We performed an experimental study with the purpose to verify if the use of pilocarpine produces a difference in the velocity of the hepatic regeneration. It’s known that in salivectomized rats the regeneration of the liver gets decreased. It’s also known that the pilocarpine increases the salivation of this animals. In the first phase we determined the dose of pilocarpine to be used. In the second phase of the project we realized the hepactomies, parching 52,8% of the liver on average. Our results demonstrated that the pilocarpine decreases the total loss of body wheight at the end of 48 hours after partial hepactomies (p=0,55) and also decreases the hepatic edema during its regeneration (p= 0,11), but we observed a greater wheight of the liver in regeneration in the control group in the first day (p=0,016).
Pilocarpine; Hepatic regeneration
