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Histological analysis of the viability of half ovary autologous transplantation in retroperitoneal of rats

PURPOSE: To observe the indicative morphological signs of restorable ovarian function in retroperitoneal half-ovaries transplant autologous in Wistar rats. METHODS: 48 bilaterally oophorectomized female Wistar rats were used. Distributed by 6 groups, according to pos-operative timing, which was done after total removal, from the selftransplanted anatomical region (ovary and psoas muscle) The total ovaries were fixed in formalin during 24 hours, in 4º Celsius. The morphometric parameters useed in this work were the presence or absence of ovarian follicles, neovascularization, corpus luteum and granulation tissue. RESULTS: The results showed presence of ovarian follicles, corpus luteum and neovascularization in all groups. Observation of granulation tissue were more intense visualized in the early groups. CONCLUSION: The selftransplanted ovaries showed morphological signs of restorable of the ovarian function. Findings suggest that the implantation may allowed a higher survive of them in the retroperitoneum.

Ovary; Histology; Transplantation, Autologous; Rats


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