Evidence of the effect of dipyrone on the central nervous system as a determinant of delayed gastric emptying observed in rats after its administration. E.F. Collares and A.M. Vinagre. Brazilian Journal of Medical and Biological Research, 36 (10): 1375, 2003.
Figure 1. Gastric retention (%), reported as mean ± SEM, of a saline test meal determined 10 min after administration to rats by gavage. The animals (N = 5) received iv vehicle (0) or dipyrone (10, 20, 40 and 80 mg/kg) 60 min before the determination of gastric retention. *P < 0.01 for the comparisons indicated by the arrows (Tukey test).