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Triangulation of an end-to-end anastomosis using oral mucosa for urethral reconstruction: experimental study in dogs

Oral mucosa has been considered an excellent alternative method to substitute for urethral tissue. OBJECTIVE: To investigate the results of a triangulation of an end-to-end anastomosis using oral mucosa for urethral reconstruction. METHODS: Twelve healthy dogs of no defined race weighing between 13 and 17 kg were anesthetized and an urethral catheter was maintained during the whole surgery. First, a piece of oral mucosa was removed from the superior lip and kept in saline solution containing aqueous chloramphenicol. Then, a 2 cm fragment of the urethra from the penis was removed and the oral mucosa was used to reconstruct the urethra. RESULTS: After 60 days we observed stenosis in 25% of the dogs. There were also urethral-cutaneous fistulas and constrast leakage at the site of anastomosis. CONCLUSION: The triangulation of an end-to-end anastomosis using oral mucosa for urethral reconstruction does not prevent the occurrence of stenosis.

Urethra. Buccal mucosa; Urethral stricture; Urethral anastomosis


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