Open-access PRESENCE OF A CORONAVIRUS ASSOCIATED WITH AN OUTBREAK OF GASTROENTERITIS IN SWINE, IN THE COUNTY OF MAIRINQUE, SÃO PAULO, BRAZIL, IN 1988

ABSTRACT

A gastroenteritis outbreak on a pig breeding farm in Mairinque, São Paulo, Brazil, in 1988, is reported. The animais showed clinicai signs of sanguinolent diarrhoea, inappetance, prostation, dehydration, dyspnoea and death. Negatively and positively stained electron microscopy preparations of faeces and small-intestine samples revealed theconstant presence of coronaviruslike particles. The constant association of such particles with the symptomatology described, the necropsy related to gastroenteritisand histological lesions under light microscopy in theexamined materiais suggest that thegastroenteritis outbreak was caused by coronavirus infection.

KEY WORDS:
Coronavirus; swine; gastroenteritis

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Instituto Biológico Av. Conselheiro Rodrigues Alves, 1252 - Vila Mariana - São Paulo - SP, 04014-002 - São Paulo - SP - Brazil
E-mail: arquivos@biologico.sp.gov.br
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