Resumo: A crítica produzida pelo pensamento feminista teve relevante contribuição para os estudos sociais ao enfatizar como a categoria gênero pode auxiliar na compreensão do mundo social. Mais recentemente, a abordagem interseccional do feminismo tem demostrado como gênero, articulado a outras categorias, como raça, classe, sexualidade, geração e localidade, pode auxiliar em análises mais complexas dos fenômenos sociais. Neste artigo, nosso objetivo é mobilizar a abordagem interseccional para revisar as noções de agência e de capacidades, visando oferecer um aporte sociológico analítico da constituição de sujeitos autônomos. Para isso, destacamos contribuições da abordagem interseccional e, em seguida, reelaboramos as noções de agência e de capacidades, tecendo combinações entre os fundadores e as fundadoras desses conceitos com representantes da abordagem interseccional.

Abstract: The critique produced by feminist thought had relevant contributions to social studies by emphasizing how the gender category can assist in understanding the social world. More recently, the intersectional approach to feminism has demonstrated how gender, linked to other categories such as race, class, sexuality, generation, and locality, can assist in more complex analyses of social phenomena. In this article our goal is to mobilize the intersectional approach to review the notions of agency and capabilities, aiming to offer an analytical sociological contribution on the constitution of autonomous subjects. To do so, we highlight contributions from the intersectional approach and then rework the notions of agency and capabilities, weaving combinations between the founders of these concepts with representatives of the intersectional approach.

Resumen: La crítica elaborada a partir del pensamiento feminista contribuyó de manera relevante a los estudios sociales al enfatizar cómo la categoría de género puede ayudar a comprender el mundo social. Más recientemente, el enfoque interseccional del feminismo ha demostrado cómo el género, vinculado a otras categorías como raza, clase, sexualidad, generación y localidad, puede ayudar a la hora de efectuar análisis más complejos de los fenómenos sociales. En este artículo nuestro objetivo es movilizar el enfoque interseccional para revisar las nociones de agencia y capacidades, con el objetivo de ofrecer un apo rte sociológico analítico sobre la constitución de sujetos autónomos. Para ello, destacamos las contribuciones del enfoque interseccional y luego reelaboramos las nociones de agencia y capacidades, tejiendo combinaciones entre los elementos fundadores de estos conceptos con representantes del enfoque interseccional.

Resumo O programa arquitetônico inclui fase de levantamento de dados que auxiliam na proposição do projeto. Diversos métodos para a coleta e análise desses dados são associados à avaliação pós-ocupação (APO), com observações e medições do projetista/pesquisador e percepções dos usuários sobre ambientes. A APO em escolas busca compreender esses espaços, que impactam no desenvolvimento das atividades de ensino/aprendizagem. O conceito de parâmetros de projeto (PPs) do século XXI deve ser considerado. Este estudo, exploratório, avaliou a aplicação de dois métodos visuais na APO, em escolas do Reino Unido, para retroalimentação de projetos, incluindo PPs como critério de avaliação. O diamond ranking, para análise de imagens, e análise de plantas, para indicação de observações, por meio de adesivos, pelos usuários. O resultado principal é a comprovação da eficácia de métodos visuais no desenvolvimento do programa e APO, fornecendo informações mais completas e ativando maior interesse na participação dos usuários. A seleção de imagens e a aplicação das ferramentas, validadas pela análise e compreensão de respostas, tiveram como base os PPs. Nas discussões de critérios e requisitos para a arquitetura escolar do século XXI, o desenvolvimento de métodos visuais para APO de escolas é visto como uma contribuição importante metodológica e conceitual.

Abstract The architectural programme process includes a data-gathering phase that assists in the development of design propositions. Numerous methods exist for the collection and analysis of this data, related to Post-Occupancy Evaluation (POE), with observations and measurements by the designer/researcher and perceptions by users about places. POE in schools seeks to understand these environments, which impact the quality of teaching/learning activities. Educational dynamics demand the consideration of the concept of 21st-century design patterns (DPs). This exploratory study evaluated two visual methods in POE, in schools of the UK, for design feedback, which include DPs as evaluation criteria. The methods evaluated were: diamond ranking, for image analysis, and floor plans analysis, with observations indicated by users, with stickers. The results showed these visual methods to be effective for briefing and POE. The methods provide better information, and users demonstrate greater interest in participating. The selection of images and the application of the visual tools are based on DPs, validated by the analysis and response comprehension. The development of visual methods for school POEs, with DPs insertion, is a methodological and conceptual contribution that discusses essential characteristics for 21st-century school architecture.

RESUMO No Brasil há poucas pesquisas sobre espaços museológicos que contribuem efetivamente para a gestão destes espaços e muito menos pesquisas com base em levantamentos in situ que priorizam o ponto de vista dos usuários dos museus, sejam estes visitantes, sejam funcionários, como importante estratégia para a conservação, a manutenção e a operação do edifício, do acervo e dos ambientes externos, mitigando, dessa forma, os riscos envolvidos. O artigo parte desse pressuposto e descreve como a Avaliação Pós-Ocupação (APO), um conjunto de métodos e técnicas que abrange a aferição da satisfação dos usuários e a verificação do desempenho físico dos ambientes, pode contribuir na formulação de diagnósticos e de recomendações com vistas à manutenção e à conservação consistentes para o caso de ambientes internos e externos antigos e que abrigam acervos. Para tanto, adotou-se como objeto de estudo exploratório o Museu Histórico e Cultural de Jundiaí - o Solar do Barão - para demonstrar a aplicabilidade da APO no caso de edifícios e espaços exteriores patrimoniados e colocar em discussão seus procedimentos metodológicos como alternativa de planejamento estratégico para museus, relacionando a conservação do edifício, do acervo e dos ambientes externos, com o acolhimento e a sensação de pertencimento dos usuários. Ao final e como resultados da APO aplicada em 2018 nesse caso em particular, apresenta-se um conjunto de recomendações técnico-espaciais e construtivas, para o conjunto edificado e ajardinado em questão e faz-se uma reflexão crítica sobre a necessidade de incorporar procedimentos de manutenção e de uso de espaços museológicos em suas rotinas operacionais e também utilizar esses resultados, sistematicamente organizados, para realimentar futuras readequações do próprio estudo de caso e, de forma ampliada, diretrizes para projetos arquitetônicos. Nessa perspectiva, o artigo destaca a importância do arquiteto especialista nas equipes que desenvolvem os projetos destinados ao restauro e à modernização desses espaços, bem como naquelas equipes que realizam a sua gestão, no decorrer do uso.

ABSTRACT In Brazil, there are few researches about museums that contribute more effectively to the management of these facilities and much less researches based on in situ surveys that priorize museum users, whether visitors or staff as an important conservation and maintenance strategy of the building, the collection and the outdoor environments, thus mitigating the risks involved. The article starts from this assumption and describes how Post-Occupancy Evaluation (POE), a set of methods and techniques that encompasses the measurement of user perception and satisfaction and the verification of the physical performance of environments can contribute to address diagnoses and recommendations for consistent maintenance and upkeep for older indoor and outdoor collections (including the building itself). To this end, the Jundiaí Historical and Cultural Museum - Solar do Barão - sited at the State of São Paulo, Brazil, was adopted as an exploratory study object to demonstrate the applicability of POE in the case of heritage buildings and their outdoor spaces and to discuss its methodological procedures as an alternative to strategic planning for museums, relating the conservation of the building, the collection and the external environments, with the welcome and the sense of belonging of the visitors and staff. To sum up and as a result of the POE applied in 2018 in this particular case, we present a set of technical-spatial and constructive recommendations based on research, for the built and landscaped set in question and a critical reflection on the need for incorporate procedures for the maintenance, use and operation of museum on daily basis and also use these results, systematically organized, to feedback future readjustments of the case study itself and, broadly, guidelines for architectural designs. In this perspective, the article highlights the importance of the expert architect in the teams that develop the designs for the restoration and modernization of these environments, as well as in those teams that manage them during their use.

ABSTRACT We aimed to study the potential use of carcass condemnation data of broiler chicken slaughterhouses in Brazil as indicators in an animal welfare monitoring program, and to identify points to be addressed to increase data reliability. Data from 2010 to 2015 in the states of Paraná (PR), Santa Catarina (SC) and Rio Grande do Sul (RS) were used. Fractures and bruising were recorded together, representing the most prevalent welfare problem, followed by skin lesion or inflammation. In PR, progressive increases on injury, arthritis, ineffective bleeding, and air sacculitis condemnation may reveal important welfare aspects. High correlation between AWI within PR was more commonly observed than in RS and SC, perhaps as a result of earlier implementation of local meat inspection standardization. Principal component analysis showed changes on condemnation data pattern in PR after standardization, pointing injury and Escherichia coli problems as the main causes for condemnation related to animal welfare. There is considerable potential to improve animal health and welfare surveillance using meat inspection structure that is already in place for food safety purposes, provided that the competent authority harmonizes the procedure of meat inspection among the States, sets specific animal welfare outcomes to be monitored, and integrates condemnation, transport and flock data. It seems crucial to update data collection to establish a routine that allows risk analysis regarding both food safety and animal welfare. In this regard, cooperative work between Federal Inspection and companies seems an interesting approach to promote transparency of the production processes, which would benefit society and animals.

Abstract Scientific literature on broiler chicken welfare in Brazilian industrial systems is scarce. This study aimed at assessing broiler chicken welfare on industrial farms in the State of Rio Grande do Sul, Southern Brazil, using the Welfare Quality(r) assessment protocol for poultry, to provide directly applicable scientific information. Results are presented as criteria scores ranging from 0 to 100, with higher scores indicating better welfare; and percentages of prevalence. The scores classified as excellent (above 80) were absence of prolonged thirst, absence of prolonged hunger, litter quality, breast blister and touch test. Enhanced scores (between 55 and 80) were comfort around resting, plumage cleanliness and dust sheet test. Acceptable scores (between 20 and 55) were thermal comfort, stocking density, absence of injuries, footpad dermatitis and hock burn; and unacceptable scores (below 20) were lameness and qualitative behavioral assessment. The median percentage of mortality and culled birds were 5.2% and 0.6%, respectively. This study provides useful information to select priorities of action on assessed farms and may contribute for setting up legal standards and guiding decisions related to animal welfare issues in Brazil.

Fundamentos:Evidências sugerem que a paroxonase 1 (PON1) confere importantes propriedades antioxidantes e antiinflamatórias quando associada à lipoproteína de alta densidade (HDL).Objetivo:Investigar as relações entre o SNP p.Q192R da PON1, parâmetros bioquímicos e aterosclerose carotídea em uma amostra populacional brasileira assintomática e normolipidêmica.Métodos:Foram estudados 584 voluntários (mulheres, n = 326; homens, n = 258; idade entre 19-75 anos). Foi extraído DNA genômico total e o SNP foi detectado na plataforma de genotipagem TaqMan® SNP OpenArray®(Applied Biosystems, Foster City, CA). Foram dosadas lipoproteínas e apolipoproteínas plasmáticas, e a atividade da PON1 foi medida utilizando-se paraoxon como substrato. Foi utilizada ultrassonografia bidimensional de alta resolução para determinar a espessura íntimo‑medial das artérias carótidas (EIMc) e a presença de placas ateroscleróticas carotídeas em um subgrupo de indivíduos (n = 317).Resultados:A presença de p.192Q esteve associada a um aumento significativo da atividade da PON1 (RR = 12,30 (11,38); RQ = 46,96 (22,35); QQ = 85,35 (24.83) μmol/min; p < 0,0001), HDL-C (RR = 45 (37); RQ = 62 (39); QQ= 69 (29) mg/dL; p < 0,001) e apo A-1 (RR = 140,76 ± 36,39; RQ = 147,62 ± 36,92; QQ = 147,49 ± 36,65 mg/dL; p = 0,019). A análise de regressãostepwise mostrou que heterozigotos e portadores de p.192Q influenciaram 58% da atividade da PON1 em relação ao paraoxon. A análise de regressão linear univariada demonstrou que não houve associação entre o SNP p.Q192R e a EIMc média; como resultado, na análise de regressão múltipla nenhuma variável foi selecionada com 5% de significância. Os parâmetros estudados não se associaram à presença de placas carotídeas na análise de regressão logística.Conclusão:Em indivíduos de baixo risco, a presença da variante p.192Q daPON1 mostrou-se associada a um perfil lipídico plasmático benéfico e à ausência de aterosclerose de carótida.

Background:Evidences suggest that paraoxonase 1 (PON1) confers important antioxidant and anti-inflammatory properties when associated with high-density lipoprotein (HDL).Objective:To investigate the relationships between p.Q192R SNP ofPON1, biochemical parameters and carotid atherosclerosis in an asymptomatic, normolipidemic Brazilian population sample.Methods:We studied 584 volunteers (females n = 326, males n = 258; 19-75 years of age). Total genomic DNA was extracted and SNP was detected in the TaqMan® SNP OpenArray® genotyping platform (Applied Biosystems, Foster City, CA). Plasma lipoproteins and apolipoproteins were determined and PON1 activity was measured using paraoxon as a substrate. High-resolution β-mode ultrasonography was used to measure cIMT and the presence of carotid atherosclerotic plaques in a subgroup of individuals (n = 317).Results:The presence of p.192Q was associated with a significant increase in PON1 activity (RR = 12.30 (11.38); RQ = 46.96 (22.35); QQ = 85.35 (24.83) μmol/min; p < 0.0001), HDL-C (RR= 45 (37); RQ = 62 (39); QQ = 69 (29) mg/dL; p < 0.001) and apo A-I (RR = 140.76 ± 36.39; RQ = 147.62 ± 36.92; QQ = 147.49 ± 36.65 mg/dL; p = 0.019). Stepwise regression analysis revealed that heterozygous and p.192Q carriers influenced by 58% PON1 activity towards paraoxon. The univariate linear regression analysis demonstrated that p.Q192R SNP was not associated with mean cIMT; as a result, in the multiple regression analysis, no variables were selected with 5% significance. In logistic regression analysis, the studied parameters were not associated with the presence of carotid plaques.Conclusion:In low-risk individuals, the presence of the p.192Q variant ofPON1 is associated with a beneficial plasma lipid profile but not with carotid atherosclerosis.

In molluscs, internal defence against microorganisms is performed by a single cell type, i.e., the haemocyte or amoebocyte. The origin of these cells in Biomphalaria glabrata was initially thought to be localised within the vasculo-connective tissue. More recently, origin from a single organ, termed the amoebocyte-producing organ (APO), has been postulated based on the occurrence of hyperplasia and mitoses during Schistosoma mansoni infection. The present investigation represents a histological, immuno-histochemical and ultra-structural study of the B. glabrata APO, whereby histological identification was facilitated by means of collecting epithelial basophilic cells. These cells were comprised of single-cell layers that cover a portion of the stroma, which contains many small, round cells and haemolymph sinuses, as well as a small area of the pericardial surface of the reno-pericardial region. On occasion, this epithelial component vaguely resembled the vertebrate juxtaglomerular apparatus, which reinforces its presumed relationship to the kidney. Both in normal and infected molluscs, mitoses were only occasionally found. The present quantitative studies failed to demonstrate the presence of APO cellular hyperplasia, either in normal or schistosome-infected B. glabrata. Conversely, several structural details from the APO region in B. glabrata were found to be consistent with the hypothesis that the APO is a filtration organ, i.e., it is more closely related to the kidney rather than the bone marrow, as has been suggested in the literature.

OBJETIVO: Avaliar se perfil lipídico (PL), apolipoproteína A-1 (apo A-I) e malondialdeído (MDA) têm relação com atividade física comparando os grupos: jogadores de futebol (FG) com indivíduos sedentários (CG) e seus familiares. SUJEITOS E MÉTODOS: Foram avaliados 20 indivíduos de FG e CG, além de 60 familiares de FG (RFG) e 57 de CG (RCG). RESULTADOS: FG mostrou menores níveis (média ± DP [mg/dL]) de colesterol total (119.5 ± 37.9), LDL colesterol (53.6 ± 30.3), e apo A-I (116.7 ± 11.9), e maiores níveis de HDL colesterol (HDLc) (49.7 ± 8.5) comparado ao RFG (148.3 ± 36.9, P = 0.02; 82.4 ± 37.7, P < 0.01; 124.6 ± 10.2, P = 0.03; e 42.7 ± 7.7, P < 0.01; respectivamente). Além disso, o FG mostrou níveis reduzidos de MDA (101.0 ± 77.0 [ng/mL]) comparado a CG (290.0 ± 341.0, P = 0.03) e RFG (209.9 ± 197.5, P = 0.04). CONCLUSÕES: Esses resultados sugerem que existe uma associação entre atividade física e níveis reduzidos de MDA em FG. O exercício físico parece promover efeitos benéficos no PL independente da influência genética considerando os níveis de HDLc.

OBJECTIVE: To evaluate whether lipid profile (LP), apolipoprotein A-1 (apo A-I) and malondialdehyde (MDA) have any relationship with physical exercise by comparing the groups of footballers (FG) with sedentary individuals (CG) and their relatives (RFG and RCG). SUBJECTS AND METHODS: Twenty individuals from FG and CG, 60 from RFG, and 57 from RCG were studied. RESULTS: FG showed lower levels of total cholesterol (119.5 ± 37.9 mg/dL), LDL-cholesterol fraction (53.6 ± 30.3), apo A-I (116.7 ± 11.9), and higher level of HDL-cholesterol fraction (HDLc) (49.7 ± 8.5) compared to RFG (148.3 ± 36.9, P = 0.02; 82.4 ± 37.7, P < 0.01; 124.6 ± 10.2, P = 0.03; and 42.7 ± 7.7, P < 0.01; respectively). Moreover, FG had reduced levels of MDA (101.0 ± 77.0 ng/mL) compared to CG (290.0 ± 341.0, P = 0.03) and RFG (209.9 ± 197.5, P = 0.04). CONCLUSIONS: These results suggest an association between physical exercise and lower levels of MDA in FG. Physical activity seems to promote beneficial effects on the LP regardless of the genetic influence considering HDLc levels.

INTRODUÇÃO: A apolipoproteína E (apo E) é reconhecida como fator de risco para doença de Alzheimer (DA). OBJETIVO: Analisar o polimorfismo da apo E nos familiares em primeiro grau de pacientes com DA familial ou esporádica do tipo tardio, comparando a famílias sem DA. MÉTODO: Foram estudados 40 pacientes com DA familial ou esporádica do tipo tardio, sendo os grupos classificados como provável, segundo critérios da NINCS-ADRDA. RESULTADO: O alelo épsilon3 foi o mais freqüente em todos os grupos. Observou-se freqüência mais elevada de épsilon4 comparando os familiares dos probandos aos do grupo controle (p<0,0001). O alelo épsilon2 mostrou diferença significante apenas entre familiares do grupo controle e DA familial (p=0,026). CONCLUSÃO: O polimorfismo da apo E não diferencia DA familial da esporádica. O estudo de famílias permite amplificar a representatividade dos alelos épsilon2 e épsilon4, revelando, seu valor como fator protetor e de risco para DA, respectivamente.

INTRODUCTION: Apolipoproteín E (apo E) has been recognized as a risk factor for Alzheimer disease (AD). OBJECTIVE: To analyze apo E polymorphism in first-degree relatives of patients with familial or sporadic late-onset AD comparing with families without AD. METHOD: Forty patients with familial or sporadic late-onset of AD, being both groups classified as probable, according of NINCS-ADRDA’s criteria. RESULTS: Allele epsilon3 was the most frequent in all of these groups. Higher frequency of epsilon4 when comparing the relatives of the probands with the relatives of the control group (p<0,0001) was observed. Allele epsilon2 showed significant difference only between relatives of familial AD and relatives of control group (p=0,026). CONCLUSION: Apo E polymorphism has not differentiated familial from sporadic AD. The study of families allows to amplify the alelles epsilon2 and epsilon4 representativity, revealing, their value as protecting factor and of risk for AD, respectively.

A histologic, morphometric and ultrastructural study performed on Biomphalaria glabrata submitted to infection with Schistosoma mansoni miracidia failed to provide significant evidences that the so-called amebocyte-producing organ (APO) is really the central organ for hemocyte production. In infected snails no general reactive changes appeared in the APO, the mitoses were seen only occasionally, and the possibility of cellular hyperplasia was ruled out by morphometric measurements. Under the electron microscope the APO cells presented an essentially epithelial structure, without features indicative of transition toward hemocytes. On the other hand, the present findings pointed to a multicentric origin for the mollusck hemocytes, as earlier studies had indicated. Dense foci of hemocyte collections appeared sometimes around disintegrating sporocysts and cercariae in several organs and tissues of the infected snails, including a curious accumulation of such cells inside the ventricular cavity of the heart. In the heart and other sites, features suggestive of transformation of vascular space endothelial lining cells into hemocytes were apparent. To some extent, the postulated multicentric origin for B. glabrata hemocytes recapitulates earlier embryologic findings in vertebrates, when mesenchymal vascular spaces generate the circulating and phagocytic blood cells.

A heterogeneidade genética da apolipoproteína E (apo E) tem sido associada com o perfil lipídico e acidente vascular cerebral aterotrombótico (AVC at); no entanto, esta associação permanece inconclusiva. OBJETIVO: Avaliar a relação entre as isoformas da apo E e o AVC at pela determinação da frequência de seus alelos e genótipos, associados ao perfil lipídico, em pacientes com a doença. MÉTODO: Foram estudados 207 indivíduos distribuídos em 2 grupos, consistindo de 107 pacientes com AVC e 100 indivíduos sem sintomas clínicos da doença. Amostras de sangue periférico foram obtidas de pacientes e controles para investigação molecular da apo E (alelos épsilon2, épsilon3 e épsilon4) e para análise do perfil lipídico. RESULTADOS: O alelo épsilon3 foi o mais comum e sua prevalência foi significantemente mais elevada em pacientes (0,93) comparada com controles (0,86; p=0,024). O alelo épsilon2 foi raramente encontrado, especialmente em pacientes (0,02 versus 0,05 em controles; p=0,191). A presença do alelo épsilon4 não foi associada com AVC, apresentando frequência reduzida em pacientes (0,05) quando comparada com controles (0,09; p=0,011). Apesar de níveis médios elevados do perfil lipídico terem sido encontrados em pacientes quando comparados com controles, com significância estatística para valores de colesterol total (CT) (203,6md/dL±57,98, e 181,9mg/dL±68,47, respectivamente; p=0,003) e colesterol de baixa densidade (LDLc) (131,4mg/dL±52,60 e 116mg/dL±56,38, respectivamente; p=0,014), esses resultados se mostraram independentes da presença do alelo épsilon4. No grupo controle, os valores mais elevados de CT e LDLc ocorreram na ausência do alelo épsilon4, confirmando o efeito conflitante dos alelos da apo E sobre os lipídios plasmáticos e sobre o AVC at. CONCLUSÃO: As isoformas da apo E não podem ser consideradas fator de risco isolado para AVC at e não mostram associação com o perfil lipídico neste estudo.

The genetic heterogeneity of apolipoprotein E (apo E) has been associated with lipid profile and atherothrombotic stroke, however this association remains inconclusive. OBJECTIVE: To evaluate the relationship between the isoforms of apo E and atherothrombotic stroke, by ascertaining the frequency of its alleles and genotypes associated with the lipid profile in patients with stroke. METHOD: A total of 207 individuals were divided into two groups, consisting of 107 patients with stroke and 100 individuals without clinical symptoms of the disease. Blood samples were taken from patients and controls for molecular investigation of the apo E (epsilon2, epsilon3 and epsilon4 alleles) for the analysis of the lipid profile. RESULTS: The epsilon3 allele was the most common and its prevalence was significantly higher in patients (0.93) compared to the controls (0.86; p=0.024). The epsilon2 allele was rarely seen specifically in patients (0.02 versus 0.05 in controls, p=0.191). The epsilon4 allele was not associated with stroke showing a reduced frequency in patients (0.05) when compared to controls (0.09; p=0.011). Although higher average levels of lipid profile were found in patients when compared to controls, with statistical significance for the values of total cholesterol (TC) (203.6mg/dL±57.98 and 181.9mg/dL±68.47 respectively; p=0.003) and low-density lipoprotein cholesterol (LDLc) (131.4mg/dL±52.60 and 116mg/dL±56.38, respectively; p=0.014), these were independent of the presence of the epsilon4 allele. In control group the higher TC and LDLc values occurred in the absence of the epsilon4 allele, confirming the conflicting effect of the alleles of apo E on the plasmatic lipids and atherothrombotic stroke. CONCLUSION: The isoforms of apo E cannot be regarded as an isolated risk factor for stroke and do not show association with lipid profile in this study.

OBJECTIVE: To evaluate whether apolipoproteins A-I (Apo A-I) and B (Apo B) have, higher ensitivity (SN), specificity (SP) and positive predictive value (PPV) than lipoproteins (LP), total cholesterol (TC), high density lipoprotein (HDL), low density lipoprotein (LDL), very low density lipoprotein (VLDL), and triglycerides (TGL) in assessing the risk of coronary heart disease (CHD). METHODS: This is a transversal case-control study of 241 patients, who were divided into two groups: 1) 145 patients with CHD, and 2) 96 patients without coronary disease. A model of logistic regression to evaluate the relation between the LPs and CHD was developed in which variables with a p-alpha <0.1 were included. RESULTS: Apo A-I levels were higher in the patients without CHD, (OR 2.08, CI 1.20-3.57). There were no statistical differences between the values of Apo A-I and the remaining lipid fractions (Apo A-I: 67%; Apo B: 100%; PPV: TC= 71%; TGC=71%; HDL=71%; LDL=71%). The costs of the tests in Reais were as follows: Apo A-I: R$ 56.60; Apo B-100: R$ 56.60; TC: R$ 9.94; HDL: R$ 21.30; LDL: R$ 28.40; TGL: R$ 14.20. CONCLUSION: Levels of Apo A-I and Apo B have no advantage over conventional lipoproteins in predicting the risk of CHD, despite the statistical association between Apo A-I and CHD; in addition, their costs are higher than those of the conventional lipoproteins.