| Imakado S,
et al 66. Imakado S, Sato H, Hamada K. Two cases of subungueal melanoma in situ. J Dermatol. 2008;35:754-8.
|
2 |
Dermoscopic examination of the site of Hutchinson's sign showed irregular pigmentation on the ridge. Nail plate dermoscopy not described. |
MM in situ
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| Gencoglan
G, et al33. Gencoglan G, Gerceker-Turk B, Kilinc-Karaarslan I, Akalin T, Ozdemir F. Dermoscopic findings in Laugier-Hunziker syndrome. Arch Dermatol. 2007;143:631-633
|
1 |
Homogeneous, brownish, regular bandlike pigmentations with indistinct borders were seen on 4 toenails |
LHS |
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| Antonovich
DD, et al 77. Antonovich DD, Grin C, Grant-Kels JM. Childhood subungual melanoma in situ in diffuse nail melanosis beginning as expanding longitudinal melanonychia. Pediatr Dermatol. 2005;22:210-2.
|
1 |
With dermoscopy the pigmentation was observed as streaky and irregular. |
MM in situ |
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| Caseret AS,
et al44. Caseret AS, Skowron F, Viallard AM, Balme B, Thomas L. Subungual blue nevus. J Am Acad Dermatol. 2003;49:310-2.
|
1 |
Homogeneous blue blotch and a regularly-pigmented grayish longitudinal melanonychia |
Blue nevus |
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| Iorizzo M,
et al 88. Iorizzo M, Tosti A, Di Chiacchio N, Hirata SH, Misciali C, Michalany N, et al. Nail melanoma in children: differential diagnosis and management. Dermatol Clin. 2008;34:974-8.
|
2 |
C1: Dark brown to gray background with longitudinal and irregular parallel lines. Edges appeared ill-defined |
MM in situ |
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| C2: No nail plate dermoscopy |
| |
| Hirata SH, et al55. Hirata SH, Yamada S, Almeida FA, Enokihara MY, Rosa IP, Enokihara MM, et al. Dermoscopic examination of the nail bed and matrix. Int J Dermatol. 2006;45:28-30.
|
10 |
C1: Brown coloration of the background, brown-black regular lines |
C1: TMH |
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| C2: Brown coloration of the background, regular lines |
C2: TMH |
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| C3: Grayish and brown coloration of the background, regular lines |
C3: TMH |
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| C4: Grayish and brown coloration of the background, regular lines |
C4: TMH |
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| C5: Brown coloration of the background, brown-black regular lines |
C5: JMN |
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| C6: Black coloration of the background |
C6:TMH |
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| C7: Grayish and brown coloration of the background, regular lines |
C7:CH |
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| C8: Grayish and brown coloration of the background, regular lines |
C8:CH |
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| C9: Grayish and brown coloration of the background, regular lines |
C9:CH |
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| C10: Brown coloration of the background, black regular lines |
C10: OC |
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|
| Hass N, et al 22. Haas N, Henz BM. Pitfall in pigmentation: pseudopods in the nail plate. Dermatol Surg 2002;28:966-7
|
1 |
18 individual pseudopods protruded along its longitudinal axis, up to 1.1 mm in length and 0.2 mm wide and of straight or twisted shape |
Hemorrhage |
| Kawabata Y,
et al 1111. Kawabata Y, Ohara K, Hino H, Tamaki K. Two kinds of Hutchinson's sign, benign and malignant. J Am Acad Dermatol. 2001;44:305-7.
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24 |
|
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| 6 MM: Initially longitudinal pigmented streaks in the nail plate which increased in breadth, finally involving the whole nail plate, without deformities. Hutchinson's sign was observed in all cases. |
6 MM |
| |
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| 18 BMN: 15 showed partial pigmentation in the nail plate, and in 3 the entire nail plate was involved, without deformities. Pigmented macu-les of the fingertip were observed in the same 3 cases and another 2 cases. |
18 BMN |
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| However the surface profiles of the hyponychial pigmentation of subungual melanoma obtained by the dermoscope were different from those of BMN, although dermoscopic features of the nail plates are indistinguishable. The pattern of pigmentation of BMN had a brushy linear structure across the skin marks. In contrast, subungual melanoma in situ exhibited haphazard pigmentation distributed in a disorderly fashion over the entire surface. |
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| Ronger S,
et al 1 |
148 |
Melanoma (20 cases): association of brown pigmentation of the background (19/20; 95%) with longitudinal brown to black lines irregular in their coloration, spacing, thickness and parallelism. The irregular pattern of the lines was significantly associated with melanoma when compared with all other diagnoses (P=.001, taken either individually or as a group (P=.001 in all 5 differential diagnoses). Melanoma shared with melanocytic nevus the brown coloration of the background. |
20 MM |
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Melanocytic nevus (37 cases): brown background (37/37; 100%) and the regular pattern of the longitudinal lines (35/37; 95%) . The presence of these lines, regular in their thickness, spacing, coloration, and parallelism, was found statistically sufficient to distinguish nevus from melanoma (P=.001). |
37BMN |
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Drug-induced nail pigmentation (16cases): grayish coloration of the background (15/16; 94%) and the presence of thin longitudinal gray lines with regular thickness, spacing, coloration and absence of parallelism disruption. These dermoscopic findings were no different from the ones observed in ungual lentigo or ethnic-type pigmentation, but significantly differed from melanoma (P=.001). |
16 DHNP |
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Nail apparatus lentigo (45 cases): grayish coloration of the background (44/45; 98%) and the presence of thin longitudinal gray lines, regular in their coloration, thickness and spacing (42/45; 93%). The presence of these 2 criteria significantly differentiated nail lentigo from melanoma (P=.001). |
45 NAP |
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Ethnic-type pigmentation (8 cases): The patterns in these cases were similar to those previously described in ungual lentigo and drug induced nail pigmentation, but significantly different from those of melanoma (P=.001). The two characteristic dermoscopic features of ethnic-type nail pigmentation were the grayish background (7/8; 87.5%) and the thin, regular gray lines (7/8; 87.5%). |
8ETP |
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Subungual hemorrhage (22 cases): well-defined, rounded proximal edge and a purple to brown coloration were observed in all cases of subungual hemorrhages (22/22; 100%). |
22 SH |
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| Bilemjian
APJ, et al 10 |
2 |
C1: 1st right digit : Lateral side: A light and dark brown color pigmentation, distributed in a linear and parallel fashion throughout the nail from the cuticle to the free edge. |
C1: MM in situ |
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| Medial part: A totally amorphous and irregular area, affecting the proximal nail fold - the micro-Huntchinson sign. |
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| C2: 5th left digit: Brown parallel homogeneous longitudinal lines; regular in space, width and color. |
C2: TMH |
