Bullous pemphigoid and neurological disease: statistics from a
               dermatology service

Tarazona, Monica Jidid Mateus; Mota, Amanda Nascimento Cavalleiro de Macedo; Gripp, Alexandre Carlos; Unterstell, Natasha; Bressan, Aline Lopes

doi:10.1590/abd1806-4841.20153334

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Communication • An. bras. dermatol. 90 (2) • Mar-Apr 2015 • https://doi.org/10.1590/abd1806-4841.20153334 copy

Bullous pemphigoid and neurological disease: statistics from a dermatology service^* * Work performed at Pedro Ernesto University Hospital - Rio de Janeiro State University (HUPE-UERJ) - Rio de Janeiro (RJ), Brazil.

Authorship SCIMAGO INSTITUTIONS RANKINGS

Bullous pemphigoid (BP) is an autoimmune, acquired, cutaneous disease caused by the production of autoantibodies against hemidesmosomes' components in the basement membrane. The estimated incidence in Europe ranges from 7 to 43 cases per million inhabitants per year. Several studies have reported an association between BP and neurological disorders (ND). Our cohort of Bullous pemphigoid and ND is the first in Brazil and showed a significantly high prevalence of neurological and/or psychiatric diseases, especially cerebrovascular accident (CVA) and dementia, in agreement with the prevalence reported in several studies published in the medical literature in recent years.

Dementia; Pemphigoid, bullous; Stroke

Patient No	Gender	Age at BP diagnosis (years)	Presence of ND	Type of ND
1	M	71	No	NA
2	F	55	Yes	CVA
3	F	77	NIA	NA
4	F	75	NIA	NA
5	F	73	No	NA
6	F	88	No	NA
7	F	87	Yes	CVA
8	M	88	Yes	CVA
9	F	83	Yes	Epilepsy
10	F	73	No	NA
11	M	50	NIA	NA
12	F	71	No	NA
13	M	38	Yes	Panic syndrome
14	F	85	No	NA
15	F	77	Yes	Dementia
16	M	88	NIA	NA
17	F	47	No	NA
18	F	75	NIA	NA
19	F	86	Yes	Depression
20	F	91	Yes	Dementia
21	F	82	NIA	NA
22	F	63	No	NA
23	M	92	No	NA
24	F	64	NIA	NA
25	M	70	Yes	CVA

Sociedade Brasileira de Dermatologia Av. Rio Branco, 39 18. and., 20090-003 Rio de Janeiro RJ, Tel./Fax: +55 21 2253-6747 - Rio de Janeiro - RJ - Brazil
E-mail: revista@sbd.org.br

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[1] MAILING ADDRESS: Monica Jidid Mateus Tarazona, Boulevard 28 de setembro, 77 Vila Isabel, 20551-030 - Rio de Janeiro - RJ Brazil. E-mail: monicajmateus@hotmail.com

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Bullous pemphigoid and neurological disease: statistics from a dermatology service* * Work performed at Pedro Ernesto University Hospital - Rio de Janeiro State University (HUPE-UERJ) - Rio de Janeiro (RJ), Brazil.

Bullous pemphigoid and neurological disease: statistics from a dermatology service^* * Work performed at Pedro Ernesto University Hospital - Rio de Janeiro State University (HUPE-UERJ) - Rio de Janeiro (RJ), Brazil.