Fig. 1: increased B-cell infiltration in localized cutaneous leishmaniasis (LCL) lesions. Biopsies were taken from skin lesions of LCL and disseminated cutaneous leishmaniasis (DL) patients. Cellular subsets were identified by immunohistochemistry using anti-CD20 (B lymphocytes), anti-CD68 (macrophages), anti-CD3, anti-CD4, and anti-CD8 (T lymphocytes). Each point represents the number of positive cells in the lesion of a patient with LCL or DL lesions. Significance levels are indicated.