| Leonard S et al(14) 2017 |
3 |
A (90,9%) |
n=11 8 to 21 years |
Intensive training program (ITP) mobile app was used by participants to produce daily self-recorded videos (“selfies”) of medication administration and receive provider messages and feedback about adherence. Providers monitored “selfies” recorded and sent messages to patients every 7 to 10 days. |
Participants exhibited a clinically relevant decrease in serum ferritin, which trended toward statistical significance. The mobile ITP was feasibly implemented in a clinical setting; in addition, high levels of compliance, disease knowledge retention, and acceptance encourage were observed. |
Mobile technology intervention can be easily integrated to provide education to youth as well as map disease knowledge and compliance rates for pediatric patients receiving daily iron chelation therapy. |
| Crosby LE et al.(6) 2016 |
3 |
A (88,6%) |
n= 70 16 to 24 years |
Development study of the iManage application consisting of the steps: identification of barriers and development of App for smartphone, sessions of co-creation (participant and professionals) for validation of themes, characteristics and interface of App; Usability testing with the iManage prototype and institutional approval. |
- The prototype presented satisfactory usability, contributed to improving the practice of self-care by attending to the needs and experiences of the participants, supporting communication between peers and professionals. |
Apps can be used clinically to understand the frequency and intensity of symptoms and the effectiveness of self-care strategies. Future research should include a representative sample with a randomized clinical trial. |
| Badawy MS et al.(7) 2016 |
3 |
A (86,4%) |
n= 107 12 to 22 years |
Study encompassing three phases: 1st) development of a questionnaire (technological domains, accessibility, daily medications and barriers to adherence); 2nd) validation of the instrument by specialists; 3rd) App development for Smartphones |
- Preference for Apps which prioritized health education actions to provide information on chronic condition, reminders for medication use and social interactions (friends and family). |
Investtement needed in educational strategies drawing on digital technologies to improve communication between health professionals and patients. |
| Gupta N et al.(15) 2016 |
4 |
Not applicable |
n= 22 4 to 17 years |
Study of a qualitative approach consisting of cognitive interviews with the participants and evaluation of comprehension and usability of the electronic scale (Faces Pain Scale-Revised - FPS-R). |
- Participants demonstrated familiarity with touchscreen devices (smartphones) and parents relied on this ability of their children. - Participants aged 4 to 6 years old did not have a clear understanding and ability to use the electronic scale for pain. - Children between 7 and 8 years old needed support from parents. - Participants over 9 years of age used the pain scale by themselves. |
The scales developed for the electronic version should have simplified instructions, with terms that aid users comprehension, considering the biological, psychosocial and cultural characteristics of the target population. |
| Schatz J et al.(16) 2015 |
1 |
A (93,2%) |
n=46 8 to 22 years |
Randomized clinical trial. The control and intervention groups received training in coping skills. |
- The intervention with smartphone support represented more active coping attempts. - Data from the electronic diary indicated that when participants adopted the skills developed from cognitive-behavioral therapy, there was reduction of pain on subsequent days. |
Future research for Apps development should include usability assessment. |
| Jonassaint CR et al.(8) 2015 |
3 |
A (84,1%) |
n=15 12 to 54 years |
Participants used Sickle cell disease Mobile Application to Record symptoms via Technology (SMART) to record pain, symptoms, and control strategies and received automatic messages with guidelines on how to proceed in the face of disease intercurrences. |
- The SMART app was evaluated as an effective tool to assess pain and other day-to-day symptoms, contributing to self-care and control behaviors. |
Applications should incorporate functions promoting educational, games (gamification), feedback and interaction among users. |
| Bakshi N et al.(17) 2015 |
3 |
A (91%) |
n=10 15 to 22 years |
Study of adaptation of an “e-Ouch” pain diary of rheumatoid arthritis for sickle cell disease, encompassing the phases from the e-diary, content validation, cognitive interviews, elaboration of a preliminary conceptual model, e-diary development and evaluation. |
- The multidimensional electronic e-diary for pain received a positive evaluation, because it integrated interesting layout and content for the users, who could access it through a laptop. |
Socioeconomic status of the population should be considered in the development of an e-diary, with specific features that bring the reality of the target population as well as the availability of access to technologies and networks. |
| Estepp JH et al.(18) 2014 |
3 |
A (91%) |
n=55 up to 19 years |
A tool that sends electronic messages to the patient’s cell phone to remind him/her to take his/her medication is introduced: “Scheduled Instant Messaging Over the Network” (SIMON1) |
- The Simon1 App was considered a viable and effective tool to improve adherence to the treatment of daily hydroxyurea therapy, improving hematological parameters. |
Future work should include extending this technology to other populations with different chronic conditions that require daily use of medication. Continue... |
| Continuation. Creary SE et al.(19) 2014 |
3 |
A (95,4%) |
n= 14 1 to 22 years |
Study on the development and evaluation of the Electronic version of “Eletronic directly observed therapy” (DOT) for hydroxyurea drug therapy. To evaluate the acceptance of the electronic version, participants were asked to record qualitative feedback of it. |
- The electronic version for adherence to hydroxyurea (DOT) presented satisfactory characteristics related to the filling time of daily data and the efficiency of the reminders to make use of the drug, demonstrating good viability and improving adherence. |
The electronic version of the DOT model was recommended because it presents a smaller cost, considering the population minorities. |
| Shah N et al.(20) 2014 |
3 |
A (81,8%) |
n= 117 over 18 years |
Study encompassing two phases: 1) included 100 participants who completed a survey on technology and use of mobile devices for self-management and communication with health professionals. 2) 17 participants tested the usability of the App. |
- The application tested was useful to control pain, demonstrating to be beneficial and practical for self-care and support the communication of patients with professionals. |
Mobile technology should be considered as an appropriate strategy to support the practice of self-care in an individualized way, with guided instructions for use of medication and control of signs and symptoms. |
| Jacob E et al.(21) 2102 |
3 |
A (95,4%) |
n= 31 10 to 17 years |
Study with two pilot tests: 1) ten participants used a smartphone and a record questions on paper. 2) 21 participants used an electronic diary (e-diary) in smartphone to record pain, symptoms, sleep information, thoughts and feelings experienced during the last 12 hours. |
- e-diary improved reporting of symptoms by participants and communication with health professionals. |
The Smartphone should be recommended for children and adolescents who present severe form of the disease, due to the fact that it is easy to use and because it involves the participants in the practices of self-care. |
| Mc Clellan CB et al.(22) 2009 |
3 |
A (95,4%) |
n= 19 8 to 20 years |
Study aimed at recruiting participants who used mobile application for daily pain scale control during a period of two months. Data were monitored by the researchers. Participants received training to develop behavioral skills to deal with their pain (such as breathing and relaxation). |
- Comparison of practical skills rates for enrollment in the device provided important information about the use of electronic monitoring for behavioral interventions. |
Electronic wireless technologies and data transfer are recommended to monitor sickle cell disease symptoms, and they are able to support communication between patients and health care professionals. |
