Comparative proteomics analysis of chronic atrophic gastritis: changes of protein expression in chronic atrophic gastritis without Helicobacter pylori infection. Lin Zhang, Yanhong Hou, Kai Wu and Dan Li.
Figure 3. Western blot analysis of PSME1 and RPS12. A, Down-regulation of PSME1 in chronic atrophic gastritis (CAG) (C) tissue. Western blot assays were performed to demonstrate the differential expression of the PSME1 protein between CAG and normal (N) gastric mucosa. The specific proteins were visualized with a chemiluminescent reagent. As a control for equal protein loading, blots were restained with antiactin antibody. Immunosignals were quantified by densitometry scanning. The relative quantification was calculated as the ratio of PSME1 to actin as shown in the bar graph. B, Up-regulation of RPS12 in CAG (C) tissue compared to normal (N) mucosa. The same experimental process was performed. The relative quantification was calculated as the ratio of RPS12 to actin as also shown in the bar graph.