Abstract The objective of this study was to analyze the scientific literature in public oral health regarding calculation, presentation, and discussion of the effect size in observational studies. The scientific literature (2015 to 2019) was analyzed regarding: a) general information (journal and guidelines to authors, number of variables and outcomes), b) objective and consistency with sample calculation presentation; c) effect size (presentation, measure used and consistency with data discussion and conclusion). A total of 123 articles from 66 journals were analyzed. Most articles analyzed presented a single outcome (74%) and did not mention sample size calculation (69.9%). Among those who did, 70.3% showed consistency between sample calculation used and the objective. Only 3.3% of articles mentioned the term effect size and 24.4% did not consider that in the discussion of results, despite showing effect size calculation. Logistic regression was the most commonly used statistical methodology (98.4%) and Odds Ratio was the most commonly used effect size measure (94.3%), although it was not cited and discussed as an effect size measure in most studies (96.7%). It could be concluded that most researchers restrict the discussion of their results only to the statistical significance found in associations under study.

Resumo O objetivo deste estudo foi analisar a literatura científica da área de saúde bucal coletiva quanto ao cálculo, apresentação e discussão do tamanho do efeito em estudos observacionais. A literatura cientifica na área (2015 a 2019) foi analisada quanto: a) informações gerais (periódico e diretrizes aos autores, número de variáveis e desfechos), b) objetivo e coerência com o cálculo amostral apresentado; c) tamanho do efeito (apresentação, medida utilizada e coerência com a discussão dos dados e conclusão). Foram analisados 123 artigos, de 66 periódicos. A maioria dos artigos avaliados apresenta um único desfecho (74%) e não menciona a realização de cálculo amostral (69,9%). Dentre os que realizaram, para 70,3% havia coerência entre o cálculo amostral utilizado e o objetivo. Apenas 3,3% dos artigos mencionam o termo tamanho do efeito e 24,4% não o consideram na discussão dos resultados, apesar de terem calculado. A regressão logística foi a metodologia estatística mais utilizada (98,4%) e o Odds Ratio a medida de tamanho do efeito mais utilizada (94,3%), embora não tenha sido citada e discutida como uma medida de tamanho do efeito na maioria dos estudos (96,7%). Os pesquisadores, em sua maioria, restringiram a discussão dos resultados apenas à significância estatística encontrada nas associações testadas.

Resumo O objetivo foi investigar a prevalência da síndrome de burnout (SB) em profissionais de nível superior atuantes na saúde indígena no Brasil e fatores associados. Trata-se de um estudo observacional, transversal e analítico. O questionário foi aplicado (perfil e MBI-HSS) a 513 profissionais. A presença da SB foi identificada em 65% dos profissionais. Foi verificada maior chance de exaustão emocional entre os profissionais mais novos, com mais tempo de atuação na saúde indígena, em função assistencial e com menor nível de tranquilidade ao trabalhar durante a pandemia. Mais chance de apresentar baixa realização pessoal no trabalho foi observada entre os profissionais mais velhos, com menos tempo de atuação na saúde indígena, que estavam em atendimento clínico durante a pandemia e que relataram menor nível de tranquilidade ao trabalhar durante a pandemia. Maior chance de despersonificação em profissionais casados, em atendimento clínico durante a pandemia e com menor nível de tranquilidade ao trabalhar durante a pandemia. O estudo contribui com uma importante avaliação da existência de preditores da SB nos profissionais atuantes na saúde indígena.

Abstract The aim of this study was to investigate the prevalence of burnout syndrome in higher education health professionals working in indigenous health in Brazil, and to identify associated factors. This is an observational, analytical, and cross-sectional study. Data collection was based on the application of a questionnaire (personal profile and MBI-HSS) and included 513 professionals. The prevalence of burnout was 65%. Greater likelihood of emotional exhaustion was observed among younger professionals, who had worked in indigenous health for longer time, in the care function and with lower level of tranquility when working during the pandemic. Lower likelihood of having low personal accomplishment at work was observed among older professionals, professionals who had worked in indigenous health for shorter time, who worked in clinical care during the pandemic and those with lower level of tranquility when working during the pandemic. Greater likelihood of depersonalization was found among married professionals, who worked in clinical care during the pandemic and those with lower level of tranquility when working during the pandemic. This study contributes with an important assessment of the existence of BS predictors in health professionals working in indigenous health.

Resumo O objetivo foi investigar a prevalência da síndrome de burnout (SB) em profissionais de nível superior atuantes na saúde indígena no Brasil e fatores associados. Trata-se de um estudo observacional, transversal e analítico. O questionário foi aplicado (perfil e MBI-HSS) a 513 profissionais. A presença da SB foi identificada em 65% dos profissionais. Foi verificada maior chance de exaustão emocional entre os profissionais mais novos, com mais tempo de atuação na saúde indígena, em função assistencial e com menor nível de tranquilidade ao trabalhar durante a pandemia. Mais chance de apresentar baixa realização pessoal no trabalho foi observada entre os profissionais mais velhos, com menos tempo de atuação na saúde indígena, que estavam em atendimento clínico durante a pandemia e que relataram menor nível de tranquilidade ao trabalhar durante a pandemia. Maior chance de despersonificação em profissionais casados, em atendimento clínico durante a pandemia e com menor nível de tranquilidade ao trabalhar durante a pandemia. O estudo contribui com uma importante avaliação da existência de preditores da SB nos profissionais atuantes na saúde indígena.

Abstract The aim of this study was to investigate the prevalence of burnout syndrome in higher education health professionals working in indigenous health in Brazil, and to identify associated factors. This is an observational, analytical, and cross-sectional study. Data collection was based on the application of a questionnaire (personal profile and MBI-HSS) and included 513 professionals. The prevalence of burnout was 65%. Greater likelihood of emotional exhaustion was observed among younger professionals, who had worked in indigenous health for longer time, in the care function and with lower level of tranquility when working during the pandemic. Lower likelihood of having low personal accomplishment at work was observed among older professionals, professionals who had worked in indigenous health for shorter time, who worked in clinical care during the pandemic and those with lower level of tranquility when working during the pandemic. Greater likelihood of depersonalization was found among married professionals, who worked in clinical care during the pandemic and those with lower level of tranquility when working during the pandemic. This study contributes with an important assessment of the existence of BS predictors in health professionals working in indigenous health.

Resumo O objetivo deste estudo foi analisar a literatura científica da área de saúde bucal coletiva quanto ao cálculo, apresentação e discussão do tamanho do efeito em estudos observacionais. A literatura cientifica na área (2015 a 2019) foi analisada quanto: a) informações gerais (periódico e diretrizes aos autores, número de variáveis e desfechos), b) objetivo e coerência com o cálculo amostral apresentado; c) tamanho do efeito (apresentação, medida utilizada e coerência com a discussão dos dados e conclusão). Foram analisados 123 artigos, de 66 periódicos. A maioria dos artigos avaliados apresenta um único desfecho (74%) e não menciona a realização de cálculo amostral (69,9%). Dentre os que realizaram, para 70,3% havia coerência entre o cálculo amostral utilizado e o objetivo. Apenas 3,3% dos artigos mencionam o termo tamanho do efeito e 24,4% não o consideram na discussão dos resultados, apesar de terem calculado. A regressão logística foi a metodologia estatística mais utilizada (98,4%) e o Odds Ratio a medida de tamanho do efeito mais utilizada (94,3%), embora não tenha sido citada e discutida como uma medida de tamanho do efeito na maioria dos estudos (96,7%). Os pesquisadores, em sua maioria, restringiram a discussão dos resultados apenas à significância estatística encontrada nas associações testadas.

Abstract The objective of this study was to analyze the scientific literature in public oral health regarding calculation, presentation, and discussion of the effect size in observational studies. The scientific literature (2015 to 2019) was analyzed regarding: a) general information (journal and guidelines to authors, number of variables and outcomes), b) objective and consistency with sample calculation presentation; c) effect size (presentation, measure used and consistency with data discussion and conclusion). A total of 123 articles from 66 journals were analyzed. Most articles analyzed presented a single outcome (74%) and did not mention sample size calculation (69.9%). Among those who did, 70.3% showed consistency between sample calculation used and the objective. Only 3.3% of articles mentioned the term effect size and 24.4% did not consider that in the discussion of results, despite showing effect size calculation. Logistic regression was the most commonly used statistical methodology (98.4%) and Odds Ratio was the most commonly used effect size measure (94.3%), although it was not cited and discussed as an effect size measure in most studies (96.7%). It could be concluded that most researchers restrict the discussion of their results only to the statistical significance found in associations under study.

RESUMO Objetivos: compreender o significado atribuído pelas mulheres ao diagnóstico de sífilis e sífilis congênita, ao tratamento e acompanhamento ambulatorial da criança. Métodos: estudo qualitativo conduzido com 30 mães de crianças com sífilis congênita, por meio de entrevistas semiestruturadas, audiogravadas e submetidas a Análise Temática Indutiva. Adotou-se, por referencial teórico, o Interacionismo Simbólico. Resultados: dois temas emergiram e revelaram que o diagnóstico materno foi permeado por choque, culpa e medo da exclusão social, além de frustração ante o insucesso em evitar a transmissão vertical. Ainda, os procedimentos clínicos dolorosos para tratamento da criança potencializaram a culpa materna, e o processo simbólico de ressignificação da doença/tratamento aconteceu com a cura da criança. Considerações Finais: a compreensão dos aspectos intersubjetivos envolvidos nessa experiência instrumentaliza o enfermeiro para repensar sua prática assistencial e contribui para seu maior protagonismo no contexto da sífilis.

ABSTRACT Objectives: to understand the meanings attributed by women to the diagnosis and treatment of syphilis and congenital syphilis, and to outpatient follow-up of their children. Methods: this is a qualitative study conducted with 30 mothers of children with congenital syphilis using audio-recorded semi-structured interviews, which were submitted to inductive thematic analysis. Symbolic interactionism was the theoretical framework considered in this study. Results: two themes were identified, showing the maternal diagnosis involved shock, guilt, and fear of social exclusion, in addition to frustration due to failure to prevent vertical transmission. Moreover, the painful clinical procedures for the child’s treatment enhanced maternal guilt, and the symbolic process of re-signification of the disease/treatment took place with the child’s healing. Final Considerations: understanding the intersubjective aspects involved in this experience helps nurses rethink their care practice and contributes to their critical role in the context of syphilis.

RESUMEN Objetivos: comprender el significado atribuido por las mujeres al diagnóstico de sífilis y sífilis congénita, al tratamiento y seguimiento ambulatorio del niño. Métodos: estudio cualitativo realizado con 30 madres de niños con sífilis congénita mediante entrevistas semiestructuradas, grabadas en audio y sometidas a Análisis Temático Inductivo. Se adoptó como referencial teórico el Interaccionismo Simbólico. Resultados: surgieron dos temas revelando que el diagnóstico materno fue teñido por shock, culpa y miedo a la exclusión social, además de frustración frente al fracaso que no permitió evitar la transmisión vertical. También los procedimientos clínicos dolorosos para el tratamiento de los niños potenciaron la culpa maternal, y el proceso simbólico de resignificación de la enfermedad/tratamiento se dio con la cura del niño. Consideraciones Finales: la comprensión de los aspectos intersubjetivos involucrados en esta experiencia instrumentan al enfermero para reconsiderar su práctica asistencial y contribuye a un mayor protagonismo en el contexto de la sífilis.

■ Abstract Introduction: The branchial arches are the embryological precursors of the face, neck, and pharynx. Branchial arch anomalies are the second most common congenital head and neck lesions in children. Among these anomalies are branchial arch cysts (BCC), which arise due to incorrect obliteration of the branchial slits, still in the embryonic period. BCCs may be asymptomatic, only noticed incidentally, and not manifest until adulthood. Results: Anomalies of the second branchial arch should be considered as one of the possible differential diagnoses of neck masses, especially those that manifest as a bulge in the lateral region of the neck. BCCs are epithelial lining formations without external openings. After diagnosis, treatment is surgical, usually through a transverse cervical incision and careful dissection of the structures, with the aim of extirpating the entire lesion. Conclusion: The method described of excision of the lesion through a transverse incision in the cervical region, tissue dissection in planes, and resection of the cystic mass is an option for the treatment of this deformity, with adequate aesthetic results and good reproducibility.

■ RESUMO Introdução: Os arcos branquiais são os precursores embriológicos da face, pescoço e faringe. As anomalias dos arcos branquiais são a segunda lesão congênita mais comum de cabeça e pescoço em crianças. Entre essas anomalias, estão os cistos de arcos branquiais (BCC), que surgem devido a uma incorreta obliteração das fendas branquiais, ainda no período embrionário. Os BCC podem ser assintomáticos, apenas percebidos incidentalmente, e não se manifestar até a idade adulta. Resultados: Anomalias do segundo arco branquial devem ser consideradas como um dos possíveis diagnósticos diferenciais de massas cervicais, especialmente as que se manifestam como um abaulamento em região lateral do pescoço. Os BCC são formações de revestimento epitelial, sem aberturas externas. Após seu diagnóstico, o tratamento é cirúrgico, usualmente por meio de uma incisão cervical transversa e cuidadosa dissecação das estruturas, com o objetivo de extirpar toda a lesão. Conclusão: O método descrito, de excisão da lesão, por meio de incisão transversa em região cervical, dissecção tecidual por planos e ressecção de massa cística, é uma opção para o tratamento dessa deformidade, com adequado resultado estético e boa reprodutibilidade.

Abstract Background The Psychosocial Care Center was created as part of the psychiatric reform process. Objective The objective of this study was to evaluate the influence of the assemblies held at the CAPS II Psychosocial Care Center of Boa Vista RR on the humanization of mental health. Method This qualitative study evaluated 10 individuals from the 22 who met the inclusion criteria. The study used a content analysis methodology applying an interview script containing 7 open questions regarding the effectiveness of humanization in the context of the assemblies. Results The relationship between patient, professional and manager improved after the assemblies were held. Regarding the work undertaken by the management, participants highlighted the organization and humanization. The work of the professional team was considered excellent by most of the interviewees and the CAPS acts in a humanized way when assisting people in psychological distress. Conclusion The assemblies influenced the humanization of mental health in the face of behavioural changes through the relationship established during the aforementioned meetings. This reflected the logic of psychiatric reform and the substitution of hospital-centered practices with the re-socialization of individuals and families.

Resumo Introdução Os Centro de Atenção Psicossocial (CAPS) foram criados como parte do processo de reforma psiquiátrica. Objetivo O objetivo deste estudo foi avaliar a influência das assembleias realizadas no Centro de Atenção Psicossocial CAPS II de Boa Vista (RR) na humanização em saúde mental. Método Esta pesquisa qualitativa avaliou 10 indivíduos dentre os 22 que preencheram os critérios de inclusão. O estudo utilizou a técnica de análise de conteúdo e um roteiro de entrevista contendo 07 perguntas abertas sobre a efetivação da humanização em meio à realização de assembleias. Resultados A relação paciente, profissional e gestor melhorou após a realização das assembleias. Quanto ao trabalho desenvolvido pela gestão, os participantes atribuíram organização e humanização. O trabalho da equipe profissional foi considerado excelente pela maioria dos entrevistados, e o CAPS atua de forma humanizada no atendimento à pessoa em sofrimento psíquico. Conclusão As assembleias influenciaram a humanização em saúde mental em face das mudanças de comportamento e relacionamento propiciadas pelo vínculo que se fez presente durante as mencionadas reuniões, tangenciando assim para lógica da reforma psiquiátrica e substituição de práticas hospitalocêntricas com vistas na ressocialização dos indivíduos e familiares.

Abstract Objective: To present an updated and evidence-based guideline for the use of dual-energy x-ray absorptiometry (DXA) to assess body composition in clinical practice. Materials and methods: This Official Position was developed by the Scientific Committee of the Brazilian Association of Bone Assessment and Metabolism ( Associação Brasileira de Avaliação Óssea e Osteometabolismo , ABRASSO) and experts in the field who were invited to contribute to the preparation of this document. The authors searched current databases for relevant publications in the area of body composition assessment. In this second part of the Official Position, the authors discuss the interpretation and reporting of body composition parameters assessed by DXA and the use of DXA for body composition evaluation in special situations, including evaluation of children, persons with HIV, and animals. Conclusion: This document offers recommendations for the use of DXA in body composition evaluation, including indications, interpretation, and applications, to serve as a guiding tool in clinical practice and research for health care professionals in Brazil.

Abstract The chemically complex essential oils of Baccharis species are associated with several biological activities, such as antimicrobial and antiulcerous properties. However, few studies have investigated Baccharis erioclada DC. Therefore, in this study, we aimed to characterize the essential oil of B. erioclada and evaluate its antioxidant, antimicrobial, and hemolytic potential. The essential oil was extracted by hydrodistillation using a Clevenger apparatus and analyzed via gas chromatography-mass spectrometry (GC-MS). Phosphomolybdenum complex formation, reducing antioxidant power, and thiobarbituric acid reactive substances (TBARS) methods were used to determine antioxidant potential. To evaluate the essential oil’s antimicrobial activity, minimum inhibitory concentrations (MIC) in Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa, and Candida albicans were calculated. Hemolytic activity was determined in sheep red blood cells. Thirty-one compounds were identified via GC-MS analysis, representing 81.60% of the total essential oil. These compounds included: turmerone (27.97%), fokienol (13.47%), ledol (9.78%), and santalol (5.35%). The class of compounds identified was the oxygenated sesquiterpenes (62.52%). Antioxidant activity was confirmed via phosphomolybdenum complex formation and TBARS methods. Moderate antimicrobial activity and low hemolysis rates were displayed at concentrations of 250 and 500 μg/mL.

Abstract Bjerkandera adusta, a globally distributed fungus, is commonly used in the nutritional practices of the East Asian population. In this study, we evaluated the nutritional composition of the lyophilized mycelium of B. adusta as well as the phenolic composition and antioxidant activity of its extracts. The mycelium exhibited moisture (7.97 %), ash (3.27 %), and fiber (5.31 %) content values similar to the established values reported in the available literature. In addition, a high protein (9.32 %) and carbohydrate (63.45 %) content was shown, with a low lipid (1.36 %) content. The energy value per 100 g sample of mycelium was 1445.85 kJ. The results obtained indicated a statistically significant variation (p < 0.05) in the phenolic composition (81.84-110.96 mg gallic acid equivalents (GAE) per g of extract), free radical 1,1-diphenyl-2-picrylhydrazyl (DPPH) scavenging activity (IC50 29.05-340.46 µg·mL-1), phosphomolybdenum antioxidant content (34.89-55.64 %), reduction of ferricyanide ion (66.55-69.4 %), and thiobarbituric acid reactive substance (TBARS) values (44.66-133.03 %). These results are unprecedented for this species and emphasize its nutraceutical potential.

Resumo Introdução Ações educativas são fundamentais para a produção do cuidado e fazem parte das atividades dos agentes comunitários de saúde (ACS). Objetivo Avaliar o conhecimento dos ACS sobre saúde bucal e fatores relacionados. Método Estudo transversal e quantitativo, com 481 ACS vinculados aos municípios da X Gerência de Saúde de Pernambuco. A coleta foi realizada em 2017 nas reuniões mensais, com questionário validado e autoadministrado. As associações foram testadas por regressão logística múltipla, estimando-se os odds ratio brutos com os intervalos de confiança de 95%. Resultados Participaram 72,9% (351) dos ACS, sendo a maioria do sexo feminino, com até 40 anos, ensino médio completo, renda de até 1 salário mínimo e com mais de 10 anos de trabalho. Observou-se que 23,6% afirmaram que a equipe realizava reuniões frequentes e 12% disseram que os dentistas realizavam capacitação. Para 68,1%, a experiência de vida era a fonte do conhecimento. Os ACS do sexo feminino e que não nominaram a fonte de seu conhecimento tinham 1,90 (IC95%: 1,10-3,28) e 3,59 (IC95%: 1,46-8,79) vezes mais chance, respectivamente, de apresentar menor conhecimento (p < 0,05). Conclusão O conhecimento foi satisfatório e influenciado negativamente pelo sexo e pela ausência de relato da fonte de aquisição de informações sobre saúde bucal.

Abstract Background Educational actions are fundamental to produce care, and are part of the activities of community-based health workers (CHWs). Objective Evaluate the knowledge of CHWs about oral health (OH) and associated factors. Method This is a cross-sectional, quantitative study. All 481 CHWs linked to the municipalities belonging the 10th Health Management Section of the state of Pernambuco, Brazil, were invited to participate in the study. Data collection was performed in 2017 during the monthly sectional meetings by means of a validated, self-administered questionnaire. The associations were tested by multiple logistic regression, estimating the crude odds ratio with 95% confidence intervals. Results 72.9% (351) of the CHWs participated in the study. They were mostly women, aged ≤40 years, with complete high school, monthly income of up to one Brazilian minimum wage, and with more than 10 years of work experience. 23.6% of the CHWs stated that the team frequently attended meetings, and 12.0% of them said that the dentists underwent training. As for the source of knowledge acquisition, 68.1% answered that it accrued from life experience. Female CHWs and those who did not mention the source of their knowledge about OH were 1.90 (95% CI: 1.10-3.28) and 3.59 (95% CI: 1.46-8.79) times more likely, respectively, to present a lower OH score (p<0.05). Conclusion The knowledge about OH of CHWs was satisfactory, but negatively influenced by gender and absence of report on the source of acquisition of OH information.

RESUMEN La turba es un material orgánico que se ha utilizado ampliamente como adsorbente eficiente y de bajo costo. Dado que muchos estudios tienden a centrarse en las turbas templadas, hay una falta de conocimiento sobre el mecanismo de adsorción de las turbas tropicales. Este trabajo investiga el uso de dos turbas brasileñas (Cravinhos - C y Luis Antonio - LA) de la cuenca del río Mogi-Guacu para la adsorción de plomo (Pb), zinc (Zn) y cadmio (Cd), con el fin de contribuir al uso de materiales locales y de fácil acceso para remediar sitios contaminados. Las turbas adsorbieron un alto porcentaje de cationes, especialmente cationes Pb (100,0-46,3%), mostrando la turba comercial C una mayor adsorción que la turba LA. La orden de eliminación fue Pb2+ > Cd2+ ≥ Zn2+ para C y Pb2+ > Zn2+ > Cd2+ para LA. Los datos de equilibrio por lotes para turbas y para todos los metales se ajustaron mejor a la isoterma de Langmuir, con capacidades de adsorción (qm) para Pb, Zn y Cd de 37,3134, 29,0674 y 21,2890 mmol kg-1 en turba C y 21,7391, 14,2550 y 3,6460. mmol kg-1 en LA, respectivamente, valores comparables a los de otras turbas y biosorbentes. Las turbas estudiadas se consideran materiales adsorbentes eficientes, alternativos y de bajo costo para estos metales. La proximidad de las turberas a áreas con alto potencial de contaminación requiere el uso de materiales locales para reducir los costos de remediación.

ABSTRACT Peat is an organic material that has been widely used as an efficient and low-cost adsorbent. As many studies tend to focus on temperate peats, there is a lack of knowledge about the adsorption mechanism of tropical peats. This paper investigates the use of two Brazilian peats (Cravinhos - C and Luis Antônio - LA) from the Mogi-Guaçu river basin for the adsorption of lead (Pb), zinc (Zn), and cadmium (Cd), in order to contribute to the use of local and easy access materials to remediate contaminated sites. The peats adsorbed a high percentage of cations, especially Pb cations (100.0-46.3%), with commercial peat C showing higher adsorption than peat LA. The removal order was Pb2+ > Cd2+ ≥ Zn2+ for C and Pb2+ > Zn2+ > Cd2+ for LA. The batch data for both peats and for all metals were better fit by the Langmuir isotherm, with adsorption capacities (q m ) for Pb, Zn, and Cd of 37.3134, 29.0674 and 21.2890 mmol kg-1 in peat C and 21.7391, 14.2550 and 3.6460 mmol kg-1 in LA, respectively, values comparable to those of other peats and biosorbents. The studied peats are considered efficient, alternative and low-cost adsorptive materials for these metals. The proximity of peatlands to areas with high potential for contamination necessitates the use of local materials to reduce remediation costs.

Abstract Background: In the past 20 years, hematopoietic stem cell transplantation (HSCT) has been investigated as treatment for systemic sclerosis (SSc). The goal of HSCT is to eradicate the autoreactive immune system, which is replaced by a new immune repertoire with long-lasting regulation and tolerance to autoantigens. Here, we describe the clinical outcomes of severe and refractory SSc patients that underwent HSCT at a single Brazilian center. Patients and methods: This is a longitudinal and retrospective study, including 70 adult SSc patients, with an established diagnosis of SSc, and who underwent autologous HSCT from 2009 to 2016. The procedure included harvesting and cryopreservation of autologous hematopoietic progenitor cells, followed by administration of an immunoablative regimen and subsequent infusion of the previously collected cells. Patients were evaluated immediately before transplantation, at 6 months and then yearly until at least 5-years of post-transplantation follow-up. At each evaluation time point, patients underwent clinical examination, including modified Rodnan's skin score (mRSS) assessment, echocardiography, high-resolution computed tomography of the lungs and pulmonary function. Results: Median (range) age was 35.9 (19–59), with 57 (81.4%) female and median (range) non-Raynaud's disease duration of 2 (1–7) years. Before transplantation, 96% of the patients had diffuse skin involvement, 84.2%, interstitial lung disease and 67%, positive anti-topoisomerase I antibodies. Skin involvement significantly improved, with a decline in mRSS at all post-transplantation time points until at least 5-years of follow-up. When patients with pre-HSCT interstitial lung disease were analyzed, there was an improvement in pulmonary function (forced vital capacity and diffusing capacity of lung for carbon monoxide) over the 5-year follow-up. Overall survival was 81% and progression-free survival was 70.5% at 8-years after HSCT. Three patients died due to transplant-related toxicity, 9 patients died over follow-up due to disease reactivation and one patient died due to thrombotic thrombocytopenic purpura. Conclusions: Autologous hematopoietic progenitor cell transplantation improves skin and interstitial lung involvement. These results are in line with the international experience and support HSCT as a viable therapeutic alternative for patients with severe and progressive systemic sclerosis.

RESUMO Objetivo Avaliar se a área de graduação influencia nos aspectos de saúde bucal avaliados. Métodos Estudo transversal com amostra probabilística de 681 estudantes do 2º período de uma Instituição de Ensino Superior foi alocada nos grupos Saúde (S; n=347) e Não Saúde (NS; n=334) e respondeu questionário englobando perfil sociodemográfico e aspectos de saúde bucal. Os dados foram analisados pelos Testes Qui-quadrado/Exato de Fisher (α=5%). Resultados A maioria dos estudantes era de sexo feminino (S=70,0%; NS=56,9%; p=0,0004), solteiro (S=82,7%; NS=76,0%; p=0,0429) e não trabalha (S=30,5%; NS=37,7%; p=0,0482). Os grupos diferiram quanto a ter recebido orientações sobre saúde bucal pela mídia (S=19,9%; NS=13,8%; p=0,0333) ou por outros profissionais da saúde (S=25,6%; NS=13,2%; p<0,0001). Quanto aos motivos para a última consulta odontológica, prevaleceu para o grupo S “tratamento” (42,9%) e “dor” (6,9%) enquanto para o grupo NS “revisão, prevenção ou check-up” (41,9%) e “extração” (8,1%) (p=0,0169). O grupo S mostrou-se mais satisfeito em relação à saúde bucal, com menor frequência de relatos sobre autopercepção de mau hálito (S=30,3%; NS=38,3%; p=0,0483). Não houve associação da autopercepção e impactos em saúde bucal (p>0,05). Conclusão Os grupos diferiram quanto à fonte de informações sobre saúde bucal, razão da busca e tipo de tratamento, e autopercepção de mau hálito, com o grupo Saúde referindo maior satisfação com sua saúde bucal.

ABSTRACT Objetive To evaluate whether the area of study of undergraduate students influences oral health knowledge, attitudes and practices, in addition to the use of dental services, self-reported oral morbidity, self-perception and impacts of oral health. Methods A cross-sectional study was performed, with a probabilistic sample of 681 students from the second semester of a Higher Education Institution, who were allocated into Health (H; n = 347) and Non-Health (NH; n = 334) groups, and answered a questionnaire encompassing their sociodemographic profile and aspects of oral health. Data were analyzed by Fisher’s Chi-Square/Exact Test (α = 5%). Results The majority of students were female (H = 70.0%, NH = 56.9%, p = 0.0004), single (H = 82.7%, NH = 76.0%, p = 0.0429) and did not work (H = 30.5%, NH = 37.7%, p = 0.0482). The groups differed in terms of receiving oral health guidelines from the media (H = 19.9%, NH = 13.8%, p = 0.0333) or from other health professionals (H = 25.6%, NH = 13.2%, p <0.0001). Regarding the reasons for their most recent dental appointment, in the Health group “treatment” (42.9%) and “pain” (6.9%) prevailed, while for the Non-Health group “review, prevention or check-up” (41, 9%) and “extraction” (8.1%) (p = 0.0169) were the most prevalent. The Health group was more satisfied with their oral health, with less frequent reports of a self-perception of bad breath (H = 30.3%, NH = 38.3%, p = 0.0483). There was no association between self-perception and impacts on oral health (p> 0.05). Conclusions The groups differed regarding the source of information on oral health, the reason for seeking and type of treatment, and the self-perception of bad breath, with the Health group reporting greater satisfaction with their oral health.

Objetivo: construir e validar um vídeo educativo sobre o manejo da parada cardiorrespiratória pediátrica por insuficiência respiratória. Método: estudo metodológico desenvolvido em três etapas: elaboração e validação de um caso clínico; produção; e validação de vídeo educativo. Para construção do vídeo educativo foi utilizado o referencial metodológico de Fleming, Reynolds e Wallace. Resultados: o caso clínico foi validado por 10 juízes expertises e enfermeiros de diferentes regiões do Brasil, por meio de formulário on-line, com uma rodada de avaliação e cálculo do Índice de Validação de Conteúdo. O vídeo educativo foi validado por três juízes expertises e 25 acadêmicos de Enfermagem em uma rodada de avaliação e contém seis cenas e duração de nove minutos e cinquenta e seis segundos. Tanto o caso clínico quanto o vídeo educativo obteve-se para a maior parte dos itens, 80% ou mais de concordância. Conclusão: vídeo educativo mostrou-se válido quanto à aparência e ao conteúdo. Essa tecnologia educacional tem potencial para atender às demandas de alunos, nativos digitais, tanto quanto ao ensino do manejo da parada cardiorrespiratória pediátrica ocasionada por insuficiência respiratória.

Objective: to make and validate an educational video about the management of pediatric cardiopulmonary arrest caused by respiratory failure. Method: methodological study developed in three stages: preparation and validation of a clinical case; production; and validation of educational video. To build the educational video, the Fleming, Reynolds and Wallace methodological framework was used. Results: the clinical case was validated by ten expert referees, who worked as nurses in different regions in Brazil, by completing an online form, with one round of evaluation and calculation of the content validity index. The educational video was validated by three expert judges and 25 nursing students in an evaluation round and contains six scenes, with duration of nine minutes and 56 seconds. An agreement over 80% was reached for most of the items in both the clinical case and the educational video. Conclusion: the educational video proved valid regarding face and content. This educational technology has the potential to meet the demands of students, who are digital natives, related to teaching of management of pediatric cardiopulmonary arrest caused by respiratory failure.

Objetivo: construir y validar un video educativo sobre manejo del paro cardiorrespiratorio pediátrico por insuficiencia respiratoria. Método: estudio metodológico desarrollado en tres etapas: elaboración y validación de un caso clínico; producción; y validación de video educativo. Para la construcción del video educativo se utilizó el marco metodológico de Fleming, Reynolds y Wallace. Resultados: el caso clínico fue validado por 10 jurados expertos, enfermeros de diferentes regiones de Brasil, mediante formulario online, en una ronda de evaluación y calculándose Índice de Validación de Contenido. El video educativo fue validado por tres jueces expertos y 25 estudiantes de enfermería en una ronda de evaluación y contiene seis escenas, de nueve minutos cincuenta y seis segundos. Se obtuvo concordancia de 80% o superior para la mayoría de los ítems del caso clínico y del video educativo. Conclusión: el video educativo demostró validez en cuanto a apariencia y contenido. Esta tecnología educacional tiene potencial para satisfacer la demanda de alumnos nativos digitales en la enseñanza del manejo del paro cardiorrespiratorio pediátrico ocasionado por insuficiencia respiratoria.