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ABSTRACT This article aims to analyze scientific articles about School and Educational Psychology, specifically related to the training of psychologists. We carried out a systematic review of articles (2009-2019), using the Portal Periódicos CAPES platform, using the descriptors “school psychology AND psychologist training” and “educational psychology AND psychologist training”. After applying the inclusion and exclusion criteria and identifying repeated articles, we proceeded with the selection by reading the publications, resulting in a total of 26 articles, mostly published in the Revista de Psicologia Escolar e Educational. In the discussions, we identified the use of traditional practices, clinical instruments and clinical practices as a questioning point related to forms of stigmatization and the absence of theoretical references specific to School Psychology. As for training in the area, questions emerge about initial and continuing training, little curricular space for School Psychology and Historical-Cultural Psychology as a methodological alternative for action.

RESUMEN Este texto tiene por objetivo analizar artículos científicos sobre Psicología escolar/educacional, específicamente relacionados a la formación de psicólogos. Realizamos una revisión sistemática de artículos (2009-2019), por la plataforma Portal Periódicos CAPES, utilizando los descriptores “psicología escolar AND formación del psicólogo” y “psicología educacional AND formación del psicólogo”. Tras aplicar los criterios de inclusión y exclusión e identificación de artículos repetidos, procedemos la selección por la lectura de las publicaciones, resultando en un total de 26 artículos, en su mayoría publicados en la Revista de Psicología Escolar/Educacional. En las discusiones, identificamos el uso de prácticas tradicionales, de instrumentales y prácticas clínicos como punto de problematización relacionado a las formas de estigmatización y a la ausencia de referenciales teóricos propios de la Psicología Escolar. En lo que se refiere a la formación en el área, emergen cuestiones sobre formación inicial y continuada, poco espacio curricular para Psicología escolar y la Psicología Histórico-Cultural como alternativa metodológica para actuación.

RESUMO Este texto objetiva analisar artigos científicos sobre Psicologia Escolar/Educacional, especificamente relacionados à formação de psicólogos. Realizamos uma revisão sistemática de artigos (2009-2019), pela plataforma Portal Periódicos CAPES, mediante os descritores “psicologia escolar AND formação do psicólogo” e “psicologia educacional AND formação do psicólogo”. Após a aplicação dos critérios de inclusão e exclusão e identificação de artigos repetidos, procedemos à seleção pela leitura das publicações, resultando um total de 26 artigos, em sua maioria publicados na Revista de Psicologia Escolar e Educacional. Nas discussões, identificamos o uso de práticas tradicionais, de instrumentais clínicos e práticas clínicas como ponto de problematização relacionado às formas de estigmatização e a ausência de referenciais teóricos próprios da Psicologia Escolar. Quanto à formação na área, emergem questões sobre formação inicial e continuada, pouco espaço curricular para Psicologia Escolar e a Psicologia Histórico-Cultural como alternativa metodológica para atuação.

https://doi.org/10.1590/2175-35392023-243249

Understanding the Deliberation Practice in a Controllership from the Performative Judgement Perspective
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Russo, Paschoal Tadeu

; Leandro, José Roberto

; Borinelli, Márcio Luiz

; Souza, Rodrigo Paiva

Organizações & Sociedade

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Jun 2022, Volume 29 Nº 101 Páginas 351 - 384

Resumo: Pt En | Texto: Pt En | PDF: Pt | PDF: En

Resumo Bispo (2015)

Abstract This research analyzed deliberation practice in a controllership, mainly the decision to replace a given budgetary practice by another, in light of performative judgements, in a big-sized company in São Paulo City, between 2017 and 2020. The research followed the interpretative design, and adopted the research-action strategy. Participatory observation, in-depth interviews (initial research stage) and documental analyses were the techniques applied to find evidences. The field zooming in and zooming out movements were used to describe the elements featuring this practice, by switching the theoretical lens to better understand the whole and the elements composing it. Data analysis followed the framework proposed by Bispo (2015). We have found four fragments of practices encompassing the material arrangements where deliberation takes place: financial management practice, accounting management practice, expense management practice and information technology management practice. Different from the accountability management mainstream, which assumes rationality driven by economic aims, we have observed that deliberation in the assessed controllership is boosted by the “rationality of becoming” as permanent flow. Such a rationality is collectively built due to practical wisdom and to the ability of making practical decisions that form wisdom and practical judgements. It simultaneously shows its fragility in comparison to what is expected from the economic paradigm, as well as its richness, by encompassing the pluralism and dynamics of the context it is inserted in.

https://doi.org/10.1590/1984-92302022v29n0015en

Amphibians and reptiles from a protected area in western Brazilian Amazonia (Reserva Extrativista do Baixo Juruá)
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Moraes, Leandro João Carneiro de Lima

; Rainha, Raíssa do Nascimento

; Werneck, Fernanda de Pinho

; Oliveira, Alan Filipe de Souza

; Gascon, Claude

; Carvalho, Vinícius Tadeu de

Papéis Avulsos de Zoologia

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2022, Volume 62 elocation e202262054

Resumo: En | Texto: En | PDF: En

Abstract Sampling gaps across the logistically challenging and extremely biodiverse Amazonia largely hamper our understanding of broad-scale amphibian and reptile diversity patterns in this ecosystem. The Juruá River basin, a southwestern tributary of the Amazon River, is one of these undersampled areas, with only punctual information documented for these vertebrates that are spatially or temporally biased. This is especially the case for the lower-middle courses of the Juruá River, which also has comparatively less protected areas than its upper course. In order to fill some biodiversity knowledge gaps associated with amphibians and reptiles in this river basin, we combined results of our field expeditions carried out in 1992, 2005-2007, and 2018 to the Reserva Extrativista (Extractive Reserve) do Baixo Juruá, a Brazilian protected area in the right bank of the lower Juruá River. Amphibians and reptiles were sampled using four complementary methods: active surveys, pitfall traps, funnel traps, and trammel nets. We identified species or updated their taxonomic status with a reanalysis of the external morphology of the preserved material in the light of novel taxonomic literature (more than 1,500 specimens) and employment of DNA barcoding analyses for some newly collected specimens with contentious taxonomic status. Our combined sampling evidenced 149 species of amphibians and reptiles occurring in this protected area (72 amphibians, 68 squamates, six chelonians, and three crocodilians). Recorded species highlight the value of the lower Juruá River region as harboring quite diverse assemblages for these vertebrates, with species typical of the western and southwestern Amazonia sub-regions. Remarkable species records are presented, as well as accounts on species with lower taxonomic resolution. Furthermore, we discuss the biogeographic affinities of recorded assemblages based on the species geographic range and preferred habitats, and the value of this protected area to preserve the regional biological diversity.

https://doi.org/10.11606/1807-0205/2022.62.054

Hepatocellular carcinoma (HCC) in patients with Non-Alcoholic Fatty Liver Disease (NAFLD): screening, treatment and survival analysis in a Brazilian series
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Alencar, Regiane Saraiva de Souza Melo

; Oliveira, Claudia P.

; Chagas, Aline Lopes

; Fonseca, Leonardo Gomes da

; Maccali, Claudia

; Saud, Lisa Rodrigues da Cunha

; Xerfan, Mariana Pinheiro

; Stefano, Jose Tadeu

; Herman, Paulo

; D'Albuquerque, Luiz Augusto Carneiro

; Alves, Venâncio Avancini Ferreira

; Carrilho, Flair Jose

Clinics

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2022, Volume 77 elocation 100097

Resumo: En | Texto: En | PDF: En

Abstract Objective: The aim of the present study was to evaluate the clinical features, Hepatocellular Carcinoma (HCC) screening, treatment modalities, and Overall Survival (OS) in a series of Non-Alcoholic Fatty Liver Disease-Related Hepatocellular Carcinoma (NAFLD-HCC) Brazilian patients. Methods: This was a cross-sectional study at the Instituto do Cancer do Estado de São Paulo, at the Faculdade de Medicina da Universidade de São Paulo with the approval of the local research ethics committee. NAFLD patients with HCC diagnosed, from May 2010 to May 2019, were included. Results: A total of 131 patients were included. Risk factors for NAFLD were present in 94.7% of the patients. Only 29% of patients were in the HCC screening program before diagnosis. HCC treatment was performed in 84.7% of patients. Cumulative survival at the end of the first year was 72%, second-year 52%, and fifth-year 32%. HCC screening before diagnosis was not significantly associated with higher cumulative survival. The independent factors associated with shorter general survival were BCLC C-D, p < 0.001, and the size of the largest nodule > 42 mm, p = 0.039. Conclusions: Although the efficacy of screening in our population regarding overall survival was hampered due to the sample size (29% had screening), BCLC stages C‒D and the size of the largest nodule larger than 42 mm were identified as independent factors of worse prognosis.

https://doi.org/10.1016/j.clinsp.2022.100097

Evidências sobre modelos de gestão em enfermagem nos serviços hospitalares: revisão integrativa
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Silva, Gilberto Tadeu Reis da

; Góis, Rebecca Maria Oliveira de

; Almeida, Deybson Borba de

; Santos, Thadeu Borges Souza

; Cantarino, Maria Sagrario Gómez

; Queirós, Paulo Joaquim Pina

; Amestoy, Simone Coelho

Acta Paulista de Enfermagem

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2021, Volume 34 elocation eAPE002095

Resumo: Pt En Es | Texto: Pt En Es | PDF: Pt | PDF: En | PDF: Es

Resumo Objetivo Identificar, avaliar e sumarizar as evidências científicas sobre os modelos de gestão em enfermagem nos serviços hospitalares entre os anos de 2013 e 2019. Métodos Trata-se de uma revisão integrativa da literatura realizada nas bases de dados Web of Science, Centro Latino-Americano e do Caribe de Informação em Ciências da Saúde – BIREME/ BVS, National Library of Medicine (PubMed/MEDLINE), Education Resources Information Center (Eric) e na biblioteca Scientific Electronic Library Online (SciElo), entre os anos de 2013 e 2019. Resultados Dos 100 estudos encontrados nas bases, 16 foram selecionados para análise, após aplicação dos critérios de inclusão e exclusão. Destes, 14 (87,5%) produções eram internacionais e duas (12,5%) nacionais. Seis publicações (37,5%) eram originárias dos Estados Unidos da América, dois (12,5%) artigos brasileiros e outros dois (12,5%) provenientes da Itália. África, Portugal, Inglaterra, Alemanha, China e Canadá tiveram um artigo (6,2%) cada. As evidências relacionadas aos modelos de gestão adotados por enfermeiros no ambiente hospitalar foram sistematizadas em três categorias: Gestão com foco na melhoria do cuidado; Gestão com ênfase na eficiência dos serviços; e Gestão voltada aos custos hospitalares. Essas categorias evidenciam uma diversidade de modelos adotados na gestão hospitalar sob liderança de enfermeiros. Conclusão O estudo indica a existência de modelos de gestão na perspectiva da melhoria continuada dos processos assistenciais e de fortalecer a prática profissional do enfermeiro na produção de cuidados, a fim de garantir uma assistência livre de danos e, sobretudo, a satisfação de clientes e trabalhadores. Sinaliza-se a diversidade de Modelos de Gestão.

Abstract Objective To identify, assess, and summarize the scientific evidence on nursing management models in hospital services between 2013 and 2019. Methods This is an integrative literature review carried out in the Web of Science, Latin American and Caribbean Center for Health Sciences Information, BIREME/VHL, National Library of Medicine (PubMed/MEDLINE), Education Resources Information Center (Eric), and Scientific Electronic Library Online (SciElo) databases between 2013 and 2019. Results Of the 100 studies found in the databases, 16 were selected for analysis after applying the inclusion and exclusion criteria. Of these, 14 (87.5%) productions were international and two (12.5%) were national. Six publications (37.5%) were from the United States of America, two (12.5%) were Brazilian articles and two (12.5%) were from Italy. Africa, Portugal, England, Germany, China and Canada had one article (6.2%) each. The evidence related to the management models adopted by nurses in the hospital environment was systematized into three categories: Management focused on improving care; Management focused on service efficiency; Management focused on hospital costs. These categories show a diversity of models adopted in hospital management under the leadership of nurses. Conclusion The study indicates the existence of management models in the perspective of continuous improvement of care processes and to strengthen the professional practice of nurses in production of care, in order to guarantee harm-free care and, above all, customer and worker satisfaction. The diversity of management models is highlighted.

Resumen Objetivo Identificar, analizar y resumir las evidencias científicas sobre los modelos de gestión en enfermería en servicios hospitalarios entre los años 2013 y 2019. Métodos Se trata de una revisión integradora de la literatura realizada en las bases de datos Web of Science, Centro Latinoamericano y del Caribe de Información en Ciencias de la Salud – BIREME/ BVS, National Library of Medicine (PubMed/MEDLINE), Education Resources Information Center (Eric) y en la biblioteca Scientific Electronic Library Online (SciElo), entre los años 2013 y 2019. Resultados De los 100 estudios encontrados en las bases, 16 fueron seleccionados para el análisis, luego de aplicar los criterios de inclusión y exclusión. Entre estas producciones, 14 (87,5 %) eran internacionales y dos (12,5 %) nacionales. Seis publicaciones (37,5 %) eran originarias de los Estados Unidos de América, dos (12,5 %) artículos brasileños y otros dos (12,5 %) provenientes de Italia. África, Portugal, Inglaterra, Alemania, China y Canadá tuvieron un artículo (6,2 %) cada uno. Las evidencias relacionadas con los modelos de gestión adoptados por enfermeros en el ambiente hospitalario fueron sistematizadas en tres categorías: Gestión con foco en la mejora del cuidado, Gestión con énfasis en la eficiencia de los servicios y Gestión orientada a los costos hospitalarios. Estas categorías demuestran una diversidad de modelos adoptados en la gestión hospitalaria bajo liderazgo de enfermeros. Conclusión El estudio indica la existencia de modelos de gestión en la perspectiva de la mejora continua de los procesos asistenciales y de fortalecer la práctica profesional del enfermero en la producción de cuidados, a fin de garantizar una atención libre de daños y, sobre todo, la satisfacción de clientes y trabajadores. Se observa una diversidad de modelos de gestión.

https://doi.org/10.37689/acta-ape/2021ar02095 1 downloads

Plasmodium vivax metacaspase 1 (PvMCA1) catalytic domain is conserved in field isolates from Brazilian Amazon
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de Souza, Hugo Amorim dos Santos

; Escafa, Victor Fernandes

; Blanco, Carolina Moreira

; Baptista, Bárbara de Oliveira

; de Barros, Jenifer Peixoto

; Riccio, Evelyn Ketty Pratt

; Rodrigues, Aline Beatriz Mello

; Melo, Gisely Cardoso de

; Lacerda, Marcus Vinícius Guimarães de

; de Souza, Rodrigo Medeiros

; Lima-Junior, Josué da Costa

; Guimarães, Ana Carolina Ramos

; da Mota, Fabio Faria

; da Silva, João Hermínio Martins

; Daniel-Ribeiro, Cláudio Tadeu

; Pratt-Riccio, Lilian Rose

; Totino, Paulo Renato Rivas

Memórias do Instituto Oswaldo Cruz

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2021, Volume 116 elocation e200584

Resumo: En | Texto: En | PDF: En

In the present study, we investigated the genetic diversity of Plasmodium vivax metacaspase 1 (PvMCA1) catalytic domain in two municipalities of the main malaria hotspot in Brazil, i.e., the Juruá Valley, and observed complete sequence identity among all P. vivax field isolates and the Sal-1 reference strain. Analysis of PvMCA1 catalytic domain in different P. vivax genomic sequences publicly available also revealed a high degree of conservation worldwide, with very few amino acid substitutions that were not related to putative histidine and cysteine catalytic residues, whose involvement with the active site of protease was herein predicted by molecular modeling. The genetic conservation presented by PvMCA1 may contribute to its eligibility as a druggable target candidate in vivax malaria.

https://doi.org/10.1590/0074-02760200584 202 downloads

Assessment of premature mortality for noncommunicable diseases
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Istilli, Plinio Tadeu

; Teixeira, Carla Regina de Souza

; Zanetti, Maria Lúcia

; Lima, Rafael Aparecido Dias

; Pereira, Marta Cristiane Alves

; Ricci, Waleska Zafred

Revista Brasileira de Enfermagem

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2020, Volume 73 Nº 2 elocation e20180440

Resumo: En Es Pt | Texto: En Es Pt | PDF: En | PDF: Es | PDF: Pt

ABSTRACT Objectives: to analyze premature mortality and Potential Years of Life Lost by noncommunicable diseases in a city in the countryside of São Paulo from 2010 to 2014. Methods: ecological study of temporal tendency, using secondary source. For analysis, the premature mortality coefficient and the Potential Years of Life Lost indicator were used. Results: males had the highest premature mortality rate due to cardiovascular disease, with 213.04 deaths per 100 thousand inhabitants, followed by neoplasms, with 188.44. In women, there was an inversion with 134.22 deaths from cancer and 110.71 deaths from cardiovascular disease. Regarding Potential Years of Life Lost, males had an average of 12.19 years lost by death and females of 13.45 years lost. Conclusions: the results reinforce the need to increase public health prevention and promotion policies to reduce premature deaths, especially among men.

RESUMEN Objetivos: analizar la mortalidad prematura y los Años Potenciales de Vida Perdidos por enfermedades crónicas no transmisibles en una ciudad del interior de São Paulo, de 2010 a 2014. Métodos: Estudio ecológico de tendencia temporal, utilizando fuente secundaria. Para el análisis, se utilizaron el coeficiente de mortalidad prematura y el indicador de Años Potenciales de Vida Perdidos. Resultados: los hombres tuvieron la tasa de mortalidad prematura más alta debido a enfermedades cardiovasculares, con 213.04 muertes por cada 100 mil habitantes, seguidos de neoplasias, con 188.44. En las mujeres, hubo una inversión con 134.22 muertes por cáncer y 110.71 muertes por enfermedad cardiovascular. Con respecto a los posibles Años Potenciales de Vida Perdidos, los hombres tenían un promedio de 12,19 años perdidos por muerte y las mujeres de 13,45 años perdidos. Conclusiones: los resultados refuerzan la necesidad de aumentar la prevención pública y las políticas de promoción de la salud para reducir las muertes prematuras, especialmente entre los hombres.

RESUMO Objetivos: analisar a mortalidade prematura e os Anos Potenciais de Vida Perdidos por doenças crônicas não transmissíveis, em uma cidade do interior de São Paulo, no período de 2010 a 2014. Métodos: estudo ecológico, de tendência temporal, utilizando-se fonte secundária. Para análise, utilizou-se o coeficiente de mortalidade prematura e indicador de Anos Potenciais de Vida Perdidos. Resultados: o sexo masculino apresentou maior coeficiente de mortalidade prematura por doença cardiovascular, com 213,04 óbitos por 100 mil habitantes, seguido por neoplasias, com 188,44. Nas mulheres, houve uma inversão com 134,22 óbitos por neoplasias e 110,71 óbitos causados pelas doenças cardiovasculares. Em relação aos Anos Potenciais de Vida Perdidos, o sexo masculino apresentou média de 12,19 anos perdidos por óbito e o sexo feminino de 13,45 anos perdidos. Conclusões: os resultados reforçam a necessidade de incrementar políticas públicas de prevenção e promoção de saúde para redução de mortes prematuras, em especial dos homens.

https://doi.org/10.1590/0034-7167-2018-0440 60 downloads

Assessment of premature mortality for noncommunicable diseases
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Istilli, Plinio Tadeu

; Teixeira, Carla Regina de Souza

; Zanetti, Maria Lúcia

; Lima, Rafael Aparecido Dias

; Pereira, Marta Cristiane Alves

; Ricci, Waleska Zafred

Revista Brasileira de Enfermagem

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2020, Volume 73 Nº 2 elocation e20180440

Resumo: Pt En Es | Texto: Pt En Es | PDF: Pt | PDF: En | PDF: Es

https://doi.org/10.1590/0034-7167-2018-0440 1534 downloads

Austrolimnius cleidecostae, a new species of riffle beetle (Coleoptera: Elmidae) from Brazil with habitat notes and updated key of the Brazilian species of the genus
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Polizei, Thiago Tadeu Silva

; Costa, Lucas de Souza Machado

; Bispo, Pitágoras da Conceição

Papéis Avulsos de Zoologia

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2020, Volume 60 Nº spe elocation e202060(s.i.).12

Resumo: En | Texto: En | PDF: En

Abstract Austrolimnius cleidecostae sp. nov. is one of the smallest species of Elmidae from the Neotropical region. The new species is described and illustrated based on male and female specimens. This species represents the first record in Elmidae of mandibles with an articulated, sclerotized process on inner subapical edge. The specimens were collected from streams in the Atlantic rainforest of São Paulo and Santa Catarina, and habitat notes are given. An updated key for the AustrolimniusCarter & Zeck, 1929 of Brazil is provided. Austrolimnis browniHinton, 1971 and A. musgraveiHinton, 1939 are recorded for the first time from Brazil.

https://doi.org/10.11606/1807-0205/2020.60.special-issue.12 327 downloads

10.

EVALUATION OF USABILITY OF A NEONATAL HEALTH INFORMATION SYSTEM ACCORDING TO THE USER’S PERCEPTION
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Padrini-Andrade, Lucio

; Balda, Rita de Cássia Xavier

; Areco, Kelsy Catherina Nema

; Bandiera-Paiva, Paulo

; Nunes, Marynéa do Vale

; Marba, Sérgio Tadeu Martins

; Carvalho, Werther Brunow de

; Rugolo, Ligia Maria Suppo de Souza

; Almeida, João Henrique Carvalho de

; Procianoy, Renato Soibelmann

; Duarte, José Luiz Muniz Bandeira

; Rego, Maria Albertina Santiago

; Ferreira, Daniela Marques de Lima Mota

; Alves Filho, Navantino

; Guinsburg, Ruth

; Diniz, Edna Maria de Albuquerque

; Santos, Juliana Paula Ferraz dos

; Testoni, Daniela

; Silva, Nathalia Moura de Mello e

; Gonzales, Maria Rafaela Conde

; Silva, Regina Vieira Cavalcante da

; Meneses, Jucille

; Gonçalves-Ferri, Walusa Assad

; Perussi-e-Silva, Ricardo

; Bomfim, Olga

Revista Paulista de Pediatria

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Jan 2019, Volume 37 Nº 1 Páginas 90 - 96

Resumo: Pt En | Texto: Pt En | PDF: Pt | PDF: En

RESUMO Objetivo: Mensurar o grau de satisfação de profissionais de saúde quanto à usabilidade de um sistema de informação em saúde neonatal e identificar os fatores que podem influenciar na satisfação do usuário frente à usabilidade. Métodos: Estudo transversal e exploratório realizado com 50 profissionais de saúde integrantes dos centros da Rede Brasileira de Pesquisas Neonatais. Para avaliação da usabilidade foi utilizado o instrumento System Usability Scale entre fevereiro e março de 2017. Realizou-se a análise estatística descritiva e inferencial das variáveis coletadas, com a finalidade de descrever a amostra, quantificar o grau de satisfação dos usuários e identificar as variáveis associadas ao grau de satisfação do usuário em relação à usabilidade. Resultados: Da população avaliada, 75% era do sexo feminino, com idade média 52,8 anos, 58% com pós-graduação (doutorado); tempo médio da última formação de 17 anos; área de atuação em medicina (neonatologia), grau intermediário de conhecimento em informática e tempo de utilização média do sistema de 52 meses. Quanto à usabilidade, 94% avaliaram o sistema como “bom”, “excelente” ou “melhor impossível”. A usabilidade do sistema não foi associada a idade, sexo, escolaridade, profissão, área de atuação, nível de conhecimento em informática e tempo de uso do sistema. Conclusões: O grau de satisfação do usuário do sistema informatizado de saúde foi considerado bom. Não foram identificados fatores demográficos que influenciassem sua avaliação.

ABSTRACT Objective: To measure the level of satisfaction regarding the usability of a neonatal health information system and identify if demographic factors can influence the usability of a health information system. Methods: A cross-sectional, exploratory study was carried out with a convenience sample of 50 users of the Brazilian Neonatal Research Network. The instrument chosen for the usability evaluation was the System Usability Scale between February and March 2017. The statistical analysis of the collected variables was carried out in order to describe the sample, to quantify the level of satisfaction of the users and to identify the variables associated with the level of satisfaction. Results: The female gender represented 75% of the sample. The mean age was 52.8 years; 58% had a doctoral degree, average time of graduation was 17 years, with area of practice in medicine (neonatology), with intermediate knowledge in computer science (74%) and mean system use time of 52 months. Regarding usability, 94% rated the system as “good”, “excellent” or “better than imaginable”. The usability of the system was not associated with age, gender, education, profession, area of practice, knowledge in computer science and time of system use. Conclusion: The level of satisfaction of the computerized health system user was considered good. No demographic factors were associated with the satisfaction of the users.

https://doi.org/10.1590/1984-0462/;2019;37;1;00019 3877 downloads

11.

Chloroquine and mefloquine resistance profiles are not related to the circumsporozoite protein (CSP) VK210 subtypes in field isolates of Plasmodium vivax from Manaus, Brazilian Amazon
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Pratt-Riccio, Lilian Rose

; Baptista, Bárbara de Oliveira

; Torres, Vanessa Rodrigues

; Bianco-Junior, Cesare

; Perce-Da-Silva, Daiana de Souza

; Riccio, Evelyn Kety Pratt

; Lima-Junior, Josué da Costa

; Totino, Paulo Renato Rivas

; Cassiano, Gustavo Capatti

; Storti-Melo, Luciane Moreno

; Machado, Ricardo Luiz Dantas

; de Oliveira-Ferreira, Joseli

; Banic, Dalma Maria

; Carvalho, Leonardo José de Moura

; Daniel-Ribeiro, Cláudio Tadeu

Memórias do Instituto Oswaldo Cruz

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2019, Volume 114 elocation e190054

Resumo: En | Texto: En | PDF: En

BACKGROUND The central repetitive region (CRR) of the Plasmodium vivax circumsporozoite surface protein (CSP) is composed of a repetitive sequence that is characterised by three variants: VK210, VK247 and P. vivax-like. The most important challenge in the treatment of P. vivax infection is the possibility of differential response based on the parasite genotype. OBJECTIVES To characterise the CSP variants in P. vivax isolates from individuals residing in a malaria-endemic region in Brazil and to profile these variants based on sensitivity to chloroquine and mefloquine. METHODS The CSP variants were determined by sequencing and the sensitivity of the P. vivax isolates to chloroquine and mefloquine was determined by Deli-test. FINDINGS Although five different allele sizes were amplified, the sequencing results showed that all of the isolates belonged to the VK210 variant. However, we observed substantial genetic diversity in the CRR, resulting in the identification of 10 different VK210 subtypes. The frequency of isolates that were resistant to chloroquine and mefloquine was 11.8 and 23.8%, respectively. However, we did not observe any difference in the frequency of the resistant isolates belonging to the VK210 subtypes. MAIN CONCLUSION The VK210 variant is the most frequently observed in the studied region and there is significant genetic variability in the CRR of the P. vivax CSP. Moreover, the antimalarial drug sensitivity profiles of the isolates does not seem to be related to the VK210 subtypes.

https://doi.org/10.1590/0074-02760190054 912 downloads

12.

Prevalence of Physical Inactivity and its Effects on Blood Pressure and Metabolic Parameters in a Brazilian Urban Population
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Rissardi, Geiza da Graça Leite

; Cipullo, José Paulo

; Moreira, Gisela Cipullo

; Ciorlia, Luiz Alberto Souza

; Cesarino, Cláudia Bernardi

; Giollo Junior, Luiz Tadeu

; Zanesco, Angelina

; Vilela-Martin, José Fernando

International Journal of Cardiovascular Sciences

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Dez 2018, Volume 31 Nº 6 Páginas 594 - 602

Resumo: En | Texto: En | PDF: En

Abstract Background: Cardiovascular disease is the leading cause of mortality in the world and physical inactivity represents an important risk factor. Objective: This study aimed to evaluate the prevalence of physical inactivity in the adult population and its effects on blood pressure, blood glucose and lipid profile. Methods: A population-based cross-sectional study with stratified simple random sampling was conducted in 1,717 adults divided by age groups: 18-39, 40-49, 50-59, 60-69 and ≥ 70 years. The participants answered the physical activity questionnaire and were classified as physically active or inactive. The bootstrap statistical method was used to assess physical activity, associated with lipid profile and blood glucose levels. The level of significance was 5%. Results: The prevalence of physical inactivity in the general population was 65.8%. There was a significant difference in the group older than 70 years. There was a significant decrease in physical activity in the group with lower educational level, with a significant difference between social classes AB and C. The prevalence of hypertension was 27.5% among physically inactive and 21.4% among active individuals (p = 0.04). The prevalence of metabolic syndrome was 26.1% in inactive and 16.7% in the active individuals (p = 0.007). Total cholesterol, low-density lipoprotein and triglycerides levels were more elevated in the physically inactive group, which was not observed with high-density lipoprotein levels. Blood glucose was also higher in the inactive group. Conclusion: This study shows a high prevalence of physical inactivity and a positive correlation between risk factors for cardiovascular disease, mainly blood pressure, glucose and lipids profiles. (Int J Cardiovasc Sci. 2018; [online].ahead print, PP.0-0)

https://doi.org/10.5935/2359-4802.20180064 1991 downloads

13.

Seroprevalence of Chikungunya virus in blood donors from Northern and Southeastern Brazil
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Slavov, Svetoslav Nanev

; Otaguiri, Katia Kaori

; Bianquini, Melina Lellis

; Bitencourt, Hellen Tayana Oliveira

; Chagas, Marcia Cristina Munhoz

; Guerreiro, Domingos Sávio de Souza

; Figueiredo, Luiz Tadeu Moraes

; Covas, Dimas Tadeu

; Kashima, Simone

Hematology, Transfusion and Cell Therapy

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Out 2018, Volume 40 Nº 4 Páginas 358 - 362

Resumo: En | Texto: En | PDF: En

ABSTRACT Background: Chikungunya virus, an arbovirus that belongs to the Alphavirus genus of the Togaviridae family, causes a febrile illness accompanied by rash and arthralgia. It is estimated that during outbreaks, the prevalence of Chikungunya virus RNA in viremic blood donations varies between 0.4 and 2.1%; therefore, this virus may be transmitted by transfusion. In Brazil, Chikungunya virus has been claimed to cause extensive outbreaks, however, the seroprevalence of anti-Chikungunya virus IgG among Brazilian blood donors is unknown. Methods: Eight hundred and ninety-seven blood samples were collected from volunteer blood donors in two distant localities long after the Chikungunya virus first appeared in Brazil. In 2015, 442 samples were collected from the Hemotherapy Service of Macapá, Amapá in the northern Brazilian Amazon. To evaluate the dissemination course of the virus in Brazil, in 2016, 455 blood samples were collected from the southeastern region (Blood Center of Ribeirão Preto, Ribeirão Preto, São Paulo). All samples were tested for the presence of anti-Chikungunya virus IgG and viral RNA. Results: One sample (0.2%) obtained from the Hemotherapy Center of Macapá tested positive for anti-Chikungunya virus IgG and no sample from the Blood Center of Ribeirão Preto was seroreactive to anti-Chikungunya virus IgG. All blood donations were Chikungunya virus RNA negative. Conclusions: This study, performed during 2015-2016, indicates that the transfusion risk of Chikungunya virus in this period was low. However, due to the constant advance of this virus in Brazil, further studies during outbreaks are needed to evaluate the presence of Chikungunya virus RNA in blood donations and the respective transfusion-transmission risk.

https://doi.org/10.1016/j.htct.2018.04.002 1686 downloads

14.

Sondas de Discriminação na Avaliação da Aprendizagem de Relações Emergentes Nome-Objeto por Exclusão
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Souza, Leylanne Martins Ribeiro de

; Gil, Maria Stella Coutinho de Alcantara

; Garcia, Lucas Tadeu

Trends in Psychology

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Out 2018, Volume 26 Nº 4 Páginas 2231 - 2248

Resumo: Pt En Es | Texto: Pt En Es | PDF: Pt | PDF: En | PDF: Es

Resumo O responder por exclusão é um padrão de resposta robusto, entretanto, a ocorrência regular da resposta que atesta a relação condicional nome-objeto não corresponde à aprendizagem consistente da relação. Este estudo visou avaliar a aprendizagem de relações nome-objeto, após a emergência da relação condicional no responder por exclusão, empregando sondas de discriminação as quais foram expostas 19 crianças, entre 14 e 25 meses. Discriminações condicionais nome-objeto com estímulos familiares foram ensinadas para compor a linha de base. Sondas controle, de exclusão e de discriminação verificaram respectivamente o controle pela novidade dos estímulos, a emergência da relação nome-objeto e a aprendizagem da relação emergente. Se não ocorresse a aprendizagem da relação emergente, inseria-se o ensino por exclusão. Seis participantes responderam por exclusão. Sondas de discriminação atestaram a aprendizagem de duas relações nome-objeto para três participantes. Um participante respondeu consistentemente com a aprendizagem de duas relações, após o ensino da relação nome-objeto emergente. As sondas de discriminação constituíram-se em medida efetiva da aprendizagem de relações emergentes nome-objeto por crianças pequenas.

Abstract Responding by exclusion is a robust response pattern; however, regular occurrence of responses that attest the name-object conditional relation does not correspond to consistent learning of the relation. This study aimed to evaluate learning of name-object relations, after emergence of the conditional relation in responding by exclusion, through discrimination probes presented to 19 children between 14 and 25 months old. Familiar name-object conditional stimuli were taught as baseline. Control, exclusion, and discrimination probes found control by stimulus novelty, emergence of name-object relation, and learning of emergent relation, respectively. If the learning of the emergent relation did not occur, the teaching by exclusion was inserted. Six participants responded by exclusion. Discrimination probes attested learning of two name-object relations by three participants. One participant's responses were consistent with learning two relations after teaching of emergent name-object relations. Discrimination probes were found to be an effective measure for learning of emergent name-object relations by small children.

Resumen La respuesta por exclusión es un patrón de respuesta robusta. Sin embargo, la ocurrencia regular de la respuesta que da cuenta de la relación condicional nombre-objeto no se corresponde al aprendizaje consistente de dicha relación. Este estudio tuvo como objetivo evaluar el aprendizaje de relaciones nombre-objeto, después de la emergencia de la relación condicional al responder por exclusión, utilizando ensayos de prueba de discriminación a las cuales fueron expuestos 19 niños, de entre 14 y 25 meses. Discriminaciones condicionales nombre-objeto con estímulos familiares se enseñaron para constituir la línea base. Las pruebas de control, exclusión y discriminación verificaron, respectivamente, el control por novedad de los estímulos, la emergencia de la relación nombre-objeto y el aprendizaje de la relación emergente. Si no ocurría el aprendizaje de la relación emergente, se inserta la enseñanza por exclusión. Seis participantes respondieron por exclusión. Las pruebas de discriminación mostraron el aprendizaje de las relaciones nombre-objeto para tres participantes. Un participante respondió consistentemente con el aprendizaje de dos relaciones, después de la enseñanza de la relación nombre-objeto emergente. Las pruebas de discriminación se constituyeron como una medida efectiva del aprendizaje de relaciones emergentes nombre-objeto para niños pequeños.

https://doi.org/10.9788/tp2018.4-19pt 975 downloads

15.

EXPLORING CORTICAL BONE DENSITY THROUGH THE ULTRASOUND INTEGRATED REFLECTION COEFFICIENT
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Matusin, Daniel Patterson

; Fontes-Pereira, Aldo José

; Rosa, Paulo Tadeu Cardozo Ribeiro

; Barboza, Thiago

; Souza, Sergio Augusto Lopes de

; Krüger, Marco Antônio von

; Pereira, Wagner Coelho de Albuquerque

Acta Ortopédica Brasileira

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Ago 2018, Volume 26 Nº 4 Páginas 255 - 259

Resumo: Pt En | Texto: Pt En | PDF: Pt | PDF: En

RESUMO Objetivo: Este estudo avalia a relação entre a reflexão ultrassônica e a densidade óssea de 14 amostras cilíndricas de osso cortical bovino (3,0 cm de espessura). Métodos: Foi realizada a aquisição de 20 sinais de reflexão ultrassônica por amostra (passo de 2,0 mm), ao longo da superfície óssea. O Coeficiente de Reflexão Integrado (IRC) de cada sinal foi comparado por Tomografia Computadorizada Quantitativa (QCT). Resultados: Sete curvas de IRC e QCT apresentaram valor de Correlação R de Pearson acima de 0,5. Para curvas de correlação fraca, QCT e IRC apresentaram tendências semelhantes em vários segmentos. Conclusão: O IRC foi sensível à variação da densidade óssea. Nível de evidência: Estudo Experimental, Investigação de Exame Diagnóstico.

ABSTRACT Objective: This work evaluates the relationship between ultrasonic reflection and bone density from fourteen cylindrical bovine cortical bone samples (3.0-cm thick). Methods: Twenty US reflection signals per sample were acquired along the bone surface (2.0-mm step). The Integrated Reflection Coefficient (IRC) from each signal was compared to Quantitative Computed Tomography (QCT). Results: Seven IRC and QCT curves presented Pearson's Correlation R-values above 0.5. For weak correlation curves, QCT and IRC showed similar trends in several segments. Conclusion: IRC was sensitive to bone density variation. Level of Evidence: Experimental Study, Investigating a Diagnostic Test.

https://doi.org/10.1590/1413-785220182604177202 649 downloads

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