Patients undergoing pulmonary rehabilitation (n: 46) | Healthy control subjects (n: 32) | p value | |
---|---|---|---|
Age (years) | 60.8 ± 10.2 | 58.5 ± 8.9 | 0.15 |
Gender (male,%) | 28(61%) | 13(41%) | |
Body mass index (kg/m2) | 28.2 ± 8.4 | 27.9 ± 7.2 | 0.67 |
Heart rate (beats/min) | 78 ± 12 | 80 ± 10 | 0.77 |
GOLD classes 2/3/4, n | 22/18/7 | ||
RV end-diastolic basal diameter (mm) | 38.1 ± 4.1 | 27.6 ± 3.5 | < 0.001 |
RV end-diastolic longitudinal diameter (mm) | 74.2 ± 9.4 | 60.4 ± 6.4 | < 0.001 |
RV anterior wall thickness (mm) | 4.35 ± 0.21 | 4.19 ± 0.31 | 0.82 |
RA end-systolic area (mm2) | 17.2 ± 2.9 | 12.9 ± 1.8 | < 0.001 |
sPAB (mmHg) | 46.7 ± 15.4 | 24.8 ± 10.5 | < 0.001 |
TAPSE (mm) | 16.6 ± 2.6 | 20.4 ± 3.1 | < 0.001 |
Tissue Doppler MPI | 0.58 ± 0.08 | 0.35 ± 0.05 | < 0.001 |
RV ejection fraction (%) | 54.8 ± 4.9 | 56.3 ± 5.5 | 0.41 |
LV ejection fraction (%) | 57.7 ± 5.5 | 59.4 ± 4.4 | 0.34 |
RV-TDI s' | 12.9 ± 2.93 | 13.6 ± 3.06 | 0.38 |
RV free wall longitudinal strain (%) | 18.1 ± 3.4 | 27.9 ± 3.6 | < 0.001 |
RV global longitudinal strain (%) | 20.4 ± 2.4 | 26.8 ± 3.2 | < 0.001 |
Before pulmonary rehabilitation (n:46) | 3 months after pulmonary rehabilitation (n:46) | p value | |
---|---|---|---|
RV end-diastolic basal diameter (mm) | 38.1 ± 4.1 | 37.7 ± 4.0 | 0.23 |
RV end-diastolic longitudinal diameter (mm) | 74.2 ± 9.4 | 73.5 ± 9.3 | 0.69 |
RV anterior wall thickness (mm) | 4.35 ± 0.21 | 4.22 ± 0.26 | 0.87 |
RA end-systolic area (mm2) | 17.2 ± 2.9 | 16.9 ± 2.4 | 0.18 |
sPAB (mmHg) | 46.7 ± 15.4 | 43.2 ± 16.3 | 0.03 |
TAPSE (mm) | 16.6 ± 2.6 | 17.2 ± 3.1 | 0.09 |
Tissue Doppler MPI | 0.58 ± 0.08 | 0.55 ± 0.07 | 0.09 |
RV ejection fraction (%) | 54.8 ± 4.9 | 55.2 ± 5.0 | 0.72 |
LV ejection fraction (%) | 57.7 ± 5.5 | 57.4 ± 5.2 | 0.57 |
RV-TDI s' | 12.9 ± 2.93 | 11.8 ± 3.06 | 0.47 |
RV free wall longitudinal strain (%) | 18.1 ± 3.4 | 22.9 ± 3.7 | < 0.001 |
RV global longitudinal strain (%) | 20.4 ± 2.4 | 21.9 ± 2.9 | < 0.001 |
Six-minute walk test (m) | 326 ± 42.2 | 355 ± 57.1 | < 0.001 |
mMRC score | 1.8 ± 0.8 | 1.7 ± 0.7 | 0.14 |
BODE index | 3.0 ± 2.1 | 2.8 ± 1.9 | 0.04 |