Local IgG synthesis in three pediatric patients with cuban epidemic neuropathy

Sintesis local de IgG en tres pacientes pediátricos com neuropatía epidêmica cubana

Alberto Dorta-Contreras^I; Eric Martínez Torres^II; Carlos Dotres-Martínez^II

^ILaboratório Inmunología, Hospital Pediátrico San Miguel, Ciudad de La Habana, Cuba

^IIHospital Wiliam Soler, Ciudad de La Habana, Cuba

ABSTRACT

Three pediatric patients with Cuban epidemic neuropathy were studied. Cerebrospinal fluid and sera were simultaneously obtained. Albumin and IgG were quantified by immunodifusion. Albumin quotient and local synthesis of IgG were calculated by Reiber/Felgenhauer formula. A patient with optic neuritis had a dysfunction of the blood-cerebrospinal fluid barrier. All the group had local synthesis of IgG.

Key words:Cuban epidemic neuropathy, optic neuritis, peripheral neuropathy, cerebrospinal fluid, intrathecal synthesis.

RESUMEN

Se estudiaron tres pacientes pediátricos con neuropatia epidêmica cubana. Se obtuvieron suero y liquido cefalorraquídeo simultaneamente. Se cuantificaran los niveles de albúmina e IgG por inmunodifusion radial. Se calculo la razón albúmina y la fórmula de Reiber/Felgenhauer. Un paciente con neuritis óptica tuvo una disfunción de la barrera sangre-líquido cefaloraquídeo. Todo el grupo tuvo síntesis local de IgG.

Palabras Claves: neuropatía epidêmica cubana, neuritis óptica, neuropatía periférica, líquido cefalorraquídeo, IgG, albúmina, síntesis intratecal.

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Aceite: 16-setembro-1995.

Dr. Alberto Dorta-Contreras - Laboratório Inmunologia, Hospital Pediátrico San Miguel - Apartado 10049 -11000 Ciudad de La Habana - Cuba.

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Local IgG synthesis in three pediatric patients with cuban epidemic neuropathy

Sintesis local de IgG en tres pacientes pediátricos com neuropatía epidêmica cubana

Publication Dates

• Publication in this collection
  07 Dec 2010
• Date of issue
  Mar 1996