Error related negativity and multi-source interference task in children with attention deficit hyperactivity disorder-combined type

La negatividad relacionada al error en una tarea de interferencia multifuente en niños con trastorno por déficit de atención-hiperactividad tipo combinado

Objective

To compare performance of children with attention deficit hyperactivity disorders-combined (ADHD-C) type with control children in multi-source interference task (MSIT) evaluated by means of error related negativity (ERN).

Method

We studied 12 children with ADHD-C type with a median age of 7 years, control children were age- and gender-matched. Children performed MSIT and simultaneous recording of ERN.

Results

We found no differences in MSIT parameters among groups. We found no differences in ERN variables between groups. We found a significant association of ERN amplitude with MSIT in children with ADHD-C type. Some correlation went in positive direction (frequency of hits and MSIT amplitude), and others in negative direction (frequency of errors and RT in MSIT).

Conclusion

Children with ADHD-C type exhibited a significant association between ERN amplitude with MSIT. These results underline participation of a cingulo-fronto-parietal network and could help in the comprehension of pathophysiological mechanisms of ADHD.

attention deficit hyperactivity disorder; multi-source interference task; event related potentials; error-related negativity; cingulo-fronto-parietal network