Oral transit time in Alzheimer’s disease

Descriptive, cross-sectional, observational study conducted with a sample of 34 elderly aged 65-98 years, with AD at different stages. Participants were observed using videofluoroscopy of swallowing while ingesting pudding consistency, using the Kinovea timing program. Data were statistically analyzed at 5% significance level.

Results

Participants with Clinical Dementia Rating - CDR 3 presented longer OTT compared with those with CDR 1, with means of 3.09 s (SD = 0.91) and 1.17 s (SD = 1.10), respectively. Individuals aged 90-100 years presented longer OTT than those aged 60-79 years, means of 3.90 s and 1.28 s, respectively.

Conclusion

Individuals with dementia and advanced aged present longer OTT for pudding consistency and should receive special attention from family members and caregivers.

Keywords:
Alzheimer’s disease; Deglutition; Swallowing disorder; Fluoroscopy; Digestive system physiological phenomena

Variables analyzed	n	%	Minimum	Maximum	Mean	Median	Standard Deviation	p-value
CDR
1	14	41.2	0.24	4.32	1.17	0.84	1.01	<0.001 ¹ 1 Tukey’s test
2	12	35.3	0.57	3.70	1.69	1.50	0.88
3	8	23.5	1.56	4.47	3.09	3.29	0.91
Gender
Male	9	26.5	0.43	3.47	1.24	0.77	1.02	0.104 ² 2 Non-parametric tests
Female	25	73.5	0.24	4.47	2.01	1.56	1.23	0.104 ² 2 Non-parametric tests
Age group
60-79 years	7	29.6	0.40	3.41	1.28	1.09	0.29	0.032 ³ 3 Tukey’s test
80-89 years	20	58.8	0.24	4.31	1.61	1.25	1.07
90-100 years	7	26.6	1.79	4.47	3.90	2.61	1.91

Variables	Difference between means OTT	p-value
CDR
1 x 2	-0.51	0.396 ¹ 1 Tukey’s test
2 x 3	-1.92	0.010 ¹ 1 Tukey’s test
1 x 3	-1.41	<0.001 ¹ 1 Tukey’s test
Age group (years)
60/79 x 80/89	-0.34	0.769 ¹ 1 Tukey’s test
80/89 x 90/100	-1.28	0.033 ¹ 1 Tukey’s test
60/79 x 90/100	-1.62	0.026 ¹ 1 Tukey’s test

Academia Brasileira de Audiologia Rua Itapeva, 202, conjunto 61, CEP 01332-000, Tel.: (11) 3253-8711, Fax: (11) 3253-8473 - São Paulo - SP - Brazil
E-mail: revista@audiologiabrasil.org.br

Acompanhe os números deste periódico no seu leitor de RSS

[1] Conflict of interests: No.