PURPOSE: To report the use of intravitreal injection of triamcinolone acetonide in the acute phase of Vogt-Koyanagi-Harada's disease. METHODS: Nine eyes from five patients in the acute phase of Vogt-Koyanagi-Harada's disease with serous retinal detachments were treated with a single 4-mg intravitreal injection of triamcinolone acetonide. The following parameters were evaluated: visual acuity, intraocular pressure, as well as the height of the serous retinal detachment using optical coherence tomography. RESULTS: Optical coherence tomography images showed a marked decrease in the retinal detachment in the first week after the injection with subsequent return to normal retinal thickness in all eyes. Follow-up ranged from 5 to 12 months with a mean of 7.8 months. No complications were observed. CONCLUSIONS: Intravitreal triamcinolone acetonide provides short-term improvement in visual acuity and serous retinal detachments associated with Vogt-Koyanagi-Harada's disease. These findings should be followed by further studies to evaluate long-term effects.
Retinal detachment; Uveomeningoencephalitic syndrome; Triamcinolone; Tomography, optical coherence
