E. Ono, A.M. Nunes dos Santos, R.C. de Menezes Succi, D.M. Machado, D.S.A. de Angelis, R. Salomão, E.G. Kallás and M.I. de Moraes-Pinto. Imbalance of naive and memory T lymphocytes with sustained high cellular activation during the first year of life from uninfected children born to HIV-1-infected mothers on HAART. Braz J Med Biol Res 2008; 41: 700-708.

Figure 1. CD4+ and CD8+ T cell subsets using CD45RA and CCR7 markers in HIV-exposed uninfected (ENI) and in control healthy (CT) neonates at birth (cord blood) and in infants at 12 months of age. A, CD4+ T cell subset in 45 HIV-exposed uninfected neonates and in 45 control healthy neonates. B, CD8+ T cell subset in 45 HIV-exposed uninfected neonates and in 45 control healthy neonates. C, CD4+ T cell subset at 12 months of age in 23 HIV-exposed uninfected infants and in 23 control healthy infants. D, CD8+ T cell subset at 12 months of age in 23 HIV-exposed uninfected infants and in 23 control healthy infants. Horizontal lines in box plots indicate the 25th, 50th, and 75th percentiles; top and bottom vertical lines mark extreme values and, when present, the small circles represent outlying values. The t-test was used for statistical analysis.