Tegretol (5-carbanyl-5H-dibenzo-b,L-azepina) was used experimentally in the theatment of 68 epileptic patients; 54 had temporal lobe epilepsy (42 had psychomotor and 12 had complex seizures), 11 had focal non-temporal lobe epilepsy and 3 had P.M. epilepsy. Satisfactory results were obtained in 82 per cent of the 65 patients with focal epilepsy, but failure of the treatment was observed in all cases of P.M. epilepsy. The drug has a very good influence on the critical and intercritical mental phenomena which are frequently present in these patients. The personality of the patient improves and he becomes better adjusted to his family, his work or school. The action of the electroencephalogram is not very clear. Some records were improved, others remained inaltered. The dosage used varied from 400 to 600 mg daily in the great majority of cases. Side effects were not common and not severe. One patient developed transitory drop in leukocytes. Tegretol is a drug with anticonvulsivant and psychotropic properties, and has a very pronounced effect on focal epilepsy particularly on psychomotor seizures.