Comparative proteomics analysis of chronic atrophic gastritis: changes of protein expression in chronic atrophic gastritis without Helicobacter pylori infection. Lin Zhang, Yanhong Hou, Kai Wu and Dan Li.
Figure 1. Detection and analysis of differentially expressed proteins in chronic atrophic gastritis (CAG). A, Representative 2-DE images of matched CAG and normal gastric mucosa tissue. The proteins expressed in CAG tissue were compared with those expressed in matched normal tissue. Fifteen spots were identified by mass spectrometry in 18 differentially expressed protein spots (Table 2). B, Magnified regions of the 2-DE gel of down-regulated PSME1 (left) and up-regulated RPS12 (right) in CAG tissue when compared with normal tissue. C, Analysis of the depicted peptide spectrum resulted in the identification of PSME1 (left) and RPS12 (right).