Plasmacytoma of head and neck as initial presentation of multiple myeloma

Plasmocitoma da cabeça e pescoço como apresentação inicial de mieloma múltiplo

IMAGES IN NEUROLOGY

Plasmacytoma of head and neck as initial presentation of multiple myeloma

Plasmocitoma da cabeça e pescoço como apresentação inicial de mieloma múltiplo

Rodrigo Jorge de Oliveira^I; Fabiano Reis^I; Atul Kumar Taneja^I; Luciano de Souza Queiroz^II; Verônica de Araújo Zanardi^I

^IDepartment of Radiology of the Clinics Hospital of the State University of Campinas, Faculty of Medical Sciences, Campinas SP, Brazil

^IIDepartment of Pathology of the Clinics Hospital of the State University of Campinas, Faculty of Medical Sciences, Campinas SP, Brazil

^{Correspondence}

45-year-old female with headache and facial tumor growing since 16 months ago. Diagnostic imaging demonstrated a large lesion on the right greater sphenoid wing, extending into the masticator space, nasopharynx, nasal cavity, clivus, sphenoid and maxillary sinuses, and to the anterior and middle cranial fossae.

Histological analysis confirmed the diagnosis of plasmacytoma and later the bone marrow biopsy diagnosed multiple myeloma.

Multiple myeloma compromising the skull base is difficult to diagnose, specially when its onset is a head and neck plasmacytoma, wich is uncommon and overlaps other head and neck tumoral conditions that also present as large extra-axial masses.

Received 20 July 2010

Received in final form 9 August 2010

Accepted 16 August 2010

• 1. Lin C, Luciani A, Belhadj K, et al. Patients with plasma cell disorders examined at whole-body dynamic contrast-enhanced magnetic resonance imaging. Radiology 2009;250:905-915.
• 2. Cerase A, Tarantino A, Gozzetti A, et al. Intracranial involvement in plasmocytomas and multiple myeloma: a pictorial essay. Neuroradiology 2008;50:665-674 .
• 3. Angtuaco JC, Fassas ABT, Walker R, Sethi R, Barlogie B. Multiple myeloma: clinical review and diagnostic imaging. Radiology 2004;231:11-23.
• 4. Provenzale JM, Schaefer P, Traweek ST, et al. Craniocerebral plasmacytoma: MR features. AJNR Am J Neuroradiol 1997;18:389-392.

Publication Dates

• Publication in this collection
  18 Feb 2011
• Date of issue
  Feb 2011