In the past years, in Brazil and in developed countries, obesity has become a major public health problem. It was identified that besides DM2 and metabolic syndrome other clinical entities were associated with insulin resistance. In this review we describe some of these alterations emphasizing nonalcoholic fatty liver disease, but also including polycistic ovary disease, hyperuricemia, chronic renal failure, heart failure, cognitive decline and cancer.
Metabolic syndrome; Nonalcoholic fatty liver disease; Polycystic ovaries syndrome; Hyperuricemia; Chronic renal disease; Heart failure; Cognitive decline; Cancer
