Long-term melatonin treatment reduces ovarian mass and enhances tissue antioxidant defenses during ovulation in the rat. L.G.A. Chuffa, J.P.A. Amorim, G.R. Teixeira, L.O. Mendes, B.A. Fioruci, P.F.F. Pinheiro, F.R.F. Seiva, E.L.B. Novelli, W. Mello Júnior, M. Martinez and F.E. Martinez. Braz J Med Biol Res 2011; 44: 217-223.

Figure 3. Influence of melatonin administration (100 µg·100 g body weight-1·day-1) on relative food intake for 60 days of rats receiving standard chow. Data are reported as means ± SEM for 10 animals per group. *P < 0.01 vs control group on days 10 to 60 of treatment (Student t-test). Day 0: Food consumption before the beginning of melatonin administration.