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Hereditary angioneurotic oedema and visceral epilepsy

A case of familiar angioneurotic oedema is reported in which, besides the cutaneous, gastro-intestinal and respiratory symptoms, there were neurological manifestations of visceral epilepsy and focal facial seizures, with localized eletroencephalographic alterations. Dosage of total complement (CH50) establised the diagnosis of familiar angioneurotic oedema. However, considering clinical manifestations, EEG records and therapeutic results the diagnosis of visceral epilepsy seems also justified. Disappearance of all symptoms with anticonvulsive medication in adequate dosage is of special interest and should be investigated in other cases. Considering the clinical similarity of abdominal pain due to visceral epilepsy and to angioneurotic oedema, as well as the simultaneous occurrence in the reported case of angioneurotic hereditary oedema and abdominal epilepsy, further research is suggested in order to establish a possible relationship between these two entities.


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