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Figure 1. Fractional excretion of sodium (FE Na+) in rats submitted to sodium overload (CS and DOS) or without sodium overload (C and DO). Data are reported as means ± SEM. C = control; DO = diabetic offspring. *P < 0.05 compared to C; **P < 0.05 compared to CS (analysis of variance followed by the Bonferroni test). Reprinted, with permission, from Rocco (29).