto: En | PDF: En

Abstract Background Psoriasis is a chronic inflammatory disease associated with systemic inflammation and comorbidities. Changes in the composition of the intestinal microbiome are involved in the pathogenesis of inflammatory diseases and metabolic syndrome. Characterizing the intestinal microbiome of patients with psoriasis may be relevant for the understanding of its clinical course and comorbidity prevention. Objective To characterize the intestinal microbiome of men with psoriasis compared to omnivore and vegetarian controls (without psoriasis). Method Cross-sectional study of 42 adult males: 21 omnivores with psoriasis; and controls: 14 omnivores and 7 vegetarian individuals. The characterization of the intestinal microbiome was performed by metagenomic analysis. Serum levels of lipopolysaccharide-binding protein (LPB) and C-reactive protein (CRP) were evaluated. Results The groups differed from each other regarding nutritional aspects and microbiome; individuals with psoriasis had a higher consumption of protein and lower consumption of fibers. Levels of LPB, CRP, and the Firmicutes/Bacteroidetes ratio were higher in the group with psoriasis than in the vegetarian group (p < 0.05). The genera Prevotella, Mogibacterium, Dorea, Bifidobacterium and Coprococcus, differed in the group with psoriasis compared to vegetarians; the genera Mogibacterium, Collinsella and Desulfovibrio differed from omnivores. A microbiome pattern linked to psoriasis (plsPSO) was identified, which was associated with higher LPB levels (rho = 0.39; p = 0.02), and lower dietary fiber intake (rho = −0.71; p < 0.01). Study limitations Only adult men were evaluated. Conclusion A difference was identified in the intestinal microbiome of adult men with psoriasis when compared to healthy omnivores and vegetarian controls. The identified microbiome pattern was correlated with dietary fiber intake and serum levels of LPB.

https://doi.org/10.1016/j.abd.2022.08.008

ENERGIAS RENOVÁVEIS: O PARQUE EÓLICO DE SÃO CRISTÓVÃO, MUNICÍPIO DE AREIA BRANCA (RN) - BRASIL
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SILVA FARIAS, MÁRCIA REGINA FARIAS DA

; SILVA, ÍTALO HENRIQUE MONTEIRO DA

; CARVALHO, RODRIGO GUIMARÃES DE

GOT, Revista de Geografia e Ordenamento do Território

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Dez 2021, Nº 22 Páginas 111 - 139

Resumo: Pt En | Texto: Pt En | PDF: Pt | PDF: En

RESUMO O Brasil tem elevado seu potencial de aproveitamento de fontes renováveis de energia, principalmente empreendimentos eólicos que vêm se expandindo no mercado nacional. O ganho de espaço na matriz nacional possibilitou a corrida eólica, que, por sua vez, ocasionou problemas socioambientais em decorrência da instalação dos parques eólicos. Esta pesquisa objetivou identificar as mudanças ocorridas na comunidade pesqueira de São Cristóvão, localizada no município de Areia Branca, Rio Grande do Norte (RN), Brasil, a partir da introdução do parque eólico. Adotou-se uma abordagem mista e, para a coleta de dados, fez-se uso de visitas in loco associadas à análise de documentos, realização de entrevistas e aplicação de questionários semiestruturados, que foram catalogados e analisados com o auxílio do programa Statistical Package for the Social Sciences (SPSS), versão 20.0. Participaram do estudo 80 (oitenta) pessoas. Como resultado, foi possível identificar que o processo de instalação do parque eólico ocorreu sem uma participação expressiva da comunidade e há ausência de um diálogo aprofundado entre a empresa e a população inserida nas proximidades do parque eólico. Verificou-se que o impacto na economia local após a instalação do empreendimento é inexpressivo, segundo os entrevistados. Constataram-se conflitos socioambientais relacionados à posse da terra, e, face a essas questões, a comunidade expressa desconfianças em relação aos parques eólicos na região.

ABSTRACT Brazil has increased its potential to take advantage of renewable energy sources, mainly wind farms that have been expanding in the national market. The gain of space in the national matrix enabled the wind race, which in turn caused socio-environmental problems as a result of the installation of wind farms. In this direction, this research aimed to identify the changes that occurred in the fishing community of São Cristóvão, located in the municipality of Areia Branca, Rio Grande do Norte (RN), Brazil, from the introduction of the wind farm. A mixed approach was adopted and for data collection, on-site visits associated with photographic record analysis, semi-structured questionnaire applications with open and closed questions were used, cataloged and analyzed with the aid of the Statistical Package for the Social program Sciences (SPSS) version 20.0. 80 (eighty people) participated in the study. As a result, it was possible to identify that the wind farm installation process took place without significant community participation and the absence of an in-depth dialogue between the company and the population located in the vicinity of the wind farm. It was found that the impact on the local economy, after the installation of the enterprise is insignificant, according to the interviewees. It was found that socioenvironmental conflicts related to land tenure and faced with these issues, the community expresses distrust in relation to wind farms in the region.

https://doi.org/10.17127/got/2021.22.005 17 downloads

Toxicity of Carnoy's solution toward human keratinocytes: an in vitro study
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Pinto Júnior, Aécio Abner Campos

; Viana, Karolina Skarlet Silva

; Abreu, Lucas Guimarães

; Nascentes, Clésia Cristina

; Diniz, Ivana Márcia Alves

; Mesquita, Ricardo Alves

; Bernardes, Vanessa Fátima

Brazilian Oral Research

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2021, Volume 35 elocation e124

Resumo: En | Texto: En | PDF: En

Abstract: The present study aimed to characterize the chemical elements and cytotoxicity of Carnoy's solution (CS) by comparing two different trademarked products (one Brazilian [NCS] and another imported [ICS]) using inductively coupled plasma mass spectrometry (ICP-MS) and human keratinocyte (HaCaT) cultures. For performing ICP-MS, the solutions were diluted according to calibration curves, and the chemical elements were analyzed with a spectrometer. HaCaT cells were exposed to CS concentrations ranging from 0.10% to 20% for 3 or 5 min. Cell viability was evaluated immediately (T0), 24 h (T1), and 7 days (T2) after exposure to CS using 3-(4,5-dimethylthiazol-2-yl)-2, 5-diphenyl-tetrazolium bromide (MTT) reduction assay. Data were analyzed using a t-test for ICP-MS and analysis of variance followed by Tukey's post-hoc test for MTT assay, both considering statistical significance at p<0.05. ICP-MS results revealed that ICS presented significantly lower concentrations of 12 chemical elements than NCS. The results of MTT assay revealed that at T0, ICS was more cytotoxic than NCS regardless of the time of exposure (p < 0.05). At T1, the only difference between the groups was at a concentration of 0.10% after 5 min of exposure. At T2, at a concentration of 0.5%, ICS resulted in a significant reduction in cell viability compared to NCS (p < 0.05). Thus, the results showed that ICS was more cytotoxic than NCS. Collectively, our findings suggest that the individual compositions of different CS formulations should be investigated.

https://doi.org/10.1590/1807-3107bor-2021.vol35.0124 1 downloads

Pollen Spectrum of Honey from the Bee Melipona subnitida Ducke (1910) in Restinga in Maranhão State
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Diniz, Maira Rodrigues

; Silva, Albeane Guimarães

; Carreira, Léa Maria Medeiros

; Almeida Jr., Eduardo Bezerra de

; Rêgo, Márcia Maria Corrêa

Floresta e Ambiente

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2021, Volume 28 Nº 2 elocation e20200068

Resumo: En | Texto: En | PDF: En

Abstract The study aimed to analyze the honey of Melipona subnitida to identify the plants visited by these bees in colonies installed in a restinga vegetation in Maranhão state. Honey was collected monthly from July/2017 to June/2018. The honey samples were submitted to the acetolysis method and the pollen grains were analyzed qualitatively and quantitatively. The pollen analysis of honey resulted in 54 pollen types and 26 families. The largest pollen variety was registered in Fabaceae. Quantitative analyzes of pollen grains in honey samples revealed that three were monofloral, in July/2017 with Avicennia germinans honey and December/2017 and January/2018 with Copaifera martii honey. In the other months, the heterofloral honeys. Melipona subnitida proved to be general in food gathering. Knowing the flora used by M. subnita contributes to the meliponiculturists to improve the handling of the colonies, the increase and quality in the production of honey.

https://doi.org/10.1590/2179-8087-floram-2020-0068 388 downloads

Effectiveness of the serious game for learning in nursing: systematic review
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Nascimento, Kleiton Gonçalves do

; Ferreira, Maria Beatriz Guimarães

; Felix, Márcia Marques dos Santos

; Nascimento, Juliana da Silva Garcia

; Chavaglia, Suzel Regina Ribeiro

; Barbosa, Maria Helena

Revista Gaúcha de Enfermagem

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2021, Volume 42 elocation e20200274

Resumo: Pt En Es | Texto: Pt En Es | PDF: Pt | PDF: En | PDF: Es

RESUMO Objetivo Identificar a eficácia do serious game na melhoria dos resultados de aprendizagem em comparação às diferentes estratégias de ensino utilizadas na educação de estudantes de enfermagem. Método Revisão sistemática, realizada de julho/2019 a maio/2020, na PubMed®, Scopus, CINAHL, Web of Science e LILACS. Incluíram-se estudos de delineamento experimental e quasi-experimental, sem delimitação de recorte temporal, voltados a estudantes de enfermagem, que abordassem o uso do serious game como principal estratégia de ensino comparada com outros métodos pedagógicos. Resultados Foram incluídos seis artigos, os quais compararam o serious game com estratégias tradicionais e ativas de ensino e aprendizagem (aula expositiva, leitura de textos e simulação). Os estudos foram considerados de qualidade moderada, com escore médio de 12,83. Os estudantes de enfermagem submetidos ao serious game apresentaram melhores resultados de aprendizagem. Conclusão O serious game demonstrou-se mais efetivo para aprendizagem em enfermagem quando comparado a outras estratégias de ensino.

ABSTRACT Objective To identify the effectiveness of the serious game in improving learning outcomes compared to the different teaching strategies used in the education of nursing students. Method Systematic review, conducted from July 2019 to May 2020, at PubMed®, Scopus, CINAHL, Web of Science and LILACS. Studies of experimental and quasi-experimental design were included, with no delimitation of time frame, aimed at nursing students, who approached the use of the serious game as the main teaching strategy compared with other pedagogical methods. Results Six articles were included, which compared the serious game with traditional and active teaching and learning strategies (expository class, text reading and simulation). The studies were considered of moderate quality, with an average score of 12.83. Nursing students submitted to the serious game showed better learning results. Conclusion The serious game proved to be more effective for learning in nursing when compared to other teaching strategies.

RESUMEN Objetivo Identificar la efectividad del juego serio em la mejora de los resultados del aprendizaje en comparación con las diferentes estrategias de enseñanza utilizadas en la educación de los estudiantes de enfermería. Métodos Revisión sistemática, realizada de julio de 2019 a mayo de 2020, en PubMed®, Scopus, CINAHL, Web of Science y LILACS. Se incluyeron estudios de diseño experimental y cuasiexperimental, sin delimitación temporal, dirigidos a estudiantes de enfermería, quienes abordaron el uso del juego serio como principal estrategia de enseñanza frente a otros métodos pedagógicos. Resultados Se incluyeron seis artículos, que compararon el juego serio con estrategias de enseñanza y aprendizaje tradicionales y activas (clase expositiva, lectura de textos y simulación). Los estudios se consideraron de calidad moderada, con una puntuación media de 12,83. Los estudiantes de enfermería sometidos al juego serio mostraron mejores resultados de aprendizaje. Conclusión El juego serio demostró ser más efectivo para aprendizaje en enfermería en comparación con otras estrategias de enseñanza.

https://doi.org/10.1590/1983-1447.2021.20200274 303 downloads

10.

Carious lesions recurrence in children with developmental disabilities: a longitudinal study
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CASTILHO, Lia Silva de

; DINIZ, Ivana Márcia Alves

; SANTOS, Bruno Pereira dos Reis

; LAGES, Frederico Santos

; CRUZ, Alex Júnio Silva da

; ABREU, Mauro Henrique Nogueira Guimarães

Brazilian Oral Research

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2021, Volume 35 elocation e071

Resumo: En | Texto: En | PDF: En

Abstract This study investigated the factors associated with new carious lesions in one-to five-year-old children with developmental disabilities. This was a retrospective cohort that evaluated 64 dental charts of individuals with caries or fillings in their first dental appointment. The dependent variable was the occurrence of a new carious lesion or restoration. Gender, age, mother’s education, sugar consumption, oral hygiene, mouth breathing, reports of xerostomia, gingival status, use of psychotropic drugs, use of asthma drugs, history of asthma, bronchitis, reflux or seizures and having at least one sibling were covariates. Cox proportional hazards regression model was used to estimate the raw and adjusted hazard ratios with their respective 95% confidence interval. The average time that individuals remained free of dental caries/restoration was 79.49 months (95%CI: 64.37 to 92.61). Increase in sucrose consumption increased the rate of caries recurrence (HR = 1.16; 95%CI: 1.04 to 1.30). Individuals who had poor oral hygiene had higher rate of new dental caries (HR = 3.88; 95%CI: 1.22 to 12.37) compared to those with good oral hygiene. The presence of mouth breathing decreased the rate of recurrence of the disease when compared to the nasal breathing (HR = 0.32; 95%CI: 0.15 to 0.70). Oral health-related behaviors and nasal respiration influenced the rate of dental caries recurrence in individuals with developmental disabilities.

https://doi.org/10.1590/1807-3107bor-2021.vol35.0071 66 downloads

11.

Standardization of organoid culture for evaluation of melanogenesis induced by UVB, UVA and visible light,
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Olivatti, Thainá Oliveira Felicio

; Alcantara, Giovana Piteri

; Lemos, Ana Cláudia Cavalcante Espósito

; Silva, Márcia Guimarães da

; Miot, Hélio Amante

Anais Brasileiros de Dermatologia

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Fev 2020, Volume 95 Nº 1 Páginas 46 - 51

Resumo: En | Texto: En | PDF: En

Abstract Background: Organoid cultures are primary cultures that maintain architectural characteristics and the relationships between cells, as well as the extracellular matrix. They are alternatives for pathophysiological or therapeutic investigation rather than animal and in vitro tests. Objective: Development of a cutaneous organoid culture model, aiming at the study of radiation-induced melanogenesis. Method: A validation study, which involved biopsies of the skin of the back of the adult ear. One sample was irradiated with different doses of UVB, UVA, or visible light (VL); the other was maintained in the dark for 72 h. The viability of the tissues was evaluated from the morphological and architectural parameters of the histology, and the expression of the glyceraldehyde-3-phosphate dehydrogenase (GAPDH) gene, by real-time polymerase chain reaction (PCR). The radiation-induced melanin pigmentation was standardized according to the doses of each radiation and evaluated by digital image analysis (Fontana-Masson). Results: The primary skin culture was standardized at room temperature using DMEM medium. The doses of UVB, UVA, and VL (blue light) that induced differential melanogenesis were: 166 mJ/cm2, 1.524 J/cm2, and 40 J/cm2. The expression of the GAPHD constitutional gene did not differ between the sample of skin processed immediately after tissue collection and the sample cultured for 72 h in the standardized protocol. Study limitations: This was a preliminary study that evaluated only the viability and integrity of the melanogenic system, and the effect of the radiation alone. Conclusions: The standardized model maintained viable melanocytic function for 72 h at room temperature, allowing the investigation of melanogenesis induced by different forms of radiation.

https://doi.org/10.1016/j.abd.2019.06.005 349 downloads

12.

Effects in the development of children exposed to zika virus in the fetal period: an integrative review
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Santos, Gerarlene Ponte Guimarães

; Gouveia, Márcia Teles de Oliveira

; Costa, Rayla Maria Pontes Guimarães

; Santos, Ana Maria Ribeiro dos

; Avelino, Fernanda Valéria Silva Dantas

Revista Brasileira de Enfermagem

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2020, Volume 73 elocation e20190883

Resumo: Pt En Es | Texto: Pt En Es | PDF: Pt | PDF: En | PDF: Es

RESUMO Objetivo: Conhecer as evidências disponíveis na literatura sobre os efeitos do vírus zika no desenvolvimento infantil pós-exposição no período fetal. Métodos: Trata-se de uma revisão integrativa da literatura com 16 artigos científicos encontrados em cinco bases de dados (PubMed, LILACS, CINAHL, Web of Science e Scopus), com base na pergunta norteadora: “Quais os efeitos no desenvolvimento de crianças de 0 a 6 anos de idade expostas ao vírus zika no período fetal?” Para a extração dos dados e avaliação dos estudos primários, utilizou-se a declaração STROBE. Resultados: A exposição ao vírus zika no período fetal resultou em diversas anomalias congênitas e/ou alterações no sistema nervoso central: microcefalia, problemas oculares, neurosensoriais, ventriculomegalia, calcificação intracraniana, cardiopatia, artrogripose, dentre outras. Conclusão: O vírus zika é neurotrópico; seu efeito no produto fetal causa danos irreparáveis à criança, portanto profissionais da saúde, em especial os enfermeiros, devem intensificar o cuidado materno-infantil.

ABSTRACT Objective: To know the evidence available in the literature on the effects of the zika virus in children development after fetal exposure. Methods: This is an integrative literature review with 16 scientific articles found in five databases (PubMed, LILACS, CINAHL, Web of Science and Scopus), based on the guiding question: “What are the effects in the development of children aged 0 to 6 years exposed to the zika virus in the fetal period? The STROBE statement was used for data extraction and evaluation of primary studies. Results: Exposure to the zika virus in the fetal period resulted in several congenital anomalies and/or changes in the central nervous system: microcephaly, ocular problems, neurosensorial problems, ventriculomegaly, intracranial calcification, cardiopathy, arthrogryposis, among others. Conclusion: The zika virus is neurotropic; its effect in the fetal nervous system causes irreparable damage to the child, so health professionals, especially nurses, must intensify maternal and also childcare.

RESUMEN Objetivo: Conocer las evidencias disponibles en la literatura sobre los efectos del virus zika en el desarrollo infantil postexposición en el período fetal. Método: Se trata de una revisión integrativa de la literatura con 16 artículos científicos encontrados en cinco bases de datos (PubMed, LILACS, CINAHL, Web of Science y Scopus), basada en la interrogación: “¿Cuáles los efectos en el desarrollo de niños de 0 a 6 años expuestos al virus zika en el período fetal?” Para extracción de datos y evaluación de estudios primarios, se utilizó la declaración STROBE. Resultados: La exposición al virus zika en el período fetal resultó en diversas anomalías congénitas y/o alteraciones en sistema nervioso central: microcefalia, problemas oculares, neurosensoriales, ventriculomegalia, calcificación intracraneal, cardiopatía, artrogriposis, etcétera. Conclusión: El virus zika es neurotrópico; su efecto en el producto fetal causa daños irreparables al niño, luego profesionales de salud, especialmente los enfermeros, deben intensificar el cuidado materno-infantil.

https://doi.org/10.1590/0034-7167-2019-0883 939 downloads

13.

Effects in the development of children exposed to zika virus in the fetal period: an integrative review
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Santos, Gerarlene Ponte Guimarães

; Gouveia, Márcia Teles de Oliveira

; Costa, Rayla Maria Pontes Guimarães

; Santos, Ana Maria Ribeiro dos

; Avelino, Fernanda Valéria Silva Dantas

Revista Brasileira de Enfermagem

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2020, Volume 73 Supl. 4 elocation e20190883

Resumo: En Es Pt | Texto: En Es Pt | PDF: En | PDF: Es | PDF: Pt

https://doi.org/10.1590/0034-7167-2019-0883 32 downloads

14.

Confirmed Invasive Pulmonary Aspergillosis and COVID-19: the value of postmortem findings to support antemortem management
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Santana, Monique Freire

; Pivoto, Guilherme

; Alexandre, Márcia A. Araujo

; Baía-da-Silva, Djane Clarys

; Borba, Mayla Gabriela da Silva

; Val, Fernando Almeida

; Brito-Sousa, Jose Diego

; Melo, Gisely Cardoso

; Monteiro, Wuelton Marcelo

; Souza, João Vicente Braga

; Pinheiro, Silviane Bezerra

; Ferreira, Luiz Carlos Lima

; Naveca, Felipe Gomes

; Nascimento, Valdinete Alves

; Corado, André Lima Guerra

; Hajjar, Ludhmila Abrahão

; Silva Neto, João Ricardo

; Siva, George Alan Villarouco

; Pasqualotto, Alessandro C.

; Lacerda, Marcus Vinícius Guimarães

Revista da Sociedade Brasileira de Medicina Tropical

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2020, Volume 53 elocation e20200401

Resumo: En | Texto: En | PDF: En

Abstract We present postmortem evidence of invasive pulmonary aspergillosis (IPA) in a patient with severe COVID-19. Autopsies of COVID-19 confirmed cases were performed. The patient died despite antimicrobials, mechanical ventilation, and vasopressor support. Histopathology and peripheral blood galactomannan antigen testing confirmed IPA. Aspergillus penicillioides infection was confirmed by nucleotide sequencing and BLAST analysis. Further reports are needed to assess the occurrence and frequency of IPA in SARS-CoV-2 infections, and how they interact clinically.

https://doi.org/10.1590/0037-8682-0401-2020 2017 downloads

15.

Risk assessment for perioperative pressure injuries
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Peixoto, Camila de Assunção

; Ferreira, Maria Beatriz Guimarães

; Felix, Márcia Marques dos Santos

; Pires, Patrícia da Silva

; Barichello, Elizabeth

; Barbosa, Maria Helena

Revista Latino-Americana de Enfermagem

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2019, Volume 27 elocation e3117

Resumo: En Es Pt | Texto: En Es Pt | PDF: En | PDF: Es | PDF: Pt

ABSTRACT Objectives: to evaluate and classify patients according to the Risk Assessment Scale for Perioperative Pressure Injuries; verify the association between sociodemographic and clinical variables and the risk score; and identify the occurrence of pressure injuries due to surgical positioning. Method: observational, longitudinal, prospective and quantitative study carried out in a teaching hospital with 278 patients submitted to elective surgeries. A sociodemographic and clinical characterization questionnaire and the Risk Assessment Scale for Perioperative Pressure Injuries were used. Descriptive, bivariate and logistic regression analyses were applied. Results: the majority of patients (56.5%) presented a high risk for perioperative pressure injury. Female sex, elderly group, and altered body mass index values were statistically significant (p < 0.05) for a higher risk of pressure injuries. In 77% of the patients, there were perioperative pressure injuries. Conclusion: most of the participants presented a high risk for development of perioperative decubitus ulcers. The female sex, elderly group, and altered body mass index were significant factors for increased risk. The Risk Assessment Scale for Perioperative Pressure Injuries allows the early identification of risk of injury, subsidizing the adoption of preventive strategies to ensure the quality of perioperative care.

RESUMEN Objetivos: evaluar y clasificar pacientes según la Escala de Evaluación de Riesgo para el Desarrollo de Lesiones Derivadas por Posicionamiento Quirúrgico, verificar si hay asociación entre variables sociodemográficas, clínicas y escore de riesgo e identificar si existen lesiones por presión, derivadas del posicionamiento quirúrgico. Método: estudio observacional, longitudinal, prospectivo y cuantitativo, realizado en hospital de enseñanza, con 278 pacientes sometidos a cirugías electivas. Se utilizó un cuestionario de caracterización sociodemográfica y clínica y Escala de Evaluación de Riesgo para el Desarrollo de Lesiones Derivadas por Posicionamiento Quirúrgico. Empleamos análisis descriptivos, bivariados y de regresión logística. Resultados: la mayoría de los pacientes (56,5%) presentó alto riesgo para lesión peri operatoria por posicionamiento. El sexo femenino, ancianos y valores de índice de masa corporal alterados fueron estadísticamente significativos (p <0,05) para mayor riesgo de existencia de esas lesiones. En el 77% de los pacientes hubo lesiones por posicionamiento. Conclusión: la mayoría de los participantes presentó alto riesgo de desarrollo de lesión peri operatoria por posicionamiento. El sexo femenino, ancianos e índice de masa corporal alterado fueron factores significativos para el aumento del riesgo. La Escala de Evaluación de Riesgo para el Desarrollo de Lesiones Derivadas del Posicionamiento Quirúrgico posibilita identificar precozmente el riesgo de lesión, subsidiando la adopción de estrategias preventivas para asegurar la calidad del periodo perioperatorio.

RESUMO Objetivos: avaliar e classificar pacientes segundo a Escala de Avaliação de Risco para Desenvolvimento de Lesões Decorrentes do Posicionamento Cirúrgico; verificar se há associação entre variáveis sociodemográficas, clínicas e escore de risco; e identificar a ocorrência de lesões por pressão, decorrentes do posicionamento cirúrgico. Método: estudo observacional, longitudinal, prospectivo e quantitativo, realizado em hospital de ensino, com 278 pacientes submetidos a cirurgias eletivas. Utilizaram-se questionário de caracterização sociodemográfica e clínica e Escala de Avaliação de Risco para Desenvolvimento de Lesões Decorrentes do Posicionamento Cirúrgico. Empregaram-se análises descritiva, bivariada e de regressão logística. Resultados: a maioria dos pacientes (56,5%) apresentou alto risco para lesão perioperatória por posicionamento. Sexo feminino, idoso e valores de índice de massa corporal alterados foram estatisticamente significativos (p<0,05) para maior risco de ocorrência dessas lesões. Em 77% dos pacientes houve lesões por posicionamento. Conclusão: a maioria dos participantes apresentou alto risco para desenvolvimento de lesão perioperatória por posicionamento. Sexo feminino, idoso e índice de massa corporal alterado foram fatores significativos para aumento do risco. A Escala de Avaliação de Risco para Desenvolvimento de Lesões Decorrentes do Posicionamento Cirúrgico possibilita identificar risco de lesão precocemente, subsidiando a adoção de estratégias preventivas para assegurar a qualidade do cuidado perioperatório.

https://doi.org/10.1590/1518-8345.2677-3117 6 downloads

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