Xantogranuloma is a histiocytic disease, characterized by yellowish lesions affecting the epidermis or the dermis, with or without hematological abnormalities and malignancy. The purpose of this paper is to report a 39-year-old woman with bilateral, progressive, painless swelling in both eyelids and anterior orbit, onset 6 years ago, with no systemic alterations. Histology of the excised tissue showed dermis, muscles and orbital fat with xantomatous histiocytes and "Touton" giant cells. The diagnosis was xantogranuloma of the adult. The authors call attention to other differential diagnosis and the necessity of periodical examinations because of the possibility of associated malignancies and systemic diseases.
Histiocytes; Granuloma; Eyelid neoplasms; Orbital neoplasms; Blepharoptosis; Female
