Figure 1 - Effect of anti-TNF antibodies or L-NAME (iNOS inhibitor) treatment on NO production and macrophage cytotoxicity. BCG-activated macrophages were co-cultured with L929 cells in the presence of anti-TNF antibodies (20 g/ml) or L-NAME (2.5, 5.0 and 10 mM) and nitrite concentration and cytotoxicity were determined 48 h later. Values represent the mean SD for 5 individual mice. *Significant differences between groups (P<0.05) (Student t-test).