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Epilepsy in cerebral tumors

In 411 cases of cerebral tumors, 86 (19,4%) with epileptic manifestations were studied. The duration, the manifestations and the severity of epilepsy, in regard to the nature and site of the tumor, were investigated. The analysis of the results lead the authors to the following conclusions: 1) 19.4% of the cerebral tumors showed epileptic symptoms; 2) oligodendroglioma, metastatic carcinomas and glioblastoma multiforme were, in this order, the most epileptogenic tumors; 3) the frontal, parietal and temporal areas were, in this order, the most epileptogenic localizations; 4) concerning the duration of epilepsy, the metastatic carcinomas were more frequent when the duration of epilepsy was lower than one year, while the astrocytoma were more frequent in the cases with more than three years; regarding the location, the frontal area was more frequent in the first group and the temporal area in the second one; 5) regarding the frequency of seizures, oligodendroglioma and meningeoma, and the frontotemporal and falx cerebri locations were found more frequently in the more severe cases; 6) concerning the pattern of epileptic manifestations, cranio-pharyngiomas and meduloblastomas were the tumors that induced most seizure without aura; in these cases the pituitary region and the posterior fossa were the more frequent sites; 7) metastatic carcinomas and meningeomas, as well as frontoparietal and parietal areas, were most frequently found in the cases with jacksonian seizures.


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