Metástase de íris de câncer sistêmico: relato de três casos

A maioria das metástases oculares do câncer sistêmico são encontrados na coroide. As metástases para a íris são incomuns, podendo se manifestar como nódulo estromal, espessamento de íris de limites mal definidos ou como uma iridociclite ou hifema. Relatamos 3 pacientes com lesão de íris e história pregressa de câncer sistêmico. Enfatizamos a dificuldade no diagnóstico e raridade dessas lesões comparando com relatos anteriores.

Descritores:
Neoplasias da íris/metástase neoplásica; Relatos de casos

Autoria

Patrícia Correa de Mello Corresponding author: Patricia C. de Mello. Praia de Botafogo, 206 - Rio de Janeiro, RJ - 22250-040 Brazil - E-mail: paticma@gmail.com

Serviço de Oftalmologia, Hospital Federal dos Servidores do Estado do Rio de Janeiro, Rio de Janeiro, RJ, Brazil. Hospital Federal dos Servidores do Estado do Rio de JaneiroBrazilRio de Janeiro, RJ, BrazilServiço de Oftalmologia, Hospital Federal dos Servidores do Estado do Rio de Janeiro, Rio de Janeiro, RJ, Brazil.

Setor de Retina e Vítreo, Instituto Brasileiro de Oftalmologia (IBOL), Rio de Janeiro, RJ, Brazil.Instituto Brasileiro de OftalmologiaBrazilRio de Janeiro, RJ, BrazilSetor de Retina e Vítreo, Instituto Brasileiro de Oftalmologia (IBOL), Rio de Janeiro, RJ, Brazil.

Setor de Tumores, Departamento de Oftalmologia e Ciências Visuais, Escola Paulista de Medicina (EPM), Universidade Federal de São Paulo (UNIFESP), São Paulo, SP, Brazil.Universidade Federal de São PauloBrazilSão Paulo, SP, BrazilSetor de Tumores, Departamento de Oftalmologia e Ciências Visuais, Escola Paulista de Medicina (EPM), Universidade Federal de São Paulo (UNIFESP), São Paulo, SP, Brazil.

Oswaldo Ferreira Moura Brasil

André Vidoris

Melina Correia Morales

Rubens N. Belfort

Corresponding author: Patricia C. de Mello. Praia de Botafogo, 206 - Rio de Janeiro, RJ - 22250-040 Brazil - E-mail: paticma@gmail.com

Disclosure of potential conflicts of interest: None of the authors have any potential conflict of interest to disclose.

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Figuras

Figuras (3)

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Figure 1
Case 1. A) Photography demonstrating a 7 × 4-mm pinkish-yellow mass from 1 to 5 o'clock with intrinsic friable vessels. A band of tissue was observed from 7 to 9 o'clock in the anterior chamber. B) Ultrasound biomicroscopy (UBM) image of an iridociliary mass with homogeneous reflectivity and areas of internal hyporeflective spaces within the tumor. C and D) Post-treatment images demonstrating shrinkage of the lesion.

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Figure 2
Case 2. A) Photograph of a white pearl mass in the temporal upper quadrant associated with bulging of the iris superiorly. Intense anterior chamber inflammation with 3+/4+ cells was observed with an inferior white hypopyon without keratic precipitates. B) UBM image of the lesion with heterogeneous reflectivity. C) Lesion after treatment. D) Histopathology.

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Figure 3
Case 3. A) Biomicroscopy image demonstrating a pink iris mass from 1 to 3 o'clock with intrinsic vessels. B and C) Ultrasound biomicroscopy (UBM) demonstrating a mass with homogeneous reflectivity and areas of internal hyporeflective spaces. D) UBM after treatment showing shrinkage of the lesion.

Figure 1 Case 1. A) Photography demonstrating a 7 × 4-mm pinkish-yellow mass from 1 to 5 o'clock with intrinsic friable vessels. A band of tissue was observed from 7 to 9 o'clock in the anterior chamber. B) Ultrasound biomicroscopy (UBM) image of an iridociliary mass with homogeneous reflectivity and areas of internal hyporeflective spaces within the tumor. C and D) Post-treatment images demonstrating shrinkage of the lesion.

Figure 2 Case 2. A) Photograph of a white pearl mass in the temporal upper quadrant associated with bulging of the iris superiorly. Intense anterior chamber inflammation with 3+/4+ cells was observed with an inferior white hypopyon without keratic precipitates. B) UBM image of the lesion with heterogeneous reflectivity. C) Lesion after treatment. D) Histopathology.

Figure 3 Case 3. A) Biomicroscopy image demonstrating a pink iris mass from 1 to 3 o'clock with intrinsic vessels. B and C) Ultrasound biomicroscopy (UBM) demonstrating a mass with homogeneous reflectivity and areas of internal hyporeflective spaces. D) UBM after treatment showing shrinkage of the lesion.

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Metástase de íris de câncer sistêmico: relato de três casos

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[1] Corresponding author: Patricia C. de Mello. Praia de Botafogo, 206 - Rio de Janeiro, RJ - 22250-040 Brazil - E-mail: paticma@gmail.com