ABSTRACT Objective: To assess the efficacy and safety of the use of midazolam as monotherapy, compared to the associated use of midazolam and hydroxyzine for minimum and moderate sedation of children in dental offices, using data obtained from clinical trials. Material and Methods: A systematic review protocol was developed and registered on PROSPERO (CR42020208633). An electronic search was carried out in Pubmed, Lilacs, Science Direct, Open Gray, Web of Science, and central Cochrane Library. No language restrictions were included. Clinical trials were carried out with children aged 0-12 years, using midazolam as monotherapy compared to the use of midazolam associated with hydroxyzine to verify the effectiveness and safety of oral sedation. The quality of the studies was individually assessed and grouped using the RoB 2 (Revised Cochrane risk-of-bias tool for randomized trials) and GRADE (Grading of Recommendations Assessment, Development and Evaluation) systems, respectively. Results: A total of 749 studies were found. After analyzing the inclusion and removal of duplicates, two studies were analyzed for the quality of evidence. Through this analysis, it was possible to verify the very low level of scientific evidence on the superiority of the efficacy and safety of the combined use of midazolam and hydroxyzine for oral sedation in children in dental offices. Conclusion: The conflicting results and limitations of the studies enabled to establish that there is insufficient evidence to support the use of these drugs combined. There is only evidence for the use of midazolam as monotherapy.

ABSTRACT This paper discusses the potential risk that COVID-19 generates for the development of enamel defects. This hypothesis was built based on the etiopathogenesis of enamel defects and the relationship with the symptom's characteristic of COVID-19. Pregnancy is a critical period for the child's development; exposure to pathological agents can cause systemic imbalances and risks of adverse perinatal and prenatal outcomes. The main clinical symptoms of this disease and its association with that dental outcome were considered. Fever, breathing, cardiovascular disorders, and diarrhea were related as potential etiological factors of ameloblast metabolism imbalance, which can interfere qualitatively and quantitatively in the development, maturation and mineralization of the tooth enamel. Molecular disorders derived from COVID-19, as well as their clinical symptoms, can be considered potential risk factors for the development of enamel defects. Individuals with enamel defects experienced high stress levels during pregnancy or early childhood. The approach adopted may help build new research to ensure understanding of the etiology of the development of dental enamel defects and its relationship with COVID-19. However, longitudinal studies need to be conducted to confirm the association between COVID-19 and adverse events during pregnancy.

Resumo Introdução O estudo da qualidade de vida de crianças portadoras de doenças crônicas, como o HIV, é essencial, visando um cuidado integral e holístico para os portadores da doença. Objetivo Avaliar a qualidade de vida e os fatores sociodemográficos associados de crianças portadoras do HIV. Método Estudo descritivo transversal, amostra de 78 crianças de ambos os sexos, faixa etária de 3 a 13 anos, atendidas em serviço de referência da cidade do Recife-PE. Foram utilizados o questionário Critério de Classificação Econômica Brasil, para caracterização socioeconômica, e a Escala de Qualidade de Vida da Criança (AUQEI). Para avaliar associação entre as variáveis, foram utilizados o teste Qui-quadrado de Pearson e o teste Exato de Fischer. A margem de erro utilizada foi de 5%. Resultados No tocante à qualidade de vida, ficar doente, brincar sozinho e a presença de bullying na escola apresentaram baixos índices de satisfação. Já itens como férias, aniversário, estar à mesa com a família e assistir televisão apresentaram altos níveis de satisfação. Conclusão As crianças desta pesquisa demonstraram uma qualidade de vida influenciada pelos aspectos negativos presentes em suas vidas. Desta forma, é necessária uma equipe multidisciplinar para o tratamento e prevenção de comorbidades, inclusive as psicossociais.

Abstract Background Studying the quality of life of children with chronic diseases, such as HIV, is essential, aiming at comprehensive and holistic care for people with the disease. Objective To assess the quality of life and sociodemographic associated factors in children with HIV. Method A descriptive cross-sectional study, with a sample of 78 children of both genders, aged between 3 and 13 years old, attending a reference service in the city of Recife-PE. Two questionnaires were used to collect data, the Brazilian Economic Classification Criteria questionnaire, to accomplish the socioeconomic characteristics, and the Quality of Life Scale for Children (AUQEI). Pearson's Chi-square test and Fisher's exact test evaluated the association between the variables. The margin of error was 5%. Results The quality of life, being sick, playing alone and the presence of bullying in school had low satisfaction rates. On the other hand, items such as vacations, birthday, being at the table with the family, and watching television showed high levels of satisfaction. Conclusions The children in this research demonstrated a quality of life influenced by the negative aspects present in their lives. Thus, a multidisciplinary team is needed for the treatment and prevention of comorbidities, including psychosocial ones.

Abstract Objective: To develop an educational mobile application as a dynamic platform provided free of charge, including several clinical and laboratory protocols for a wider range of skills and greater knowledge on the strategic axes of child dental care: Pediatric Dentistry and Orthodontics. Material and Methods: The prototype tool was structured as follows: development of clinical and laboratory contents to be addressed, software selection, layout format, inclusion of features, applicability and acceptability tests of the operational system, and indexation on the Play Store® application store (free of charge). Results: The mobile application has shown to be a tool capable of storing and providing data through various audiovisual media formats on clinical and laboratory contents of child dental care. Media resources were developed for the following themes: restorative dentistry in pediatric dentistry, radiographic techniques with pediatric patients, pulp therapy in deciduous teeth, traumatic injuries in the primary dentition, and preventive and interceptive orthodontics. The short-duration multimedia content, with different audiovisual formats, proved to be coherent with the peculiarities of each procedure, enabling to better visualize and understand the techniques. Moreover, the rewind, fast forward, and pause features were included in the mobile application, as well as the possibility of saving print screens, as well as highlighting and searching for contents of interest. Conclusion: The OdontoPed-Helpbox® demonstrated to be able to reach new strategies for the dynamic teaching-learning process, through operational efficiency. It proved to be a useful and instant tool for providing information to support clinical decision making in Dentistry.

Abstract Objective: To evaluate sleep quality and excessive daytime sleepiness in undergraduate dentistry students. Material and Methods: This research is characterized as an observational study of transversal type, having analysed undergraduate students in dentistry from a public university in the State of Pernambuco, Brazil. The sample consisted of 325 students enrolled between the 1st and 10th academic semester. Sleep quality was evaluated using the Pittsburgh Sleep Quality Index (PSQI), while excessive daytime sleepiness was analysed through the Epworth Sleepiness Scale (ESS). The t-Student and Mann-Whitney tests were used for the numerical values, with the F-test (ANOVA) or the Kruskal-Wallis test being used to compare more than two categories. Results: It was observed that 71.1% of students presented a poor sleep quality, with more than half of the students exhibiting excessive daytime sleepiness (58.1%). A relationship between sleep quality and the academic semester was verified. However, gender and age were not associated with sleep quality or with excessive daytime sleepiness. Conclusion: A high prevalence of poor sleep quality and excessive daytime sleepiness was observed among undergraduate students in dentistry. The data suggest that the undergraduate degree in Dentistry can influence the students’ quality of sleep, regardless of age or gender.

Este trabalho relata uma ocorrência de Meloidogyne enterolobii (sin. M. mayaguensis) no Estado do Mato Grosso do Sul, parasitando goiabeira (Psidium guajava), cv. Novo Milênio. O nematoide foi caracterizado e identificado pelo fenótipo da isoenzima esterase (Est) (Est M2, Rm: 0,7 e 0,9).

This paper reports an occurrence of Meloidogyne enterolobii (syn. M. mayaguensis) in the State of Mato Grosso do Sul, on guava (Psidium guajava), cv. Novo Milênio. The nematode was characterized and identified using esterase (Est) isozyme phenotype (Est M2, Rm: 0.7 e 0.9).