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CD30-positive cutaneous lymphoma: report of four cases with an emphasis on clinicopathological correlations* * Work performed at Hospital Federal de Bonsucesso and ID-Investigação em Dermatologia - Rio de Janeiro (RJ), Brazil.

Abstract:

The classification of cutaneous lymphomas is multidisciplinary and requires the correlation between clinical, histopathological, immunohistochemical, and molecular diagnostic elements. In this article, we present four different cases of CD30-positive T-cell lymphoma with cutaneous manifestations. We compare cases with definitive diagnosis of papulosis lymphomatoid type C, primary cutaneous anaplastic large T-cell lymphoma, systemic anaplastic large T-cell lymphoma with secondary skin involvement, and mycosis fungoides with large cell transformation, highlighting the importance of clinicopathological correlation to classify these cases.

Keywords:
Anaplastic large cell lymphoma; Cutaneous T-cell lymphoma; Lymphomatoid papulosis; Lymphoproliferative disorders; Mycosis fungoides; Primary cutaneous anaplastic large cell lymphoma

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