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DERMATOPATHOLOGY • An. Bras. Dermatol. 97 (4) • Jul-Aug 2022 • https://doi.org/10.1016/j.abd.2021.10.004   copy

Breast carcinoma metastasis and Wolf’s isotopic response★ ★ Study conducted at the Irmandade da Santa Casa de Misericórdia de Porto Alegre, Porto Alegre, RS, Brazil.

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Abstract

Wolf’s isotopic phenomenon occurs when a new dermatosis appears on a site that has already healed from a previous dermatological disease of another etiology. This report describes the case of a 44-year-old female patient undergoing treatment for breast carcinoma who recently had brownish erythematous lesions appearing on the scar region of previous herpes zoster on the right hemithorax. Histopathology and immunohistochemistry examination confirmed skin metastasis of breast cancer. Herpes zoster scars require attention due to the possibility of an isotopic response as a facilitating factor in some dermatoses, sometimes severe ones, such as neoplasms.

KEYWORDS
Breast neoplasms; Herpes zoster; Neoplasm metastasis; Skin neoplasms; Varicella-Zoster virus infection

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