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ABSTRACT Background: Critical illness is a major ongoing health care burden worldwide and is associated with high mortality rates. Sodium-glucose cotransporter-2 inhibitors have consistently shown benefits in cardiovascular and renal outcomes. The effects of sodium-glucose cotransporter-2 inhibitors in acute illness have not been properly investigated. Methods: DEFENDER is an investigator-initiated, multicenter, randomized, open-label trial designed to evaluate the efficacy and safety of dapagliflozin in 500 adult participants with acute organ dysfunction who are hospitalized in the intensive care unit. Eligible participants will be randomized 1:1 to receive dapagliflozin 10mg plus standard of care for up to 14 days or standard of care alone. The primary outcome is a hierarchical composite of hospital mortality, initiation of kidney replacement therapy, and intensive care unit length of stay, up to 28 days. Safety will be strictly monitored throughout the study. Conclusion: DEFENDER is the first study designed to investigate the use of a sodium-glucose cotransporter-2 inhibitor in general intensive care unit patients with acute organ dysfunction. It will provide relevant information on the use of drugs of this promising class in critically ill patients. ClinicalTrials.gov registry: NCT05558098

RESUMO Antecedentes: A doença crítica é um importante ônus permanente da assistência médica em todo o mundo e está associada a altas taxas de mortalidade. Os inibidores do cotransportador de sódio-glicose do tipo 2 têm demonstrado consistentemente benefícios nos desfechos cardiovasculares e renais. Os efeitos dos inibidores do cotransportador de sódio-glicose do tipo 2 em doenças agudas ainda não foram devidamente investigados. Métodos: O DEFENDER é um estudo de iniciativa do investigador, multicêntrico, randomizado, aberto, desenhado para avaliar a eficácia e a segurança da dapagliflozina em 500 participantes adultos com disfunção orgânica aguda hospitalizados na unidade de terapia intensiva. Os participantes aptos serão randomizados 1:1 para receber 10mg de dapagliflozina e o tratamento padrão por até 14 dias ou apenas o tratamento padrão. O desfecho primário é um composto hierárquico de mortalidade hospitalar, início de terapia renal substitutiva e tempo de internação na unidade de terapia intensiva, até 28 dias. O monitoramento da segurança será rigoroso durante todo o estudo. Conclusão: O DEFENDER é o primeiro estudo desenvolvido para investigar o uso de um inibidor do cotransportador de sódio-glicose do tipo 2 em pacientes de unidade de terapia intensiva geral com disfunção orgânica aguda. O estudo fornecerá informações relevantes sobre o uso de medicamentos dessa classe promissora em pacientes críticos. Registro ClincalTrials.gov: NCT05558098

https://doi.org/10.5935/2965-2774.20230129-en

Índices fisiológicos de siete especies forrajeras en diferentes ambientes tropicales
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Andrea-Hernández, Erika

; Duran-Castro, Carlos Vicente

; Silva-Aguilar, Bernardo

; Juárez-Lagunes, Francisco Indalecio

; Vélez-Terranova, Oscar Mauricio

; Mejía de Tafur, María Sara

Revista mexicana de ciencias agrícolas

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Ago 2023, Volume 14 Nº 4 Páginas 519 - 529

Resumo: Es En | Texto: Es En | PDF: Es | PDF: En

Resumen Constantemente los forrajes deben realizar procesos de adaptación a los diferentes cambios en los factores ambientales lo cual conlleva a que sus variables fisiológicas se vean afectadas. El objetivo fue evaluar el comportamiento fisiológico de siete especies forrajeras tropicales en diferentes condiciones ambientales durante 2019 en Palmira, Colombia. Se implementó un diseño de bloques completos al azar, en tres localidades con diferentes altitudes, con cuatro repeticiones por especie para un total de 28 unidades experimentales por localidad. Se utilizó un analizador de medición fotosintético portátil Lcpro+, para la toma de datos de la tasa de fotosíntesis (TA), conductancia estomática (G s ), tasa de transpiración (E) y CO2 Interno (Ci). Los datos recolectados fueron analizados mediante una comparación de medias con la prueba de Duncan (p≤ 0.05). Los indicadores fisiológicos de la especie Estrella, Kikuyo y la leguminosa Centrosema molle en las tres altitudes y las dos épocas demostrarían los mecanismos de adaptación que estas desarrollan en lugares adversos a los que se establecen.

Abstract Forages must constantly carry out processes of adaptation to different changes in environmental factors, which leads to their physiological variables being affected. The objective was to evaluate the physiological behavior of seven tropical forage species under different environmental conditions in 2019 in Palmira, Colombia. A randomized complete block design was implemented in three localities with different altitudes, with four repetitions per species for a total of 28 experimental units per locality. An Lcpro+ portable photosynthetic measurement analyzer was used to collect data on photosynthesis rate (TA), stomatal conductance (Gs), transpiration rate (E) and Internal CO2 (Ci). The collected data were analyzed by a comparison of means with Duncan’s test (p≤ 0.05). The physiological indicators of the species Star, Kikuyu and the legume Centrosema molle in the three altitudes and the two seasons would demonstrate the mechanisms of adaptation that they develop in adverse places in which they are established.

https://doi.org/10.29312/remexca.v14i4.3475

Validation of an Analytical Method by Headspace Gas Chromatography with Flame Ionization and Evaluation of Matrix Effect of Volatile Compounds in Cat Food
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Carvalho, Bruno M.

; Santos, Patrícia D. S. dos

; Silva, Geovane A. R. da

; Senes, Carlos E. R.

; Visentainer, Jesuí V.

; Santos, Oscar O.

Journal of the Brazilian Chemical Society

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Ago 2023, Volume 34 Nº 8 Páginas 1130 - 1138

Resumo: En | Texto: En | PDF: En

This study describes the validation of a headspace gas chromatography with flame ionization (HS-GC-FID) method for the determination of propanal, pentanal, hexanal, octanal, and trans-2-nonenal originated by lipid oxidation from cat food samples, as well as the evaluation of the matrix effect in the results. This method was applied to the analysis of commercial cat food and proved to be suitable for the determination of these volatile compounds in different samples. Mean recoveries between 88 and 109% were obtained and repeatability expressed as relative standard deviation was always lower than 6.95%. The intra- and inter-assay precisions ranged from 0.44 to 20.88% and from 0.45 to 20.52%, respectively. In addition, the matrix effect of cat food samples was determined by comparing the slopes of the standard addition method, and the external calibration curve and its influences were verified. These results highlight the high potential of this method, which allows the determination of lipid oxidation products in cat food samples directly, without requiring prior sample preparation techniques.

https://doi.org/10.21577/0103-5053.20230026

Guía de práctica clínica para el manejo del cáncer de pulmón de células pequeñas: enfermedad extensa
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Cabrera-Miranda, Luis A.

; Díaz-García, Diego A.

; Corona-Cruz, José F.

; Lozano-Ruiz, Francisco J.

; Sánchez-Reyes, Roberto

; Álvarez-Bojórquez, Mario E.

; Blake-Cerda, Mónika

; Rivera-Márquez, Raúl

; López-Saucedo, Raúl A.

; Pérez-Álvarez, Sandra I.

; Bolaño-Guerra, Laura M.

; Alatorre-Alexander, Jorge A.

; Alexander-Meza, Francisco

; Barrón-Barrón, Feliciano

; Blanco-Vázquez, Yazmín C.

; Campos-Gómez, Saúl

; Mata-Moya, Dolores de la

; Figueroa-Martínez, Pedro

; González-Cisneros, Paulina E.

; Íñiguez-García, Marco A.

; Lázaro-León, Jesús M.

; Loyola-García, Ulises

; Morales-Rivera, Marcelino

; Olivares-Torres, Carlos

; Ramos-Ramírez, Maritza

; Sáenz-Frías, Julia A.

; Silva-Bravo, Fernando

; Trejo-Rosales, Rogelio

; Souto-del Bosque, Miguel

; Arrieta, Óscar

Gaceta mexicana de oncología

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Jun 2023, Volume 22 Nº 2 Páginas 55 - 73

Resumo: Es En | Texto: Es En | PDF: Es | PDF: En

Resumen Antecedentes: El cáncer de células pequeñas (CPCP) representa el 13-15% del total de neoplasias primarias de pulmón. Se caracteriza por su rapidez en la tasa de crecimiento y en el desarrollo de metástasis a distancia. Objetivos: Orientar y estandarizar el tratamiento del CPCP enfermedad extensa en México basado en evidencia clínica nacional e internacional. Material y métodos: Este documento se desarrolló como una colaboración del Instituto Nacional de Cancerología y la Sociedad Mexicana de Oncología en cumplimiento con estándares internacionales. Se integró un grupo conformado por oncólogos médicos, cirujanos oncólogos, cirujanos de tórax, radio-oncólogos y metodólogos con experiencia en revisiones sistemáticas de la literatura y guías de práctica clínica. Resultados: Se consensaron, por el método Delphi y en reuniones a distancia, las recomendaciones en CPCP enfermedad extensa, producto de preguntas de trabajo. Se identificó y evaluó la evidencia científica que responde a cada una de dichas preguntas clínicas antes de incorporarla al cuerpo de la guía. Conclusión: Esta guía proporciona recomendaciones clínicas para el manejo de la enfermedad extensa del CPCP y durante el proceso de toma de decisiones de los clínicos involucrados con su manejo en nuestro país para mejorar la calidad de la atención clínica para estos pacientes.

Abstract Background: Small cell lung cancer (SCLC) represents 13-15% of all primary lung neoplasms and is characterized by its rapid growth rate and the rapid development of distant metastases. Objectives: To guide and standardize the treatment of extensive disease small cell lung cancer in Mexico based on national and international clinical evidence. Material and methods: This document was developed as a collaboration between the National Cancer Institute and the Mexican Society of Oncology in compliance with international standards. An interdisciplinary group was formed, including medical oncologists, oncological surgeons, thoracic surgeons, radiation oncologists, and methodologists with experience in systematic reviews of the literature and clinical practice guidelines. Results: A consensus was reached, both by the Delphi method and in remote meetings, of extensive disease recommendations resulting from work questions. The scientific evidence that answers each of these clinical questions was identified and critically evaluated, before being incorporated into the body of evidence of the Guide. Conclusions: This Clinical Practice Guide provides clinical recommendations for the management of extensive disease of SCLC to contribute to the decision-making process of the clinicians involved with its management in our country, hoping that this will contribute to improving the quality of clinical care in these patients.

https://doi.org/10.24875/j.gamo.22000122

Efecto de cinco métodos de cocción en las características fisicoquímicas, nutricionales y sensoriales de trucha arcoiris (Oncorhynchus mykiss)
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Ramos, Miriam

; Bustillos, Rolys

; Santolalla, Salomón

; Tuesta, Tarsila

; Silva-Paz, Reynaldo

; Jordán-Suárez, Oscar

Scientia Agropecuaria

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Abr 2023, Volume 14 Nº 2 Páginas 247 - 257

Resumo: En Es | Texto: En Es | PDF: En | PDF: Es

Abstract This study aimed to evaluate the effect of five cooking methods (steam, grill, oven, frying and microwave) on farm-raised rainbow trout's sensory acceptability, physicochemical characteristics, and nutritional value. A survey was conducted with 307 consumers to create a marinade made with salt, garlic, cumin and pepper. The fillets marinated in this mixture were cooked, and photographs were taken to determine their sensory profile using the Check All That Apply (CATA) method, as well as their appearance through both visual (n = 289) and virtual (n = 100) surveys. Similarity was found between the sensory attribute maps for frying, oven and grilling in both evaluation methods. Significant differences (p < 0.05) in proximal composition were observed between the cooking techniques studied because of their technological parameters. The methods with the best visual acceptability were frying and microwave, and they caused an increase in the peroxide index. The n-6/n-3 ratio for both techniques (3.62 and 2.05) was within the requirement, being higher in frying due to the predominance of Omega 6 fatty acids incorporated by the oil used. This study demonstrated that the Peruvian consumer prefers cooking techniques characterized by ease of preparation and marked the development of color and texture attributes.

Resumen El objetivo de este estudio fue evaluar el efecto de cinco métodos de cocción (vapor, plancha, horno, microondas, fritado) en las características fisicoquímicas, valor nutricional y aceptabilidad sensorial de trucha arcoiris (Oncorhynchus mykiss) de origen piscícola. Se aplicó una encuesta a 307 consumidores para definir la formulación de la solución de adobado constituida por sal, ajos, comino y pimienta. Los filetes marinados en esta solución fueron cocinados por cada método y se registraron fotografías para la determinación de los perfiles sensoriales mediante el método CATA (Check All That Apply), así como la aceptabilidad de la apariencia mediante la evaluación virtual (n = 289) y presencial (n = 100). En ambas modalidades se encontró una similitud entre los mapas de atributos sensoriales para el fritado, horneado y a la plancha. Se evidenciaron diferencias significativas (p < 0,05) en la composición proximal entre las técnicas estudiadas como consecuencia de los parámetros tecnológicos de cocción. El fritado y microondas obtuvieron la mayor aceptabilidad en apariencia y ocasionaron un incremento del índice de peróxido. La relación n-6/n-3 para ambas técnicas (3,62 y 2,05) se ubicó dentro del requerimiento, siendo mayor en la fritura debido al predominio de ácidos grasos Omega 6 incorporados por el aceite empleado. La elección de estos dos métodos demuestra que el consumidor peruano aprueba técnicas caracterizadas por la facilidad de preparación y un marcado desarrollo de atributos de color y textura.

https://doi.org/10.17268/sci.agropecu.2023.022

Guía de práctica clínica para el manejo del cáncer de pulmón de células pequeñas: enfermedad limitada
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Cabrera-Miranda, Luis A.

; Lozano-Ruiz, Francisco J.

; Blake-Cerda, Mónika

; Corona-Cruz, José F.

; Sánchez-Reyes, Roberto

; Pérez-Álvarez, Sandra I.

; Díaz-García, Diego A.

; Álvarez-Bojórquez, Mario E.

; Rivera-Márquez, Raúl

; López-Saucedo, Raúl A.

; Bolaño-Guerra, Laura M.

; Maldonado-Magos, Federico

; Aldaco-Sarvide, Fernando

; Alvarado-Zermeño, Adriana

; Barajas-Figueroa, Luis J.

; Bautista-Aragón, Yolanda

; Bolaños-Morales, Francina V.

; Castillo-Ortega, Graciano

; Félix-Leyva, Jesús A.

; Gerson-Cwilich, Raquel

; Guzmán-de Alba, Enrique

; López-Galindo, Ángel A.

; Mariscal-Ramírez, Carlos

; Piñeiro-Retif, Rafael

; Ramos-Prudencio, Rubí

; Rodríguez-Cid, Jerónimo

; Silva-Bravo, Fernando

; Arrieta, Óscar

Gaceta mexicana de oncología

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Mar 2023, Volume 22 Nº 1 Páginas 3 - 23

Resumo: Es En | Texto: Es En | PDF: Es | PDF: En

Resumen Antecedentes: El cáncer de células pequeñas (CPCP) representa el 13-15% del total de neoplasias primarias de pulmón. Se caracteriza por su rapidez en la tasa de crecimiento y en el desarrollo de metástasis a distancia. Objetivos: Orientar y estandarizar el tratamiento del CPCP, enfermedad limitada, en México, basado en evidencia clínica nacional e internacional. Material y métodos: Este documento se desarrolló como una colaboración entre el Instituto Nacional de Cancerología y la Sociedad Mexicana de Oncología en cumplimiento con estándares internacionales. Se integró un grupo conformado por oncólogos médicos, cirujanos oncólogos, cirujanos de tórax, radio-oncólogos y metodólogos con experiencia en revisiones sistemáticas de la literatura y guías de práctica clínica. Resultados: Se consensuaron, por el método Delphi y en reuniones a distancia, las recomendaciones en CPCP enfermedad limitada, producto de las preguntas de trabajo. Se identificó y evaluó críticamente la evidencia científica que responde a cada una de dichas preguntas clínicas, antes de incorporarla a la guía. Conclusión: Esta guía proporciona recomendaciones clínicas para el manejo de la enfermedad limitada del CPCP y durante el proceso de toma de decisiones de los clínicos involucrados con su manejo en nuestro país para mejorar la calidad de la atención clínica en estos pacientes.

Abstract Background: Small cell lung cancer (SCLC) represents 13-15% of all primary lung neoplasms and is characterized by rapid growth rate and development of distant metastases. Objectives: To guide and standardize the treatment of limited disease small cell lung cancer in Mexico based on national and international clinical evidence. Material and methods: This document was developed as a collaboration between the National Cancer Institute and the Mexican Society of Oncology in compliance with international standards. An interdisciplinary group was formed, including medical oncologists, oncological surgeons, thoracic surgeons, radiation oncologists, and methodologists with experience in systematic reviews of the literature and clinical practice guidelines. Results: Consensus recommendations were reached, both by the Delphi method and in remote meetings, for limited SCLC disease resulting from the same number of work questions. The scientific evidence that answers each of these clinical questions was identified and critically evaluated, before being incorporated into the body of evidence of the guide. Conclusion: This guide provides clinical recommendations for the management of limited disease SCLC to contribute to the decision-making process of the clinicians involved with its management in our country, hoping that this will contribute to improving the quality of clinical care in these patients.

https://doi.org/10.24875/j.gamo.22000121

Tratamiento homeopático de semillas de pepino contaminadas con herbicida auxínico
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Felito, Ricardo Adriano

; Yamashita, Oscar Mitsuo

; Gervazio, Wagner

; Carvalho, Marco Antonio Camillo de

; Silva, Ivone Vieira da

; Cândido, Aureane Cristina Teixeira Ferreira

Revista mexicana de ciencias agrícolas

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Mar 2023, Volume 14 Nº 2 Páginas 145 - 157

Resumo: Es En | Texto: Es En | PDF: Es | PDF: En

Resumen El objetivo del presente estudio fue investigar el uso de preparaciones homeopáticas para reducir los efectos nocivos causados por los residuos de herbicidas de auxina en la germinación de semillas y el desarrollo temprano de plántulas de pepino. El diseño estadístico fue completamente al azar (DIC) en un esquema factorial 3x5+2, con cuatro repeticiones. Los tratamientos fueron la combinación de tres preparados homeopáticos (Nux vomica, Carbo vegetabilis y Arsenicum album), en cinco dinamizaciones centesimales (6CH; 12CH; 18CH; 24CH y 30CH), más dos testigos (T0= agua destilada y TH= herbicida (Artys™) sin tratamiento homeopático). Cada unidad experimental consistió en cajas de acrílico transparente (Gerbox™) con 25 semillas de pepino, distribuidas en dos hojas de papel para germinación y humedecidas con tratamientos homeopáticos. Las unidades experimentales se mantuvieron en cámara de germinación DBO (ambiente controlado a 25 ºC y 12 h luz). Al décimo día después de la instalación del experimento se evaluaron las siguientes variables: porcentaje de germinación, longitud de brotes, longitud de raíces, fitointoxicación, porcentaje de plántulas muertas y masa seca total. El tratamiento homeopático de semillas de pepino contaminadas con herbicida picloram + 2,4-D (Artys™) provoca cambios positivos, provocando efectos interesantes en la germinación de las semillas, pero no es eficiente para la neutralización total del efecto causado por el herbicida picloram + 2,4-D y desarrollo de plántulas tempranas de pepino. Sin embargo, para algunas variables los resultados no son concluyentes con los preparados (Nux vomica, Carbo vegetabilis y Arsenicum album) y sus ultradiluciones (6CH, 12CH, 18CH, 24CH y 30CH), requiriendo más investigación para evaluar y describir la complejidad de propiedades inherente al tratamiento homeopático.

Abstract The aim of the present study was to investigate the use of homeopathic preparations to reduce the harmful effects caused by auxin herbicide residues on seed germination and early development of cucumber seedlings. The statistical design was completely randomized (DIC) in a 3x5+2 factorial scheme, with four replications. The treatments were the combination of three homeopathic preparations (Nux vomica, Carbo vegetabilis and Arsenicum album), in five centesimal dynamizations (6CH; 12CH; 18CH; 24CH and 30CH), plus two controls (T0= distilled water and TH = herbicide (Artys™) without homeopathic treatment). Each experimental unit consisted of transparent acrylic boxes (Gerbox™) with 25 cucumber seeds, distributed over two sheets of paper for germination and moistened with homeopathic treatments. The experimental units were kept in a BOD germination chamber (in a controlled environment at 25 ºC and 12 ho of light). On the tenth day after the installation of the experiment, the following variables were evaluated: percentage of germination, shoot length, root length, phytointoxication, percentage of dead seedlings and total dry mass. The homeopathic treatment of cucumber seeds contaminated with picloram + 2,4-D herbicide (Artys™) causes positive changes, causing interesting effects on seed germination, but it is not efficient for the total neutralization of the effect caused by the herbicide 2 picloram + 2,4-D and development of early cucumber seedlings. However, for some variables, the results are inconclusive with the preparations (Nux vomica, Carbo vegetabilis and Arsenicum album), and their ultradilutions (6CH, 12CH, 18CH, 24CH and 30CH), requiring more research to evaluate and describe the complexity of properties inherent to homeopathic treatment.

https://doi.org/10.29312/remexca.v14i2.3163

Informalidad y nanoempresas en localidades perimetropolitanas de la Ciudad de México
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Rodríguez Medina, Oscar

; Alvarado Lagunas, Elías

; Sánchez Silva, Mario

Problemas del desarrollo

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Mar 2023, Volume 54 Nº 212 Páginas 55 - 77

Resumo: Es En | Texto: Es En | PDF: Es | PDF: En

Resumen El objetivo del presente artículo es estudiar las variables que influyen en sobre la preferencia por la formalidad o informalidad de las nanoempresas en la localidad perimetropolitana de Milpa Alta, en la Ciudad de México. Para ello se realizó un experimento controlado a 122 individuos, en el que se destacaron las prerrogativas de la formalidad para obtener una matriz de transición y tres modelos Logit. Los resultados indican que 27% de los empresarios están dispuestos a transitar a la formalidad. Además, en la medida que el monto de la inversión inicial se incrementa, la preferencia por la informalidad disminuye, mientras que la preferencia por la formalidad incrementa cuando la escolaridad del individuo corresponde a licenciatura o ingeniería y, fite, entre más baja es la inversión inicial, resulta más difícil la transición informal-formal.

Abstract This article aims to study the variables that influence the preference for nano-businesses operating under a formal or informal status in the perimetropolitan area of Milpa Alta, Mexico City. For this purpose, a controlled experiment was carried out on 122 individuals, in which the advantages of a formal business status were highlighted in order to obtain a transition matrix and three Logit models. The results indicate that 27% of entrepreneurs are willing to transition to a formal business operation. Furthermore, as the initial investment increases, the preference for informality decreases, while the preference for formality increases when the individual has completed a bachelor's or engineering degree. Finally, the lower the initial investment, the more complex the informal-formal transition becomes.

https://doi.org/10.22201/iiec.20078951e.2023.212.69898

Influence of Breastfeeding Time on Caloric Composition and IL-10 and TNF-α Cytokines, Fatty Acids, and Triacylglycerol in Human Milk Colostrum in Previous, Intermediate, and Posterior Milk
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Castro, Matheus C

; Oliveira, Francieli S

; Alves, Eloize S

; Zacarias, Joana M. V

; Alencar, Josiane B

; Silva, Jiuliane M. da

; Visentainer, Jeane E. L

; Santos, Oscar O

; Visentainer, Jesui V

; Ichisato, Sueli M. T

Journal of the Brazilian Chemical Society

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Fev 2023, Volume 34 Nº 2 Páginas 201 - 212

Resumo: En | Texto: En | PDF: En

The composition of human milk (HM) includes changes under the influence of factors such as genetics, stage of lactation, time of day, and even breastfeeding time. However, the authors are not aware of studies that evaluated the influence of breastfeeding time on fatty acid composition and cytokine. Thus, the objective of this study was to evaluate the influence of breastfeeding time (previous, intermediate, posterior milk) on kilocalorie concentration, fatty acid (FA) composition, and concentration of the cytokines interleukin-10 (IL-10), interferon factors for necrotic tumor (TNF-α) in HM colostrum. The results showed that the concentration of kilocalories was higher in posterior milk than in the previous, the composition of the main fatty acids found in the samples was influenced by the breastfeeding time, and the concentration of IL-10 and TNF-α was influenced in all samples with exception to mother 2. The principal component analysis explained 71% of the variances in the results. Thus, we concluded that the breastfeeding time is a factor that influences the concentration of kilocalories, and if it is necessary to use a more caloric milk, it is recommended to use the posterior milk; the FAs composition and the evaluated cytokines were also influenced by the breastfeeding time.

https://doi.org/10.21577/0103-5053.20220099

10.

Una especie nueva de Diplocentrus Peters, 1861 (Scorpiones: Diplocentridae) del estado de Sonora, México
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Villa-Corella, Héctor Hugo

; Silva-Kurumiya, Hugo

; Barrales-Alcalá, Diego

; Van Devender, Thomas R.

; Francke, Oscar Federico

Acta zoológica mexicana

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2023, Volume 39 elocation e2277

Resumo: En Es | Texto: En Es | PDF: En | PDF: Es

Abstract A new species of scorpion, Diplocentrus leptomanus sp. nov., is described from northeastern Sonora, Mexico. This contribution increases the number of species in the genus Diplocentrus present in the state to five, two of which are endemic to the state. Morphological comparisons are provided with other species in the region, Diplocentrus williamsi Sissom & Wheeler, 1995, Diplocentrus peloncillensis Francke, 1975, and Diplocentrus spitzeri Stahnke, 1970.

Resumen Se describe una nueva especie de alacrán, Diplocentrus leptomanus sp. nov., proveniente de la región noreste del estado de Sonora, México. Con este aporte, se eleva a cinco el número de especies del género Diplocentrus presentes en el estado y a dos el número de especies endémicas en el área. Se provee una diagnosis comparativa con Diplocentrus williamsi Sissom & Wheeler, 1995, Diplocentrus peloncillensis Francke, 1975 y Diplocentrus spitzeri Stahnke, 1970, especies con las que guarda cercanía morfológica y geográfica.

https://doi.org/10.21829/azm.2023.3912277

11.

Bacterial cellulose biomaterials for the treatment of lower limb ulcers
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OLIVEIRA, GLÍCIA MARIA DE

; GOMES FILHO, ANTÔNIO OSCAR

; SILVA, JAIURTE GOMES MARTINS DA

; SILVA JUNIOR, ALBERTO GALDINO DA

; LINS, ESDRAS MARQUES

; OLIVEIRA, MARIA DANIELLY LIMA DE

; ANDRADE, CÉSAR AUGUSTO SOUZA DE

Revista do Colégio Brasileiro de Cirurgiões

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2023, Volume 50 elocation e20233536

Resumo: En Pt | Texto: En Pt | PDF: En | PDF: Pt

ABSTRACT Chronic ulcers of the lower limbs are common and recurrent, especially in the elderly population, they are disabling injuries that generate a great socioeconomic burden. This scenario encourages the development of new, low-cost therapeutic alternatives. The present study aims to describe the use of bacterial cellulose in the treatment of lower limb ulcers. This is an integrative literature review, carried out in the PubMed and Science Direct databases by associating the descriptors, with the inclusion criteria being clinical studies in the last 5 years, available in full in English, Portuguese and Spanish. Five clinical trials were analyzed and the main therapeutic effects obtained in the experimental groups that used bacterial cellulose dressings were a reduction in the area of the wounds, one of the studies showed a reduction of 44.18cm2 in the area of the wound, the initial lesions measured on average 89.46cm2 and at the end of the follow-up, they had an average of 45.28cm2, since the reduction in pain and the decrease in the number of exchanges were advantages described in all groups that used the BS. It is concluded that BC dressings are an alternative for the treatment of lower limb ulcers, their use also reduces operational costs related to the treatment of ulcers.

RESUMO As úlceras crônicas de membros inferiores são comuns e recorrentes principalmente na população idosa, são lesões incapacitantes e que geram grande ônus socioeconômico. Tal cenário incentiva o desenvolvimento de novas alternativas terapêuticas e de baixo custo. O presente estudo tem como objetivo descrever o uso da celulose bacteriana no tratamento de úlceras de membros inferiores. Trata-se de uma revisão integrativa da literatura, realizada nas bases de dados PubMed e Science Direct por meio da associação dos descritores, tendo como critério de inclusão estudos clínicos nos últimos 5 anos, disponíveis na integra em inglês, português e espanhol. Cinco ensaios clínicos foram analisados e os principais efeitos terapêuticos obtidos nos grupos experimentais que utilizaram os curativos de celulose bacteriana foram redução da área das feridas, um dos estudos apontou uma redução de 44,18cm2 da área da ferida, as lesões iniciais mediam em média 89,46cm2 e ao término do acompanhamento apresentaram uma média de 45,28cm2, já a redução da dor e diminuição do número de trocas foram vantagens descritas em todos os grupos que utilizaram a CB. Conclui-se que os curativos de CB são uma alternativa para o tratamento das úlceras de MMII, sua utilização reduz também os custos operacionais relacionados ao tratamento de úlceras.

https://doi.org/10.1590/0100-6991e-20233536-en

12.

Investigação da atividade eletroquímica de liga Al-Cu-Li após processo de soldagem por fricção e mistura
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Silva, Rejane Maria P. da

; Milagre, Mariana X.

; Araujo, João Victor de S.

; Ramirez, Oscar Mauricio P.

; Machado, Caruline de Souza C.

; Antunes, Renato A.

; Costa, Isolda

Química Nova

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2023, Volume 46 Nº 4 Páginas 307 - 318

Resumo: Pt | Texto: Pt | PDF: Pt

In this work, the local electrochemical activity of the zones coupled by Friction Stir Welding (FSW) of an Al-Cu-Li alloy was studied and the results were correlated to the microstructural characteristics of each zone. Electrochemical studies were carried out in the zones affected by welding using cyclic voltammetry (CV) and scanning electrochemical techniques (namely, SECM - Scanning Electrochemical Microscopy and LEIS - Local electrochemical impedance spectroscopy). The results showed that the welding joint (WJ) is predominantly cathodic relatively to the heat affected zones (HAZ). The HAZ was always anodic and showed the highest electrochemical activities among the tested ones. The high electrochemical activity of the HAZ was associated with the effect of galvanic coupling between the cathodic region (WJ) and the anodic region (HAZ). In addition, the advancing side (AS) presented increased electrochemical activity compared to the retreating one (RS).

https://doi.org/10.21577/0100-4042.20230014

13.

Do doses of controlled-release fertilizer and container volume influence the quality of Hymenaea courbaril seedlings?
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Smiderle, Oscar José

; Souza, Aline das Graças

; Maia, Sonicley da Silva

Revista Brasileira de Fruticultura

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2023, Volume 45 elocation e-249

Resumo: En Pt | Texto: En Pt | PDF: En | PDF: Pt

Abstract The objective was to determine the effects of doses of controlled-release fertilizer and container volume on the initial growth and quality of Hymenaea courbaril seedlings. The experimental design was completely randomized in a 2 x 4 factorial scheme, corresponding to two container volumes (1.8 and 2.2 L) and four doses of controlled-release fertilizer (0, 1.5, 3.0 and 4.5 g L-1 substrate) with eight replicates, each consisting of five seedlings (one in each container). The variables evaluated were: shoot height (H), stem diameter (SD), shoot dry mass (SDM, g plant-1), root dry mass (RDM, g plant-1), total dry mass (TDM, g plant-1), Dickson quality index (DQI), root volume (RV), nitrogen balance index (NBI) and chlorophylls. Controlled-release fertilizer at doses of 1.5 and 3.0 g L-1 provide Hymenaea courbaril seedlings with quality and sturdiness in both container sizes. Controlled-release fertilizer at the dose of 4.5 g L-1 is not indicated to obtain high quality standard in seedlings of Hymenaea courbaril, regardless of container volume.

Resumo O objetivo foi determinar os efeitos de doses de fertilizante de liberação controlada e o volume do recipiente no crescimento inicial e na qualidade de mudas de Hymenaea courbaril. O delineamento experimental foi inteiramente casualizado, em esquema fatorial 2 x 4, correspondendo a dois volumes de recipientes (1,8 e 2,2 L) e quatro doses de adubo de liberação controlada (0; 1,5; 3,0 e 4,5 g L-1 de substrato), com oito repetições, cada uma composta por cinco mudas (uma em cada recipiente). As variáveis avaliadas foram: altura da parte aérea (H), diâmetro do caule (DC), massa seca da parte aérea (MSPA, g planta-1), massa seca da raiz (MSR, g planta-1), massa seca total (MST, g planta-1), índice de qualidade de Dickson (IQD), volume radicular (VR), índice de balanço de nitrogênio (IBN) e clorofilas. O fertilizante de liberação controlada, nas doses de 1,5 e 3,0 g L-1, proporciona qualidade e robustez às mudas de Hymenaea Courbaril, em ambos os tamanhos de recipiente. O fertilizante de liberação controlada, na dose de 4,5 g L-1, não é indicado para obtenção dealto padrão de qualidade em mudas de Hymenaea courbaril, independentementedo volume do recipiente.

https://doi.org/10.1590/0100-29452023249

14.

Fracture Toughness of Vacuum Sintered AISI M3:2 High Speed Steels
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Silva Junior, Moisés Euclides da

; Silva, Wanderson Santana da

; Neves, Mauricio David Martins das

; Goldenstein, Hélio

; Araujo Filho, Oscar Olimpio de

Materials Research

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2023, Volume 26 elocation e20230179

Resumo: En | Texto: En | PDF: En

The aim of this investigation was to study and evaluate the fracture toughness (KICV) of an AISI M3:2 high speed steel that was prepared by powder metallurgical processing, which consisted of uniaxial cold compaction of irregularly shaped water atomized powders, without and with 0.3% of carbon in the form of graphite, followed by vacuum sintering to obtain compacts with densities close to its theoretical value. The sintered steels were then hardened by austenitizing, quenching and triple tempering. Chevron fracture toughness test samples were prepared from the compacts and the tests conducted to determine KICV. The microstructures of the specimens were examined by scanning electron microscopy (SEM), and the composition of the phases determined by x-ray diffraction analysis (XRD). The sizes of the primary carbides and of the austenite grains were determined using Quantikov digital analysis software. No significant difference in fracture toughness (KICV) between the two high speed steels AISI M3:2, austenitized at the different temperatures, was observed.

https://doi.org/10.1590/1980-5373-mr-2023-0179

15.

Adaptation of tetrazolium test methodology to estimate the viability of Eugenia stipitata McVaugh ssp. sororia McVaugh seeds
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Maia, Sonicley da Silva

; Smiderle, Oscar José

; Souza, Aline das Graças

; Torres, Salvador Barros

Hoehnea

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2023, Volume 50 elocation e142023

Resumo: En Pt | Texto: En Pt | PDF: En | PDF: Pt

ABSTRACT The tetrazolium test is a fast and effective method to determine seed viability. In this context, the objective was to adapt the methodology of the tetrazolium test, in relation to preconditioning, to determine the viability (Eugenia stipitata McVaugh ssp. sororia McVaugh) under different times of immersion in solution and seed size. The seeds of E. stipitata ssp. sororia need to go through preconditioning, fractionation being an indispensable technique to be performed before immersion of the seed in the tetrazolium solution, as it allows the contact of the salt with the tissue to be analyzed, which, when feasible, staining occurs (formation of the substance triphenyl-formazan). The immersion time of 26 hours in the tetrazolium solution (1% at 26 °C) is indicated for determining the viability of E. stipitata ssp. sororia seeds, regardless of the seed mass classes used.

RESUMO O teste de tetrazólio é um método rápido e eficaz para obter a viabilidade de sementes. Neste contexto, objetivou-se adequar a metodologia do teste de tetrazólio, em relação ao pré-condicionamento, para determinar a viabilidade de sementes de araçá-boi (Eugenia stipitata McVaugh ssp. sororia McVaugh) sob diferente tempo de imersão em solução e tamanho de semente. As sementes de E. stipitata ssp. sororia necessitam-se passar pelo pré-condicionamento, sendo o fracionamento uma técnica indispensável de ser realizada antes da imersão da semente na solução de tetrazólio, pois permite o contato do sal com o tecido a ser analisado, que quando viável ocorre a coloração (formação da substância trifenil-formazan). O tempo de imersão de 26 horas na solução de tetrazólio (1% a 26 °C) é indicado na determinação da viabilidade de sementes de Eugenia stipitata ssp. sororia. independentemente da classe de semente utilizada.

https://doi.org/10.1590/2236-8906e142023

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