Nowadays alopecia areata is considered an autoimmune disease with genetic substrate. The clinical, histopathological, therapeutic and possible physiopathological mechanisms are discussed. The therapeutic approach, especially for the severe forms is considered with emphasis on the methods based on immunomodulation by drugs, diphenylcyclopropenone and squaric acid dibutylester and its possible mechanisms of action are discussed.
Alopecia; Alopecia areata; Review literature
