Enzymatic extraction (Cellulase) after simultaneous ultrasound and microwave treatment |
Nitraria tangutorum juice by-products |
Total phenols content (157.5 mg GAE/g); total flavonoids (101.3 mg QE/g); total anthocyanins (82.3 mg CGE/g). |
Wu et al. (2015) |
Soxhlet enzymatic extraction |
Total phenols content (88.2 mg GAE/g); total flavonoids (72.5 mg QE/g); total anthocyanins (66.4 mg CGE/g) |
Ultrasound-assisted enzymatic extraction |
Total phenols content (126.0 mg GAE/g); total flavonoids (93.0 mg QE/g); total anthocyanins (76.4 mg CGE/g). |
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Total phenols content (97.5 mg GAE/g); total flavonoids (79.6 mg QE/g); total anthocyanins (74.9 mg CGE/g). |
Microwave-assisted enzymatic extraction |
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Enzyme assisted extraction (enzymatic cocktail obtained after SSF of mixture grape pomace and wheat bran with A. niger) |
Grape pomace |
Increases of total phenolics, proanthocyanidins, and anthocyanins of 79.92%, 121.53% and 20.96%, respectively. |
Teles et al. (2019)Teles, A. S. C., Chávez, D. W. H., Oliveira, R. A., Bon, E. P. S., Terzi, S. C., Souza, E. F., Gottschalk, L. M. F., & Tonon, R. V. (2019). Use of grape pomace for the production of hydrolytic enzymes by solid-state fermentation and recovery of its bioactive compounds. Food Research International, 120, 441-448. PMid:31000260. http://dx.doi.org/10.1016/j.foodres.2018.10.083 http://dx.doi.org/10.1016/j.foodres.2018...
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Pre-extraction of polyphenols with ethanol followed by FS using culture medium + polyphenol extract with A. fumigatus |
Orange peel |
Increases of polyphenols and flavonoids of 29 and 26% after 54 and 12 h fermentation, respectively. |
Sepúlveda et al. (2020)Sepúlveda, L., Laredo-Alcalá, E., Buenrostro-Figueroa, J. J., Ascacio-Valdés, J. A., Genisheva, Z., Aguilar, C., & Teixeira, J. (2020). Ellagic acid production using polyphenols from orange peel waste by submerged fermentation. Electronic Journal of Biotechnology, 43, 1-7. http://dx.doi.org/10.1016/j.ejbt.2019.11.002 http://dx.doi.org/10.1016/j.ejbt.2019.11...
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FS with Lactobacillus strains (L. plantarum, L. paracasei, L. fermentum and L. casei) |
Peel and seeds of acerola and guava |
Increases of polyphenols of 173 and 28% and flavonoids of 20 and 22% in acerola and guava residues, respectively, after FS for 120 h. |
Oliveira et al. (2020)Oliveira, S. D., Araújo, C. M., Borges, G. S. C., Lima, M. S., Viera, V. B., Garcia, E. F., Souza, E. L., & Oliveira, M. E. G. (2020). Improvement in physicochemical characteristics, bioactive compounds and antioxidant activity of acerola (Malpighia emarginata D.C.) and guava (Psidium guajava L.) fruit by-products fermented with potentially probiotic lactobacilli. Lebensmittel-Wissenschaft + Technologie, 134, 1-9. http://dx.doi.org/10.1016/j.lwt.2020.110200 http://dx.doi.org/10.1016/j.lwt.2020.110...
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FS using the fungus Calocybe indica. |
Mixture of banana peel powder and defatted peanut residue powder |
Increases of 100% and 142% in total phenolics and total flavonoid content, respectively. |
Kapri et al. (2020)Kapri, M., Singh, U., Behera, S. M., Srivastav, P. P., & Sharma, S. (2020). Nutraceutical augmentation of agro-industrial waste through submerged fermentation using Calocybe indica. Lebensmittel-Wissenschaft + Technologie, 134, 1-9. http://dx.doi.org/10.1016/j.lwt.2020.110156 http://dx.doi.org/10.1016/j.lwt.2020.110...
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SSF with A. niger and extraction with ethanol/water solution (56:44, v/v) and heating at 60 °C |
Avocado seeds |
Increases of polyphenol content of 75% after 314 h of fermentation. |
Yepes-Betancur et al. (2021)Yepes-Betancur, D. P., Márquez-Cardozo, C. J., Cadena-Chamorro, E. M., Martinez-Saldarriaga, J., Torres-León, C., Ascacio-Valdes, A., & Aguilar, C. N. (2021). Solid-state fermentation: Assisted extraction of bioactive compounds from hass avocado seeds. Food and Bioproducts Processing, 126, 155-163. http://dx.doi.org/10.1016/j.fbp.2020.10.012 http://dx.doi.org/10.1016/j.fbp.2020.10....
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SSF A. niger and Saccharomyces cerevisae and extraction with 7:3 v/v ethanol/water mixture using an ultrasound microwave system |
Pomegranate peel |
5-fold higher extraction of ellagic acid with S. cerevisae than that obtained with A. niger and 10-fold higher than that of the |
Moccia et al. (2019)Moccia, F., Flores-Gallegos, A. C., Chávez-González, M. L., Sepúlveda, L., Marzorati, S., Verotta, L., Panzella, L., Ascacio-Valdes, J. A., Aguilar, C. N., & Napolitano, A. (2019). Ellagic acid recovery by solid state fermentation of pomegranate wastes by Aspergillus niger and Saccharomyces cerevisiae: A comparison. Molecules, 24(20), 1-11. PMid:31614997. http://dx.doi.org/10.3390/molecules24203689 http://dx.doi.org/10.3390/molecules24203...
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unfermented material. |
SSF with A. niger followed by extraction with solvents (distilled water, aqueous solutions at 40% and 80% acetone, 40% and 80% ethanol) |
Granadilla seeds |
Increases of polyphenols and flavonoids of 43.6 and 45.8% after 48 and 168 h fermentation, respectively. |
Santos et al. (2020a)Santos, T. R. J., Feitosa, P. R. B., Gualberto, N. C., Narain, N., & Santana, L. C. L. A. (2020a). Improvement of bioactive compounds content in granadilla (Passiflora ligularis) seeds after solid-state fermentation. Food Science & Technology International, 27(3), 234-241. PMid:32772707. http://dx.doi.org/10.1177/1082013220944009 http://dx.doi.org/10.1177/10820132209440...
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SSF with A. niger followed by extraction with solvents (distilled water, aqueous solutions at 40% and 80% acetone, 40% and 80% ethanol) |
Tamarind peel and mixture of tamarind peel and seeds |
For seeds, increases of 524 and 748% of total phenolic and total flavonoid content, respectively. For mixture of seeds and peels, increases of 67% of total phenolic content. |
Santos et al. (2020b)Santos, T. R. J., Vasconcelos, A. G. S., Santana, L. C. L. A., Gualberto, N. C., Buarque Feitosa, P. R., & Pires de Siqueira, A. C. (2020b). Solid-state fermentation as a tool to enhance the polyphenolic compound contents of acidic Tamarindus indica by-products. Biocatalysis and Agricultural Biotechnology, 30, 1-11. http://dx.doi.org/10.1016/j.bcab.2020.101851 http://dx.doi.org/10.1016/j.bcab.2020.10...
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SSF with A. niger followed by extraction with a mixture of hydrochloric acid/methanol/water in an ultrasonic bath |
Sambucus nigra L. and Sambucus ebulus L. berry pomace |
Increases of polyphenols of 18.82% for S. ebulus and 11.11% for S. nigra. |
Dulf et al. (2015)Dulf, F. V., Vodnar, D. C., Dulf, E. H., & Toşa, M. I. (2015). Total phenolic contents, antioxidant activities, and lipid fractions from berry pomaces obtained by solid-state fermentation of two sambucus species with Aspergillus niger. Journal of Agricultural and Food Chemistry, 63(13), 3489-3500. PMid:25787023. http://dx.doi.org/10.1021/acs.jafc.5b00520 http://dx.doi.org/10.1021/acs.jafc.5b005...
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SSF with A. niger followed extraction with water |
Pomegranate peel |
Increases of total polyphenols and total flavonoids of 18.5 and 64.5%, respectively. |
Bind et al. (2014)Bind, A., Singh, S. K., Prakash, V., & Kumar, M. (2014). Evaluation of antioxidants through solid state fermentation. International Journal of Pharmacy and Biological Sciences, 4(1), 104-112.
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SSF with A. niger and R. oligosporus followed by extraction with a mixture of hydrochloric acid/methanol/water in an ultrasonic bath |
Plum fruit by-products |
Total phenolic contents increased by over 30% with R. oligosporus and by >21% with A. niger. |
Dulf et al. (2016)Dulf, F. V., Vodnar, D. C., & Socaciu, C. (2016). Effects of solid-state fermentation with two filamentous fungi on the total phenolic contents, flavonoids, antioxidant activities and lipid fractions of plum fruit (Prunus domestica L.) by-products. Food Chemistry, 209, 27-36. PMid:27173530. http://dx.doi.org/10.1016/j.foodchem.2016.04.016 http://dx.doi.org/10.1016/j.foodchem.201...
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SSF with A. niger and R. oligosporus followed by extraction a mixture of hydrochloric acid/methanol/water in an ultrasonic bath |
Apricot pomace |
With A. niger, increases of total phenolics and total flavonoids of 30 and 12%, respectively. With R. olisgosporus, increases of total phenolic and total flavonoid of 70 and 38%, respectively. |
Dulf et al. (2017)Dulf, F. V., Vodnar, D. C., Dulf, E. H., & Pintea, A. (2017). Phenolic compounds, flavonoids, lipids and antioxidant potential of apricot (Prunus armeniaca L.) pomace fermented by two filamentous fungal strains in solid state system. Chemistry Central Journal, 11(1), 92. PMid:29086904. http://dx.doi.org/10.1186/s13065-017-0323-z http://dx.doi.org/10.1186/s13065-017-032...
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SSF with A. niger and R. oligosporus followed by extraction a mixture of hydrochloric acid/methanol/water in an ultrasonic bath |
Chokeberry pomace |
With A. niger, increases of total phenolics and total flavonoids of 79 and 50%, respectively. With R. olisgosporus, increases of total phenolics and total flavonoids of 87 and 57%, respectively. |
Dulf et al. (2018)Dulf, F. V., Vodnar, D. C., Dulf, E. H., Diaconeasa, Z., & Socaciu, C. (2018). Liberation and recovery of phenolic antioxidants and lipids in chokeberry (Aronia melanocarpa) pomace by solid-state bioprocessing using Aspergillus niger and Rhizopus oligosporus strains. Lebensmittel-Wissenschaft + Technologie, 87, 241-249. http://dx.doi.org/10.1016/j.lwt.2017.08.084 http://dx.doi.org/10.1016/j.lwt.2017.08....
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