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Figure 3. A, Active internal diameters of tail arteries from Wistar rats (N = 4 animals) and spontaneously hypertensive rats (SHR, N = 5 animals) fixed at a volumetric flow rate of 2.5 mL/min. *P < 0.05 vs proximal portion; #P < 0.05 vs Wistar rats (two-way ANOVA followed by the Bonferroni post hoc test). B, Photomicrograph of transverse sections of proximal and distal tail artery from Wistar rats and SHR. Magnification: 10X. Inset panels in the proximal tail artery photomicrographs of Wistar and SHR are amplified images showing the endothelial (E), medium (M) and adventitial (A) layers of the artery.