Movement is the final expression of the harmonius activation of multiple brain and muscle systems. In nature, movement measures primary responses of profound adaptative value such as reproduction, predation and flight, among others. The description of movements as motor acts or patterns was first the task of Ethology. With the recent advances in the Neurosciences, a neuroethological approach is proposed today for research in this area. When dysfunctions in motion occur, practically the same brain and muscle systems are utilized, but in an aberrant manner both in time and space. In the present review, we illustrate the major systems involved in normal motor control, in particular the cortex, basal ganglia, cerebellum, brain stem, medulla, and receptor and effector muscle periphery.