Abstract Introduction: Cardiovascular disease is an important cause of death among patients with chronic kidney disease (CKD). Valve calcification is a predictor of cardiovascular mortality and coronary artery disease. Objective: To assess heart valve disease frequency, associated factors, and progression in CKD patients. Methods: We conducted a retrospective study on 291 CKD patients at Hospital das Clínicas de Pernambuco. Inclusion criteria were age ≥ 18 with CKD and valve disease, while those on conservative management or with missing data were excluded. Clinical and laboratory variables were compared, and patients were categorized by dialysis duration (<5 years; 5–10 years; >10 years). Statistical tests, including chi-square, Fisher’s exact, ANOVA, and Kruskal-Wallis, were employed as needed. Simple and multivariate binary regression models were used to analyze valve disease associations with dialysis duration. Significance was defined as p < 0.05. Results: Mitral valve disease was present in 82.5% (240) of patients, followed by aortic valve disease (65.6%; 86). Over time, 106 (36.4%) patients developed valve disease. No significant association was found between aortic, pulmonary, mitral, or tricuspid valve disease and dialysis duration. Secondary hyperparathyroidism was the sole statistically significant factor for mitral valve disease in the regression model (OR 2.59 [95% CI: 1.09–6.18]; p = 0.031). Conclusion: CKD patients on renal replacement therapy exhibit a high frequency of valve disease, particularly mitral and aortic valve disease. However, no link was established between dialysis duration and valve disease occurrence or progression.

Resumo Introdução: Doenças cardiovasculares são uma causa significativa de morte em pacientes com Doença Renal Crônica (DRC). A calcificação valvar é preditor de mortalidade cardiovascular e doença arterial coronariana. Objetivo: Avaliar a frequência, fatores associados e progressão de valvopatias em pacientes com DRC. Métodos: Coorte retrospectiva com 291 pacientes ambulatoriais no Hospital das Clínicas de Pernambuco. Inclusão: ≥18 anos com DRC e valvopatia; exclusão: tratamento conservador ou dados incompletos. Variáveis clínicas e laboratoriais foram comparadas e categorizadas por tempo de terapia dialítica (TTD): <5 anos, 5–10 anos, >10 anos. Foram aplicados os testes Qui-quadrado, exato de Fisher, ANOVA, Kruskal-Wallis. Associação entre valvopatia e TTD foi avaliada por regressão binária. Significância foi definida como p < 0,05. Resultados: A valvopatia mitral foi encontrada em 82,5% (240) dos casos, seguida da aórtica (65,6%; 86). Houve progressão da doença valvar em 106 (36,4%) pacientes. Não houve associação entre valvopatias aórtica, pulmonar, mitral ou tricúspide e TTD. Hiperparatireoidismo secundário foi a única variável explicativa significativa na regressão para valvopatia mitral (OR 2,59 [IC95%: 1,09–6,18]; p = 0,031). Conclusão: Encontramos alta frequência de valvopatias, especialmente mitral e aórtica, aem pacientes com DRC. Não houve associação entre TTD e valvopatia.

Resumo Introdução Considerada um dos distúrbios neurovas-culares mais comuns entre estudantes universitários, a cefaleia gera impacto na qualidade de vida. Além disso, o estresse e a fadiga podem desencadear e/ou intensificar as dores de cabeça. Objetivo Investigar a relação entre fadiga e estresse em estudantes universitários com cefaleia. Métodos Participaram 147 discentes, na faixa etária de 18 a 44 anos, independente do sexo, regularmente matriculados na Universidade de Fortaleza. Os dados foram coletados por meio de questionário elaborado pelos pesquisadores e por instrumentos validados para o diagnóstico de cefaleia, sendo o impacto mensurado pelo HIT-6 ( Headache Impact Test ), a avaliação da fadiga por meio da Escala de gravidade da fadiga (EGF) e a qualidade de vida através do SF-36. Os dados foram analisados pelo programa SPSS 20.0, utilizando-se o teste de qui-quadrado para analisar a associação entre as variáveis. Adotou-se nível de significância de 5%. Resultados A queixa de dor de cabeça esteve presente em 70,7% da amostra (n = 104), sendo mais predominante a cefaleia secundária (63,5%, n = 66), no sexo feminino (79,8%, n = 83), com média de idade de 21,7 ± 4,0 anos. A intensidade moderada da dor de cabeça foi relatada por 60,6% (n = 63), destacando-se o impacto desta dor como muito grave em 68,3% (n = 71) dos participantes. Constatou-se que os estudantes com cefaleia apresentaram mais sintomas de estresse (30,5 ± 7,6; p < 0,004) e fadiga (4,0 ± 1,4; p < 0,040). Conclusão Encontrou-se um número expressivo de casos de cefaleia, principalmente no sexo feminino, relacionados a sintomas de estresse e fadiga, gerando impacto na qualidade de vida desses universitários.

Abstract Introduction Considered one of the most common neurovascular disorders among university students, headache has an impact on quality of life. In addition, stress and fatigue can trigger and/or intensify headaches. Objective To investigate the relationship between fatigue and stress in university students with headache. Methods One hundred and forty-seven students aged between 18 and 44 years, regardless of gender, and regularly enrolled at the Universidade de Fortaleza participated in the study. Data were collected through a questionnaire developed by the researchers and through validated instruments for the diagnosis of headache, the impact being measured by the HIT-6 (Headache Impact Test), the assessment of fatigue using the Fatigue Severity Scale (FGS), and quality of life through the SF-36. Data were analyzed using the SPSS 20.0 program, using the chi-square test to analyze the association between the variables. A significance level of 5% was adopted. Results Headache complaints were present in 70.7% of the sample (n = 104), with secondary headache being more predominant (63.5%, n = 66), in females (79.8%,n = 83), with a mean age of 21.7 ± 4.0 years. The moderate intensity of the headache was reported by 60.6% (n = 63), highlighting the impact of this pain as very severe in 68.3% (n = 71) of the participants. Students with headache had more symptoms of stress (30.5 ± 7.6; p < 0.004) and fatigue (4.0 ± 1.4; p < 0.040). Conclusion An expressive number of headache cases was found, mainly in females, related to symptoms of stress and fatigue, impacting the quality of life of these university students.

Resumo Este estudo teve como objetivo estimar a força propulsora da braçada(FPB) em jovens nadadores do estilo livre e propor uma equação para estimar a força propulsora, considerando variáveis antropométricas e a maturação. Setenta e seis nadadores competitivos [meninos: n = 53; idade = 13,58 ± 1,79; meninas: n = 23; idade = 12,98 ± 1,79] participaram deste estudo. Foram avaliados: altura, massa magra, estatura sentada, comprimento da perna, envergadura, dobra cutânea do tríceps, área muscular do braço (AMB) e maturação. A força propulsiva da braçada foi medida pelo teste de nado atado. Uma regressão linear múltipla (modelo concorrente) foi usada para desenvolver a equação usando as variáveis AMB, envergadura e maturação. O método de Bland – Altman foi utilizado para comparar os valores encontrados entre FPB e força propulsiva estimada (FPE). Houve correlação significativa entre as variáveis FPB e AMB (R² = 0,12; p <0,01), envergadura (R² = 0,21; p <0,01) e maturação (R² = 0,20; p <0,01) para meninos, enquanto os valores das meninas foram: AMB (R² = 0,07; p = 0,20), envergadura (R² = 0,50; p <0,01) e maturação (R² = 0,44; p <0,01). Duas equações lineares foram estabelecidas para predizer a FPB em meninos e meninas. A análise de Bland-Altman mostrou concordância entre FPB e FPE. Em conclusão, a equação é uma ferramenta valiosa para monitorar o treinamento e ajudar a melhorar o desempenho do nadador.

Abstract This study aimed to estimate the propulsive force of the arm (PFA) in young freestyle swimmers and propose an equation to estimate propulsive force, considering anthropometric variables and maturity offset. Seventy-six competitive swimmers [boys: n= 53; age= 13.58 ± 1.79; girls: n= 23; age= 12.98 ± 1.79] participated in this study. Height, lean mass, sitting height, leg length, arm span, triceps skinfold, arm muscle area (AMA), and maturity offset were assessed. The propulsive force of the arm was measured by the tethered swim test. A multiple linear regression (concurrent model) was used to develop the equation using the variables AMA, arm span, and maturity offset. The Bland–Altman method was used to compare the values found between PFA and propulsive force–estimated (PFE). There was a significant correlation between the variables PFA and AMA (R²=0.12; p<0.01), arm span (R²=0.21; p<0.01), and maturity offset (R²=0.20; p<0.01) for boys, whilst in girls theses values were: AMA (R²=0.07;p=0.20), arm span (R²=0.50;p<0.01), and maturity offset (R²=0.44;p<0.01). Two linear equations were established to predict the PFA in boys and girls Bland-Altman analysis showed an agreement between PFA and PFE. In conclusion, the equation is a valuable tool to monitor training and help improve swimmer performance.

Abstract Process analyses foster opportunities for identifying losses during the production process and consequently, provide courses of action to enhance the process with operational parameters that are compatible with the targeted results. In this study, a thermochemical model was developed in order to monitor the performance of coke-based blast furnaces, focusing on tools for calculating and graphically displaying parameters that facilitate interpretation of the internal phenomena. To apply the model, a database was prepared based on operational simulations of blast furnaces. The input parameters for the model consisted of the properties and consumption of raw materials and the mass and thermal balances of the process. The thermochemical model is based on the calculation of the degree of reduction of the metallic burden in the preparation zone, defined as the omega factor. It was found that the omega factor varies significantly with the CO/CO2ratio and %H2of the top gas. The results obtained by applying this model were coherent, thus validating it as a predictive tool for assessing the sensitivity of the omega factor, which has a major effect on carbon consumption.