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Changes in the pre- and postoperative parameters in metabolic syndrome patients submitted to Roux-en-Y gastric bypass

BACKGROUND: Overweight and obesity affects approximately 1.7 billion people, with increase in morbid obesity of 80% for women and 400% for men, since 1970. Metabolic syndrome is a complex disorder associated with insulin resistance and abdominal obesity, causing changes in glucose metabolism in various tissues and hyperinsulinemia. AIM: To verify changes in the pre and post-operative parameters in morbidly obese patients with metabolic syndrome who underwent to Roux-en-Y gastrointestinal bypass. METHOD: Seventy four patients with obesity with metabolic syndrome submitted to gastrointestinal bypass Roux-en-Y were included. All of them had measured waist-hip ratio, blood pressure, total cholesterol, HDL, LDL, triglycerides and fasting glucose pre-operatively and at the first and fourth month post-operatively. RESULTS: In the first post-operative month, happened a weight reduction of 7.96%, BMI of 8%, waist-hip ratio of 1.35%, total cholesterol of 17.95%, HDL of 14.5%, LDL of 15.31%, TAG's of 30.29% and 9.75% of glucose; on the fourth month was observed a weight reduction of 14.94%, BMI of 20.08%, waist-hip ratio of 5.96%, total cholesterol of 21.27%, HDL of 3.53%, LDL of 23.72%, TAG's of 29.6% and 10.34% of glucose. CONCLUSION: All the parameters evaluated in this study had a statistic significant improvement, with the exception of HDL-cholesterol.

Metabolic syndrome; Obesity; Gastrointestinal Roux-en-Y bypass


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