The aim of this research was to evaluate the hepatic biochemical profile and the renal enzymatic activity of broiler chicken experimentally intoxicated with aflatoxin and supplemented with sodic montmorilonite on the diet. 528 Cobb’s broiler chickens were used divided in 6 treatments (from 1st to the 42th day of life) as described: (T1) control: normal diet; (T2) diet with 5ppm of aflatoxin; (T3) diet with 0.25% sodic montmorilonite; (T4) diet with 5 ppm of aflatoxin + 0.25% sodic montmorilonite; (T5) diet with 0.5% sodic montmorilonite; (T6) diet with 5 ppm of aflatoxin + 0.5% sodic montmorilonite. The treatment T2 showed significantly decreased levels of uric acid, albumin, cholesterol, creatinine, triglycerides, globulins and total serum proteins and an increase of serum alanine aminotransferase (ALT) activity. Aspartate aminotransferase (AST) did not showed important differences among treatments. In treatments T3 and T5, there were no variations on the biochemical values, when compared to treatment T1. Addition of 0.5% of montmorilonite in the diet (T6), presented better results on the increase of the adsorption of aflatoxin when compared to 0.25% sodic montmorilonite (T4). Clearly, the results showed that high levels of aflatoxin in the diet (5ppm) causes important changes in the serum enzymatic activity of broiler chickens. Also, it was demonstrated that using sodic montmorilonite may be used to avoid risks caused by food contaminated by aflatoxins.
aflatoxin; sodic montmorilonite; broiler chicken; biochemistry profile
