Nano SbCl5.SiO2 as an eco-friendly and efficient nanocatalyst was applied for quinoxaline derivatives preparation with improved yield. In this protocol, α-diketones and 1,2-diamines were condensed in the presence of nanocatalyst at room temperature under solventless conditions. The method gave good yields of quinoxaline derivatives in short reaction times in comparison with earlier methods. Using nontoxic and inexpensive materials, simple work-up, short reaction times and high yields of the products are the advantages of this method.

O ácido Al(HSO4)3 sólido foi usado na acetalização de compostos carbonílicos à temperatura ambiente, sem solvente, levando aos produtos desejados em excelentes rendimentos. A disponibilidade e baixo custo deste reagente, aliados a processo simples e fácil torna o método atraente para a síntese orgânica.

Al(HSO4)3 as a solid acid was applied for acetalization of carbonyl compounds at room temperature and under solvent-free conditions with good to excellent yields. The cheapness and availability of this reagent with easy procedure and work-up make this method attractive for the organic synthesis.